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Xu, PA

Chang Xu, Macungie, PA US

Patent application numberDescriptionPublished
20110126735BLACK PEARLESCENT PIGMENT WITH A METAL LAYER - A pearlescent effect pigment having an opaque, dark or black color is disclosed. The black pearlescent pigment includes a platelet-shaped non-metal substrate, optionally an oxide layer, a template layer, and a metal layer. The pearlescent luster of the disclosed effect pigment is comparable to those of pure pearlescent effects. The disclosed method provides a cost-effective approach for the manufacturing of the disclosed effect pigment.06-02-2011
20110130510POLYMER ENCAPSULATED ALUMINUM PARTICULATES - A coated platelet that includes a robust polymer coating that has substantially uniform structures, a method for producing the coated platelet and a system that includes the coated platelet are described. The disclosed method involves immobilizing initiator molecules onto the surfaces of the platelet by using surface coupling groups and polymerization from initiating sites of the initiator anchored on the surface of the platelet. The disclosed method allows uniform growth of the polymer chains so as to produce robust coated platelets with a smooth coated surface. The disclosed system includes only the disclosed coated platelet and a solvent and eliminates the need to add polymer resins separate from the resins that are covalently attached to the platelet.06-02-2011
20120022181FILM-FORMING PIGMENTS AND COATING SYSTEM INCLUDING THE SAME - A coated pigment that includes polymer encapsulations which act as a pigment dispersant and film forming agent, coating systems that include the coated pigment and methods for producing the coated pigment and the coating system are described. The polymer encapsulations of the coated pigments allow the coated pigments that are included in the coating system to be dispersed without the addition of any other dispersants and/or resins. Thus, the disclosed coated pigments simplify the process of making coating systems. The disclosed coated pigments also extend the shelf-life of the coating systems, and provide a final coating with enhanced pigment orientation and aesthetics.01-26-2012
20120022198COLORED SYSTEM - A colored system including a coated substrate and a color pigment that adheres to the coated substrate, and a method for producing the colored system are described. The disclosed method adheres effectively the color pigments to the coated substrates. The resulting colored system avoids their separation during coating applications. The colored metallic paints/inks can be prepared by mixing a color pigment solution with a coated substrate solution. The resulting colored system displays vivid color and strong metallic luster.01-26-2012
20130040057BLACK PEARLESCENT PIGMENT WITH A METAL LAYER - A pearlescent effect pigment having an opaque, dark or black color is disclosed. The black pearlescent pigment includes a platelet-shaped non-metal substrate, optionally an oxide layer, a template layer, and a metal layer. The pearlescent luster of the disclosed effect pigment is comparable to those of pure pearlescent effects. The disclosed method provides a cost-effective approach for the manufacturing of the disclosed effect pigment.02-14-2013

Patent applications by Chang Xu, Macungie, PA US

Chang Xu, Allentown, PA US

Patent application numberDescriptionPublished
20140076201COATING OF METAL PIGMENTS USING PHOSPHONIC ACID-BASED COMPOUNDS - A coated metal pigment that has excellent passivation, dispersion and adhesion properties, a method for producing the coated metal pigment and a coating composition that includes the coated metal pigment are described. The disclosed method generally involves the use of a compound with the following formula (A)03-20-2014

Changliang Xu, Pittsburgh, PA US

Patent application numberDescriptionPublished
20120175188Multi - Function Ladder Attachment - An multi-function attachment for straight and extension ladder for enabling a ladder to stand upright upon an uneven or inclined surface, boosting ladder's stability on cable and wire rope, keeping ladder away from gutter, keeping ladder at roof peak, and providing a support for a work table or sawhorse. The attachment comprise one special device clamped over one rung and stile of the ladder, an extension with shoe that has slip-resistant rubber pad bottom can be vertically adjustable in the device or can be bolted onto device horizontally.07-12-2012

Chunchun Xu, Pittsburgh, PA US

Patent application numberDescriptionPublished
20140265972Load Commutated Inverter Drive Systems for High Power Drive Applications - A load commutated inverter (LCI) drive system for a synchronous electrical machine is provided. The system may include a first supply bridge and a second supply bridge, each of which may include an alternating current to direct current (AC-to-DC) source side converter, a DC link circuit, and a DC-to-AC load side inverter. The system may include a controller for selectively controlling at least one of the first supply bridge and the second supply bridge by selective firings of SCRs. The electrical power outputted from the first supply bridge and the second supply bridge may be combined by an output delta-wye electric power transformer and supplied to the electrical machine. The LCI drive system may further include one or more input electric power transformers configured to supply an input electric power to the first supply bridge and the second supply bridge.09-18-2014

Gann Xu, Boothwyn, PA US

Patent application numberDescriptionPublished
20080274430UV RADIATION BLOCKING PROTECTIVE LAYERS COMPATIBLE WITH THICK FILM PASTES - This invention relates to novel compositions comprising a protective polymer layer and a UV blocking agent. This is used in the fabrication of electronic devices using thick film pastes. The present invention is also an electronic device fabrication process using the compositions. The protective polymer layer is fabricated from materials, which are insoluble after irradiation in the ester-type solvents contained in the thick film paste. By appropriate selection of protective film polymers, the protective film can be compatible with the thick film paste and can be further used to shield portions of the thick film paste from UV irradiation.11-06-2008
20120109660Integrated process and system for cosmetic vehicle repairs - The present invention is directed to an integrated process and system for cosmetic vehicle repair. The invention provides a process and a system to produce repair formulas, repair estimates, and repair scheduling. The present invention is particularly directed to a process and a system for repairing coating defect of a vehicle.05-03-2012

Patent applications by Gann Xu, Boothwyn, PA US

Guoyang Xu, New Town, PA US

Patent application numberDescriptionPublished
20080212914Transparent conducting components and related electro-optic modulator devices - New electro-optic (EO) phase modulator devices and geometries, as can be constructed using a transparent conductive component.09-04-2008
20110058766Transparent Conducting Components and Related Electro-Optic Modulator Devices - New electro-optic (EO) phase modulator devices and geometries, as can be constructed using a transparent conductive component.03-10-2011

Guozhang Xu, Bensalem, PA US

Patent application numberDescriptionPublished
20090111855SUBSTITUTED PHENOXY THIAZOLIDINEDIONES AS ESTROGEN RELATED RECEPTOR-alpha MODULATORS - The present invention relates to compounds of Formula (I),04-30-2009
20110150864SUBSTITUTED AMINOTHIAZOLONE INDAZOLES AS ESTROGEN RELATED RECEPTOR-ALPHA MODULATORS - The present invention relates to compounds of Formula (I),06-23-2011
20110200586AMINOTHIAZOLONES AS ESTROGEN RELATED RECEPTOR-ALPHA MODULATORS - The present invention relates to compounds of Formula (I),08-18-2011
20110200587AMINOTHIAZOLONES AS ESTROGEN RELATED RECEPTOR-ALPHA MODULATORS - The present invention relates to compounds of Formula (I),08-18-2011
20110237625SUBSTITUTED PHENOXY THIAZOLIDINEDIONES AS ESTROGEN RELATED RECEPTOR-a MODULATORS - The present invention relates to compounds of Formula (I),09-29-2011
20110294780SUBSTITUTED THIAZOLIDINEDIONE INDAZOLES, INDOLES AND BENZOTRIAZOLES AS ESTROGEN-RELATED RECEPTOR-a MODULATORS - The present invention relates to compounds of Formula (I),12-01-2011
20120157412Substituted Pyrimidinyl Oxime Kinase Inhibitors - The present invention is directed to substituted pyrimidine compounds of formula (I):06-21-2012
20120302544SUBSTITUTED AMINOTHIAZOLONE INDAZOLES AS ESTROGEN RELATED RECEPTOR-ALPHA MODULATORS - The present invention relates to compounds of Formula (I),11-29-2012
20120302610PICOLINAMIDO-PROPANOIC ACID DERIVATIVES USEFUL AS GLUCAGON RECEPTOR ANTAGONISTS - The present invention is directed to picolanmido-propanoic acid derivatives, pharmaceutical compositions containing them and their use in the treatment and/or prevention of disorders and conditions ameliorated by antagonizing one or more glucagon receptors, including for example metabolic diseases such as Type II diabetes mellitus and obesity.11-29-2012
20120302641BIPHENYL DERIVATIVES USEFUL AS GLUCAGON RECEPTOR ANTAGONISTS - The present invention is directed to biphenyl derivatives, pharmaceutical compositions containing them and their use in the treatment and/or prevention of disorders and conditions ameliorated by antagonizing one or more glucagon receptors, including for example metabolic diseases such as Type II diabetes mellitus and obesity.11-29-2012
20140256657DUAL SGLT1/SGLT2 INHIBITORS - The present invention relates to compounds of Formula (I),09-11-2014

