Patent application number | Description | Published |
20090076631 | CONFIGURING A PHYSICAL CONDITION AT A SOURCE TO OBTAIN A DESIRED PHYSICAL CONDITION AT DESTINATION - An apparatus for determining an operation mode of a device, wherein the device is capable of adjusting a physical condition at a source position to correspondingly influence a physical condition at a destination position, the apparatus comprising a determining unit adapted for determining the operation mode by defining a time dependency of the physical condition at the source position so that a target time-dependency of the physical condition is obtained for the destination position, the target time-dependency representing a resultant variation of the physical condition over time. | 03-19-2009 |
20090145851 | Fluidic system with multiple flow channels - A fluidic system has a flow source adapted for delivering a fluid, a plurality of flow channels, each being adapted for providing a fluid separation and being arranged downstream of the flow source, a flow meter adapted for determining a fluid flow in at least one of the flow channels and being arranged downstream of the at least one of the flow channels, and a control unit adapted for controlling the fluid flow in the at least one of the flow channels in response to the determined fluid flow. | 06-11-2009 |
20090211341 | Leakage Detection Based on Fluid Property Changes - A leakage detection system is described, with the leakage detection system comprising a fluid chamber ( | 08-27-2009 |
20100252502 | HPLC-SYSTEM WITH VARIABLE FLOW RATE - In a high performance liquid chromatography system, wherein a mobile phase is driven through a stationary phase for separating compounds of a sample fluid comprised in the mobile phase, a flow rate of the mobile phase is controlled in dependence on a variation in a control value in the system. | 10-07-2010 |
20110023976 | FLUIDIC DEVICE WITH PLANAR COUPLING MEMBER - A fluidic device for providing fluidic connections is described. The fluidic device comprises a fluid conduit and a planar coupling member with a fluid port, the fluid port being fluidically connected with the fluid conduit. A contour of the planar coupling member is in a predefined relationship with the fluid port's position. | 02-03-2011 |
20120096919 | LIQUID CHROMATOGRAPHY ADJUSTMENT FOR METHOD-CONFORMALLY COMPENSATING DEVIATIONS FROM IDEAL BEHAVIOR - A liquid chromatography device ( | 04-26-2012 |
20120198919 | LIQUID SUPPLY WITH OPTIMIZED SWITCHING BETWEEN DIFFERENT SOLVENTS - A method for metering two or more liquids in controlled proportions in a liquid supply system and for supplying a resultant mixture, in which the liquid supply system includes a plurality of solvent supply lines, a proportioning valve interposed between the solvent supply lines and an inlet of a pumping unit, the method includes drawing in a first liquid into the pumping unit via a first solvent supply line; determining one or more switching points of time for switching between different solvent supply lines, the switching points of time being determined in a way that at said switching points of time, the liquid supplied to the pumping unit is in a predefined pressure range; switching from the first solvent supply line to a second solvent supply line at one of said switching points of time; drawing in a second liquid into the pumping unit via the second solvent supply line. | 08-09-2012 |
20120285558 | PUMP REDUCING A FLUID FLOW BY A DETERMINED AMOUNT - A fluid pump for a fluid separation device for separating a fluid includes a fluid inlet being supplyable with fluid at an inlet pressure (pI), and a fluid conducting mechanism configured for conducting the fluid supplied to the fluid inlet towards a connected fluidic path, in which the fluid conducting mechanism is controllable so that, regardless of a value of the inlet pressure (pI), the fluid is continuously conducted away from the fluid inlet with a definable flow rate (FT). | 11-15-2012 |
20130008523 | INTAKE MONITORING FOR ACCURATE PROPORTIONING - A fluid supply system configured for metering two or more fluids in controlled proportions, including a plurality of solvent supply lines, a pumping unit configured for taking in fluids from selected solvent supply lines and for supplying a pressurized mixture, a proportioning valve configured for modulating solvent composition by sequentially coupling selected ones of the solvent supply lines with the inlet of the pumping unit, a sensor configured for sensing process information in the fluid supply system, an analysis entity configured for analyzing the process information for determining reciprocating element related information at a beginning of fluid intake, and a control unit configured for switching the proportioning valve to sequentially couple selected ones of the solvent supply lines to the inlet of the pumping unit at one or more switching points based on the given metering scheme and based on the reciprocating element related information. | 01-10-2013 |
