Patent application number | Description | Published |
20090087654 | FILMS CONTAINING MICROLAYER STRUCTURES - Films containing microlayer structures are provided. In a general embodiment, the present disclosure provides an autoclavable film containing a first microlayer of a heat resistant polymer and a second microlayer of a flexible polymer attached to the first microlayer. Each of the first microlayer and the second microlayer has a thickness ranging between about 0.01 microns and about 10 microns. | 04-02-2009 |
20090124963 | BALANCED FLOW DIALYSIS MACHINE - A system and method for balancing flows of renal replacement fluid is disclosed. The method uses pressure controls and pressure sensing devices to more precisely meter and balance the flow of fresh dialysate and spent dialysate. The balancing system may use one or two balancing devices, such as a balance tube, a tortuous path, or a balance chamber. | 05-14-2009 |
20090143723 | FLOW CONTROL DEVICE FOR PERITONEAL DIALYSIS - A peritoneal dialysis flow control device in one embodiment includes: (i) a first cap including a first medical fluid line connection and a second medical fluid line connection; (ii) a gasket mated with the first cap where the gasket defines a first aperture in fluid communication with a first port and a second aperture in fluid communication with a second port; and (iii) a second cap including a third medical fluid line connection where the second cap is sealed rotatably to the gasket. | 06-04-2009 |
20090275881 | OPTIMIZING THERAPY OUTCOMES FOR PERITONEAL DIALYSIS - Peritoneal dialysis therapy outcomes have been calculated for a variety of dwell times of peritoneal dialysis fluids in the peritoneal cavities of dialysis patients using kinetic modeling. The length of dwell time should not be the same for every patient, but should vary according to the patient condition and needs. Some patients have a potential for expressing greater ultrafiltrate into the dialysis fluid, and these patients can benefit from a longer dwell time, whereas other patients with less potential will not benefit from a longer dwell time. An optimal or peak time is observed for each peritoneal dialysis therapy outcome, such as ultrafiltrate volume rate, urea clearance (Kt/V), and creatinine clearance, while minimizing hydrocarbon absorption. These values and input parameters can be used to tailor the peritoneal dialysis dwell time for each patient, estimating the peak dwell time that will yield the best therapy outcome for each patient. | 11-05-2009 |
20090275883 | SMART PATIENT TRANSFER SET FOR PERITONEAL DIALYSIS - A peritoneal dialysis system includes: a dialysis fluid container associated with an identifier; a reader for reading the identifier; a signal transmitter for communicating data based on the identifier; and a patient transfer set for semi-permanent connection to a patient, the patient transfer set including: (i) a signal receiver for receiving the data sent by the signal transmitter, (ii) an output device for communicating with the patient, and (iii) electronics configured to received the data and command the output device to communicate with the patient accordingly. | 11-05-2009 |
20100004588 | NANOCLAY SORBENTS FOR DIALYSIS - Dialysis is enhanced by using nanoclay sorbents to better absorb body wastes in a flow-through system. Nanoclay sorbents, using montmorillonite, bentonite, and other clays, absorb significantly more ammonium, phosphate, and creatinine, and the like, than conventional sorbents. The clays may be used in wearable systems, such as a wearable peritoneal dialysis system, in which the dialysis fluid is circulated through a filter with nanoclay sorbents. Waste products are absorbed by the nanoclays and the dialysis fluid is recycled to the patient's peritoneum. Using the ion-exchange capability of the nanoclays, waste ions in the dialysis fluid are replaced with desirable ions, such as calcium, magnesium, and bicarbonate. The nanoclay sorbents are also useful for refreshing dialysis fluid used in hemodialysis and thus reducing the quantity of dialysis fluid needed for hemodialysis. | 01-07-2010 |
20100051552 | IN-LINE SENSORS FOR DIALYSIS APPLICATIONS - A system for monitoring water quality for dialysis, dialysis fluids, and body fluids treated by dialysis fluids, is disclosed. The system uses microelectromechanical systems (MEMS) sensors for detecting impurities in input water or dialysis fluid, and in the prepared dialysate. These sensors may also be used to monitor and check the blood of the patient being treated. These sensors include ion-selective sensors, for ions such as ammonium or calcium, and also include amperometric array sensors, suitable for ions from chlorine or chloramines, e.g., chloride. These sensors assist in the monitoring of water supplies from a city water main or well. The sensors may be used in conjunction with systems for preparing dialysate solutions from water for use at home or elsewhere. | 03-04-2010 |
