Patent application number | Description | Published |
20080207682 | Phenylurea Derivatives As Inhibitors Of Tyrosine Kinases For The Treatment Of Tumour Diseases - Compounds of the formula (I), in which R | 08-28-2008 |
20080221118 | Tetrahydroquinoline Derivatives - Compounds of the formula I, in which s, k, I, W, R | 09-11-2008 |
20090030028 | Tetrahydroquinolines - Disclosed are compounds of formula (I), wherein W, R, R | 01-29-2009 |
20090082404 | BENZIMIDAZOLES - Novel compounds of the formula I in which R | 03-26-2009 |
20090118267 | INDANES - Compounds of the formula (I), in which R | 05-07-2009 |
20090286863 | SULFAMATOBENZOTHIOPHENE DERIVATIVES - The invention relates to novel compound of the general formula (I), in which R has the meanings indicated in Claim | 11-19-2009 |
20090306122 | SUBSTITUTED TETRAHYDROPYRROLOQUINOLINE DERIVATIVES AS KINASE MODULATORS, ESPECIALLY OF TYROSINE AND RAF KINASES - Compound of the formula (I), in which X, R | 12-10-2009 |
20100160356 | NOVEL CYCLOBUTYL COMPOUNDS AS KINASE INHIBITORS - The invention relates to compounds of the formula I, to the preparation and use thereof for the preparation of a medicament for the treatment of diseases, in particular tumours and/or diseases in the formation or course of which protein kinases are involved. | 06-24-2010 |
20100168217 | SULFAMATOBENZOTHIOPHENE DERIVATIVES - The invention relates to novel compound of the general formula (I), in which R has the meanings indicated in claim | 07-01-2010 |
20100240676 | THIAZOLE DERIVATIVES - Compounds of the formula (I), in which R | 09-23-2010 |
20110230471 | BENZONAPHTYRIDINE COMPOUNDS AS INHIBITORS OF AUTOTAXIN - Compounds of the formula (I), in which R | 09-22-2011 |
20110237583 | 2, 5-DIAMINO-SUBSTITUTED PYRIDO [4, 3-D] PYRIMIDINES AS AUTOTAXIN INHIBITORS AGAINST CANCER - The present invention relates to pyridopyrimidine derivatives according to formula (I) as autotaxin inhibitors and the use of such compounds for the treatment and/or prophylaxis of physiological and/or pathophysiological conditions, which are caused, mediated and/or propagated by increased lysophosphatic acid levels and/or the activation of autotaxin, in particular of different cancers. | 09-29-2011 |
20120015959 | HETEROCYCLIC COMPOUNDS AS AUTOTAXIN INHIBITORS - Compounds of the formula (I), in which Het, R, X, Y, R | 01-19-2012 |
20120015976 | AUTOTAXIN INHIBITORS - The present invention relates to compounds according to formula (I) as autotaxin inhibitors and the use of such compounds for the treatment and/or prophylaxis of physiological and/or pathophysiological conditions, which are caused, mediated and/or propagated by increased lysophosphatic acid levels and/or the activation of autotaxin, in particular of different cancers. | 01-19-2012 |
20120059016 | PIPERIDINE AND PIPERAZINE DERIVATIVES AS AUTOTAXIN INHIBITORS - The present invention relates to piperidine and pyrazine derivatives according to formulae (Ia), (Ib) and (II) as autotaxin inhibitors and the use of such compounds for the treatment and/or prophylaxis of physiological and/or pathophysiological conditions, which are caused, mediated and/or propagated by increased lysophosphatic acid levels and/or the activation of autotaxin, in particular of different cancers. | 03-08-2012 |
20120115852 | HETEROCYCLIC COMPOUNDS AS AUTOTAXIN INHIBITORS - Compounds of the formula (I), in which R, R | 05-10-2012 |
20120130147 | METHODS FOR THE TREATMENT OF TUMORS WITH INDANE COMPOUNDS - Compounds of the formula (I), in which R | 05-24-2012 |
20120202827 | SULFOXIDE DERIVATIVES FOR THE TREATMENT OF TUMORS - Sulfoxide derivatives of the formula Ia to Im as described, and pharmaceutically usable salts, solvates, enantiomers, tautomers and stereoisomers thereof, including mixtures thereof in all ratios, for the treatment of tumours. | 08-09-2012 |
20130012505 | BENZONAPHTHYRIDINAMINES AS AUTOTAXIN INHIBITORS - The present invention relates to benzonaphthyridinamines of the formula (I) as autotaxin inhibitors and to the use thereof in the treatment and/or prophylaxis of physiological and/or pathophysiological conditions in which the inhibition, regulation and/or modulation of phosphodiesterase or lysophospholipase autotaxin plays a role, in particular of various types of cancer and autoimmune and inflammatory diseases. | 01-10-2013 |
20130023556 | AUTOTAXIN INHIBITORS - The present invention relates to compounds according to formula (I) as autotaxin inhibitors and the use of such compounds for the treatment and/or prophylaxis of physiological and/or pathophysiological conditions, which are caused, mediated and/or propagated by increased lysophosphatic acid levels and/or the activation of autotaxin, in particular of different cancers. | 01-24-2013 |
20130165478 | PYRAZOLOPYRIDINONE DERIVATIVES AS LPA RECEPTOR ANTAGONISTS - The present invention relates to novel pyrazolopyridinone derivatives according to formula (I) and a process of manufacturing thereof. These pyrazolopyridinone derivatives can be used as LPA receptor antagonists for the treatment of various herein disclosed diseases. | 06-27-2013 |
20140148457 | Thiazole derivatives - Compounds of the formula I | 05-29-2014 |
20140343075 | PIPERIDINE AND PIPERAZINE DERIVATIVES AS AUTOTAXIN INHIBITORS - The present invention relates to piperidine and pyrazine derivatives according to formulae (Ia), (Ib) and (II) as autotaxin inhibitors and the use of such compounds for the treatment and/or prophylaxis of physiological and/or pathophysiological conditions, which are caused, mediated and/or propagated by increased lysophosphatic acid levels and/or the activation of autotaxin, in particular of different cancers. | 11-20-2014 |
20150011557 | Benzyl Piperidine Compounds as Lysophosphatidic Acid (LPA) Receptor Antagonist - The invention provides novel substituted benzyl piperidine compounds according to Formula (I) as lysophosphatidic acid (LPA) receptor antagonists, their manufacture and use for the treatment of proliferative or inflammatory diseases, such as cancer, fibrosis or arthritis. | 01-08-2015 |