Patent application number | Description | Published |
20130210906 | COMPOUNDS, METHODS OF PREPARATION AND USE THEREOF FOR TREATING CANCER - The present invention provides two compounds, namely Compound A and B, as the potential anticancer drug, and a composition comprising said Compound A and/or B for treating cancer or tumor related diseases. The present invention also relates to methods of preparing the compounds from a natural source and a composition comprising the compounds, and using the same for treating cancer or tumor related diseases. | 08-15-2013 |
20130210907 | METHOD FOR PREVENTING OR TREATING ENTEROCHROMAFFIN CELL HYPERPLASIA-RELATED DISEASES BY QUERCETIN ADMINISTRATION - The present invention provides methods and compositions for preventing or treating enterochromatffin cell hyperplasia-related diseases. The compositions comprise a therapeutic effective amount of Quercetin, glycosylated Quercetin, or mixture thereof. The methods comprises administering said composition as well as preparing said composition as a pharmaceutical formulation, | 08-15-2013 |
20130323329 | Method Of Using Rhein For Treating Fibrotic Conditions And Tumors - The present invention relates to a method of using an anthraquinone derivative namely 9,10-Dihyro-4,5-dihydroxy-9,10-dioxo-2-anthracenecarboxylic acid, or known as Rhein, for treating chronic pancreatitis induced fibrosis of the pancreas. More particularly, the present invention relates to a method of using Rhein, its derivatives and/or chemical variants as an anti-fibrotic agent. The present invention particularly relates to the suppression of pancreatic stellate cell activation for the management of chronic inflammatory, fibrotic and tumorigenic pathologies in the pancreas. | 12-05-2013 |
20130344174 | Bioactive Fractions and Compounds from Polygonum genus, their Use in Anti-diarrhea and the Method of Preparation - The present invention discloses the utility of factions and compounds from | 12-26-2013 |
20140194498 | POLYISOPRENYLATED TETRACYCLIC XANTHONE WITH ANTICANCER ACTIVITY - A novel polyisoprenylated tetracyclic xanthone, named garciesculentone B, isolated from | 07-10-2014 |
20140194528 | USAGE OF SODIUM HOUTTUYFONATE ON INHIBITING IDIOPATHIC PULMONARY FIBROSIS AND BLEOMYCIN INDUCED PULMONARY FIBROSIS - The present invention relates to a synthetic compound and its therapeutic uses. More particularly, it relates to a compound, Sodium Houttuyfonate, that is an addition compound of sodium bisulfite and houttuynin, and its biological activity of inhibiting idiopathic pulmonary fibrosis and bleomycin induced pulmonary fibrosis | 07-10-2014 |
20140194530 | USAGE OF OBLONGIFOLIN C, A NATURAL COMPOUND FROM GARCINIA YUNNANENSIS HU, ON TREATING CANCER AS METASTASIS INHIBITOR AND AUTOPHAGIC FLUX INHIBITOR - Disclosed is a natural compound, Oblongifolin C, isolated from a natural plant comprising | 07-10-2014 |
20140200265 | USAGE OF 1,3,5,7-TETRAHYDROXY-8-ISOPRENYLXANTHONE FOR TREATING INFLAMMATION - This invention relates to the use of a natural compound from natural sources for its therapeutic uses. More particularly, it relates to a compound 1,3,5,7-tetrahydroxy-8-isoprenylxanthone (TI, FIG. | 07-17-2014 |
20140235877 | COMPOUNDS, METHODS OF PREPARATION AND USE THEREOF FOR TREATING CANCER - The present invention provides two compounds, namely Compound A and B, as the potential anticancer drug, and a composition comprising said Compound A and/or B for treating cancer or tumor related diseases. The present invention also relates to methods of preparing the compounds from a natural source and a composition comprising the compounds, and using the same for treating cancer or tumor related diseases. | 08-21-2014 |
20150025155 | ANTI-PROSTATE CANCER COMPOUND AND METHOD OF USE THEREOF - Prostate cancer is the most commonly diagnosed cancer in males and one of the leading causes of cancer death. Although treatment options have increased for some patients, overall progress has been modest. Thus, there is a great need to develop new treatments. This invention relates to a method for treating cancer comprising using an anti-cancer compound. More particularly, it relates to an anti-prostate cancer compound that can be isolated from | 01-22-2015 |
20150366841 | Pd-Ib for Treating Inflammation - The present invention provides a compound, namely (+)-3′-Angeloyloxy-4′-keto-3′, 4′-dihydroseselin (Pd-Ib) derived from | 12-24-2015 |
Patent application number | Description | Published |