Patent applications by Guozhang Xu, Bensalem, PA US

He Xu, Lansdowne, PA US

Patent application numberDescriptionPublished
20140312000OXYGEN ABSORBING CAP - An oxygen absorbing cap includes a hollow chamber, a removable top that is adapted to screw into or snap into the cap so as to close the hollow chamber and, when removed, to provide access to the hollow chamber, an oxygen absorber adapted to fit into the hollow chamber, and a waterproof breathable film (e.g., e-PTFE microporous film) located in the hollow chamber between the oxygen absorber and any liquid in the bottle and adapted to prevent the liquid in the bottle from contacting the oxygen absorber but allowing gases in the bottle to contact the oxygen absorber. The cap may also be used with a valve that limits the amount of air that contacts the liquid to the air that replaces the poured liquid or used with a pump that replaces the poured liquid with oxygen-free air so that air never contacts liquid in the bottle.10-23-2014

Hongyu Xu, Phoenixville, PA US

Patent application numberDescriptionPublished
20100120715BETA-LACTAMASE INHIBITORS - Disclosed herein are α-aminoboronic acids and their derivatives which act as inhibitors of beta-lactamases. Also disclosed herein are pharmaceutical compositions comprising α-aminoboronic acids and methods of use thereof.05-13-2010
20100286092BETA-LACTAMASE INHIBITORS - Disclosed herein are α-aminoboronic acids and their derivatives which act as inhibitors of beta-lactamases. Also disclosed herein are pharmaceutical compositions comprising α-aminoboronic acids and methods of use thereof.11-11-2010
20100292185BETA-LACTAMASE INHIBITORS - Disclosed herein are α-aminoboronic acids and their derivatives which act as inhibitors of beta-lactamases. Also disclosed herein are pharmaceutical compositions comprising α-aminoboronic acids and methods of use thereof.11-18-2010

Jiang Xu, Havertown, PA US

Patent application numberDescriptionPublished
20150087610Method of Modifying Fertility - The present invention provides methods and compositions for modifying fertility in a male mammalian subject by contacting the subject's testis cells, germ cells or sperm with a sufficient amount of a composition comprising a ligand that binds, activates, or inhibits activation of, a TAS2R receptor expressed on the cells. Also described are methods for screening a test molecule for its effect on fertility by examining changes in male germ cells, testis cells or sperm resulting from contact with a molecule that binds, activates, or inhibits activation of, a TAS2R receptor expressed on the cells. Compositions for modifying fertility in a mammalian subject, e.g., contraceptive products, include a ligand that binds, inhibits or activates a TAS2R receptor in a pharmaceutically acceptable carrier.03-26-2015

Jianguo Xu, Wrightstown, PA US

Patent application numberDescriptionPublished
20100107634Rankine Cycle For LNG Vaporization/Power Generation Process - A method and system for generating power in a vaporization of liquid natural gas process, the method comprising pressurizing a working fluid; heating and vaporizing the working fluid; expanding the working fluid in one or more expanders for the generation of power, the working fluid comprises: 2-11 mol % nitrogen, methane, a third component whose boiling point is greater than or equal to that of propane, and a fourth component comprising ethane or ethylene; cooling the working fluid such that the working fluid is at least substantially condensed; and recycling the working fluid, wherein the cooling of the working fluid occurs through indirect heat exchange with a pressurized liquefied natural gas stream in a heat exchanger, and wherein the flow rate of the working fluid at an inlet of the heat exchanger is equal to the flow rate of the working fluid at an outlet of the heat exchanger.05-06-2010
20100313933Reflector-solar receiver assembly and solar module - A reflector-solar receiver assembly and methods related to the reflector-solar receiver assembly are described. The reflector-solar receiver assembly contains a reflector and a solar receiver. The reflector has a substantially planar light reflecting face and the solar receiver has a substantially planar light receiving face. The normal direction of the light reflecting face and the normal direction of the light receiving face are at an angle of about 90°. The reflector-solar receiver assembly can be installed at an installation site by placing the substantially planar light reflecting face at an angle of about γ−23.5° or about γ+23.5° from the gravitation line of the installation site, γ is the latitude of the installation site, so that the substantially planar light reflecting face reflects at least a portion of sunlight to the substantially planar light receiving face during a majority of the clear days of a year.12-16-2010
20110308275METHOD AND SYSTEM FOR PERIODIC COOLING, STORING, AND HEATING OF ATMOSPHERIC GAS - Disclosed is a method and a system. The method and system involve compressing an atmospheric gas stream to form a supercritical atmospheric gas stream, forming at least a first stream from the supercritical atmospheric gas stream, directing the first stream to a regenerator for cooling to form a first cooled stream, directing the first cooled stream from the regenerator, expanding the first cooled stream to form a liquefied atmospheric gas stream, storing at least a portion of the liquefied atmospheric gas stream, pressurizing at least a portion of the stored portion of the liquefied atmospheric gas stream, and heating at least a portion of a pressurized liquefied atmospheric gas stream in the regenerator. In the method and system, refrigeration below the critical temperature of the atmospheric gas is directly or indirectly provided to at least one portion of the system from a non-combustible source.12-22-2011
20110308276METHOD AND SYSTEM FOR PERIODIC COOLING, STORING, AND HEATING WITH MULTIPLE REGENERATORS - Disclosed are a method and system involving pressurizing an atmospheric gas stream to form at least a compressed atmospheric gas stream, directing the compressed atmospheric gas stream to a first regenerator for cooling, pressurizing to above a second predetermined pressure to form at least a supercritical atmospheric gas stream, directing the supercritical atmospheric gas stream to a second regenerator for cooling, reducing pressure to form at least a liquefied atmospheric gas stream, selectively storing the liquefied atmospheric gas stream, pressurizing the liquefied atmospheric gas stream to form at least a pressurized liquefied atmospheric gas stream, heating the pressurized liquefied atmospheric gas stream in the second regenerator to form at least a heated stream, expanding the heated stream to form at least a medium pressure atmospheric gas stream, directing the medium pressure atmospheric gas stream to the first regenerator, and heating the medium pressure atmospheric gas stream in the first regenerator.12-22-2011
20110308761REGENERATOR, REGENERATION PROCESS, AND LIQUID POLYMER MIXTURE FOR A REGENERATOR - Disclosed is a regenerator, a regeneration process, and a liquid polymer mixture for periodic cooling, storing, and heating of atmospheric gas. The regenerator, the regeneration process, and the liquid polymer mixture involve a liquid polymer that remains in contact with a thermally conductive solid material during a first operational period and a second operational period of a regeneration process.12-22-2011
20120255312Method and System to Produce Electric Power - An open brayton cycle power generation system is enabled and improved by integration of an energy storage system utilizing cryogenic storage of atmospheric gas. A particular improved system is an open brayton cycle power generation system in which the heating source is Concentrating Solar Power. Multiple embodiments are described which permit various modes of operation and improved overall efficiency.10-11-2012
20130219956He-3 Recovery From Natural Helium By Distillation - A system and method for recovering helium-3 from helium. A distillation column having a top section that is smaller in diameter than a main section is provided. The column also includes an intermediate condenser located in the main section and above a helium feed stream. Reflux to the column can be provided by liquid helium-3 from a conduit or from an overhead condenser. In a preferred cycle, the distillation column is operated at a subatmospheric pressure, and in a temperature range between 2.3 K and 4.3 K.08-29-2013
20130219958HE-3 RECOVERY FROM NATURAL HELIUM BY DISTILLATION - A system and method for recovering helium-3 from helium. A distillation column having a top section that is smaller in diameter than a main section is provided. The column also includes an intermediate condenser that condenses vapor from the main section and above a helium feed stream. Reflux to the column can be provided by liquid helium-3 from a conduit or from an overhead condenser. In a preferred cycle, the distillation column is operated at a subatmospheric pressure, and in a temperature range between 2.3 K and 4.3 K.08-29-2013
20130239807Pressure Swing Adsorption Process - A process for separating a primary gas component from a feed gas mixture comprising the primary gas component and secondary gas components in four or more adsorption beds. The process comprises subjecting each of the four or more adsorption beds to a repetitive cycle. The repetitive cycle comprises, in sequence, a feed step, a pressure decreasing equalization step, a provide purge step, a blowdown step, a purge step, a pressure increasing equalization step, and a repressurization step. During the pressure decreasing equalization step, rinse gas is co-currently introduced simultaneous with the withdrawal of pressure equalization gas. Rinse gas is formed by compressing blowdown gas and/or purge gas effluent from the adsorption bed undergoing the purge step. The process is particularly suited for separating H09-19-2013
20130243686Hydrogen Production Process with Low CO2 Emissions - A hydrogen production process wherein steam and a hydrocarbon feed is reacted in a prereformer, the prereformed intermediate is further reacted in an oxygen-based reformer, the reformate is shifted and then separated by a pressure swing adsorber to form a H09-19-2013
20130255492Adsorption Process - A process for separating a first gas, for example CO10-03-2013
20140053594THERMALLY ACTIVATED PRESSURE BOOSTER FOR HEAT PUMPING AND POWER GENERATION - Thermally activated systems and related processes for raising the pressure of a gaseous working fluid are described. The systems and processes can be used for both winter heating and summer cooling with increased efficiency. They can also be used for other applications in need of an efficient thermally driven compressor, such as a power generation process.02-27-2014
20140353886Purification, Recovery, and Recycle of Vent Gas - An apparatus and/or system and method for recycling vent gas from an autoclave is disclosed including cooling and cleaning a vent gas, introducing the cooled and cleaned resultant stream into a purification unit to remove at least a portion of the carbon dioxide and water vapor contained therein, and recycling the purified stream enriched in oxygen into the autoclave or another process requiring enriched oxygen.12-04-2014
20140373713Pressure Swing Adsorption Process - A pressure swing adsorption process for an adsorption system having 12 adsorption beds, the process having a cycle with 5 pressure equalization steps. Background is provided for the various pressure swing adsorption cycle steps.12-25-2014
20150376527CO2 CAPTURE FROM CO2-RICH NATURAL GAS - It is described a prefractionation-physical absorption hybrid process and system for separation of a CO12-31-2015

