Yan, MA
Aiguo Yan, Andover, MA US
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20090161745 | Parameter Estimation for Modulated Signals - A system includes a receiver for receiving a modulated signal. The receiver includes a gain estimator for converting complex data representative of constellation points of the modulated signal into scalar data representation. The gain estimator is configured to fold a first portion of the scalar data representation onto a second portion of the scalar data representation. The gain estimator is further configured to estimate a constellation gain value from the folded first portion and the second portion of the scalar data representation. | 06-25-2009 |
20090165019 | Data Flow Control - A method includes receiving data in a first data processing module, and enabling a second data processing module when at least one signal time slot of the received data comprises data that complies with a first data transmission standard. The method also includes exchanging signals between the first data processing module and software executing in a processor, and determining that a software configuration of the second data processing module has been completed. The method also includes processing the data in the second data processing module for the at least one signal time slot, and enabling a third data processing module upon a completion of processing at least one data block in the second data processing module, and determining that a software configuration of the third data processing module has been completed, the at least one data block comprising multiple signal time slots. | 06-25-2009 |
20090175205 | Multi-mode Bit Rate Processor - An apparatus for processing signals in a wireless system includes a first memory module to receive input data from a set of physical channels, a first plurality of sub-modules to process the input data. Each of the first plurality of sub-modules is selected to function based upon data and transmission channel specifications. The apparatus also includes a second memory module to receive processed input data and output intermediate data. Locations of the input data in the second memory is allocated in connection with data and transmission channel specifications. The apparatus also includes a second plurality of sub-modules to process the intermediate data. Each of the second plurality of sub-modules is selected to function based upon data and transmission channel specifications. The apparatus also includes a third memory module to receive and output bit rate processing output. | 07-09-2009 |
20090304121 | RECEIVER ARCHITECTURE - A wireless receiver uses a joint detection Viterbi (JDV) algorithm to demodulate a signal that has a desired signal component and an interference signal component. The desired signal component includes a training sequence and at least one data field. The training sequence and a corresponding portion of the interference signal component is demodulated using the JDV algorithm to evaluate possible transmitted training sequences and interference signal sequences, and channel estimations for the desired signal component and the interference signal component are generated. The at least one data field is demodulated according to the JDV algorithm using the channel estimations as initial channel estimates for the JDV algorithm. | 12-10-2009 |
20090304122 | RECEIVER ARCHITECTURE - A receiver adaptively selects between a joint detection Viterbi demodulator and a second Viterbi demodulator to demodulate a received signal based on at least one characteristic of the received signal. The joint detection Viterbi demodulator jointly demodulates a desired signal component and an interference signal component of the received signal, and the second Viterbi demodulator demodulates the desired signal component without demodulating the interference signal component. | 12-10-2009 |
20120257548 | ACTIVE CODE SELECTION FOR JOINT-DETECTION BASED TDSCDMA RECEIVER - A TD-SCDMA receiver includes a joint detector that receives an input signal from a transceiver. The joint detector analyzes the input signal to using an active code selection (ACS) to determine whether one or more neighboring cells are used in conjunction with a servicing cell. Also, the ACS assigns a first matrix that includes necessary active coded channels including those associated with the one or neighboring cells so as to formulate a channel matrix. | 10-11-2012 |
20120269175 | EFFICIENT IMPLEMENTATION OF JOINT DETECTION BASED TDSCDMA RECEIVERS - A TD-SCDMA receiver includes a joint detector that receives an input signal from a transceiver. The joint detector analyzes the input signal to determine whether one or more neighboring cells are used in conjunction with a servicing cell. Also, the joint detector assigns a first matrix that includes all coded channels including those associated with the one or neighboring cells so as to formulate a channel matrix. The joint detector uses a selective ratio that has been minimized to define elements of the first matrix so as to efficiently control the bit-width of the joint detector. | 10-25-2012 |