20090247503 | 5-DEMETHOXYFUMAGILLOL AND DERIVATIVES THEREOF - Provided herein are 5-demethoxyfumagillol and its derivatives. Also provided herein are methods of making the 5-demethoxyfumagillol and derivatives. Also provided herein are biological activities of the 5-demethoxyfumagillol and derivatives and methods of using same for treating diseases. | 10-01-2009 |
20090253118 | LUMINESCENCE QUENCHERS AND FLUOROGENIC PROBES FOR DETECTION OF REACTIVE SPECIES - Provided herein are compounds or fluorogenic probes which can be used as reagents for measuring, detecting and/or screening ROS or RNS such as peroxynitrite or hypochlorite. Provided also herein are methods that can be used to measure, directly or indirectly, the amount of peroxynitrite or hypochlorite in chemical samples and biological samples such as cells and tissues in living organisms. Specifically, the methods include the steps of contacting the fluorogenic probes disclosed herein with the samples to form one or more fluorescent compounds, and measuring fluorescence properties of the fluorescent compounds. Provided also herein are high-throughput screening fluorescent methods for detecting or screening peroxynitrite or compounds that can increase or decrease the level of peroxynitrite or hypochlorite in chemical and biological samples. | 10-08-2009 |
20090253143 | FLUOROPHORE COMPOUNDS - Provided herein are fluorophore compounds including rhodol and rhodamine compounds which can be used as fluorescent labels and/or fluorogenic probes and methods of making same. Provided also herein are methods that can be used to track, measure, detect, or screen biological species such as protein, DNA, enzyme, antibody, organelle, cell, tissue, drug, hormone, nucleotide, nucleic acid, polysaccharide or lipid in living organisms. Specifically, the methods include the steps of contacting any of the fluorophore compounds, rhodol compounds and rhodamine compounds disclosed herein with the biological species to form one or more fluorescent compounds, and measuring fluorescence properties of the fluorescent compounds. Provided also herein are high-throughput screening fluorescent methods for detecting or screening biological species. | 10-08-2009 |
20110221018 | Electronic Device Package and Methods of Manufacturing an Electronic Device Package - An electronic device package comprises a substrate | 09-15-2011 |
20120187462 | HIGH OPTICAL EFFICIENCY CMOS IMAGE SENSOR - High optical efficiency CMOS image sensors capable of sustaining pixel sizes less than 1.2 microns are provided. Due to high photodiode fill factors and efficient optical isolation, microlenses are unnecessary. Each sensor includes plural imaging pixels having a photodiode structure on a semiconductor substrate adjacent a light-incident upper surface of the image sensor. An optical isolation grid surrounds each photodiode structure and defines the pixel boundary. The optical isolation grid extends to a depth of at least the thickness of the photodiode structure and prevents incident light from penetrating through the incident pixel to an adjacent pixel. A positive diffusion plug vertically extends through a portion of the photodiode structure. A negative diffusion plug vertically extends into the semiconductor substrate for transferring charge generated in the photodiode to a charge collecting region within the semiconductor substrate. Pixel circuitry positioned beneath the photodiode controls charge transfer to image readout circuitry. | 07-26-2012 |
20130187267 | INCREASED SURFACE AREA ELECTRICAL CONTACTS FOR MICROELECTRONIC PACKAGES - A multilayer microelectronic device package includes one or more vertical electrical contacts. At least one semiconductor material layer is provided having one or more electrical devices fabricated therein. An electrical contact pad can be formed on or in the semiconductor material layer. Another material layer is positioned adjacent to the semiconductor material layer and includes a conductive material stud embedded in or bonded to the layer. A via is formed through at least a portion of the semiconductor material layer and the electrical contact pad and into the adjacent layer conducting material stud. The via is constructed such that the via tip terminates within the conducting material stud, exposing the conducting material. A metallization layer is disposed in the via such that the metallization layer contacts both the electrical contact pad and the conducting material stud exposed by the via tip. | 07-25-2013 |