Patent applications by Jianguo Xu, Wrightstown, PA US

Jianguo Xu, Wrightsown,, PA US

Patent application numberDescriptionPublished
20150376527CO2 CAPTURE FROM CO2-RICH NATURAL GAS - It is described a prefractionation-physical absorption hybrid process and system for separation of a CO12-31-2015

Jigeng Xu, Boothwyn, PA US

Patent application numberDescriptionPublished
20080286450Method and composition for reducing waste in photo-imaging applications - Waste reduction, including hazardous waste reduction in photoimaging processes can be accomplished by improving diffusional resolution of cationic curable compositions. The addition of fluorinated polymers including fluorinated surfactants provides improved diffusional resolution in cationic and/or radical based photoimaging formulations allowing for image accuracy improvements, and reduced product and process waste quantity and disposal cost. These fluorinated surfactants also allow for increased cure speed, and non-hazardous constituent formulations that result in less wasted material and time.11-20-2008
20100001437METHOD AND COMPOSITION FOR REDUCING WASTE IN PHOTO-IMAGING APPLICATIONS - Waste reduction, including hazardous waste reduction in photoimaging processes can be accomplished by improving diffusional resolution of cationic curable compositions. In preferred embodiments stereolithographic articles are formed with a reduced production of waste by forming an article from a cationic composition; removing excess composition from the formed article using an air knife or liquid C001-07-2010
20100201019Method and composition for reducing waste in photo-imaging applications - Waste reduction, including hazardous waste reduction in photoimaging processes can be accomplished by improving diffusional resolution of cationic curable compositions. The addition of fluorinated polymers including fluorinated surfactants provides improved diffusional resolution in cationic and/or radical based photoimaging formulations allowing for image accuracy improvements, and reduced product and process waste quantity and disposal cost. These fluorinated surfactants also allow for increased cure speed, and non-hazardous constituent formulations that result in less wasted material and time.08-12-2010
20120178020METHOD AND COMPOSITION FOR REDUCING WASTE IN PHOTO-IMAGING APPLICATIONS - Waste reduction, including hazardous waste reduction in photoimaging processes can be accomplished by improving diffusional resolution of cationic curable compositions. The addition of fluorinated polymers including fluorinated surfactants provides improved diffusional resolution in cationic and/or radical based photoimaging formulations allowing for image accuracy improvements, and reduced product and process waste quantity and disposal cost. These fluorinated surfactants also allow for increased cure speed, and non-hazardous constituent formulations that result in less wasted material and time.07-12-2012

Patent applications by Jigeng Xu, Boothwyn, PA US

Jingyi Xu, York, PA US

Patent application numberDescriptionPublished
20080226892FIBER-FILLED MOLDED ARTICLES - Polymer molding processes, such as injection-molding processes, include use of a viscosity-reducing supercritical fluid additive resulting in less breakage of reinforcing fibers upon introduction into the mold.09-18-2008
20100086636POLYMER PROCESSING SYSTEMS INCLUDING SCREWS - Injection molding and blow molding systems that include screws having low L:D ratios are provided. The systems are capable of producing microcellular polymeric materials. In some cases, the systems may be formed by retrofitting conventional polymer processing systems. Retrofitting may involve changing (e.g., machining or replacing) existing components of the conventional system, as well as, adding new components to the system. For example, retrofitting generally involves replacing the conventional polymer processing screw with a new screw designed to satisfy conditions needed for processing microcellular materials. In other cases, the systems may be newly manufactured. The retrofitted or newly manufactured systems of the invention are considerably less expensive than newly manufactured microcellular processing systems having higher L:D ratios.04-08-2010

Patent applications by Jingyi Xu, York, PA US

Jinsuo Xu, Fort Washington, PA US

Patent application numberDescriptionPublished
20090076303Process for selective reduction of propionic acid from (meth)acrylic acid product streams - The present invention relates to an improved process for the selective reduction of propionic acid, hereinafter “PA”, impurity from an acrylic acid, hereinafter “AA” stream.03-19-2009
20110077424Process for recovering valued compounds from a stream derived from purification of methyl methacrylate - The present invention provides a method for extractive recovery and conversion of selected compounds, such as methacrylic acid (MAA) and 2-methacrylamide (MAM), from a stream derived from purification of methyl methacrylate (MMA) or methacrylic acid (MAA) produced via a conventional ACH route process.03-31-2011
20130338396PROCESS FOR PRODUCTION OF METHACRYLIC ACID ESTER HAVING INCREASED YIELD - This invention provides a method for producing α,β-unsaturated carboxylic acid esters in high yield from acetone cyanohydrin and sulfuric acid through the separation and concurrent catalytic conversion of reaction side products to additional α,β-unsaturated carboxylic acid ester product. The catalyst comprises at least one Group IA element and may include a porous support and/or a promoter element selected from at least one of phosphorous, boron, titanium, zinc, zirconium, tin, bismuth, cerium, and alkaline earth metals. The method for producing methacrylic acid esters, such as methylmethacrylate (MMA), comprises the steps of: i) providing an alkyl alcohol and an organic traction comprising an alkyl methacrylate, an alkyl α-hydroxyisobutyrate and an alkoxyisobutyrate; ii) vaporizing at least a portion of the organic fraction and at least a portion of the alkyl alcohol; iii) contacting the vaporized organic fraction and alcohol with a catalyst comprising at least one element selected from the group consisting of lithium, sodium, potassium, rubidium, cesium and francium, to convert the alkyl ahydroxyisobutyrate and alkyl alkoxyisobutyrate to additional alkyl methacrylate and produce a mixture comprising alkyl methacrylate, methacrylic acid, alkyl alcohol, and water.12-19-2013
20140031585STEAM RE-CALCINATION OF MIXED METAL OXIDE CATALYSTS - A process for producing a catalyst for the (amm)oxidation of alkanes comprises calcination of a crystalline mixed metal oxide catalyst partially or wholly in the presence of steam.01-30-2014
20150141694PROCESS FOR PRODUCTION OF METHACRYLIC ACID ESTERS - A method for producing α-, β-unsaturated carboxylic acid esters in high yield from reaction by-product streams via the catalytic conversion of the by-products to additional α-, β-unsaturated carboxylic acid ester product. The catalyst comprises cesium, and phosphorous as a promoter, on a porous support.05-21-2015

Patent applications by Jinsuo Xu, Fort Washington, PA US

Jinsuo Xu, Collegeville, PA US

Patent application numberDescriptionPublished
20160102043PROCESS FOR PRODUCTION OF METHACRYLIC ACID ESTERS - A method for producing α-, β-unsaturated carboxylic acid esters in high yield from acetone cyanohydrin and sulfuric acid through the separation and concurrent catalytic conversion of reaction side products to additional α-, β-unsaturated carboxylic acid ester product. The catalyst comprises at least one Group IA element, and boron as a promoter, on a porous support.04-14-2016

Juan Xu, Monroeville, PA US

Patent application numberDescriptionPublished
20090268159AUTOMATED ASSESSMENT OF OPTIC NERVE HEAD WITH SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY - A fully automated optic nerve head assessment system, based on spectral domain optical coherence tomography, provides essential disc parameters for clinical analysis, early detection, and monitoring of progression.10-29-2009
20120213423BLOOD VESSEL SEGMENTATION WITH THREE DIMENSIONAL SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY - In the context of the early detection and monitoring of eye diseases, such as glaucoma and diabetic retinopathy, the use of optical coherence tomography presents the difficulty, with respect to blood vessel segmentation, of weak visibility of vessel pattern in the OCT fundus image. To address this problem, a boosting learning approach uses three-dimensional (3D) information to effect automated segmentation of retinal blood vessels. The automated blood vessel segmentation technique described herein is based on 3D spectral domain OCT and provides accurate vessel pattern for clinical analysis, for retinal image registration, and for early diagnosis and monitoring of the progression of glaucoma and other retinal diseases. The technique employs a machine learning algorithm to identify blood vessel automatically in 3D OCT image, in a manner that does not rely on retinal layer segmentation.08-23-2012