20120269202 | TECHNIQUE FOR SWITCHING BETWEEN 1X AND 2X OVERSAMPLING RATE IN A TD-SCDMA RECEIVER - A TD-SCDMA receiver is provided that includes a joint detection (JD) block receiving a first input signal from a channel estimation block for signal detection. A short channel detection (SCD) block receives the first input signal and detecting the presence/absence of an AGWN-like channel based on the first input signal from the channel estimation block. The SCD block switches the JD block between 1× and 2× oversampling rates by sending to the JD block a second input signal. | 10-25-2012 |
20120275472 | CHANNEL IMPULSE RESPONSE (CIR)/DC OFFSET (DCO) JOINT ESTIMATION BLOCK AND METHOD - A channel impulse response (CIR)/DC offset (DCO) joint estimation for a time division synchronous code division multiple access (TDSCDMA) system includes generating from a basic midamble and received midamble an initial estimation of the CIR as a series of CIR taps; storing the initially estimated CIR taps; calculating a DC compensated CIR from the initially estimated CIR taps; filtering out the noise from the DC compensated CIR to produce the CIR estimation; and calculating the DC offset estimation from the CIR estimation. | 11-01-2012 |
20130070833 | ADVANCED JOINT DETECTION IN A TD-SCDMA SYSTEM - A communication system is provided that includes a composite transfer module that receives an input signal and performs one or more selective operations defined by a first transfer function on the input signal. The composite transfer module outputs a first signal. A joint detection module receives the first signal and performs joint detection on the first signal. The joint detection module utilizes channel estimation information of the first transfer function so as to allow the joint detection module to perform joint detection with an oversampling rate of 2× or higher. | 03-21-2013 |
20130094476 | METHOD AND SYSTEM FOR BLIND CHANNEL IMPULSE RESPONSE COMBINING FOR NOISE MITIGATION IN CHANNEL ESTIMATION IN A TD-SCDMA RECEIVER - Blind channel impulse response combining for noise mitigation in channel estimation in a TD-SCDMA receiver includes applying a correlation function to pairs of channel impulse response windows associated with non-desired user equipments, grouping all those channel impulse response windows having a correlation function above a predetermined threshold as identified with the same user equipment, and combining the channel estimation results from each identified user equipment in the group to mitigate noise. | 04-18-2013 |
Aiguo Yan, North Andover, MA US
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20090081973 | Multi-slot power control for wireless transmission - Methods and apparatus are provided for controlling transmitted power in a wireless system. The method includes generating information to be transmitted as a series of signal bursts, with a time interval between successive signal bursts, controlling individually a power level of each of said signal bursts with a power control signal to provide output signal bursts to be transmitted, and asserting a new power value of the power control signal during the time interval preceding each signal burst. The wireless system can be a TDSCDMA wireless system, and the signal bursts can be uplink signal bursts. | 03-26-2009 |
Anlu Yan, Acton, MA US
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20090132694 | BANDWIDTH CONSTRAINT CONSTRUCTION FOR OVERLAPPED LOGICAL CHANNELS - In one embodiment, a technique determines whether configured logical bandwidth allotments for logical channels are supported by maximum available physical bandwidths of physical channels assigned to those logical channels. The technique establishes a bandwidth-constraint directed acyclic graph (DAG) or “BCD” based on novel relationship rules between vertexes of the BCD that represent logical channels or unions of logical channels as well as the underlying physical channels and their maximum available bandwidth constraints. Once the BCD is established, the vertexes of the BCD may be traversed (e.g., from in-neighbor vertexes to out-neighbor vertexes) to determine whether their constraints are met. | 05-21-2009 |
Dengzhu Yan, Marlborough, MA US
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20140364873 | CAP WITH BAND DEPLOYMENT FEATURES - According to an embodiment of the present disclosure, a medical device for deploying a ligation band may include a tubular body. The tubular body may include a proximal end, a distal end, a radially inner surface defining a lumen through the tubular body, and a radially outer surface. The radially outer surface may include protrusions arranged in rows extending at least partially around a proximal region of the radially outer surface. Protrusions in adjacent rows may be separated by a first distance. Surface features may extend at least partially around a distal region of the radially outer surface. Adjacent surface features may be separated by a second distance larger than the first distance. | 12-11-2014 |