20100191181 | DRAIN AND FILL LOGIC FOR AUTOMATED PERITONEAL DIALYSIS - A system and method for automatically adjusting a Continuous Cycling Peritoneal Dialysis (“CCPD”) therapy to minimize the potential for excess intra-peritoneal volume. The adjustments are made at the end of the drain, just prior to the next fill. The adjustments short the next fill, if necessary, to limit the intra-peritoneal volume, add a cycle, if necessary, to use all of the available dialysis solution and will average the remaining dwell time to maximize the therapeutic benefit of the therapy in the allotted time. In another embodiment, a tidal therapy using trended patient UF data is provided. | 07-29-2010 |
20100198138 | TRANSFER SETS FOR THERAPY OPTIMIZATION - Transfer sets are disclosed in the present patent. The transfer set provides a connection between a source of peritoneal dialysis fluid and a patient for whom peritoneal dialysis has been prescribed. The transfer sets disclosed herein are smaller and provide a more compact and convenient device by which a dialysis patient controls the flow of dialysis fluid to and from the peritoneum of the patient. The devices are more compact and convenient because they include more convenient mechanisms for starting and stopping flow of the dialysis fluid. It is also easy to determine whether the mechanism is in a closed or open configuration by simply looking at the mechanism. | 08-05-2010 |
20100217178 | PREDICTION OF PERITONEAL DIALYSIS THERAPY OUTCOMES USING DIALYSATES MIXED AT DIFFERENT GLUCOSE CONCENTRATIONS - A method for peritoneal dialysis treatment includes (i) predicting results of a plurality of patient therapy outcomes for a plurality of different mixed dextrose level dialysis solutions; (ii) selecting one of the mixed dextrose level solutions for a patient based on the results; and (iii) performing at least one therapy using different unmixed dextrose level solutions that combine to simulate a like cumulative concentration that would be achieved using the selected mixed dextrose level solution. | 08-26-2010 |
20100217179 | BULK DELIVERY PERITONEAL DIALYSIS SYSTEM AND METHOD - A peritoneal dialysis method includes (i) connecting smaller and larger supply containers to a junction, the smaller and larger supply bags both full of dialysate; (ii) allowing the junction to be connected to a patient's transfer set; allowing the patient to drain through the junction; (iii) allowing the patient to fill from the smaller supply container; and (iv) allowing the patient to refill the smaller supply container from the larger supply container. | 08-26-2010 |
20100217180 | SIMULATION OF PATIENT DRAIN PHASE IN PERITONEAL DIALYSIS - A method of modeling a patient's peritoneal dialysis drain phase includes (i) modeling a first segment of a drain phase curve as having a constant flowrate; (ii) modeling a second segment of a drain phase curve as having a decaying exponential flowrate; and (iii) incorporating a switching component into the first and second components so that (a) at a first time the first segment is active and while the second segment is inactive and (b) at a second time the first segment is inactive and while the second segment is active. | 08-26-2010 |
20110009810 | PERITONEAL DIALYSIS THERAPY WITH LARGE DIALYSIS SOLUTION VOLUMES - Patients suffering from acute renal failure must be diagnosed and treated quickly so that a physician can confidently prescribe either peritoneal dialysis or hemodialysis. In one way of quickly treating the patients, software is used to calculate a suitable peritoneal dialysis prescription without regard to how short or how long a dialysis cycle is used, and without regard to a total dialysate fluid volume for a therapy. For patients with suitable peritoneal membrane transport properties, the software program suggests that, at least over a short period of time, unexpectedly high ultrafiltrate volumes and high clearances may be achieved. | 01-13-2011 |
20110010101 | SIMPLIFIED PERITONEAL EQUILIBRATION TEST FOR PERITONEAL DIALYSIS - A simplified peritoneal equilibration test (S-PET) is disclosed. Instead of a lengthy peritoneal equilibration test (PET), the simplified procedure requires no blood sample and may use data from as few as two or three samples to classify a peritoneal membrane of a user. Typically, a peritoneal membrane or peritoneum of a dialysis patient, or other person, is classed as a high transport membrane, high-average transport membrane, a low-average transport membrane or a low transporter membrane. The S-PET may be performed at home by a user without the need to submit a blood sample. Kits for analyzing the samples may be furnished for home use. The kits may use disposable strips, microfluidic analyzers or chemical reagents, or may alternatively include reusable analysis equipment, such as optical or conductivity analysis equipment. | 01-13-2011 |