Qian Xu, State College, PA US

Patent application numberDescriptionPublished
20100309465COHERENT ANTI-STOKES RAMAN HOLOGRAPHY - Apparatus and methods of four wave mixing (FWM) holography are described, including illuminating a sample with a first beam, a second beam, and a third beam, and combining the generated FWM signal with a reference beam at a imaging device to obtain holographic image data. In some examples, the first and second beams may be provided by a single pump-probe beam. The third beam may be a Stokes beam or an anti-Stokes beam. A representative example is coherent anti-Stokes Raman holography (CARS holography), which includes illuminating a sample with a pump/probe beam and a Stokes beam to obtain a CARS signal from the sample; and combining the CARS signal with a reference beam to obtain a CARS hologram.12-09-2010

Ren-Huan Xu, Jenkintown, PA US

Patent application numberDescriptionPublished
20100254981Secreted/Cell Bound Poxvirus Proteins and Methods of Use Thereof as Vaccines and Anti-Viral Agents - Compositions and methods for the treatment and prevention of pox virus infections are disclosed.10-07-2010

Ruisong Xu, Murrysville, PA US

Patent application numberDescriptionPublished
20120156508PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS - Described herein are compounds generally comprising an indeno[2′,3′:3,4]naptho[1,2-b]pyran structure. Such compounds may be useful for their photochromic properties, and be used in certain photochromic compositions. Such compositions may further comprise other photochromic compositions and/or materials. Additionally, such compounds and/or compositions may be suitable for preparing certain photochromic articles.06-21-2012
20120156521PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS - Described herein are compounds generally comprising an indeno[2′,3′:3,4]naptho[1,2-b]pyran structure. Such compounds may be useful for their photochromic properties, and be used in certain photochromic compositions. Such compositions may further comprise other photochromic compositions and/or materials. Additionally, such compounds and/or compositions may be suitable for preparing certain photochromic articles. Also described herein are methods for preparing certain photochromic compounds, compositions, and articles.06-21-2012
20120157677LACTONE COMPOUNDS AND MATERIALS MADE THEREFROM - The present invention relates to lactone compounds represented by the following Formulas I and II, and methods of making such lactone compounds.06-21-2012

Ruisong Xu, Monroeville, PA US

Patent application numberDescriptionPublished
20090146104ALIGNMENT FACILITIES FOR OPTICAL DYES - Various non-limiting embodiments disclosed herein provide phase-separating polymer systems including a cured polymeric liquid crystal matrix phase and a guest phase including at least one photoactive material where the guest phase separates from the matrix phase during the curing process. Optical elements, including ophthalmic elements and other articles of manufacture including the phase-separating polymer systems are also disclosed. Methods of forming a liquid crystal phase-separating photoactive polymer system are also described.06-11-2009
20090323011MESOGEN CONTAINING COMPOUNDS - Compounds including at least one mesogenic substructure and at least one long flexible segment and methods of synthesizing the same are disclosed. Formulations which include various embodiments of the mesogen containing compounds and their use in articles of manufacture and ophthalmic devices are also disclosed.12-31-2009
20090323012LIQUID CRYSTAL COMPOSITIONS COMPRISING MESOGEN CONTAINING COMPOUNDS - Liquid crystal compositions comprising compounds including at least one mesogenic substructure and at least one long flexible segment and a compound selected from a photochromic compound, a dichroic compound and a photochromic-dichroic compound and methods of synthesizing the same and their use in articles of manufacture and ophthalmic devices are disclosed.12-31-2009
20090326186MESOGEN CONTAINING COMPOUNDS - Compounds including at least one mesogenic substructure and at least one long flexible segment and methods of synthesizing the same are disclosed. Formulations which include various embodiments of the mesogen containing compounds and their use in articles of manufacture and ophthalmic devices are also disclosed.12-31-2009
20100014010FORMULATIONS COMPRISING MESOGEN CONTAINING COMPOUNDS - Compounds including at least one mesogenic substructure and at least one long flexible segment and methods of synthesizing the same are disclosed. Formulations which include various embodiments of the mesogen containing compounds and their use in articles of manufacture and ophthalmic devices are also disclosed.01-21-2010
20110128457ALIGNMENT FACILITIES FOR OPTICAL DYES - Provided are phase-separating polymer systems including a cured polymeric liquid crystal matrix phase and a guest phase including at least one photoactive material where the guest phase separates from the matrix phase during the curing process. Optical elements, including ophthalmic elements and other articles of manufacture including the phase-separating polymer systems are also disclosed. Methods of forming a liquid crystal phase-separating photoactive polymer system are also described.06-02-2011
20110129678Photochromic compounds and compositions - Described herein are compounds generally comprising an indeno[2′,3′:3,4]naptho[1,2-b]pyran structure. Such compounds may be useful for their photochromic properties, and be used in certain photochromic compositions. Such compositions may further comprise other photochromic compositions and/or materials. Additionally, such compounds and/or compositions may be suitable for preparing certain photochromic articles. Also described herein are methods for preparing certain photochromic compounds, compositions, and articles.06-02-2011
20120002141MESOGENIC STABILIZERS - The present invention relates to compounds represented by the following Formula Ia,01-05-2012
20120003401MESOGENIC STABILIZERS - The present invention relates to compounds represented by the following Formula I,01-05-2012
20120021144MESOGENIC STABILIZERS - The present invention relates to compounds represented by the following Formula I,01-26-2012
20120027960MESOGENIC STABILIZERS - The present invention relates to compounds represented by the following Formula Ic,02-02-2012

Patent applications by Ruisong Xu, Monroeville, PA US

Sen Xu, Philadelphia, PA US

Patent application numberDescriptionPublished
20090235746Detecting And Measuring Live Pathogens Utilizing A Mass Detection Device - Extremely minute amounts of live pathogens are rapidly detected using a piezoelectric cantilever sensor. A single pathogen is detectable in about 30 minutes. Pathogen-specific antibodies are immobilized on the sensor surface. The sensor is exposed to a medium that potentially contains the target pathogen. When target pathogens are contained in the medium, both dead and live pathogen cells bind to the immobilized antibody on the sensor surface. The attached target pathogen cells are exposed to a pathogen discriminator capable of discriminating between live cells and dead cells by increasing the mass of live cells. Example pathogens include 09-24-2009
20100297687DETECTION AND MEASUREMENT OF MASS CHANGE USING AN ELECTROMECHANICAL RESONATOR - A change in impedance of a electromechanical resonating sensor is utilized to detect and/or measure a change in mass accumulated on the sensor. The impedance is monitored at a fixed frequency. The fixed frequency may be at or near the resonance frequency of the sensor. In various configurations, the sensor comprises a quartz crystal microbalance sensor or a piezoelectric cantilever sensor.11-25-2010