Dengzhu Yan, Northborough, MA US
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20120158007 | INTRAOCULAR LENS TRANSFER CASE - An intraocular lens (IOL) transfer case for transferring an IOL to an injection cartridge includes a lens holder for holding the IOL. The lens holder includes a bore. Folding members within the lens holder are configured to fold the IOL into a partially folded position when the IOL is slid through the bore across the folding members. The IOL transfer case also includes an interface configured to removably connect to an injection cartridge. The interface is positioned to deliver the IOL in the partially folded position within the injection cartridge when the interface is connected to the injection cartridge. The IOL transfer case also includes a plunger connected to the lens holder and configured to push the IOL in the partially folded position through the bore to deliver the IOL into the injection cartridge. | 06-21-2012 |
20140142586 | LENS DELIVERY SYSTEM - An intraocular lens delivery system includes an injector body having a bore surrounded by an inner wall. The system further includes a plunger configured to fit within the bore. The system also includes a plurality of deflectable members connected to the plunger and configured to contact the inner wall and to be deflected when the plunger is inserted within the bore. The deflectable members center the shaft and, when inserted within the injector body, contribute to producing a predetermined force resisting advancement of the plunger when deflected in the bore. | 05-22-2014 |
20150359624 | LENS DELIVERY SYSTEM - An intraocular lens delivery system includes an injector body having a bore surrounded by an inner wall. The system further includes a plunger configured to fit within the bore. The system also includes a plurality of deflectable members connected to the plunger and configured to contact the inner wall and to be deflected when the plunger is inserted within the bore. The deflectable members center the shaft and, when inserted within the injector body, contribute to producing a predetermined force resisting advancement of the plunger when deflected in the bore. | 12-17-2015 |
Dingxue Yan, Grafton, MA US
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20100166819 | Transforming Growth Factor Modulators - The invention is related to compounds of formula (I) that can be used as antagonists of the TGFβ family type I receptors, Alk5 and/or Alk4, compositions and methods of use. The compounds of formula (I) can be employed in the prevention and/or treatment of diseases such as fibrosis (e.g., renal fibrosis, pulmonary fibrosis, and hepatic fibrosis), progressive cancers, or other diseases for which reduction of TGFβ family signaling activity is desirable. | 07-01-2010 |
Dingxue Yan, South Grafton, MA US
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20100159455 | RECEPTOR FAMILY PROFILING - The invention provides compositions and methods, e.g., assay technologies and their use in biodetection and diagnostics. More particularly, the invention provides compositions and methods based on nucleic acid-templated chemistry in biodetection and profiling of receptors (and their families) and proteins (and their families), and the use of same in diagnostics. | 06-24-2010 |
Guang Yan, Worcester, MA US
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20150297718 | IONTOPHORESIS DELIVERY OF CATIONIC PRODRUGS FOR TOPICAL TREATMENT OF MUSCULOSKELETAL OR SKIN DISEASES - The present invention provides a method for topical delivery of pharmacologically active chemicals into local tissues (skin, subcutaneous, muscle and joint tissues) via the administration of their specially designed cationic prodrugs with anode iontophoresis. The pharmacologically active chemicals are either negatively charged or neutral under the physiologic pH, which are not suitable to be delivered with the anode iontophoresis. The cationic prodrugs of such pharmacologically active chemicals are suitable for anode iontophoresis for improving delivery efficiency of these drugs into the local tissues. The cationic prodrugs can also be used in co-delivery with other cationic drugs such as vasoconstrictors or local anesthetic agents by iontophoresis for treatment of disorders in the local tissues. The anode iontophoresis delivery of the specially designed cationic prodrugs can provide higher drug concentrations in the local tissues, which can be used for better topical treatment of musculoskeletal diseases or skin diseases. | 10-22-2015 |
Huang Yan, Billerica, MA US