20130292787 | LOW COST BACKSIDE ILLUMINATED CMOS IMAGE SENSOR PACKAGE WITH HIGH INTEGRATION - This invention discloses a backside illuminated image sensor without the need to involve a mechanical grinding process or a chemical-mechanical planarization process in fabrication, and a fabricating method thereof. In one embodiment, an image sensor comprises a semiconductor substrate, a plurality of light sensing elements in the semiconductor substrate, and a cavity formed in the semiconductor substrate. The light sensing elements are arranged in a substantially planar manner. The cavity has a base surface overlying the light sensing elements. The presence of the cavity allows the image to reach the light sensing elements through the cavity base surface. The cavity can be fabricated by etching the semiconductor substrate. Agitation may also be used when carrying out the etching. | 11-07-2013 |
20140021596 | WAFER-LEVEL DEVICE PACKAGING - The present invention relates to a semiconductor device packaged at the wafer level such that an entire packaged device is formed prior to separation of individual devices. The semiconductor device package includes a semiconductor chip having one or more bonding pads associated with the chip and a protective layer bonded over the semiconductor chip. An insulation layer is positioned on at least side edges and a lower surface of the semiconductor chip. Interconnection/bump metallization is positioned adjacent one or more side edges of the semiconductor chip and is electrically connected to at least one bonding pad. A compact image sensor package can be formed that is vertically integrated with a digital signal processor and memory chip along with lenses and a protective cover. | 01-23-2014 |
20140131882 | THROUGH-SILICON VIA STRUCTURE WITH PATTERNED SURFACE, PATTERNED SIDEWALL AND LOCAL ISOLATION - This invention discloses a through-silicon via (TSV) structure for providing an electrical path between a first-side surface and a second-side surface of a silicon chip, and a method for fabricating the structure. In one embodiment, the TSV structure comprises a via penetrated through the chip from the first-side surface to the second-side surface, providing a first end on the first-side surface and a second end on the second-side surface. A local isolation layer is deposited on the via's sidewall and on a portion of the first-side surface surrounding the first end. The TSV structure further comprises a plurality of substantially closely-packed microstructures arranged to form a substantially non-random pattern and fabricated on at least the portion of the first-side surface covered by the local isolation layer for promoting adhesion of the local isolation layer to the chip. A majority of the microstructures has a depth of at least 1 μm. | 05-15-2014 |
20150016078 | Partitioned Hybrid Substrate for Radio Frequency Applications - The presently claimed invention is to provide a package for compact RF signal system, and a method to form the package thereof in order to miniaturize the size of package, improve signal integrity, and reduce manufacturing cost. The package comprises a hybrid substrate with a sandwiched structure, in which the hybrid substrate comprises an upper layer and a lower layer with different dielectric properties being separated by an interposer for improving electrical isolation and mechanical stiffness. Metal layers are formed on the sidewalls of the opening to surround an active component, such that the metal sidewalls together with two ground plates in the upper and lower layers constitute a self-shielding enclosure inside the package to protect the active component. | 01-15-2015 |
Patent application number | Description | Published |
20080274560 | REAGENTS FOR DETECTION OF HYPOCHLOROUS ACID - Provided herein are compounds or hypochlorous acid probes which can be used as reagents for measuring, detecting and/or screening, directly or indirectly, hypochlorous acid or hypochlorite. Provided also herein are methods that can be used to measure, directly or indirectly, the amount of hypochlorous acid or hypochlorite in chemical samples and biological samples such as cells and tissues in living organisms. Specifically, the methods include the steps of contacting the hypochlorous acid probes disclosed herein with the samples to form one or more fluorescent compounds, and measuring fluorescence properties of the fluorescent compounds. Provided also herein are high-throughput screening fluorescent methods for detecting or screening hypochlorous acid or compounds that can increase or decrease, directly or indirectly, the level of hypochlorous acid or hypochlorite in chemical and biological samples. | 11-06-2008 |
