Wolter
Wolter Benning, Eindhoven NL
Patent application number | Description | Published |
---|---|---|
20100186179 | RECIPROCATING WORKPIECE DEVICE WITH A DRIVE SYSTEM SEEKING THE RESONANCE OF THE DRIVEN SYSTEM PORTION THEREOF - A workpiece system with a reciprocating motion which includes a motor assembly for producing an output drive signal with a periodic force pulse. The drive signal is coupled to a driven member assembly through a magnetic arrangement, wherein the driven member assembly has a workpiece mounted thereon with a return spring assembly. The driven member assembly has a resonant mechanical frequency. As the RPM of the motor increases from zero following startup, the drive signal frequency increases to the point very near resonance, where the energy from the drive signal is transferred into the reciprocating motion of the driven assembly, producing an effective amplitude of workpiece motion. | 07-29-2010 |
Wolter Marelike, Dresden DE
Patent application number | Description | Published |
---|---|---|
20130236755 | ELECTROCHEMICAL CELL OF AN ACCUMULATOR - The invention relates to electrochemical cells of a rechargeable battery. It is the object of the invention to provide possibilities with which parameters can be determined simply, reliably and with sufficient spatial resolution within the cells of a rechargeable battery in real time and with small additional technical effort. In an electrochemical cell in accordance with the invention, at least one sensor element is arranged within the cell, integrated therein. In this respect, a sensor element is configured as an electrically conductive layer-wise conductor track structure on a surface of a dielectric laminate configured in the form of a thin film. Except for regions arranged at the outer margin provided for an electrical contacting, the conductor track structure is sealed in a fluid-tight manner by a further dielectric laminate which is configured in the form of a film and which is arranged on the conductor track structure. | 09-12-2013 |
Wolter Ten Hoeve, Assen NL
Patent application number | Description | Published |
---|---|---|
20130189184 | PRETARGETING KIT, METHOD AND AGENTS USED THEREIN - Described is a pretargeting method, and related kits, for targeted medical imaging and/or therapeutics, wherein use is made of abiotic reactive chemical groups that exhibit bio-orthogonal reactivity towards each other. The invention involves the use of [4+2] inverse electron demand (retro) Diels-Alder chemistry in providing the coupling between a Pre-targeting Probe and an Effector Probe. To this end one of these probes comprises an electron-deficient tetrazine or other suitable diene, and the other an E-cyclooctene which has one or more axial substituents. | 07-25-2013 |
20140093522 | BIO-ORTHOGONAL DRUG ACTIVATION - The invention relates to a Prodrug activation method, for therapeutics, wherein use is made of abiotic reactive chemical groups that exhibit bio-orthogonal reactivity towards each other. The invention also relates to a Prodrug kit comprising at least one Prodrug and at least one Activator, wherein the Prodrug comprises a Drug and a first Bio-orthogonal Reactive Group (the Trigger), and wherein the Activator comprises a second Bio-orthogonal Reactive Group. The invention also relates to targeted therapeutics used in the above-mentioned method and kit. The invention particularly pertains to antibody-drug conjugates and to bi- and trispecific antibody derivatives. | 04-03-2014 |
20140199331 | BIO-ORTHOGONAL DRUG ACTIVATION - The invention relates to a Prodrug activation method, for therapeutics, wherein use is made of abiotic reactive chemical groups that exhibit bio-orthogonal reactivity towards each other. The invention also relates to a Prodrug kit comprising at least one Prodrug and at least one Activator, wherein the Prodrug comprises a Drug and a first Bio-orthogonal Reactive Group (the Trigger), and wherein the Activator comprises a second Bio-orthogonal Reactive Group. The invention also relates to targeted therapeutics used in the above-mentioned method and kit. The invention particularly pertains to antibody-drug conjugates and to bi- and trispecific antibody derivatives. | 07-17-2014 |
Wolter Ten Hoeve, Eindhoven NL
Patent application number | Description | Published |
---|---|---|
20150344514 | CHEMICALLY CLEAVABLE GROUP - Disclosed is the use of the reactive components of the inverse electron-demand Diels Alder reaction for chemical masking and unmasking in vitro. This can be applied in complex chemical reactions and, particularly in the synthesis of biomolecules, e.g. on solid supports. The reactive components are a dienophile, particularly a trans-cyclooctene, and a diene, particularly a tetrazine. | 12-03-2015 |
Wolter Wolthers, Leiden NL
Patent application number | Description | Published |
---|---|---|
20090127292 | PRESSURE CONTROL DEVICE FOR A CONTAINER - A pressure control device ( | 05-21-2009 |
20110163130 | PRESSURE CONTROL DEVICE FOR A CONTAINER - A pressure control device ( | 07-07-2011 |
Wolter Wolthers, Alphen A/d Rijn NL
Patent application number | Description | Published |
---|---|---|
20120138161 | TAPPING APPARATUS AND COMPRESSIBLE BOTTLE THEREFORE, AND A PREFORM FOR FORMING SUCH CONTAINER - Tapping assembly for beverages, comprising a pressure chamber and a pressurising device, wherein the pressure chamber comprises a lid closing off the pressure chamber at least partly, with an opening in said lid, and a container extending with a neck through said opening and a body extending inside said pressure chamber, wherein a first flange extending around the neck lies at a side of the lid facing the pressure chamber and at least one element extending from said neck lies at the opposite side of the lid, the device being provided with at least one closure element engaging said at least one element, forcing said element away from the lid and thereby pulling the first flange towards the lid for sealing the opening by at least the first flange. | 06-07-2012 |