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20130295077 | TREATMENT OF SANFILIPPO SYNDROME TYPE B - Among other things, the present invention provides methods and compositions of treating Sanfilippo syndrome type B (Sanfilippo B) by, e.g., intrathecal (IT) administration of a Naglu protein. A suitable Naglu protein can be a recombinant, gene-activated or natural protein. In some embodiments, a suitable Naglu protein is a recombinant Naglu protein. In some embodiments, a recombinant Naglu protein is a fusion protein containing a Naglu domain and a lysosomal targeting moiety. In some embodiments, the lysosomal targeting domain is an IGF-II moiety. | 11-07-2013 |
James Zhimin Yan, West Roxbury, MA US
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20130144206 | Medical Device With Contextual Awareness - A medical device, such as an infusion pump, obtains a contextual awareness of its operation by communicating with centralized patient records and or other medical equipment communicating with a common patient, and/or provides real time advisory information, at care point or remotely. A protocol obtained by the medical device from a protocol server provides context-aware protocols and necessary predicate information for those protocols. This predicate information may be discovered by the medical device communicating with electronic medical records and the associated medical equipment. | 06-06-2013 |
Jane W. Yan, Andover, MA US
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20130031281 | USING A DMA ENGINE TO AUTOMATICALLY VALIDATE DMA DATA PATHS - The disclosed embodiments provide a system that uses a DMA engine to automatically validate DMA data paths for a computing device. During operation, the system configures the DMA engine to perform a programmable DMA operation that generates a sequence of memory accesses which validate the memory subsystem and DMA paths of the computing device. For instance, the operation may include a sequence of reads and/or writes that generate sufficient data traffic to exercise the computing device's I/O controller interface and DMA data paths to memory to a specified level. The system initiates this programmable DMA operation, and then checks outputs for the operation to confirm that the operation executed successfully. | 01-31-2013 |
Jun Yan, Franklin, MA US
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20150198593 | METHOD AND SYSTEM OF MICROFLUIDIC IMMUNOASSAY USING MAGNETIC BEADS - A microfluidic Western blot method and system including a microfluidic western blot method for immunoassay of proteins, the method including introducing a sample including the proteins onto a chip; electrophoretically separating the proteins; binding the separated proteins to beads to form protein-attached beads, the beads being magnetic; flowing the protein-attached beads into a magnetic holding region; applying a magnetic field to the magnetic holding region to fix the protein-attached beads in place within the magnetic holding region; binding primary antibodies to target proteins on the protein-attached beads; binding secondary antibodies to the bound primary antibodies; and detecting the bound secondary antibodies. | 07-16-2015 |
Jun Yan, Reading, MA US
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20110217018 | COMPACT THERMAL ACTUATED VARIABLE OPTICAL ATTENUATOR - A MEMS variable optical attenuator (VOA) chip includes a frame having a planar surface, a micro-electric actuator with a movable optical shutter arranged with respect to the planar surface of the frame, where the VOA is actuated by thermal expansion. The micro-electric actuator comprises semiconductor conductors (“wires”) that can be moved, upon applying an electrical current, by thermal expansion. In one embodiment, the MEMS VOA chip is configured in a multiple wire arrangement that restricts the shutter movement in a plane. | 09-08-2011 |
Jun Yan, Westborough, MA US
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20120254827 | VERIFICATION OF COMPUTER-EXECUTABLE CODE GENERATED FROM A MODEL - In an embodiment, a model is sliced into a plurality of slices. A slice in the plurality of slices is selected. A portion of code, that corresponds to the selected slice, is identified from code generated from the model. The identified code is verified to be equivalent to the selected slice. Equivalence may include equivalent functionality, equivalent data types, equivalent performance, and/or other forms of equivalence between the selected slice and the identified generated code. | 10-04-2012 |
20120254830 | VERIFICATION OF COMPUTER-EXECUTABLE CODE GENERATED FROM A MODEL - In an embodiment, a model is sliced into a plurality of slices. A slice in the plurality of slices is selected. A portion of code, that corresponds to the selected slice, is identified from code generated from the model. The identified code is verified to be equivalent to the selected slice. Equivalence may include equivalent functionality, equivalent data types, equivalent performance, and/or other forms of equivalence between the selected slice and the identified generated code. | 10-04-2012 |
