Xiaodong Wu
Xiaodong Wu, Beijing CN
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20110055211 | SYSTEM FOR SORTING AND CLASSIFYING USERS OF AN IMAGE INFORMATION MANAGEMENT SYSTEM - A system for sorting and classifying users of an image information management system is disclosed. The system for sorting and classifying users of an image information management system according to the present invention comprises some identical sub-systems, and every two sub-systems are interconnected. The sub-system comprises a user information encoding module, a user information decoding and authority identifying module, a user sorting module, a user classifying module, a command performing module, an authorized user collection database and a resource information database. The resource information database comprises real-time images, history images and control right commands of cradle heads and lens of cameras. The present invention resolves the problem of ordered accessing and utilizing of image information in a super-large-scale advanced real-time monitoring information management system, and realizes the object that local failures do not affect the normal work of the other parts by connecting every two sub-systems to each other and arranging the user identification entrance in each one of sub-systems. | 03-03-2011 |
Xiaodong Wu, Miami, FL US
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20080219402 | Repositionable Gynecological Applicator for Image-guided Radiosurgery (IGRS) and Image-guided Radiation Therapy (IGRT) for Localized Treatment of Gynecological Tumors - A method and apparatus for precisely reproducing the position of a vaginal cylinder in relation to a patient to ensure that a planned radiation dose can be delivered with high precision to the intended treatment target volumes. In order to properly define the treatment volume, a vaginal cylinder with proper diameter is inserted into the patient's vagina. This invention addresses two potential errors: one, the incorrect vaginal cylinder position in relation to the radiation beams, and second, the inconsistent positional correlation between the vaginal cylinder and the patient's body. These two geometric errors will cause dosimetric errors. The present invention provides a method and apparatus for minimizing the geometric error and dosimetric error associated with conventional external beam radiation therapy or radiosurgery used in treating gynecological tumors. First a treatment plan is carried out to determine the treatment target volume. Second, treatment delivery is carried out by using an image-guided system to locate the position of the vaginal cylinder and comparing it relative to the treatment delivery system coordinate system and the patient's coordinate system. The displacement in the position of the vaginal cylinder from the treatment plan is corrected by calculating the transformation matrix and entering the resulting value into a position adjusting assembly. The position adjusting assembly adjusts the vaginal cylinder to exactly reproduce its location relative to the patient's coordinate system. This ensures that the image-guided system locates the precise radiation delivery position and that the radiation dose is delivered precisely to the treatment target volume. | 09-11-2008 |
20090207977 | Laser Aligned Image Guided Radiation Beam Verification Apparatus - A method and apparatus for verifying radiation beam alignment in an image guided stereotactic radiosurgery (SRS) delivery system such as the Cyberknife™. SRS systems such as the Cyberknife™ use a high-precision robotic manipulator with an image-guided system to deliver beams of radiation to a target for optimal clinical results. This radiation delivery system does not usually rotate around a fixed center of axis, therefore a set of pre-programmed positions (nodes) defined as a path is often configured into the system's software to allow proper radiation treatment. In order to achieve the accuracy of the image-guided SRS radiation delivery, these nodes must be calibrated regularly to verify that the radiation beam axis precisely passes through a certain reference point or alignment center with predefined angles. This invention achieves precise verification of radiation beam alignment with a radiation beam detection apparatus mounted on a gimbal assembly. The radiation beam detection apparatus houses an alignment fixture of varying geometric shape, such as a metallic ball or can be an array of radio-opaque markers positioned symmetrically at the gimbal assembly's common rotation center. The radiation detection apparatus comprises a radiation detector such as film and an alignment mirror, which are parallel to each other on opposite sides of the alignment fixture. The radiation detector is used to capture a radiographic image of the alignment fixture and the circular radiation field. The resulting image is analyzed to determine the eccentricity of the radiation field. If the radiation beam is perfectly aligned, the resulting exposure on the film will show a perfectly symmetrically superimposed circular radiation field and the image of the alignment fixture. This method is used to verify beam alignment for each pre-calibrated node and determine whether adjustment to node positions is required. | 08-20-2009 |
