Patent application number | Description | Published |
20110015865 | DETERMINATION OF CORONARY ARTERY DISEASE RISK - Markers and methods useful for assessing coronary artery disease in a subject are provided, along with kits for measuring their expression. Also provided are predictive models, based on the markers, as well as computer systems, and software embodiments of the models for scoring and optionally classifying samples. | 01-20-2011 |
20110184712 | PREDICTIVE MODELS AND METHODS FOR DIAGNOSING AND ASSESSING CORONARY ARTERY DISEASE - Biomarkers useful for diagnosing and assessing the extent of coronary artery disease (CAD) are provided, along with kits for measuring their expression. The invention also provides predictive models, based on the biomarkers, as well as computer systems, and software embodiments of the models for scoring and optionally classifying samples. In a preferred embodiment, the biomarkers are organized into clustered groups. The expression level of the biomarkers within a group are highly correlated to each other in normal and disease states. Expression values of genes chosen from each of two, three, four or five of the clustered gene groups, A, B, C, D, E may be used. Alternatively, expression values of genes chosen from the groups are combined into a metagene. Preferred biomarkers include S100A12, S100A8, S100A9, BCL2A1, and F5 (group A); XK, P62, and FECH (group B); TUBB2 (group C); IFNG, PDGFB, VSIG4, and TNF (group D); CSF3R, TLR5, CD46, and NCF1 (group E); S100A12, S100A9, BCL2A1, TXN and CSTA (group I); OLIG1, OLIG2, ADORA3, CLC, and SLC29A1 (group II); and CBS and ARG1 (group IV). | 07-28-2011 |
20140156198 | Determining Coronary Artery Disease Risk - Markers and methods useful for assessing coronary artery disease in a subject are provided, along with kits for measuring their expression. Also provided are predictive models, based on the markers, as well as computer systems, and software embodiments of the models for scoring and optionally classifying samples. | 06-05-2014 |
20150178462 | Methods and Compositions for Determining Smoking Status - Peripheral blood markers are provided whose expression levels correlate with smoking status. Predictive models developed using highly informative markers are disclosed, along with systems, kits, and methods for using the markers to provide a biochemical surrogate for a subject's smoking status. In some embodiments, the smoking-related disease is chronic obstructive pulmonary disease, chronic bronchitis, emphysema, lung cancer, and/or asthma. | 06-25-2015 |
Patent application number | Description | Published |
20080253150 | Flyback converter providing simplified control of rectifier MOSFETS when utilizing both stacked secondary windings and synchronous rectification - The present invention provides methods and systems for a flyback converter arranged with synchronous rectifier MOSFETS in such a manner that they operate with a common source potential while still providing for the use of a stacked output winding. With a common source potential, a single rectifier control voltage can be used to operate the rectifiers for multiple outputs greatly simplifying the control circuit. Advantageously, the present invention maintains the inherent simplicity of the flyback design while enabling designs with well-regulated multiple voltage outputs and the efficiency benefits of synchronous rectification. | 10-16-2008 |
20110176815 | MULTI-CHANNEL OPTICAL TRANSCEIVER WITH OFFSET QUADRATURE AMPLITUDE MODULATION - The present disclosure provides a multi-carrier optical transmitter, receiver, transceiver, and associated methods utilizing offset quadrature amplitude modulation thereby achieving significant increases in spectral efficiency, with negligible sensitivity penalties. In an exemplary embodiment, an optical transmitter includes circuitry configured to generate a plurality of optical subcarriers, a plurality of data signals for each of the plurality of subcarriers, and a plurality of modulator circuits for each of the plurality of subcarriers, wherein each of the plurality of modulator circuits includes circuitry configured to offset an in-phase component from a quadrature component of one of the plurality data signals by one-half baud period. | 07-21-2011 |
20110255870 | OPTICAL TRANSCEIVERS FOR USE IN FIBER OPTIC COMMUNICATION NETWORKS - The present disclosure provides a polarization multiplexed transceiver, including: a transmitter; a receiver; circuitry within the transmitter configured to insert pilot tones as a reference state of polarization for a polarization multiplexed signal; and circuitry within the receiver configured to de-multiplex the polarization multiplexed signal using the pilot tones. The transmitted signal is constructed in such a manner as to facilitate the division of the receiver processing between the analog and digital domains such that the implementation may be simultaneously both highly spectrally efficient and power efficient. | 10-20-2011 |
20120183092 | ANALOG CONTINUOUS TIME MATCHED PULSE SHAPING TRANSMITTER AND RECEIVER FILTERS - The present invention provides a transmission system, including: a transmitter including a transmitter filter; a receiver including a receiver filter; and a communicative coupling between the transmitter and the receiver; wherein the transmitter filter and the receiver filter are matched for noise reduction, and wherein the combined responses of the transmitter filter and the receiver filter satisfy the Nyquist criteria. Optionally, the transmitter filter includes a pulse shaping quasi digital finite impulse response filter. Optionally, the receiver filter includes an inductor-capacitor ladder based filter. | 07-19-2012 |