20140380269 | VERIFICATION OF COMPUTER-EXECUTABLE CODE GENERATED FROM A MODEL - In an embodiment, a model is sliced into a plurality of slices. A slice in the plurality of slices is selected. A portion of code, that corresponds to the selected slice, is identified from code generated from the model. The identified code is verified to be equivalent to the selected slice. Equivalence may include equivalent functionality, equivalent data types, equivalent performance, and/or other forms of equivalence between the selected slice and the identified generated code. | 12-25-2014 |
Li Yan, Wellesley, MA US
Liying Yan, Ashland, MA US
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20130116143 | DETECTION AND ANALYSIS OF EPIGENETIC AND GENETIC CHANGES IN TUMOR TISSUE - The invention generally relates to a novel method and related compositions for detecting and analyzing cancer. More particularly, the invention relates to unique methods, compositions and assays useful for diagnosing and measuring the presence and/or risk of ovarian cancer involving the utilization of various generic and epigenetic biomarkers. | 05-09-2013 |
Mingdi Yan, Arlington, MA US
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20160045612 | FUNCTIONALIZED NANOPARTICLES FOR MEDICAL TREATMENTS - A class of functionalized nanoparticles useful in medical treatments is described. The nanoparticles have an attached carbohydrate that is selected on the basis that a cell to be treated ingests as a consequence of the presence of the carbohydrate. The nanoparticles have an attached chemical that if inside the cell is capable of treating the cell (e.g., curing a disease condition in the cell, killing the cell if it is pathogenic, or improving the health of the cell). The nanoparticle carries the chemical preferentially into the cell because the cell will ingest the carbohydrate, and thereby allows the nanoparticle and the chemical into itself. | 02-18-2016 |
Mingdi Yan, Tewksbury, MA US
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20130252843 | METHOD OF MAKING AND USING FLUORESCENT-TAGGED NANOPARTICLES AND MICROARRAYS - Disclosed embodiments concern differentiating and classifying one or more targets using a perhalophenylazide-derived nanoparticle probe, or multiple such probes. Particular embodiments concern using statistical analysis to produce score plots illustrating the level of differentiation and/or classification. Also disclosed are methods for making perhalophenylazide-derived nanoparticle probes, individually or by using a microarray technique. Particular embodiments concern methods for using the per halophenylazide-derived nanoparticle probes to diagnose, detect, and/or treat a disease. Kits comprising the perhalophenylazide-derived nanoparticle probes are also disclosed. | 09-26-2013 |
Nan Yan, Boston, MA US
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20110142854 | COMPOSITIONS AND METHODS FOR INHIBITION OF RETROVIRUSES - Described herein are methods and compositions for the inhibition of retroviral integration and replication. The methods and compositions inhibit the activity of one or more components of the SET complex or base excision repair enzymes and induce autointegration of retroviral double-stranded nucleic acid. | 06-16-2011 |
Peter Z. Yan, Allston, MA US
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20110078879 | Device for Organizing and Maintaining the Patency of Lines - One aspect of the invention relates to a device that efficiently folds and organizes tubing and cords while not compromising their function. In certain embodiments, the device provides dynamic length adjustment in the form to reducing line length, and the device organizes the lines in parallel, making it easier to identify their connections. | 04-07-2011 |
Qingsheng Yan, Wayland, MA US
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20150020221 | Compositions and Methods for the Modulation of DNA Damage Responses Using BAL1 and BBAP - The invention provides methods and compositions for enhancing the efficacy of cancer therapies through modulation of BAL1 and/or BBAP. Also provided are methods for predicting the efficacy of cancer therapies or treating cancer in a subject through modulation of BAL1 and/or BBAP. Further provided are methods for identifying compounds that are capable of modulating BAL1-BBAP complexes. | 01-15-2015 |
Ruqiang Yan, Amherst, MA US
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20090222228 | MULTI-SCALE ENVELOPING SPECTROGRAM SIGNAL PROCESSING FOR CONDITION MONITORING AND THE LIKE - A signal processing technique that decomposes complex, dynamically changing non-stationary signals from machine components such as bearings into different scales by means of a continuous wavelet transform. The envelope signal in each scale is then calculated from the modulus of the wavelet coefficients. Subsequently, Fourier transform is performed repetitively on the envelope of the signal at each scale, resulting in an “envelope spectrum” of the original signal at the various scales. The final output is a three-dimensional scale-frequency map that indicates the intensity and location of the defect-related frequency lines. The technique is generic in nature, and applicable not only to machine condition monitoring, but also to the health monitoring of a wide range of dynamic systems, including human beings. | 09-03-2009 |