20100320402 | Method for Three Dimensional (3D) Lattice Radiotherapy - A method for high-dose Grid radiotherapy utilizing a three-dimensional (3D) dose lattice formation is described herein. The 3D dose lattice can be achieved by, but not limited to, three technical approaches: 1) non-coplanar focused beams; 2) multileaf collimator (MLC)-based intensity modulated radiation therapy (IMRT) or aperture-modulated arc; and 3) heavy charged particle beam. The configuration of a 3D dose lattice is comprised of the number, location, and dose of dose vertices. The optimal configuration of a 3D dose lattice can be achieved by manual calculations or by automating the calculations for a generic algorithm. The objective of the optimization algorithm is to satisfy three conditions via iteration until they reach their global minimum. With 3D dose lattice, high doses of radiation are concentrated at each lattice vertex within a tumor with drastically lower doses between vertices (peak-to-valley effect), leaving tissue outside of the tumor volume minimally exposed. | 12-23-2010 |
20130144212 | DEVICE FOR RADIATION-ACTIVATED LOCALIZED DELIVERY OF TREATMENT AGENTS - The present invention provides for a biocompatible drug delivery device for the targeted treatment of cancer that is implantable within the tumorous mass of a patient. In one embodiment, the device comprises two polarizable elements mechanically coupled by a connecting element. The device also comprises one or more cancer treatment agents. When the polarizable elements are depolarized, such as by the application of ionizing radiation, the two polarizable elements are repelled from each other and release the cancer treatment agent. In another embodiment, one or more treatment agents are expelled from a miniaturized syringe when internal pressure of the device is increased by the production of gas bubbles in response to the application of ionizing radiation. | 06-06-2013 |
20140194667 | Method for Three Dimensional (3D) Lattice Radiotherapy - A method for high-dose Grid radiotherapy utilizing a three-dimensional (3D) dose lattice formation is described herein. The 3D dose lattice can be achieved by, but not limited to, three technical approaches: 1) non-coplanar focused beams; 2) multileaf collimator (MLC)-based intensity modulated radiation therapy (IMRT) or aperture-modulated arc; and 3) heavy charged particle beam. The configuration of a 3D dose lattice is comprised of the number, location, and dose of dose vertices. The optimal configuration of a 3D dose lattice can be achieved by manual calculations or by automating the calculations for a generic algorithm. The objective of the optimization algorithm is to satisfy three conditions via iteration until they reach their global minimum. With 3D dose lattice, high doses of radiation are concentrated at each lattice vertex within a tumor with drastically lower doses between vertices (peak-to-valley effect), leaving tissue outside of the tumor volume minimally exposed. | 07-10-2014 |
Xiaodong Wu US
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20100255475 | DIAGNOSTICS AND THERAPEUTICS FOR OSTEOPOROSIS - Diagnostics and therapeutics for osteoporosis, which are bases upon the identification of a subjects IL-1 haplotype and genotype pattern are described. | 10-07-2010 |
20120115137 | Methods of Predicting Osteoarthritis - The present invention relates generally to methods for predicting progression, initiation and susceptibility of osteoarthritis in human subjects using their genotype test results. | 05-10-2012 |
20120208187 | Method and Kit for Determining Severity and Progression of Periodontal Disease - An improved method and kit of determining whether a patient is predisposed to having severe periodontal disease and/or having high risk of progression of periodontal disease, comprising the steps of (i) taking a biological sample from said patient; (ii) genotyping said biological sample for genetic polymorphism pattern comprising IL 1B (rs16944), IL 1B (rs1143623) and IL 1B (rs4848306); and (iii) comparing said genetic polymorphism patterns to a reference composite genotype pattern; wherein the similarity of said genetic polymorphism patterns to said reference pattern indicate said patient's predisposition to having severe periodontal disease and/or having high risk of progression of periodontal disease. | 08-16-2012 |