20130008859 | DRIFTING TWO-DIMENSIONAL SEPARATION WITH ADAPTION OF SECOND DIMENSION GRADIENT TO ACTUAL FIRST DIMENSION CONDITION - A control device for a sample separation apparatus, the sample separation apparatus including a first separation unit and a second separation unit downstream of the first separation unit and supplied with the fluidic sample after treatment by the first separation unit. A control device is configured for controlling the first separation unit to execute a primary separation sequence within a time interval for separating the fluidic sample into fractions, and for controlling the second separation unit to execute secondary separation sequences within the time interval for further separating the separated fractions into sub-fractions, wherein the secondary separation sequences form part of a common sample separation method defined by a common specification of the sample separation involving a set of parameters, and adjusting, over a progress of the primary separation sequence, at least one parameter according to which at least one of the plurality of secondary separation sequences is executed. | 01-10-2013 |
20130267033 | Detection cell with controlled power dissipation - A voltage control circuitry for a detection cell ( | 10-10-2013 |
20140183137 | DRIFTING TWO-DIMENSIONAL SEPARATION WITH ADAPTION OF SECOND DIMENSION GRADIENT TO ACTUAL FIRST DIMENSION CONDITION - A control device for a sample separation apparatus, the sample separation apparatus including a first separation unit and a second separation unit downstream of the first separation unit and supplied with the fluidic sample after treatment by the first separation unit. A control device is configured for controlling the first separation unit to execute a primary separation sequence within a time interval for separating the fluidic sample into fractions, and for controlling the second separation unit to execute secondary separation sequences within the time interval for further separating the separated fractions into sub-fractions, wherein the secondary separation sequences form part of a common sample separation method defined by a common specification of the sample separation involving a set of parameters, and adjusting, over a progress of the primary separation sequence, at least one parameter according to which at least one of the plurality of secondary separation sequences is executed. | 07-03-2014 |
20140251448 | PACKET-WISE PROPORTIONING FOLLOWED BY IMMEDIATE LONGITUDINAL MIXING - A fluid supply system ( | 09-11-2014 |
20140366739 | HPLC SAMPLE INTRODUCTION WITH BYPASS CHANNEL - A sample dispatcher is disclosed and is configured for individually introducing a plurality of portions of one or more sample fluids into a flow of a mobile phase of a liquid separation system. The liquid separation system is configured for separating compounds of the sample fluids and comprises a mobile phase drive configured for driving the mobile phase through a separation unit configured for separating compounds of the sample fluids in the mobile phase. The sample dispatcher comprises one or more sample reservoirs, each configured for receiving and temporarily storing a respective sample fluid portion or at least a part thereof, and a bypass channel. | 12-18-2014 |
20150059451 | PREVENTION OF PHASE SEPARATION UPON PROPORTIONING AND MIXING FLUIDS - A fluid supply system ( | 03-05-2015 |
20150122655 | TWO-DIMENSIONAL FLUID SEPARATION WITH CONTROLLED PRESSURE - A sample separation apparatus ( | 05-07-2015 |
Patent application number | Description | Published |
20090201035 | Contactless detection cell with reduced detection channel cross-section - A contactless detection cell ( | 08-13-2009 |
20100275678 | PRIMARY PISTON CORRECTION DURING TRANSFER - A method for controlling operation of a pump unit, where the pump unit includes a primary piston pump having a primary piston and a secondary piston pump having a secondary piston. The primary piston pump is fluidically connected with the secondary piston pump. The primary piston pump includes an inlet valve and an outlet valve, and the pump unit operates periodically according to a pump cycle. The method includes determining a fluid pressure of fluid dispensed by the pump unit, and performing a closed loop control of a position of the primary piston in dependence on the fluid pressure of the fluid dispensed by the pump unit during a first time interval of the pump cycle. | 11-04-2010 |
20110209766 | Method Transfer Between Fluidic Devices Considering Deviations from Ideal Behavior - An apparatus ( | 09-01-2011 |