Shuming Xu, Schnecksville, PA US

Patent application numberDescriptionPublished
20080246086SEMICONDUCTOR DEVICES HAVING CHARGE BALANCED STRUCTURE - A laterally diffused metal-oxide-semiconductor transistor device includes a substrate having a first conductivity type with a semiconductor layer formed over the substrate. A source region and a drain extension region of the first conductivity type are formed in the semiconductor layer. A body region of a second conductivity type is formed in the semiconductor layer. A conductive gate is formed over a gate dielectric layer that is formed over a channel region. A drain contact electrically connects the drain extension region to the substrate and is laterally spaced from the channel region. The drain contact includes a highly-doped drain contact region formed between the substrate and the drain extension region in the semiconductor layer, wherein a topmost portion of the highly-doped drain contact region is spaced from the upper surface of the semiconductor layer. A source contact electrically connects the source region to the body region.10-09-2008
20090267145MOSFET DEVICE HAVING DUAL INTERLEVEL DIELECTRIC THICKNESS AND METHOD OF MAKING SAME - A method of forming a metal-oxide-semiconductor (MOS) device includes the following steps: forming a semiconductor layer of a first conductivity type having source and drain regions of a second conductivity type, a channel region and a lightly-doped drain region formed therein; forming a gate over the channel region proximate an upper surface of the semiconductor layer; after the forming steps, depositing a first dielectric layer having a first thickness over an upper surface of the semiconductor layer; etching the first dielectric layer in a region over the lightly-doped drain proximate to the gate to reduce its thickness; conformably depositing a second dielectric layer having a second thickness over the first dielectric layer, including in the etched region, the second thickness being less than the first thickness; and forming a shielding electrode over the second dielectric layer.10-29-2009
20110148376MOSFET WITH GATE PULL-DOWN - A MOSFET main switch transistor has a pull-down FET coupled between a drain thereof and the gate of the main switch transistor. A gate of the pull-down FET is coupled to the drain of the main switch transistor by a capacitor and is connected to a source thereof by a resistor. The pull-down FET is operated by capacitive coupling to the voltage drop across the main switch and can be used to hold the gate of the main switch transistor at or near its source potential to avoid or reduce unintentional turn-on of the main switch transistor by the Miller effect.06-23-2011
20110148506INTEGRATION OF MOSFETS IN A SOURCE-DOWN CONFIGURATION - An output stage for a switched mode power supply has a high-side switch having a first power FET and a first speed-up FET monolithically integrated onto a first die. A low-side switch has a second power FET and a second speed-up FET monolithically integrated onto a second die. A semiconductor device has the power FET and the speed-up FET monolithically integrated in a “source-down” configuration. A method of operating an output stage of a switched mode power supply alternately turns on and off a high-side and a low-side switch and drives at least one of the switches with a speed-up FET monolithically integrated with the switch.06-23-2011
20120012982CAPACITORS AND METHODS OF FORMING - Capacitors and methods of forming semiconductor device capacitors are disclosed. Trenches are formed to define a capacitor bottom plate in a doped upper region of a semiconductor substrate, a dielectric layer is formed conformally over the substrate within the trenches, and a polysilicon layer is formed over the dielectric layer to define a capacitor top plate. A guard ring region of opposite conductivity and peripheral recessed areas may be added to avoid electric field crowding. A central substrate of lower doping concentration may be provided to provide a resistor in series below the capacitor bottom plate. A series resistor may also be provided in a resistivity region of the polysilicon layer laterally extending from the trenched area region. Contact for the capacitor bottom plate may be made through a contact layer formed on a bottom of the substrate. A top contact may be formed laterally spaced from the trenched area by patterning laterally extended portions of one or more of the dielectric, polysilicon and top metal contact layers.01-19-2012
20120175702METAL-OXIDE-SEMICONDUCTOR DEVICE HAVING TRENCHED DIFFUSION REGION AND METHOD OF FORMING SAME - An MOS device includes a semiconductor layer of a first conductivity type and first and second source/drain regions of a second conductivity type formed in the semiconductor layer proximate an upper surface of the semiconductor layer. The first and second source/drain regions are spaced apart relative to one another. A gate is formed above and electrically isolated from the semiconductor layer, at least partially between the first and second source/drain regions. At least a given one of the first and second source/drain regions is configured having an effective width that is substantially greater than a width of a junction between the semiconductor layer and the given source/drain region.07-12-2012
20130009253POWER MOSFET WITH INTEGRATED GATE RESISTOR AND DIODE-CONNECTED MOSFET - A power MOSFET is formed in a semiconductor device with a parallel combination of a shunt resistor and a diode-connected MOSFET between a gate input node of the semiconductor device and a gate of the power MOSFET. A gate of the diode-connected MOSFET is connected to the gate of the power MOSFET. Source and drain nodes of the diode-connected MOSFET are connected to a source node of the power MOSFET through diodes. The drain node of the diode-connected MOSFET is connected to the gate input node of the semiconductor device. The source node of the diode-connected MOSFET is connected to the gate of the power MOSFET. The power MOSFET and the diode-connected MOSFET are integrated into the substrate of the semiconductor device so that the diode-connected MOSFET source and drain nodes are electrically isolated from the power MOSFET source node through a pn junction.01-10-2013
20140183622SCHOTTKY POWER MOSFET - A semiconductor device containing a vertical power MOSFET with a planar gate and an integrated Schottky diode is formed by forming a source electrode on an extended drain of the vertical power MOSFET to form the Schottky diode and forming the source electrode on a source region of the vertical power MOSFET. The Schottky diode is connected through the source electrode to the source region. A drain electrode is formed at a bottom of a substrate of the semiconductor device. The Schottky diode is connected through the extended drain of the vertical power MOSFET to the drain electrode.07-03-2014

Patent applications by Shuming Xu, Schnecksville, PA US

Shuwen Xu, Garnet Valley, PA US

Patent application numberDescriptionPublished
20130183343System and Method of Preparing and Storing Activated Mature Dendritic Cells - The present invention provides compositions and methods for generating and cryopreserving dendritic cells with superior functionality in producing stronger signals to T cells, resulting in a more potent DC-based anti-tumor vaccine. The present invention includes mature, antigen loaded DCs activated by Toll-like receptor agonists that induce clinically effective immune responses, preferably when used earlier in the disease process. The DCs of the present invention produce desirable levels of cytokines and chemokines, and further have the capacity to induce apoptosis of tumor cells. The cells can be cryopreserved and thawed for later use, thereby reducing the need for repeated pheresis and elutriation processes during vaccine production. These methods can also be utilized to directly target molecules involved in carcinogenetic signaling pathways and cancer stem cells.07-18-2013

Tianren Xu, State College, PA US

Patent application numberDescriptionPublished
20120207994CARBON-METAL OXIDE-SULFUR CATHODES FOR HIGH-PERFORMANCE LITHIUM-SULFUR BATTERIES - Embodiments presented herein provide a new approach for high-performance lithium-sulfur battery by using novel carbon-metal oxide-sulfur composites. The composites may be prepared by encapsulating sulfur particles in bifunctional carbon-supported metal oxide or other porous carbon-metal oxide composites. In this way, the porous carbon-metal oxide composite confines sulfur particles within its tunnels and maintain the electrical contact during cycling. Furthermore, the uniformly embedded metal oxides in the structure strongly adsorb polysulfide intermediates, avoid dissolution loss of sulfur, and ensure high coulombic efficiency as well as a long cycle life.08-16-2012
20140017569DOPED CARBON-SULFUR SPECIES NANOCOMPOSITE CATHODE FOR LI-S BATTERIES - We report a heteroatom-doped carbon framework that acts both as conductive network and polysulfide immobilizer for lithium-sulfur cathodes. The doped carbon forms chemical bonding with elemental sulfur and/or sulfur compound. This can significantly inhibit the diffusion of lithium polysulfides in the electrolyte, leading to high capacity retention and high coulombic efficiency.01-16-2014

Ting Xu, Pittsburgh, PA US

Patent application numberDescriptionPublished
20110114184ORGANIC ELECTRONIC DEVICES AND POLYMERS, INCLUDING PHOTOVOLTAIC CELLS AND DIKETONE-BASED AND DIKETOPYRROLOPYRROLE-BASED POLYMERS - Polymers which can be used in p-type materials for organic electronic devices and photovoltaic cells. Compounds, monomers, dimers, trimers, and polymers comprising:05-19-2011
20120152357FLUORO MONOMERS, OLIGOMERS, AND POLYMERS FOR INKS AND ORGANIC ELECTRONIC DEVICES - High performance organic photovoltaic cells based on donor acceptor polymers in the active layer. A composition comprising: at least one copolymer comprising at least one first donor moiety and at least one first acceptor moiety in the copolymer backbone, wherein the first acceptor moiety comprises at least one first ring which is bivalently linked to the copolymer backbone and at least one second ring fused to the first ring and not bivalently linked to the copolymer backbone, wherein the first ring or the second ring comprises two adjacent fluoro ring substituents, and optionally, wherein the donor comprises at least one fused ring system. High efficiency, high Voc, and a combination of both can be achieved.06-21-2012

Weizong Xu, Murrysville, PA US

Patent application numberDescriptionPublished
20090026063SURFACES AND COATINGS FOR THE REMOVAL OF CARBON DIOXIDE - Apparatus suited for removing carbon dioxide from gases are disclosed. The apparatus may employ bodies having a photocatalytic film. Associated methods and compositions are also disclosed.01-29-2009
20110176982SURFACES AND COATINGS FOR THE REMOVAL OF CARBON DIOXIDE - Apparatus suited for removing carbon dioxide from gases are disclosed. The apparatus may employ bodies having a photocatalytic film. Associated methods and compositions are also disclosed.07-21-2011
20130243678SURFACES AND COATINGS FOR THE REMOVAL OF CARBON DIOXIDE - Apparatus suited for removing carbon dioxide from gases are disclosed. The apparatus may employ bodies having a photocatalytic film. Associated methods and compositions are also disclosed.09-19-2013