Xiaodong Wu, Frisco, TX US
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20100188569 | Multichannel Video Port Interface Using No External Memory - This invention is a video line encapsulation protocol which allows multiple low definition video streams to be combined into a single super frame of high definition video data. Each super frame is formed of individual lines from plural lower definition video input signals. The high definition video frames include meta data in each line identifying the video input source, line and frame. This meta data enables the super frames to be separated into their component input signals within a video processing digital signal processor. | 07-29-2010 |
Xiaodong Wu, Needham, MA US
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20100028893 | METHODS AND COMPOSITIONS FOR PHARMACOGENETIC ANALYSIS OF ANTI-INFLAMMATORY DRUGS IN THE TREATMENT OF RHEUMATOID ARTHRITIS AND OTHER INFLAMMATORY DISEASES - The invention provides methods and compositions for the pharmacogenetic analysis of anti-inflammatory compounds, especially for the pharmacogenetic association of responsiveness to rheumatoid arthritis medications that target TNFα. | 02-04-2010 |
20130337448 | Method and Kit for Determining Severity and Progression of Periodontal Disease - An improved method and kit of determining whether a patient is predisposed to having severe periodontal disease and/or having high risk of progression of periodontal disease, comprising the steps of (i) taking a biological sample from said patient; (ii) genotyping said biological sample for genetic polymorphism pattern comprising IL 1B (rs16944), IL 1B (rs1143623) and IL 1B (rs4848306); and (iii) comparing said genetic polymorphism patterns to a reference composite genotype pattern; wherein the similarity of said genetic polymorphism patterns to said reference pattern indicate said patient's predisposition to having severe periodontal disease and/or having high risk of progression of periodontal disease. | 12-19-2013 |
Xiaodong Wu, Iowa City, IA US
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20090136103 | System and methods for image segmentation in N-dimensional space - A system and methods for the efficient segmentation of globally optimal surfaces representing object boundaries in volumetric datasets is provided. An optical surface detection system and methods are provided that are capable of simultaneously detecting multiple interacting surfaces in which the optimality is controlled by the cost functions designed for individual surfaces and by several geometric constraints defining the surface smoothness and interrelations. The present invention includes surface segmentation using a layered graph-theoretic approach that optimally segments multiple interacting surfaces of a single object using a pre-segmentation step, after which the segmentation of all desired surfaces of the object are performed simultaneously in a single optimization process. | 05-28-2009 |
Xiaodong Wu, Shanghai CN
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20090054570 | TWO COMPONENT WATERBORNE POLYURETHANE COATINGS FOR ANTI-GRAFFITI APPLICATION - Two component (2K) waterborne polyurethane coating compositions which when cured achieve excellent anti-graffiti properties at low VOC level (below 100 g/L) are disclosed. The composition comprises (A) a fluorinated polyol and optionally a non-fluorinated polyol; and (B), a blend of polyisocyanates comprising a hydrophilically modified trimer of hexamethylene diisocyanate (HDT) and a hydrophilic ally modified trimer of isophorone diisocyanate (IPDT). The glass transition temperature of the ambient cured coatings, crosslinked network structure, and fluorine content at the surface enable excellent anti-graffiti properties. The waterborn coatings of the invention have excellent recoatability and exceptional chemical resistance. | 02-26-2009 |