Tingxin Yan, Amherst, MA US
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20130173513 | CONTEXT-BASED DEVICE ACTION PREDICTION - The described implementations relate to automatically performing device actions. One implementation can obtain a contextual value of a contextor. The implementation can decide, using a decision engine, whether to perform an action on a computing device based on the contextual value. In an instance when the decision engine decides that the action is to be performed, the implementation can perform the action on the computing device. The implementation can also update the decision engine using feedback related to the action. As a specific example, the action can be prelaunching an application before a user has requested to execute the application. Prelaunching the application can reduce application latency relative to waiting for the user to request to execute the application before launching the application. | 07-04-2013 |
Xiao Yan, Chesnut Hill, MA US
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20120326097 | Half-Heusler Alloys with Enhanced Figure of Merit and Methods of Making - Thermoelectric materials and methods of making thermoelectric materials having a nanometer mean grain size less than 1 micron. The method includes combining and arc melting constituent elements of the thermoelectric material to form a liquid alloy of the thermoelectric material and casting the liquid alloy of the thermoelectric material to form a solid casting of the thermoelectric material. The method also includes ball milling the solid casting of the thermoelectric material into nanometer mean size particles and sintering the nanometer size particles to form the thermoelectric material having nanometer scale mean grain size. | 12-27-2012 |
Xiao Yan, Chestnut Hill, MA US
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20130175484 | Half-Heusler Alloys with Enhanced Figure of Merit and Methods of Making - Thermoelectric materials and methods of making thermoelectric materials having a nanometer mean grain size less than 1 micron. The method includes combining and arc melting constituent elements of the thermoelectric material to form a liquid alloy of the thermoelectric material and casting the liquid alloy of the thermoelectric material to form a solid casting of the thermoelectric material. The method also includes ball milling the solid casting of the thermoelectric material into nanometer mean size particles and sintering the nanometer size particles to form the thermoelectric material having nanometer scale mean grain size. | 07-11-2013 |
Xiao Yan, Brighton, MA US
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20080202575 | METHODS FOR HIGH FIGURE-OF-MERIT IN NANOSTRUCTURED THERMOELECTRIC MATERIALS - Thermoelectric materials with high figures of merit, ZT values, are disclosed. In many instances, such materials include nano-sized domains (e.g., nanocrystalline), which are hypothesized to help increase the ZT value of the material (e.g., by increasing phonon scattering due to interfaces at grain boundaries or grain/inclusion boundaries). The ZT value of such materials can be greater than about 1, 1.2, 1.4, 1.5, 1.8, 2 and even higher. Such materials can be manufactured from a thermoelectric starting material by generating nanoparticles therefrom, or mechanically alloyed nanoparticles from elements which can be subsequently consolidated (e.g., via direct current induced hot press) into a new bulk material. Non-limiting examples of starting materials include bismuth, lead, and/or silicon-based materials, which can be alloyed, elemental, and/or doped. Various compositions and methods relating to aspects of nanostructured thermoelectric materials (e.g., modulation doping) are further disclosed. | 08-28-2008 |
20110108778 | THERMOELECTRIC SKUTTERUDITE COMPOSITIONS AND METHODS FOR PRODUCING THE SAME - Compositions related to skutterudite-based thermoelectric materials are disclosed. Such compositions can result in materials that have enhanced ZT values relative to one or more bulk materials from which the compositions are derived. Thermo-electric materials such as n-type and p-type skutterudites with high thermoelectric figures-of-merit can include materials with filler atoms and/or materials formed by compacting particles (e.g., nanoparticles) into a material with a plurality of grains each having a portion having a skutterudite-based structure. Methods of forming thermoelectric skutterudites, which can include the use of hot press processes to consolidate particles, are also disclosed. The particles to be consolidated can be derived from (e.g., grinded from), skutterudite-based bulk materials, elemental materials, other non-Skutterudite-based materials, or combinations of such materials. | 05-12-2011 |