20120216886 | PRIMARY PISTON CORRECTION DURING TRANSFER - A method for controlling operation of a pump unit, where the pump unit includes a primary piston pump having a primary piston and a secondary piston pump having a secondary piston. The primary piston pump is fluidically connected with the secondary piston pump. The primary piston pump includes an inlet valve and an outlet valve, and the pump unit operates periodically according to a pump cycle. The method includes determining a fluid pressure of fluid dispensed by the pump unit, and performing a closed loop control of a position of the primary piston in dependence on the fluid pressure of the fluid dispensed by the pump unit during a first time interval of the pump cycle. | 08-30-2012 |
20140305228 | Debris Filter for Fluidic Measurement with Recess Size Decreasing in Fluid Flow Direction - A filter for filtering debris out of a fluid flowing along a fluid flow direction in a fluidic member of a sample separation device, the filter comprising a plurality of filter structures stacked along the fluid flow direction and each having pores with defined pore size, wherein the defined pore size of the stacked filter structures decreases along the fluid flow direction. | 10-16-2014 |
20150204828 | FLUIDIC VALVE WITH SELECTIVLY SWITCHABLE STORAGE PATHS - A sample separation apparatus ( | 07-23-2015 |
Patent application number | Description | Published |
20090082258 | Means and Methods for Treating Advanced Stage Neuroblastoma - The present invention relates to uses of compounds having a structure as shown by formula (I) for the manufacture of a pharmaceutical composition for the treatment of neuroblastoma. Moreover, the present invention encompasses methods of treatment for said diseases. | 03-26-2009 |
20110020334 | METHODS FOR TREATING AND PREVENTING BRAIN TUMORS BASED ON BONE MORPHOGENETIC PROTEINS - The present invention is concerned with the therapy of neuroblastoma and related diseases. Specifically, the present invention relates to a method for treating or preventing neuroblastoma comprising administering to a subject a therapeutically effective amount of bone morphogenetic protein 4 (BMP4). Preferably, said BMP4 is applied together with chemotherapy and/or radiation therapy. | 01-27-2011 |
20130209413 | USE OF PARVOVIRUS FOR ELIMINATING CANCER STEM CELLS (CSCs) - Described is the use of a parvovirus, preferably H-1PV, for the therapeutical elimination of cancer stem cells (CSCs), preferably neuroblastoma stem cells and glioblastoma stem cells. | 08-15-2013 |
20140329905 | HISTONE DEACETYLASE 10-INHIBITOR CO-TREATMENT IN CANCER - The present invention relates to a method of identifying a subject being susceptible to a co-treatment with an histone deacetylase 10 (HDAC10)-inhibitor, said subject being in need of and/or being treated with cancer therapy against a cancer, comprising the steps of a) determining the amount of an HDAC10 gene product and/or an autophagy-related gene 4D (ATG4D) product in a cancer sample from said subject, b) comparing the amount of said HDAC10 gene product as determined in step a) with a reference amount for said HDAC10 gene product and/or the amount of ATG4D product as determined in step a) with a reference amount for said ATG4D product, and c) identifying a subject being susceptible to co-treatment with an HDAC10-inhibitor. Moreover, The present invention relates to a method of predicting the risk of recurrence and/or progression of a cancer in an subject treated by cancer therapy, comprising the steps of a) determining the amount of an HDAC10 gene product and/or an ATG4D product in a cancer sample from said subject, b) comparing the amount of said HDAC10 gene product as determined in step a) with a reference amount for said HDAC10 gene product and/or the amount of ATG4D product as determined in step a) with a reference amount for said ATG4D product, and c) predicting the risk of recurrence and/or progression of a cancer treated by cancer therapy. The present invention also relates to a device for identifying a subject being susceptible to co-treatment with an HDAC10-inhibitor, a kit adapted to carry out the method of the present invention. Finally, the invention relates to 2-(4-butoxyphenyl)-N-hydroxyacetamide (bufexamac) for use in treating cancer in a subject, wherein said bufexamac is to be applied in a co-treatment with cancer therapy. | 11-06-2014 |
Patent application number | Description | Published |
20100047445 | Method for Coating Water-Absorbing Polymer Particles - A process for preparing water-absorbing polymer particles by spraying a liquid onto water-absorbing polymer particles by means of at least one thermally insulated and/or trace-heated spray nozzle in a mixer. | 02-25-2010 |
20100104761 | Method for Coating Water-Absorbing Polymer Particles - A process for preparing water-absorbing polymer particles by spraying a liquid below the product bed surface by means of at least one spray nozzle in a mixer with moving mixing tools. | 04-29-2010 |