Patent applications by Weizong Xu, Murrysville, PA US

Xiangling Xu, Pittsburgh, PA US

Patent application numberDescriptionPublished
20090038512CRYSTALLINE COLLOIDAL ARRAYS WITH INORGANIC SOL-GEL MATRIX - A radiation diffractive material that diffracts radiation according to Bragg's law is disclosed. The material includes an ordered periodic array of diffracting regions received within a matrix, the matrix comprising an inorganic sol-gel.02-12-2009
20100315703ANGLE SWITCHABLE CRYSTALLINE COLLOIDAL ARRAY FILMS - A radiation diffractive film is disclosed, which includes a viewing surface, with at least a portion of the viewing surface residing in a viewing plane. The film comprises an ordered periodic array of particles received in a matrix material, the array of particles having a crystalline structure, wherein the crystalline structure defines (i) a plurality of first crystal planes of the particles that diffract infrared radiation and (ii) a plurality of second crystal planes of the particles that diffract visible radiation.12-16-2010
20110135888CRYSTALLINE COLLOIDAL ARRAY OF PARTICLES BEARING REACTIVE SURFACTANT - A crystalline colloidal array of particles is disclosed, which includes reactive surfactant covalently bound to the particle surfaces. During formation of the array, the bound surfactant remains in position on the particles resulting in reduced quantity of defects compared to arrays of particles produced with non-reactive surfactants.06-09-2011
20110267677THERMALLY RESPONSIVE CRYSTALLINE COLLOIDAL ARRAYS - A thermally responsive material comprising an ordered periodic array of particles received in a substantially nonaqueous matrix composition. The material diffracts radiation in a first wavelength band when the material is at a first temperature and the material diffracts radiation in a second wavelength band when the material is at a second temperature.11-03-2011
20120120984TEMPERATURE SENSITIVE COMPOSITE FOR PHOTONIC CRYSTALS - A composite photonic crystal comprising an inverse opal structure defining an ordered array of voids with a filler composition received within the voids. A property of the filler composition changes in response to a stimulus, such as a temperature change, thereby changing the band gap of radiation that is reflected by the composite photonic crystal.05-17-2012
20120148846COLOR PLUS CLEAR COATING SYSTEMS EXHIBITING DESIRABLE APPEARANCE AND FINGERPRINT RESISTANCE PROPERTIES AND RELATED METHODS - Disclosed are methods of forming a multi-component composite coating on a substrate. The methods include applying a transparent radiation curable film-forming composition onto a colored base coat deposited upon a substrate to form a transparent top coat over the basecoat. The colored base coat includes a colorant and a film-forming resin, and the transparent radiation curable film-forming composition includes a fluorine-containing radiation curable compound.06-14-2012
20130075676COMPOSITE CRYSTAL COLLOIDAL ARRAY WITH PHOTOCHROMIC MEMBER - The invention includes a composite material for use in a security device including a radiation diffracting component that exhibits a first optical effect and a photochromic component that exhibits a second optical effect. The composite material is particularly suited for use in authenticating articles, such as currency.03-28-2013
20130077169HOLLOW PARTICLE CRYSTALLINE COLLOIDAL ARRAYS - The invention includes a radiation diffracting member having a crystalline structure comprising an ordered periodic array of hollow particles. The radiation diffracting member also includes a matrix material in which the array of particles is received.03-28-2013
20140242270METHODS FOR REPAIRING DEFECTS IN AUTOMOTIVE COATINGS - A method of repairing defects in automotive coatings is disclosed. More particularly, the invention relates to a method of repairing defects in color-clear composite coatings.08-28-2014
20140242280METHODS AND COMPOSITIONS FOR COATING SUBSTRATES - A method for applying a multilayer coating comprising a basecoat and a clearcoat is disclosed. The basecoat is a curable aqueous composition comprising (1) polymeric particles prepared from ethylenically unsaturated compounds including a multi-ethylenically unsaturated monomer and a keto or aldo-functional monomer, and (2) a polyhydrazide.08-28-2014
20140242281METHODS AND COMPOSITIONS FOR COATING SUBSTRATES - A method for applying a multilayer coating comprising a basecoat and a clearcoat is disclosed. The basecoat is a curable aqueous composition comprising (1) polymeric particles containing carboxylic acid functionality and prepared from ethylenically unsaturated compounds including a multi-ethylenically unsaturated monomer, and (2) a polycarbodiimide.08-28-2014
20140249241OPACIFYING PARTICLES WITH INTERNAL VOID AND METHODS FOR MAKING THE SAME - The invention includes a method of preparing an aqueous dispersion of particles at least partially encapsulated by a polymer, the method comprising dispersing inorganic particles in an aqueous phase; functionalizing at least a portion of the surfaces of the inorganic particles with a coupling agent, the coupling agent having pendent reactive groups; polymerizing the reactive groups on the functionalized particles with a first polymerizable component to produce inner polymer shells surrounding the inorganic particles; polymerizing a second polymerizable component to form outer polymer shells at least partially encapsulating the inner polymer shells; and producing voids within the outer polymer shells, such that the inorganic particles are received within the voids.09-04-2014
20140272419HEAT SENSITIVE SUBSTRATES COATED WITH WATERBORNE COATING COMPOSITIONS - The present invention is directed to a coated substrate comprising: 09-18-2014
20150141588CURABLE COMPOSITIONS THAT INCLUDE HYDRAZIDE FUNCTIONAL MATERIALS - The present invention relates to curable compositions that include a hydrazide functional material (a) represented by the following Formula (I),05-21-2015
20150159030GRAPHENIC CARBON PARTICLE DISPERSIONS AND METHODS OF MAKING SAME - Dispersions of graphenic carbon particles are produced using a polymeric dispersant. The polymeric dispersant includes an anchor block comprising glycidyl (meth)acrylate, 3,4-epoxycyclohexylmethyl(meth)acrylate, 2-(3,4-epoxycyclohexyl)ethyl(meth)acrylate, allyl glycidyl ether and mixtures thereof, reacted with a carboxylic acid comprising 3-hydroxy-2-naphthoic acid, para-nitrobenzoic acid, hexanoic acid, 2-ethyl hexanoic acid, decanoic acid and/or undecanoic acid. The polymeric dispersant also includes at least one tail block comprising at least one (meth)acrylic acid alkyl ester.06-11-2015
20150205010Highly Reflective Crystalline Colloidal Arrays with Radiation Absorbing Particles - A radiation-scattering composition, comprising a plurality of colloidal crystals or aggregates of colloidal crystals, each said crystal comprising radiation reflecting particles in a colloidal array and radiation absorbing particles dispersed in the crystals. The composition scatters radiation in a wavelength band in substantially all directions and absorbs radiation.07-23-2015
20150316686RETROREFLECTIVE COLORANTS - A reflective material comprising a multilayered array of particles encapsulated by a matrix material, the reflective material defining a primary surface, the reflective material exhibiting: (i) visible retroreflection of incident radiation, wherein a wavelength of visible retroreflected radiation decreases from a first visible wavelength at a first angle to the primary surface to a second, shorter wavelength of visible retroreflected radiation as the viewing angle to the primary surface increases; and (ii) Bragg diffraction of the incident radiation, wherein the wavelength of radiation Bragg diffracted normal to the primary surface is longer than the wavelength of visible radiation, such that no visible radiation is retroreflected or Bragg diffracted in a direction normal to the primary surface.11-05-2015
20160075907WATERBORNE COATING COMPOSITIONS AND HEAT SENSITIVE SUBSTRATES COATED THEREWITH - The present invention is directed to a coated substrate comprising: 03-17-2016