20130182585 | LINK MANAGEMENT SYSTEMS AND METHODS FOR MULTI-STAGE, HIGH-SPEED SYSTEMS - A system includes a plurality of modules, a backplane communicatively coupled to the plurality of modules, a plurality of links defined between the plurality of modules over the backplane, and a link management system configured to dynamically manage parameters associated with each of the plurality of links A link management method includes, for a system, defining a codebook for each module, device, and interconnect in the system, the codebook includes data describing physical link topologies and configuration parameters associated therewith, for initializing a link in the system, obtaining appropriate codebooks for each segment in the link, calculating an overall link loss for the link based on data in the appropriate codebooks, and obtaining configuration parameters for the link based on the overall link loss. | 07-18-2013 |
20130287398 | MULTI-CHANNEL OPTICAL TRANSCEIVER WITH OFFSET QUADRATURE AMPLITUDE MODULATION - The present disclosure provides a multi-carrier optical transmitter, receiver, transceiver, and associated methods utilizing offset quadrature amplitude modulation thereby achieving significant increases in spectral efficiency, with negligible sensitivity penalties. In an exemplary embodiment, an optical transmitter includes circuitry configured to generate a plurality of optical subcarriers, a plurality of data signals for each of the plurality of subcarriers, and a plurality of modulator circuits for each of the plurality of subcarriers, wherein each of the plurality of modulator circuits includes circuitry configured to offset an in-phase component from a quadrature component of one of the plurality data signals by one-half baud period. | 10-31-2013 |
20140117774 | POWER FEED ENTRY CIRCUIT FOR TELECOMMUNICATION APPLICATIONS - A power feed entry circuit, a module with the power feed entry circuit, and a daughter board with the power feed entry circuit include a first circuit coupled to inputs and outputs, wherein the first circuit is configured for power connections, return isolation relays, diode Or-ing, and output status-indication light-emitting diodes (LEDs); a second circuit coupled to the first circuit, the inputs, and the outputs, wherein the second circuit is configured with a hot swappable controller and provides common-mode and differential mode power line filtering; a third circuit coupled to the first circuit, wherein the third circuit is configured for alarm monitoring of the first circuit and the second circuit; and a fourth circuit coupled to the first circuit and the third circuit, wherein the fourth circuit comprises a dual feed high and low active field effect transistor Or-ing circuit. | 05-01-2014 |
Patent application number | Description | Published |
20150312128 | DATA PROCESSING - Measures for processing data in a packet-switched network. A first device is configured to snoop control packets of a predetermined control plane protocol in the network. The predetermined control plane protocol is operated by a plurality of other devices in the network to obtain Layer 2 information on the basis of known Layer 3 information. The first device does not operate the predetermined control plane protocol in the network. At the first device, in response to identifying that a given snooped packet was generated according to the predetermined control plane protocol. Layer 3 information associated with a second device in the plurality is extracted from the given snooped control plane protocol packet on the basis of known Layer 2 information associated with the second device. The second device is connected to the first device. | 10-29-2015 |
20150312129 | DATA PROCESSING - Measures for processing data in a packet-switched network. At a first device in the network, an echo request packet is transmitted into the network. The echo request packet comprises a predetermined identifier. An echo response packet is received from a second device in the network. In response to the received echo response packet comprising the predetermined identifier, the received echo response packet is identified as a packet generated on the basis of an echo request packet originated from the first device, and an Internet Protocol (IP) address comprised in the received echo response packet is determined to be an IP address of the second device. | 10-29-2015 |
20150312149 | DATA PROCESSING - Measures for processing data in a packet-switched network. At a first device in the network, a packet transmitted from a second device in the network is received. The received packet comprising an Internet Protocol (IP) address for a third device in the network. On the basis of the IP address for the third device comprised in the received data packet, lookup in an IP routing table of the second device is initiated to obtain a next-hop address for the received packet. The obtained next-hop IP address is determined to be an IP address of a device connected to the first device. | 10-29-2015 |