20100112200 | Method for Coating Water-Absorbing Polymer Particles - A process for preparing water-absorbing polymer particles by coating water-absorbing polymer particles with a particulate solid in a mixer, wherein the particulate solid is dispersed by means of a gas stream and the supply of the dispersed particulate solid in the mixer ends below the product bed surface. | 05-06-2010 |
20100263420 | PROCESS FOR THE CONTINUOUS GRANULATION OF FERTILIZERS - The present invention relates to a process for the preparation of fertilizer granules. The process is particularly suitable for the preparation of finely divided fertilizer granules. Furthermore, the invention relates to the granulated fertilizers obtainable by this process, and to their use for fertilizing agricultural and/or horticultural crops. | 10-21-2010 |
20110166541 | ADJUSTABLE SOLID PARTICLE APPLICATION SYSTEM - An application system for applying a solid particle includes an injector housing having a material inlet, a gas inlet, and a material outlet, and an occluder moveably disposed within the injector housing between the gas inlet and the material outlet. The injector housing and the occluder define there between at least one adjustable aperture downstream of the material inlet and in fluid communication with the gas inlet and the material outlet. The aperture has a first open area with the occluder in a first position and a second open area with the occluder in a second position, the second open area being different than the first open area. The system also includes a nozzle having a nozzle inlet coupled to the material outlet and a nozzle outlet, the inlet having a circular cross-section and the outlet having a rectangular cross-section. | 07-07-2011 |
20130142007 | Injector for a Granular Solid - The invention relates to an injector ( | 06-06-2013 |
Patent application number | Description | Published |
20120179094 | MEDICAMENT CONTAINER - The invention relates to a medicament container, comprising a cavity at least partially defined by a container wall comprising a soft, flexible inner layer consisting of a soft material and a rigid outer layer consisting of a rigid material, wherein the layers are arranged as a one-piece part by two component injection moulding. | 07-12-2012 |
20120186584 | MEDICAMENT CONTAINER - The invention relates to a medicament container, comprising a bag with an outlet, the bag compressible by a compression means, the bag arranged to be essentially inflexible and arranged for turning flexible in an area subjected to a compression means. The invention further relates to an injection arrangement for delivering a liquid medicament comprising the medicament container. | 07-26-2012 |
20120189476 | Pump Chamber for a Peristaltic Pump - The invention relates to a pump chamber ( | 07-26-2012 |
20120197195 | Drug Delivery Device - A drug delivery device ( | 08-02-2012 |
20120197212 | DRUG DELIVERY DEVICE AND USE OF A ROTATABLE ROLL IN A DRUG DELIVERY DEVICE - A drug delivery device is provided which comprises a housing, a dispensing end for dispensing a drug from the drug delivery device, a flexible container for holding the drug, the flexible container comprising an outlet, the outlet being connected to the dispensing end, and a squeezing member for squeezing the flexible container, wherein, for dispensing a dose of the drug from the drug delivery device, the squeezing member and the flexible container are axially displaceable relative to one another, the squeezing member rotating with respect to the housing during the relative axial displacement and squeezing the flexible container, thereby urging the dose of the drug from the container through the outlet. Furthermore, using a rotatable roll in a drug delivery device is described. | 08-02-2012 |
20120197233 | Injection Arrangement - The invention relates to a pump unit ( | 08-02-2012 |
20120209249 | Injection Arrangement for a Flowable Drug - The invention refers to an injection arrangement ( | 08-16-2012 |
20120220929 | Injection Arrangement - The invention relates to a pump unit ( | 08-30-2012 |
20120253282 | MEDICAMENT CONTAINER - The invention relates to a medicament container for a liquid medicament, the medicament container comprising a bag with an outlet, the bag being compressible or shrinkable by subjection of at least a part of the medicament container to an energy source. | 10-04-2012 |
20120253286 | ARRANGEMENT FOR DELIVERING A FLUID MEDICAMENT - The invention relates to an arrangement for delivering a fluid medicament, the arrangement comprising a medicament container that comprises an array of separated reservoirs. Each reservoir comprises a defined charge of a fluid medicament and is separately dischargeable. The reservoirs are flexible and connected by a connecting element. The arrangement further comprises a dosage apparatus comprising a releasing actor designed to activate the release of the charge of fluid medicament from a reservoir to a needle. The dosage apparatus comprises a transportation arrangement designed to provide the releasing actor with reservoirs to be released, or designed to move the releasing actor to a reservoir to be released next. | 10-04-2012 |