20110093294 | PERITONEAL DIALYSIS OPTIMIZED USING A PATIENT HAND-HELD SCANNING DEVICE - A dialysis system includes: a portable device configured to be carried by a patient and to read a marking displayed on a dialysis fluid container, the device obtaining data concerning at least one of a dialysis fluid type and a dialysis fluid volume from the marking; the device defined dialysate dwell time, alert patients for the next exchange and further configured to transfer the data to a computer; and wherein the computer is configured to use the data to track therapy progress of the product. | 04-21-2011 |
20110257891 | THERAPY PREDICTION AND OPTIMIZATION FOR RENAL FAILURE BLOOD THERAPY, ESPECIALLY HOME HEMODIALYSIS - A method of predicting serum phosphorus concentrations in a patient during hemodialysis includes measuring serum phosphorus concentrations of the patient over a hemodialysis treatment session time and an ultrafiltration rate calculated by a difference between pre- and post-dialytic body weight of the patient during an initial hemodialysis treatment session divided by a total treatment time of the treatment session and estimating a phosphorous mobilization clearance and a pre-dialysis distribution volume of phosphorus for the patient. Serum phosphorus concentrations of the patient can then be predicted at any time during any hemodialysis treatment session with the estimated phosphorous mobilization clearance and pre-dialysis distribution volume of phosphorus of the patient. | 10-20-2011 |
20110297598 | HEMODIALYSIS SYSTEM WITH SEPARATE DIALYSATE CASSETTE - A hemodialysis system includes (i) a dialyzer; (ii) a blood pump; (iii) a blood cassette operatively connected to the dialyzer and the blood pump; (iv) a dialysate heater; (v) first and second peristaltic dialysate pumps; and (vi) a dialysate cassette separate from the blood cassette, the dialysate cassette including an organizer configured to support a drain tube, a to-dialyzer tube and a from-dialyzer tube, the cassette further including a first pumping tube, a second pumping tube and an inline fluid heating pathway, the cassette when mounted for operation orienting (a) the first pumping tube for operation with the first peristaltic dialysate pump, (b) the second pumping tube for operation with the second peristaltic dialysate pump and (c) the fluid heating pathway for operation with the dialysate heater. | 12-08-2011 |
20110303598 | HEMODIALYSIS SYSTEM WITH SEPARATE BLOOD CASSETTE - A hemodialysis system includes: (i) a dialyzer; (ii) a dialysate source; a dialysate pump; (iii) a dialysate cassette operatively connected to the dialysate pump such that the dialysate pump can pump dialysate through the dialysate cassette when the dialysate cassette is in fluid communication with the dialysate source, the dialysate cassette in fluid communication with the dialyzer; (iv) a blood pump; and (v) a blood cassette separate from the dialysate cassette, the blood cassette operatively connected to the blood pump such that the blood pump can pump blood through the blood cassette, the blood cassette including a housing, the housing including a from-patient tube connector, a to-patient tube connector, a saline/priming tube connector, a to-dialyzer tube connector, a from-dialyzer tube connector, and an internal air separation chamber. | 12-15-2011 |
20120029324 | THERAPY PREDICTION AND OPTIMIZATION FOR RENAL FAILURE BLOOD THERAPY, ESPECIALLY HOME HEMODIALYSIS - A method of predicting serum phosphorus concentrations in a patient during hemodialysis includes measuring serum phosphorus concentrations of the patient over a hemodialysis treatment session time and an ultrafiltration rate calculated by a difference between pre- and post-dialytic body weight of the patient during an initial hemodialysis treatment session divided by a total treatment time of the treatment session and estimating a phosphorous mobilization clearance and a pre-dialysis distribution volume of phosphorus for the patient. Serum phosphorus concentrations of the patient can then be predicted at any time during any hemodialysis treatment session with the estimated phosphorous mobilization clearance and pre-dialysis distribution volume of phosphorus of the patient. | 02-02-2012 |
20120071815 | DRAIN AND FILL LOGIC FOR AUTOMATED PERITONEAL DIALYSIS - The present system and method in one embodiment limit a maximum instantaneous peritoneal volume to a comfortable level, while allowing the dialysis machine to advance to fill a prescribed volume whenever the drain ends after a minimum drain percentage has been attained. If a low drain condition occurs, the nominal fill volume is lowered and a therapy cycle is added, so that a prescribed total amount of fresh therapy fluid is used during therapy, maximizing therapeutic benefit. An allowable residual volume at the end of an incomplete drain is increased, thereby lowering the probability of a subsequent low drain condition. | 03-22-2012 |