20150087738 | Polyurethane Grout Compositions - The present invention typically provides one-component polyurethane grout compositions and more specially to grout composition useful for seepage control and quick stoppage of water leakage under high water pressure environment, wherein the composition comprises a isocyanate prepolymer and auxiliary components selected from a plasticizer, a silane coupling agent, a catalyst, a cell stabilizer, an anionic surfactant, a filler, a blowing agent or a mixture thereof. The invention also provides the isocyanate prepolymer composition, obtained by reacting a polyfunctional isocyanate, with a polyfunctional polyol comprising at least one polyether polyol containing relatively low amount of ethylene oxide units, and optionally other polyfunctional polyols such as polyester polyols, biorenewable polyols or a mixture thereof, and at least a monofunctional hydroxyl containing compound, wherein the NCO content of said prepolymer is 3%˜18%. The resulting grout composition can cure into a solid under water pressure from 1 MPa to 20 MPa. | 03-26-2015 |
Xiaodong Wu, Lancaster, PA US
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20090004462 | Inorganic-Organic Hybrid Nanocomposite Antiglare and Antireflection Coatings - Embodiments of this disclosure relate to compositions, and a method of making UV or heat curable anti-reflection and anti-glare hard coatings. Such coatings may be useful, for example, for simultaneously improving transmission and preventing undesired visible reflection on various monitor or display panels and optical lenses. For the panels with plastic covers, the coating will also improve the surface mechanical properties such as abrasion and scratch resistance. | 01-01-2009 |
Xiaodong Wu, Coralville, IA US
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20080317308 | System and methods for image segmentation in N-dimensional space - A system and methods for the efficient segmentation of globally optimal surfaces representing object boundaries in volumetric datasets is provided. An optical surface detection system and methods are provided that are capable of simultaneously detecting multiple interacting surfaces in which the optimality is controlled by the cost functions designed for individual surfaces and by several geometric constraints defining the surface smoothness and interrelations. The graph search applications use objective functions that incorporate non-uniform cost terms such as “on-surface” costs as well as “in-region” costs. | 12-25-2008 |
Xiaodong Wu, Jiangsu Providence CN
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20140050990 | Gel Electrolyte, Preparing Method Thereof, Gel Electrolyte Battery, and Preparing Method Thereof - A gel electrolyte, a preparing method thereof, a gel electrolyte battery and a preparing method thereof are provided. The gel electrolyte comprises a non-aqueous solvent and a gel constituent, wherein the non-aqueous solvent comprises lithium salt, and the gel constituent comprises polyethylene glycol compounds with unsaturated double bonds, ester monomers with unsaturated double bonds, silane coupling agents and thermal initiators. The preparing method of the gel electrolyte battery includes preparing non-aqueous solvent containing lithium salts; dividing the prepared non-aqueous solvent containing lithium salts into two parts; adding initiators to one part to obtain a gel electrolyte part A; adding monomers and coupling agents to the other part to obtain a gel electrolyte part B; mixing the gel electrolyte part A and the gel electrolyte part B to obtain a gel electrolyte; injecting the obtained gel electrolyte into a dried battery and allowing the battery standing for 16 to 24 hours so as to sufficiently distribute the gel electrolyte inside the battery, and finally in-situ thermally polymerizing the gel electrolyte. | 02-20-2014 |
Xiaodong Wu, North Miami Beach, FL US
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20140343345 | Method for Fiducial-less Real-time Tracking in Radiation Treatment of Abdominal Tumors - A method for fiducial-less real-time motion tracking of abdominal tumors based on the correlation between the patient's breathing pattern and the diaphragm/lung border during treatment delivery. This invention utilizes an edge detection technique to delineate the diaphragm/lung border on radiographic images in order to calculate or determine tumor locations in the abdomen. The position of the diaphragm/lung border is synchronized with the breathing pattern obtained from continuous optical monitoring of a patient's respiratory cycle. The real-time optical breathing pattern obtained from monitoring is used to determine or calculate the position of the diaphragm/lung border during treatment delivery. The position of the diaphragm/lung border is then used to determine the tumor location in real-time. The target tumor coordinates generated through this process are used by the treatment delivery system to adjust the radiation beam geometry of the treatment delivery system to follow the tumor in real-time and accurately deliver radiation dose. | 11-20-2014 |