20120266875 | Medicament Container - The invention relates to a medicament container ( | 10-25-2012 |
20120266876 | Medicament Container - The invention relates to a medicament container ( | 10-25-2012 |
20120266877 | Medicament Administration Device - The invention relates to a medicament administration device ( | 10-25-2012 |
20120268741 | ARRANGEMENT FOR DETERMINING A LONGITUDINAL POSITION OF A STOPPER - The invention refers to an arrangement and a method for determining a longitudinal position of a stopper for sealing a compartment of a translucent medicament container for a liquid medicament (M). The arrangement comprises a circular light source and a photo sensitive sensor, wherein either the light source or the sensor is laterally arrangeable next to the medicament container extending over at least part of the length of the medicament container, and wherein the respective other of the light source and the sensor is arrangeable in a circular manner around a head of the medicament container. The light source is arranged to emit light into the medicament container. The light is scattered by the medicament or medicament container and detected by the sensor. The sensor is connected to a processor unit for detecting the position of the stopper). | 10-25-2012 |
20120271242 | ASSEMBLY FOR USE IN A DRUG DELIVERY DEVICE - The present invention relates to an assembly for a drug delivery device comprising a dispensing container and a reservoir container for holding a fluid medicinal product, wherein the dispensing container and the reservoir container are connected to one another and are in fluid communication, and wherein the dispensing container is squeezable for dispensing a dose of the fluid medicinal product from the dispensing container, the dispensing container being refillable with the fluid medicinal product from the reservoir container. | 10-25-2012 |
20120291778 | MEDICAMENT CONTAINER - The invention relates to a medicament container for a liquid medicament. The medicament container comprises a deformable bag with an outlet and at least one deformation member consisting of a shape memory alloy. The at least one deformation member is arranged to deform the deformable bag when the shape memory alloy passes from a first phase into a second phase by a phase transition, thereby changing the shape of the deformation member and squeezing a dose of the medicament through the outlet out of the bag. | 11-22-2012 |
20150126928 | DRUG DELIVERY DEVICE - The invention relates to a drug delivery device, comprising a control unit, a drive unit, a pressurizing medium container arranged to contain a pressurizing liquid, a drug container arranged to contain a drug and a discharge nozzle, wherein the drive unit when controlled and energized by the control unit is arranged to generate a pressure gradient in the pressurizing liquid thereby propagating the pressure to the drug container and at least partially displacing the drug from the drug container through the discharge nozzle, wherein the drive unit is arranged as an electro-osmotic actor. | 05-07-2015 |
20150126940 | DRUG DELIVERY DEVICE - The invention relates to a drug delivery device, comprising:
| 05-07-2015 |
20150148745 | STOPPER ARRANGEMENT FOR A DRUG DELIVERY DEVICE - The invention relates to a stopper arrangement for a drug delivery device, comprising a stopper, a linear actor coupled with one end to the stopper and with an opposite end to a coupling arrangement, wherein the stopper arrangement is configured to be disposed within a container of a drug delivery device, wherein a shape and/or material of the stopper and the coupling arrangement are configured such that a first frictional force between the coupling arrangement and the container is lower than a frictional force between the stopper and the container when the linear actor is contracting and that second frictional force between the coupling arrangement and the container is greater than the frictional force between the stopper and the container when the linear actor is expanding. | 05-28-2015 |
20150174330 | ARRANGEMENT AND METHOD FOR DETERMINING A STOPPER POSITION - The invention relates to an arrangement for determining a position (x) of a stopper relative to a container in a drug delivery device, comprising an acoustic source configured to emit an acoustic signal and an acoustic sensor configured to detect an acoustic signal, a processing unit for controlling the acoustic source and processing the detected acoustic signal for determining characteristics of the acoustic signal correlated with the position (x) of the stopper. Furthermore, the invention relates to a method for determining a position (x) of a stopper relative to a container in a drug delivery device, the method comprising the steps of emitting an acoustic signal from an acoustic source, detecting an acoustic signal caused by the emitted acoustic signal by means of an acoustic sensor, and processing the detected acoustic signal for determining characteristics of the acoustic signal correlated with the position (x) of the stopper by means of a processing unit. | 06-25-2015 |