20090163595 | Method of Modulating Membrane Potential of a Cell - Provided herein are methods of modulating membrane potential of a cell membrane using self-assembling compounds. Also provided herein are methods of regulating a natural voltage-dependent ion channel in a cell membrane using the self-assembling compounds disclosed herein. Further provided herein are methods of treating, preventing and/or managing a disease that is related to the abnormal membrane potential responses by using the self-assembling compounds disclosed herein. | 06-25-2009 |
20110212975 | ANTIVIRAL COMPOUNDS AND METHODS OF MAKING AND USING THEREOF - Compounds which exhibit antiviral activity, particularly against influenza virus, and methods of making and using thereof are described herein. In one embodiment, the compounds are heterocyclic amides containing piperazine and isozazole rings and optionally substituted with one or more substituents. The compounds can be formulated with one or more pharmaceutically acceptable excipients to form compositions suitable for enteral or parenteral administration. The compounds are preferably used to treat or prevent Influenza A infections, such as H1N1, H2N2, H3N2, H5N1, H7N7, H1N2, H9N2, H7N2, H7N3, and H10N7. | 09-01-2011 |
20120149715 | COMPOUNDS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS - High throughput and virtual screening methods are disclosed that can identify potential anti-viral agents. The virtual screening methods identify agents that interact with a viral nucleoprotein binding site. The high throughput methods identify compounds that inhibit viral infection by binding to viral nucleoprotein. Also disclosed are pharmaceutical formulations useful for treating or preventing viral infections, especially influenza A. | 06-14-2012 |
20130196362 | DIARYLAMINE-BASED FLUOROGENIC PROBES FOR DETECTION OF PEROXYNITRITE - Provided herein are improved fluorogenic compounds and probes that can be used as reagents for measuring, detecting and/or screening peroxynitrite. The fluorogenic compounds of the invention can produce fluorescence colors, such as green, yellow, red, or far-red. Also provided herein are fluorogenic compounds for selectively staining peroxynitrite in the mitochondria of living cells. Provided also herein are methods that can be used to measure, directly or indirectly, the presence and/or amount of peroxynitrite in chemical samples and biological samples such as cells and tissues in living organisms. Also provided are high-throughput screening methods for detecting or screening peroxynitrite or compounds that can increase or decrease the level of peroxynitrite in chemical and biological samples. | 08-01-2013 |
20130244944 | Synthetic Ion Channels - Provided herein are self-assembling compounds that can form ion channels in lipid bilayers or cell membranes and ion-channel-forming compositions comprising the self-assembling compounds. Also provided are methods of making and using the ion channels formed from a plurality of molecules of the self-assembling compounds. Further, provided are methods of treating or preventing conditions and diseases that are related to the dysfunction of ion channels, including chloride channels. | 09-19-2013 |
20130325429 | Compounds and Methods for the Treatment of Viral Infections - High throughput and virtual screening methods are disclosed that can identify potential anti-viral agents. The virtual screening methods identify agents that interact with a viral nucleoprotein binding site. The high throughput methods identify compounds that inhibit viral infection by binding to viral nucleoprotein. Also disclosed are pharmaceutical formulations useful for treating or preventing viral infections, especially influenza A. | 12-05-2013 |
20140155478 | ANTIFUNGAL COMPOUND AND USES THEREOF - Disclosed herein is a novel antifungal compound, derivatives that are used to treat fungal infections. In a specific embodiment, the compound is a small molecule. In a specific embodiment, the compound described herein inhibits yeast to hypha transition under robust hyphal inducing conditions at lower concentration of the molecule. Also disclosed is a composition comprising the antifungal compound. In a specific embodiment, the composition is a pharmaceutical composition. Also disclosed is a method of treating and/or preventing fungal infection using the disclosed compound. The disclosed compound exhibits antifungal activity against wide range of fungal species at slightly higher concentrations. Antifungal compound disclosed herein is used as anti-biofilm agent against fungal infections. | 06-05-2014 |