20150068574 | METHODS FOR HIGH FIGURE-OF-MERIT IN NANOSTRUCTURED THERMOELECTRIC MATERIALS - Thermoelectric materials with high figures of merit, ZT values, are disclosed. In many instances, such materials include nano-sized domains (e.g., nanocrystalline), which are hypothesized to help increase the ZT value of the material (e.g., by increasing phonon scattering due to interfaces at grain boundaries or grain/inclusion boundaries). The ZT value of such materials can be greater than about 1, 1.2, 1.4, 1.5, 1.8, 2 and even higher. Such materials can be manufactured from a thermoelectric starting material by generating nanoparticles therefrom, or mechanically alloyed nanoparticles from elements which can be subsequently consolidated (e.g., via direct current induced hot press) into a new bulk material. Non-limiting examples of starting materials include bismuth, lead, and/or silicon-based materials, which can be alloyed, elemental, and/or doped. Various compositions and methods relating to aspects of nanostructured theromoelectric materials (e.g., modulation doping) are further disclosed. | 03-12-2015 |
Xiaomin Yan, Norwood, MA US
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20100156492 | SYSTEM AND METHOD FOR THERMAL LIMIT CONTROL - This disclosure relates to a system and method for pulse generation. A system in accordance with the present disclosure may include a power dissipating element configured to receive power from a power source. At least one of the power source and the power dissipating element may be configured to generate a first signal. The system may further include a measuring instrument in communication with the power source. The measuring instrument may be configured to measure the first signal and to provide an input corresponding to a measured signal to a duty cycle limiter. The system may also include a pulse controller operatively connected to the power source. The pulse controller may be configured to control a duty cycle of the first signal and to receive a second signal from the duty cycle limiter. The pulse controller may be configured to disable at least one of the power source and the power dissipating element if the duty cycle limiter has determined that a maximum condition has been exceeded. Other embodiments are also within the scope of the present disclosure. | 06-24-2010 |
20130030422 | HANDHOLDABLE LASER DEVICE FEATURING SENSOR FOR EYE SAFE ACTIVATION - A laser device for treating skin is provided which includes a handholdable housing; a laser member arranged within the housing emitting an output beam; a capacitance sensor arranged at the first end of the housing which includes a plate surrounding and defining a window through which the output beam exits, the plate having at least three segments with each flexibly movable in and out of a common plane, each of the segments being connected to an electrode, the electrodes operating to determine dielectric constants of a skin surface; a signal and control storage device communicating with the sensor comparing input signals of measured dielectric constant values to a stored standard dielectric constant value, and wherein emission of the output beam is activated to fire only when all of the at least three segments align in a plane and sense the stored standard dielectric constant value. | 01-31-2013 |
Xinhua Yan, Boston, MA US
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20110085976 | METHODS FOR DETECTING CARDIAC DAMAGE - The present invention relates to a method for detecting heart damage in a patient. The invention also relates to methods for treatment of patients identified as having heart damage. The invention further pertains to methods for evaluating the efficacy of an ongoing therapeutic regimen designed to treat a damaged heart in a patient. | 04-14-2011 |
20140057861 | COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING ANTHRACYCLINE INDUCED CARDIOTOXICITY - The invention features methods and compositions feature lapatinib and/or rapamycin for treating or preventing a cardiac condition induced by anthracycline treatment. | 02-27-2014 |
20140378377 | Methods for Detecting Cardiac Damage - The present invention relates to a method for detecting heart damage in a patient. The invention also relates to methods for treatment of patients identified as having heart damage. The invention further pertains to methods for evaluating the efficacy of an ongoing therapeutic regimen designated to treat a damaged heart in a patient. | 12-25-2014 |
Xuri Yan, Boston, MA US
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20120193836 | Electrospinning Process for Manufacture of Multi-Layered Structures - Devices and methods for high-throughput manufacture of concentrically layered nanoscale and microscale fibers by electrospinning are disclosed. The devices include a hollow tube having a lengthwise slit through which a core material can flow, and can be configured to permit introduction of sheath material at multiple sites of Taylor cone formation. | 08-02-2012 |