Patent applications by Xiangling Xu, Pittsburgh, PA US

Xiaodong Xu, Doylestown, PA US

Patent application numberDescriptionPublished
20090088397INHIBITORS OF SECRETION OF HEPATITIS B VIRUS ANTIGENS FOR TREATMENT OF A CHRONIC HEPATITIS VIRUS - A pharmaceutical composition comprising an effective amount of a compound of formulas (I-III) and a pharmaceutically acceptable carrier. Methods for treating a hepatitis virus in a patient comprising administering an effective amount of the compound of formulas (I-III) are also presented.04-02-2009
200901565777-AMINO ALKYLIDENYL-HETEROCYCLIC QUINOLONES AND NAPHTHYRIDONES - The present invention relates to compounds having a structure according to Formula (I)06-18-2009
20110189771Novel Imino Sugar Derivatives Demonstrate Potent Antiviral Activity and Reducted Toxicity - Imino sugars, such as deoxynojirimycin (DNJ), are glucose analogues that selectively inhibit cellular α-glucosidase I and II (enzymes that process N-linked glycans in glycoprotein) and exhibit broad spectrum antiviral activities against many enveloped viruses. Previously we have reported a novel DNJ derivative, OSL-95II, with antiviral activity and reduced cytotoxicity. In order to develop imino sugars with more potent antiviral activity as well as improved toxicity profile, OSL-95II was modified by diversifying the nitrogen linked alkylated side chain. The antiviral activities were initially tested in bovine viral diarrhea virus (BVDV) infected MDBK cells, yielding several imino sugar derivatives with novel structure and superior antiviral activity and toxicity profile. Furthermore, these new compounds were shown to be active against Dengue virus (DV) and West Nile virus (WNV) infection in BHK cells where potent anti-DV activity having submicromolar EC50 values and SI of greater than 900. These compounds represent a new generation of iminio sugars and their analogues, having application in the clinical treatment of infection of DV and other members of flaviviridae.08-04-2011
20130303552NOVEL INHIBITORS OF SECRETION OF HEPATITIS B VIRUS ANTIGENS - Pharmaceutical compositions of the invention comprise triazolopyrimidines useful for the treatment of hepatitis virus in a patient.11-14-2013
20140206666SULFAMOYLBENZAMIDE DERIVATIVES AS ANTIVIRAL AGENTS AGAINST HBV INFECTION - Pharmaceutical compositions of the invention comprise sulfamoylbenzamide derivative useful as pregenomic RNA encapsidation inhibitors, useful for the treatment of Hepatitis B virus (HBV) infection.07-24-2014
20140249154SUBSTITUTED AMINOTHIAZOLES AS INHIBITORS OF CANCERS, INCLUDING HEPATOCELLULAR CARCINOMA, AND AS INHIBITORS OF HEPATITIS VIRUS REPLICATION - Pharmaceutical compositions of the invention are presented which comprise substituted aminothiazoles derivatives. The substituted aminothiazoles derivatives have a disease-modifying action in the treatment of diseases associated with unregulated cell growth. Such diseases include cancers such as hepatocellular carcinoma, and viral infections from a hepatitis virus.09-04-2014
20150038515INHIBITORS OF HEPATITIS B VIRUS CONVALENTLY CLOSED CIRCULAR DNA FORMATION AND THEIR METHOD OF USE - Pharmaceutical compositions of the invention comprise covalently closed circular DNA formation inhibitors having a disease-modifying action in the treatment of diseases associated with the formation of covalently closed circular DNA that include hepatitis B infection, and any disease involving formation of covalently closed circular DNA.02-05-2015
20150087659NOVEL INHIBITORS OF SECRETION OF HEPATITIS B VIRUS ANTIGENS - Pharmaceutical compositions of the invention comprise triazolopyrimidines useful for the treatment of hepatitis virus in a patient.03-26-2015
20150119366Novel Alkylated Imino Sugars Exhibiting Glucosidase Inhibition and Their Method of Use - Pharmaceutical compositions of the invention comprise alkylated imino sugars derivatives having a disease-modifying action in the treatment of diseases associated with glucosidase activity that include Viral hemorrhagic fevers, and any other diseases involving glucosidase activity.04-30-2015
20150307443FUNCTIONALIZED BENZAMIDE DERIVATIVES AS ANTIVIRAL AGENTS AGAINST HBV INFECTION - Pharmaceutical compositions of the invention comprise functionalized benzamide derivatives useful as pregenomic RNA encapsidation inhibitors, and are useful for the treatment of Hepatitis B virus (HBV) infection.10-29-2015
20150335630Novel Alkylated Imino Sugars Exhibiting Glucosidase Inhibition and Their Method of Use - Pharmaceutical compositions of the invention comprise alkylated imino sugars derivatives having a disease-modifying action in the treatment of diseases associated with glucosidase activity that include Viral hemorrhagic fevers, and any other diseases involving glucosidase activity.11-26-2015
20160024004NOVEL ANTIVIRAL AGENTS AGAINST HBV INFECTION - The present invention provides novel compounds of formula (I) and methods of use thereof. In certain embodiments, the compounds of the invention are useful as nucleocapsid assembly inhibitors. In other embodiments, the compounds of the invention are useful as pregenomic RNA encapsidation inhibitors of Hepatitis B virus (HBV). In yet other embodiments, the compounds of the invention are useful for the treatment of viral infection, including HBV and related viral infections.01-28-2016
20160101074SULFAMOYLBENZAMIDE DERIVATIVES AS ANTIVIRAL AGENTS AGAINST HBV INFECTION - The present invention provides sulfamoylbenzamide derivatives, and pharmaceutical compositions thereof. In certain embodiments, the compounds and pharmaceutical compositions of the invention inhibit pregenomic RNA encapsidation. In other embodiments, the compounds and pharmaceutical compositions of the invention are useful for treating Hepatitis B virus (HBV) infection.04-14-2016

Patent applications by Xiaodong Xu, Doylestown, PA US

Xiaojun Xu, Glenside, PA US

Patent application numberDescriptionPublished
20120228205METHOD AND APPARATUS FOR TREATMENT OF A FLUID - An apparatus for the magnetic treatment of a fluid which produces at least one magnetic field for a period of time, T09-13-2012

Xiaoqing Xu, Spring House, PA US

Patent application numberDescriptionPublished
20100048589Cold Menthol Receptor Antagonists - Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula I as follows:02-25-2010
20100048619Cold Menthol Receptor Antagonists - Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula (I) as follows:02-25-2010
20120136006COLD MENTHOL RECEPTOR ANTAGONISTS - Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula I as follows:05-31-2012

Xlaojun Xu, Glenside, PA US

Patent application numberDescriptionPublished
20080257414Method For Reduction Of Crude Oil Viscosity - The present invention relates to a method for reducing the viscosity and facilitating the flow of petroleum-based fluids. The method includes the step of applying an electric field of sufficient strength and for a sufficient time to the petroleum-based fluid to cause a reduction in viscosity of the fluid.10-23-2008

Yanping Xu, Wynnewood, PA US

Patent application numberDescriptionPublished
20130004477Methods for Treating Inflammation and Oxidative Stress Related Diseases - This invention provides compositions and methods for treating inflammation related diseases. Particularly, the present invention provides methods and compositions of administering thiocyanate to treat inflammation related diseases, such as cystic fibrosis, lung disease, lung cancer, asthma, bronchitis, pancreatic disease, digestive track disease, diabetes, neurological disorder, cardio-vascular disease, atherosclerosis, arthritis, nephritis, or stroke, and neurological disorders such as Alzheimer's disease, Parkinson's disease, multiple sclerosis, or autism. The invention provides the use of thiocyanate to diagnose inflammation related diseases.01-03-2013

Yi Xu, Media, PA US

Patent application numberDescriptionPublished
20110099979Composition and Method for Reducing NOx Emissions From Diesel Engines at Minimum Fuel Consumption - A diesel fuel composition is disclosed, as well as a method for reducing NOx emissions from a diesel engine at minimum fuel consumption wherein the diesel engine operates in a low temperature combustion mode, comprising the step of adding to the diesel engine at least one diesel fuel or blending component for a diesel fuel having a combination of a low T50 in the range of from 190° C. to 280° C., a high cetane number in the range of from 31 to 60, and an effective emissions reducing amount of a nitrogen-free cetane improver.05-05-2011
20110160982ENGINE CONTROL TECHNIQUES TO ACCOUNT FOR FUEL EFFECTS - A technique for engine control to account for fuel effects including providing an internal combustion engine and a controller to regulate operation thereof, the engine being operable to combust a fuel to produce an exhaust gas; establishing a plurality of fuel property inputs; establishing a plurality of engine performance inputs; generating engine control information as a function of the fuel property inputs and the engine performance inputs; and accessing the engine control information with the controller to regulate at least one engine operating parameter.06-30-2011
20110265773Composition and Method for Reducing NOx and Smoke Emissions From Diesel Engines at Minimum Fuel Consumption - A diesel fuel composition is disclosed, as well as a method for reducing NOx and smoke emissions from a diesel engine at minimum fuel consumption which comprises adding to the diesel engine at least one diesel fuel or blending component for a diesel fuel which has a combination of a low T50 in the range of from 190° C. to 280° C., a high cetane number in the range of from 31 to 60, and optionally a high distillation curve slope in the range of from 58° C. to 140° C., which combination is effective to afford a combination of the lowest NO11-03-2011

Yiban Xu, Pittsburgh, PA US

Patent application numberDescriptionPublished
20100322371OPTIMIZED FLOWER TUBES AND OPTIMIZED ADVANCED GRID CONFIGURATIONS - A support grid for a nuclear fuel assembly, the fuel rod assembly having a generally cylindrical fuel rod with a diameter, wherein the support grid includes a frame assembly having a plurality of outer straps and a plurality tubular members and/or helical frame members. The tubular members/helical frame members have a contact portion structured to contact an adjacent helical frame member and at least one helical fuel rod contact portion with a lesser diameter. The lesser diameter is generally equivalent to the fuel rod diameter such that a fuel rod disposed in the helical frame member would engage the inner helical frame member at helical fuel rod contact portion. The helical fuel rod contact portion may have a variable pitch.12-23-2010
20130177127OPTIMIZED FLOWER TUBES AND OPTIMIZED ADVANCED GRID CONFIGURATIONS - A support grid for a nuclear fuel assembly, the nuclear fuel assembly including a generally cylindrical fuel rod with a diameter, wherein the support grid includes a frame assembly having a plurality of generally circular cells and a plurality of helical frame members. The helical frame members are disposed in the cells and are structured to contact the cell as well as a fuel rod. The helical fuel rod contact portion may have a variable pitch.07-11-2013