20150219676 | BISTRIFILATE-BASED FLUOROGENIC PROBES FOR DETECTION OF SUPEROXIDE ANION RADICAL - The invention provides fluorogenic compounds and probes that can be used as reagents for measuring, detecting and/or screening superoxide. The fluorogenic compounds of the invention can produce fluorescence colors, such as green, yellow, red, or far-red. The invention further provides fluorogenic compounds for selectively staining superoxide in the mitochondria of living cells. The invention also provides methods that can be used to measure, directly or indirectly, the presence and/or amount of superoxide in chemical samples and biological samples such as cells and tissues in living organisms, and a high-throughput screening methods for detecting or screening superoxide or compounds that can increase or decrease the level of superoxide in chemical and biological samples. | 08-06-2015 |
Patent application number | Description | Published |
20100184856 | Novel Compounds and Uses Thereof for Treating Inflammation and Modulating Immune Responses - The present invention provides compounds, and compositions comprising these compounds, which have immunomodulatory activity and/or anti-inflammatory activity. | 07-22-2010 |
20110177106 | Novel Therapeutic Methods for Treating Inflammation and Immune System Disorders - The subject invention provides novel and advantageous materials and methods for treating neuroinflammation, neurodegenerative disease, and cerebrovascular disease by modulating TNF-α and/or nitric oxide production. Specifically exemplified herein is the therapeutic use of senkyunolide A (Sen A) and Z-ligustilide (Z-Lig), compounds isolated from traditional Chinese medicinal material | 07-21-2011 |
20120190882 | EFFICIENT ISOLATION OF CIMIRACEMATE A, AND METHODS OF USE - A method for isolating cimiracemate A from a | 07-26-2012 |
20130029923 | Materials and Methods for Prevention and Treatment of Viral Infections - The subject invention provides a novel and advantageous method for preventing and treating viral infection. Specifically exemplified herein are therapeutic uses of forsythoside A and jacaranone, compounds isolated from traditional Chinese medicinal material such as | 01-31-2013 |
20130237599 | COMPOUNDS AND USES THEREOF FOR TREATING INFLAMMATION AND MODULATING IMMUNE RESPONSES - The present invention provides compounds, and compositions comprising these compounds, which have immunomodulatory activity and/or anti-inflammatory activity. | 09-12-2013 |
20130274333 | CORIOLUS VERSICOLOR EXTRACTS, METHODS OF ISOLATING BIOLOGICALLY-ACTIVE COMPOUNDS, AND USES THEREOF - The subject invention provides efficient and convenient methods of isolating 9-oxo-10E, 12E-octadecadienoic acid methyl ester (9-KODE methyl ester) from | 10-17-2013 |
20130281393 | MATERIALS AND METHODS FOR PREVENTION AND TREATMENT OF VIRAL INFECTIONS - The present invention provides novel and advantageous materials and methods for preventing and treating viral infection. | 10-24-2013 |
20140255450 | NOVEL COMPOUNDS AND USES THEREOF FOR TREATING INFLAMMATION AND MODULATING IMMUNE RESPONSES - The present invention provides compounds, and compositions comprising these compounds, which have immunomodulatory activity and/or anti-inflammatory activity. | 09-11-2014 |
20140364499 | CORIOLUS VERSICOLOR EXTRACTS, METHODS OF ISOLATING BIOLOGICALLY-ACTIVE COMPOUNDS, AND USES THEREOF - The subject invention provides efficient and convenient methods of isolating 9-oxo-10E, 12E-octadecadienoic acid methyl ester (9-KODE methyl ester) from | 12-11-2014 |
Patent application number | Description | Published |
20130074913 | BILAYER DYE SENSITIZED SOLAR CELL AND FABRICATION METHOD THEREOF - A photovoltaic cell comprises a first electrode that includes a first transparent conductive substrate, a first layer having a plurality of first semiconductor nanofibers, and a second layer having a plurality of second semiconductor super-fine fibers, the first semiconductor nanofibers having an average diameter smaller than an average diameter of the second semiconductor super-fine fibers, a light absorbing material adsorbed to at least some of the first semiconductor nanofibers and second semiconductor super-fine fibers, a second electrode includes a second transparent conductive substrate, and electrolytes dispersed in the first and second layers. | 03-28-2013 |