20150035181 | PATTERNED SLIT FIXTURES AND SURFACES FOR HIGH THROUGHPUT SLIT-SURFACE ELECTROSPlNNING - The present invention relates generally to the field of electrospinning. In particular, the present invention relates to an electrospinning device that includes a slit-fixture defined by an elongate aperture disposed between opposing elements of an electrically conductive material. These elements include a variety of patterns/shapes that affect the flow of fluid through the aperture and the electrical field across the aperture. | 02-05-2015 |
Xuri Yan, Brighton, MA US
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20130241115 | Electrospinning Process for Manufacture of Multi-Layered Structures - Devices and methods for high-throughput manufacture of concentrically layered nanoscale and microscale fibers by electrospinning are disclosed. The devices include a hollow tube having a lengthwise slit through which a core material can flow, and can be configured to permit introduction of sheath material at multiple sites of Taylor cone formation formation. | 09-19-2013 |
20140103583 | SYSTEMS AND METHODS FOR FACILITATING THE GENERATION OF CORE-SHEATH TAYLOR CONES IN ELECTROSPINNING - Systems and methods for electrospinning of core-sheath fibers are provided. The systems and methods achieve optimization of a shear stress that exists at a fluid boundary between core and sheath polymer solutions, by varying certain parameters of an electrospinning apparatus and/or the solutions used therewith. | 04-17-2014 |
20160096304 | SYSTEMS AND METHODS FOR FACILITATING THE GENERATION OF CORE-SHEATH TAYLOR CONES IN ELECTROSPINNING - Systems and methods for electrospinning of core-sheath fibers are provided. The systems and methods achieve optimization of a shear stress that exists at a fluid boundary between core and sheath polymer solutions, by varying certain parameters of an electrospinning apparatus and/or the solutions used therewith. | 04-07-2016 |
Xuri Ray Yan, Brighton, MA US
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20140322512 | CORE-SHEATH FIBERS AND METHODS OF MAKING AND USING SAME - According to one aspect of the invention, multicomponent fiber are provided, which comprise (a) a polymeric core that comprises a core-forming polymer and (b) a polymeric sheath that comprises a sheath-forming polymer that is different than the core-forming polymer. Examples of core-forming polymers include, for instance, crosslinked polysiloxanes and thermoplastic polymers, among others. Examples of sheath-forming polymers include, for instance, solvent-soluble polymers, degradable polymers and hydrogel-forming polymers, among others. Other aspects of the present invention pertain to methods of forming such multicomponent fibers. For example, in certain preferred embodiments, the multicomponent fibers are formed using coaxial electrospinning techniques. Still other aspects of the present invention pertain to meshes and other articles that are formed using the multicomponent fibers. | 10-30-2014 |
Yan Yan, Jamaica Plain, MA US
Patent application number | Description | Published |
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20110071967 | Automatic Labeler Assignment - A method, including receiving multi-labeler data that includes data points labeled by a plurality of labelers; building a model from the multi-labeler data, wherein the model includes an input variable that corresponds to the data points, a label variable that corresponds to true labels for the data points, and variables for the labels given by the labelers; and executing the model, in response to receiving new data points, to determine a level of expertise of the labelers for the new data points. | 03-24-2011 |
Yanhua Yan, Westford, MA US
Patent application number | Description | Published |
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20100239605 | Recombinant Rhinovirus Vectors - The invention provides recombinant rhinovirus vectors including, for example, influenza virus antigens. Also provided by the invention are corresponding pharmaceutical compositions and methods. | 09-23-2010 |
20100297169 | Novel Neutralizing Immunogen (NIMIV) of Rhinovirus and its Use for Vaccine Applications - The invention relates to methods and compositions for preventing or treating human rhinovirus infection. | 11-25-2010 |
20110091501 | Recombinant Rhinovirus Vectors - The invention provides rhinovirus vectors, which can be used in the delivery of immunogens, such as influenza virus immunogens, and corresponding compositions and methods. | 04-21-2011 |
20110110973 | Influenza B Vaccines - This invention relates to immunogenic compositions including influenza B virus sequences, and methods of using such compositions. | 05-12-2011 |
20140161833 | NOVEL NEUTRALIZING IMMUNOGEN (NIMIV) OF RHINOVIRUS AND ITS USES FOR VACCINE APPLICATIONS - The invention relates to methods and compositions for preventing or treating human rhinovirus infection. | 06-12-2014 |