20120215159 | DRAIN AND FILL LOGIC FOR AUTOMATED PERITONEAL DIALYSIS - A system and method for automatically adjusting a Continuous Cycling Peritoneal Dialysis (“CCPD”) therapy to minimize the potential for excess intra-peritoneal volume. The adjustments are made at the end of the drain, just prior to the next fill. The adjustments short the next fill, if necessary, to limit the intra-peritoneal volume, add a cycle, if necessary, to use all of the available dialysis solution and will average the remaining dwell time to maximize the therapeutic benefit of the therapy in the allotted time. In another embodiment, a tidal therapy using trended patient UF data is provided. | 08-23-2012 |
20130030356 | SODIUM MANAGEMENT FOR DIALYSIS SYSTEMS - Systems and methods for providing dialysis therapies are provided. In a general embodiment, the present disclosure provides an apparatus for dialysis treatment comprising first and second fluid flow pathways in a parallel arrangement. The first fluid flow pathway contains a first cation exchange resin, wherein greater than 90% of exchange sites of the first cation exchange resin are populated with hydrogen ions. The second fluid flow pathway contains a second cation exchange resin, wherein greater than 90% of exchange sites of the second cation exchange resin are populated with sodium ions. The apparatus can be used to maintain a constant and safe level of sodium in a constantly regenerated dialysis fluid over an extended period of time. | 01-31-2013 |
20130131583 | TRANSFER SETS FOR THERAPY OPTIMIZATION - Transfer sets are disclosed in the present patent. The transfer set provides a connection between a source of peritoneal dialysis fluid and a patient for whom peritoneal dialysis has been prescribed. The transfer sets disclosed herein are smaller and provide a more compact and convenient device by which a dialysis patient controls the flow of dialysis fluid to and from the peritoneum of the patient. The devices are more compact and convenient because they include more convenient mechanisms for starting and stopping flow of the dialysis fluid. It is also easy to determine whether the mechanism is in a closed or open configuration by simply looking at the mechanism. | 05-23-2013 |
20130193073 | BALANCED FLOW DIALYSIS MACHINE - A system and method for balancing flows of renal replacement fluid is disclosed. The method uses pressure controls and pressure sensing devices to more precisely meter and balance the flow of fresh dialysate and spent dialysate. The balancing system may use one or two balancing devices, such as a balance tube, a tortuous path, or a balance chamber. | 08-01-2013 |
20130317795 | SIMULATION OF PATIENT DRAIN PHASE IN PERITONEAL DIALYSIS - A method of modeling a patient's peritoneal dialysis drain phase includes (a) modeling a first segment of a drain phase curve as having a constant flowrate, (b) modeling a second segment of the drain phase curve as having a decaying exponential flowrate, and (c) ensuring that a drain flowrate does not fall below a certain level during therapy by incorporating a switching component so that (i) at a first time the first segment is active while the second segment is inactive and (ii) at a second time the first segment is inactive while the second segment is active. | 11-28-2013 |
20150021268 | HEMODIALYSIS AND PERITONEAL DIALYSIS SYSTEMS HAVING ELECTRODEIONIZATION CAPABILITIES - Systems and methods for hemodialysis or peritoneal dialysis having integrated electrodeionization capabilities are provided. In an embodiment, the dialysis system includes a carbon source, a urease source and an electrodeionization unit. The carbon source and urease source can be in the form of removable cartridges. | 01-22-2015 |
20150032043 | THERAPY PREDICTION AND OPTIMIZATION FOR RENAL FAILURE BLOOD THERAPY, ESPECIALLY HOME HEMODIALYSIS - A renal failure blood therapy system includes a renal failure blood therapy machine, a test including multiple blood samples taken at multiple times during a test therapy to determine concentration levels for each of a first solute and a second solute at each of the multiple times, and a device programmed to (i) estimate at least one first patient parameter using the determined concentration levels for the first solute, (ii) estimate at least one second patient parameter using the determined concentration levels for the second solute, (iii) determine a first plurality of acceptable treatments using the at least one first patient parameter, (iv) determine a second plurality of acceptable treatments using the at least one second patient parameter, and (v) merge the first plurality of acceptable treatments with the second plurality of acceptable treatments to determine a plurality of clinically acceptable treatments for both the first solute and the second solute. | 01-29-2015 |