20130298981 | DYE-SENSITIZED SOLAR CELL BASED ON INDIRECT CHARGE TRANSFER - A dye-sensitized solar cell that includes an electrode having a semiconductor nanoparticle layer dispersed on a transparent conductive substrate, a plurality of semiconductor nanofibers dispersed on the nanoparticle layer, a first light absorption material is attached to the plurality of semiconductor nanofibers in which the first light absorption material having a first light absorption bandwidth, and a second light absorption material deposited on the light absorption material of the plurality of semiconductor nanofibers, the second light absorption material having a second light absorption bandwidth complementary to the first light absorption bandwidth, a counter electrode includes a metal-coated transparent conductive substrate, and an electrolyte in contact with the near-infrared light absorption material and the counter electrode. | 11-14-2013 |
20140158986 | Highly Conductive Nano-structures incorporated in Semiconductor Nanocomposites - The presently claimed invention provides a highly conductive composite used for electric charge transport, and a method for fabricating said composite. The composite comprises a plurality of one-dimensional semiconductor nanocomposites and highly conductive nanostructures, and the highly conductive nanostructures are incorporated into each of the one-dimensional semiconductor nanocomposite. The composite is able to provide fast electric charge transport, and reduce the rate of electron-hole recombination, ultimately increasing the power conversion efficiency for use in solar cell; provide fast electrons transport, storage of electrons and large surface area for adsorption and reaction sites of active molecular species taking part in photocatalytic reaction; enhance the sensitivity of a surface for biological and chemical sensing purposes for use in biological and chemical sensors; and lower the impedance and increase the charge storage capacity of a lithium-ion battery. | 06-12-2014 |
20150287852 | Crystal Control and Stability for High-Performance Perovskite Solar Cell | 10-08-2015 |
Patent application number | Description | Published |
20150076296 | INVERSELY FOLDABLE CAMERA TRIPOD BEING RAPIDLY ASSEMBLED - An inversely foldable camera tripod being rapidly assembled, comprising legs assemblies being rapidly assembled and being retracted by one-switch, a main body assembly capable of controlling the legs assemblies to rotate 180° around a shaft by one-switch, a central shaft assembly supporting a tripod head or a camera, and a tripod head assembly assembled with the tripod; the tripod is provided with legs being rapidly assembled; and the assembly and retraction of the legs are controlled by a simple-to-operate switch. The tripod can be inversely folded by 180° under the control of the switch, thus reducing the length of the tripod. When the tripod is positioned non-horizontally due to the factor of environment, an adjustable tripods head sphere can stay level during turning, so that the camera installed on the turntable is ensured to be horizontal and can rotate 360° horizontally via operating a locking device. | 03-19-2015 |
20150359114 | PORTABLE CLAMPING APPARATUS FOR MOBILE EQUIPMENT - A portable clamping apparatus for mobile equipment, which comprises a clamping assembly, a holding assembly and a tube-pole assembly used to connect other assembly, the holding assembly is configured on the bottom of the tube-pole assembly to secure others assembly, wherein the clamping assembly comprises a main body configured with a lower fixing end on its lower position, and a moveable mechanism configured on the main body, comprising several connecting rods and elastic parts used to reset the connecting rods; an upper end of the connecting rods is provided with an upper fixing end corresponding to the lower fixing end; the tube-pole assembly is connected to the clamping assembly by means of a platform assembly comprising a platform base, connecting brackets hinged to the platform base and an adjusting mechanism used to establish connection with clamping assembly and adjust the connecting rods to slide upwardly or downwardly is provided. | 12-10-2015 |