20150190569 | Drug Container and Drug Delivery Device - The invention relates to a drug container, comprising a flexible bag with a distal end connectable to a discharge nozzle, wherein the bag is compressible by a compression means, wherein the compression means is arranged as an axle attached to an opposite end of the bag and arranged to be rotated so as to spirally wind the bag about the axle. | 07-09-2015 |
Patent application number | Description | Published |
20110154253 | PROCESS FIELD EXTENSIBILITY FOR BUSINESS OBJECTS - A system and method for creating extension fields for business objects are described. In various embodiments, a system includes modules to display business processes and business objects thereof in graphical user interface screens. In various embodiments, the system propagates created extension fields to other business objects via metadata derived from selections in the graphical user interface. In various embodiments, a method for propagating extension fields from one business object to another business object via a data flow between the two business objects is presented. In various embodiments, the method receives instructions from a graphical user interface for the propagation of an extension field and sends instructions to a backend module to propagate the extension field from the source business object to the other business object. | 06-23-2011 |
20130127863 | DETERMINING AN OPTIMAL SEQUENCE OF STATUS TRANSITIONS FOR BUSINESS OBJECTS - Various embodiments of systems and methods for determining optimal an sequence of status transitions for business objects are described herein. In one aspect, the method executed by one or more computers in a network of computers includes receiving a target status for a business object, identifying a source status of the business object, identifying a status schema including one or more transitions from the source status to the target status, parsing the status schema to retrieve the one or more transitions from the source status to the target status, generating a graphical representation illustrating the transitions from the source status to the target status, executing an algorithm upon the graphical representation to determine an optimal sequence of transitions from the source status to the target status, and processing the business object based upon the optimal sequence of transitions to attain the target status. | 05-23-2013 |
20140006072 | Consistent Interface for Customer - Message Set 2 | 01-02-2014 |
20140006230 | Consistent Interface for Material | 01-02-2014 |
20140006291 | CONSISTENT INTERFACE FOR SERVICE PRODUCT | 01-02-2014 |
20140006307 | Consistent Interface for Customer - Message Set 3 | 01-02-2014 |
20140006492 | Consistent Interface for Entitlement Product | 01-02-2014 |
20140006520 | Consistent Interface for Customer - Message Set 1 | 01-02-2014 |
20140181020 | INTEGRATION SCENARIO FOR MASTER DATA WITH SOFTWARE-AS-A-SERVICE SYSTEM - According to one general aspect, a method may include replicating, to a software-as-a-service application, a plurality of pieces of master data from a physically remote master database. The method may also include converting the plurality of pieces of master data into one or more pieces of local data of the software-as-a-service application. The method may include changing one or more of either the pieces of master data or the pieces of local data. The method may further include synchronizing the changed pieces of either master data or local data between the remote master database and the software-as-a-service application. | 06-26-2014 |
20140201654 | SELF SERVICE PROPAGATION OF CUSTOM EXTENSION FIELDS INTO WEB SERVICES - Software solutions in a business software framework can expose their data via web services, which can readily provide access to all non-customized fields of objects included as part of the default installation of the software solution. However, customer-added extensions, such as for example custom fields and the like, added to customize the software solution for a specific business or business use can be difficult to add to web services by a typical business user who lacks technical abilities. Described herein are approaches to enabling addition of custom fields to web services via an intuitive interface that does not require technical understanding of the software solution, the business software framework, web services, etc. | 07-17-2014 |