Yin Xu, Philadelphia, PA US

Patent application numberDescriptionPublished
20130059771Function and Regulation of Angiopoietin-3/Angiopoietin-4 - The present invention relates to Angiopoietin-3 (Ang-3) and Angiopoietin-4 (Ang-4). The present invention also relates to methods of modulating an activity of Ang-3 or Ang-4. The present invention further relates to methods of treating cancer, diabetes, and arthritis.03-07-2013

Yongan Xu, Philadelphia, PA US

Patent application numberDescriptionPublished
20110140305METHOD OF LOW TEMPERATURE IMPRINTING PROCESS WITH HIGH PATTERN TRANSFER YIELD - The present invention is directed to novel methods of imprinting substrate-supported or freestanding structures at low cost, with high pattern transfer yield, and using low processing temperature. Such methods overcome many of the above-described limitations of the prior art. Generally, such methods of the present invention employ a sacrificial layer of film.06-16-2011

Yongjiang Xu, Radnor, PA US

Patent application numberDescriptionPublished
20120115877Facially Amphiphilic Compounds, Compositions, And Uses Thereof In Treating Cancer - The present invention discloses compositions of facially amphiphilic compounds and their use in methods for treating or reducing cancers in animals, such as humans.05-10-2012
20150094294COMPOUNDS AND METHODS FOR TREATING MALARIA - The present disclosure provides compounds, specifically pyrimidin-4,6-dicarboxylic acid amide derivatives, or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing said compounds. Also provided are methods for treating a mammal having malaria, or killing or inhibiting the growth of a 04-02-2015

Yongjiang Xu, Wayne, PA US

Patent application numberDescriptionPublished
20100081665Anti-Malarial Compounds - The present invention provides tricyclic compounds, arylamide compounds, and other compounds, and compositions comprising the same, for treating malaria, and methods of treating malaria comprising administering such compounds to an animal.04-01-2010
20100105703Synthetic Mimetics Of Host Defense And Uses Thereof - The present invention provides arylamide compounds and methods of making and using them as antibiotics.04-29-2010
20130090345Synthetic Mimetics Of Host Defense And Uses Thereof - The present invention provides arylamide compounds and methods of making and using them as antibiotics.04-11-2013
20140308317Polymeric Compounds And Methods Of Making And Using The Same - The present disclosure provides compounds, or pharmaceutically acceptable salts thereof, for inhibiting the growth of a microbe; treating a mammal having a microbial infection, malaria, mucositis, an ophthalmic infection, an otic infection, a cancer, or a 10-16-2014
20150072997ANTI-MALARIAL COMPOUNDS - The present invention provides tricyclic compounds, arylamide compounds, and other compounds, and compositions comprising the same, for treating malaria, and methods of treating malaria comprising administering such compounds to an animal.03-12-2015

Patent applications by Yongjiang Xu, Wayne, PA US

Yun Xu, Langhorne, PA US

Patent application numberDescriptionPublished
20120004303METHOD OF DISPENSING A TEETHING GEL WITH A METERED DOSE APPLICATOR - A method of treating periodontal pain from teething that uses an applicator to dispense a medicament composition, wherein said applicator dispenses a metered dose of a therapeutic amount of said medicament composition.01-05-2012
20130039950NETI-POT PACKET MIXTURE - A nasal rinse composition comprising about 54 to 90 wt. % of sodium chloride and about 10 to 46 wt. % of sodium bicarbonate, and a kit comprising a packet that contains the rinse composition and a nasal rinse dispenser.02-14-2013
20130189201MULTI-PURPOSED DENTIFRICE - The present invention is directed towards anhydrous, single-part multi-purposed dentifrice and methods for removing plague, whitening and remineralizing teeth.07-25-2013

Zhengtian Xu, Glenn Mills, PA US

Patent application numberDescriptionPublished
20100095843Air Pollution Control Filter Elements for Filtration Systems - An improved filtration apparatus, filtering method and filtering material for capturing mercury and other pollutants in pollutant-laden fluid streams such as flue gases generated by process gas streams are disclosed. The improved filtration system may include two pollutant remediation layers, an upstream layer capable of filtering particulates and a downstream layer capable of adsorbing and/or catalyzing pollutants such as mercury, dioxin, furans, and NO04-22-2010

Zhengtian Xu, West Chester, PA US

Patent application numberDescriptionPublished
20120006196Capture of mercury from a gaseous mixture containing mercury - Compositions are provided, derived from chemical treatment of carbonaceous fiber felt forms or other carbonaceous substrates, that exhibit both high efficiency and capacity for mercury capture from flue gases and the like. These compositions are superior to known compositions, particularly with regard to their performance under severely deactivating conditions. The compositions result from the pyrolysis of certain specific sulfur bearing compounds while in contact with activated carbon powders, activated carbon fibers, or with other carbonized forms. Precursor compounds to these novel mercury-binding compositions contain structural moieties that may be represented as:01-12-2012

Zhenrong Xu, Chalfont, PA US

Patent application numberDescriptionPublished
20110021512Cyclic Inhibitors Of 11Beta-Hydroxysteroid Dehydrogenase 1 - This invention relates to novel compounds of the Formula Ik, Im01-27-2011
20120178746CYCLIC INHIBITORS OF 11BETA-HYDROXYSTEROID DEHYDROGENASE 1 - This invention relates to novel compounds of the Formula Ik, Im07-12-2012
20130096108Cyclic Inhibitors of 11Beta-Hydroxysteroid Dehydrogenase 1 - Disclosed is a compound represented by Formula (Im04-18-2013
20130244993SUBSTITUTED 5-,6- AND 7-MEMBERED HETEROCYCLES, MEDICAMENTS CONTAINING SUCH COMPOUNDS, AND THEIR USE - The present invention relates to compounds defined by formula I: wherein the variables A09-19-2013
20130245051CYCLIC UREA INHIBITORS OF 11BETA-HYDROXYSTEROID DEHYDROGENASE 1 - This invention relates to novel compounds of the Formula (I), (Ia) and (Ib), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, j which are useful for the therapeutic treatment of diseases associated with the modulation or inhibition of 11 β-HSD1 in mammals. The invention further relates to pharmaceutical compositions of the novel compounds and methods for their use in the reduction or control of the production of Cortisol in a cell Or the inhibition of the conversion of cortisone to Cortisol in a cell.09-19-2013
20130289050INHIBITORS OF BETA-SECRETASE - The present invention relates to spirocyclic acylguanidines and their use as inhibitors of the β-secretase enzyme (BACE1) activity, pharmaceutical compositions containing the same, and methods of using the same as therapeutic agents in the treatment of neurodegenerative disorders, disorders characterized by cognitive decline, cognitive impairment, dementia and diseases characterized by production of β-amyloid aggregates.10-31-2013
20140057927INHIBITORS OF BETA-SECRETASE - The present invention relates to spirocyclic acylguanidines and their use as inhibitors of the β-secretase enzyme (BACE1) activity, pharmaceutical compositions containing the same, and methods of using the same as therapeutic agents in the treatment of neurodegenerative disorders, disorders characterized by cognitive decline, cognitive impairment, dementia and diseases characterized by production of β-amyloid aggregates.02-27-2014
20140200223INHIBITORS OF BETA-SECRETASE - The present invention is directed to a compound represented by the following structural formula07-17-2014
20150031691INHIBITORS OF BETA-SECRETASE - The present invention relates to compounds represented by Structural Formula (I):01-29-2015
20150080363SUBSTITUTED 5-,6- AND 7-MEMBERED HETEROCYCLES, MEDICAMENTS CONTAINING SUCH COMPOUNDS, AND THEIR USE - The present invention relates to compounds defined by formula I: wherein the variables A03-19-2015
20150150872INHIBITORS OF BETA-SECRETASE - The present invention relates to spirocyclic acylguanidines and their use as inhibitors of the β-secretase enzyme (BACE1) activity, pharmaceutical compositions containing the same, and methods of using the same as therapeutic agents in the treatment of neurodegenerative disorders, disorders characterized by cognitive decline, cognitive impairment, dementia and diseases characterized by production of β-amyloid aggregates.06-04-2015
20150239849INHIBITORS OF BETA-SECRETASE - The present invention relates to spirocyclic acylguanidines and their use as inhibitors of the β-secretase enzyme (BACE1) activity, pharmaceutical compositions containing the same, and methods of using the same as therapeutic agents in the treatment of neurodegenerative disorders, disorders characterized by cognitive decline, cognitive impairment, dementia and diseases characterized by production of β-amyloid aggregates.08-27-2015

Patent applications by Zhenrong Xu, Chalfont, PA US

Zherong Xu, Horsham, PA US

Patent application numberDescriptionPublished
20100317697Renin Inhibitors - Disclosed are compounds having the formula (I): wherein the R12-16-2010
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