Patent application number | Description | Published |
20110079614 | FLUID PRODUCT DISPENSER - A dispenser includes a housing holding an assembly, including a liquid reservoir, a pump for dispensing the fluid product, and an outlet nozzle. The pump includes a liquid chamber for containing a dose of the liquid product and a pressurizing device which allows liquid product to be drawn into or expelled from the liquid chamber. The dispenser further includes a shunting chamber including a first aperture allowing flow access to the reservoir, a second aperture allowing flow access to the outlet nozzle, and a third aperture allowing flow access to the liquid chamber. The third aperture is disposed off-axis with respect to the first and second apertures. The shunting chamber further includes a mechanically actuated governing device that has two states, one defining a flow path between the first and third apertures and one defining a flow path between the third and second apertures. | 04-07-2011 |
20140189992 | FLUIDIC PRODUCT DISPENSER - A dispenser includes a housing holding an assembly, including a liquid reservoir, a pump for dispensing the fluid product, and an outlet nozzle. The pump includes a liquid chamber for containing a dose of the liquid product and a pressurizing device which allows liquid product to be drawn into or expelled from the liquid chamber. The dispenser further includes a shunting chamber including a first aperture allowing flow access to the reservoir, a second aperture allowing flow access to the outlet nozzle, and a third aperture allowing flow access to the liquid chamber. The third aperture is disposed off-axis with respect to the first and second apertures. The shunting chamber further includes a mechanically actuated governing device that has two states, one defining a flow path between the first and third apertures and one defining a flow path between the third and second apertures. | 07-10-2014 |
20150059176 | FLUID PRODUCT DISPENSER - A method of maintaining a fluid dispenser that includes a housing holding an assembly, including a liquid reservoir, a pump for dispensing the fluid product, and an outlet nozzle includes disconnecting the a compressor portion of the pump and substituting the disconnected compressor by a replacement compressor, wherein the replacement compressor has a different pressurizing volume to the replaced compressor. | 03-05-2015 |
Patent application number | Description | Published |
20080226722 | Gel Composition Comprising Charged Polymers - Aqueous gel compositions are disclosed which are useful as drug carriers for controlled delivery applications, such as for parenteral depot formulations. The gels comprise ionically charged microparticles, and preferably mixtures of oppositely charged microparticles. The microparticles can be loaded with active compounds, such as therapeutic peptides and proteins. The gels can be prepared by combining oppositely charged microparticles in the presence of water. | 09-18-2008 |
20100255098 | STEREOCOMPLEX HYDROGELS - The invention relates to hydrogel compositions, which can be applied as biodegradable materials and to the processes to prepare such hydrogels. The hydrogel of the present invention comprises a stereocomplex gel structure which is the result of the interaction of oligomerized monomers of one chirality with that of oligomerized monomers of the opposite chirality, both grafted to hydrophilic polymers. The grafts form an interaction which is different from a covalent chemical interaction and thus provide the gel with the required coherence. | 10-07-2010 |
20110217448 | METHOD FOR PREPARATION OF A CONTROLLED RELEASE SYSTEM - The present invention relates to a method for the preparation of a controlled release system and especially to a method for entrapment of compounds in polymer carriers for controlled release of active ingredients, preferably bioactive ingredients, such as drugs. This method results in a system for controlled release of active ingredients and especially for controlled drug delivery. In accordance with the present invention, the tem controlled release ” encompasses all kinds of controlled release, including slow release, sustained and delayed release. Particularly, the present invention results in active ingredients, entrapped in or otherwise incorporated in or coupled to polymer carriers or polymeric devices, such as micelles, nanoparticles, microspheres and other types of polymer devices for controlled release; the active ingredients are covalently bonded to the polymer carriers or polymeric devices. | 09-08-2011 |
20120015034 | TEMPERATURE SENSITIVE POLYMERS - The present invention relates to compositions comprising polymers whose solubility characteristics can be changed by incubation and particularly poly (hydroxyalkyl(meth) acrylamide mono/di-lactate interpolymers. Another aspect of this invention is the application of such temperature sensitive polymers as release systems of biologically active compounds. The polymers of the present invention comprise monomers, which have modifiable functionality. The functionality of the monomers can for example be modified by the presence of hydrolysable groups. The modification is effected by the incubation, leading to a change of the water solubility characteristics of the polymer. The polymers used in the present invention contain hydrolysable chemical groups. As a result the polymer's solution characteristics, specifically its lower critical solution temperature (LCST), change upon incubation. | 01-19-2012 |
Patent application number | Description | Published |
20130261094 | TUNABLE, BIODEGRADABLE LINKER MOLECULES FOR TRANSIENT CONJUGATION OF COMPONENTS IN DRUG DELIVERY SYSTEMS, AND DRUG DELIVERY SYSTEMS PREPARED THEREWITH - The present invention relates to a particular class of biodegradable linkers, ensuring transiently stable conjugation of building blocks and/or bioactive compounds into drug delivery systems (DDS), such as DDS based on polymeric micelles or hydrogels. In addition, the present invention relates to compounds, comprising said linkers, such compounds preferably being prodrugs. Further, the invention is directed to the use of said linkers, and especially said biodegradable linkers, in a drug delivery system. Moreover, the invention relates to controlled release system comprising a polymer matrix, capable of releasing an active ingredient, wherein the active ingredient is covalently linked to the polymer molecules of the polymer matrix through said linkers, as well as to a method of synthesising these linkers and preparing such controlled release systems. | 10-03-2013 |
20140235799 | METHOD FOR PREPARATION OF A CONTROLLED RELEASE SYSTEM - The present invention relates to a method for the preparation of a controlled release system and especially to a method for entrapment of compounds in polymer carriers for controlled release of active ingredients, preferably bioactive ingredients, such as drugs. This method results in a system for controlled release of active ingredients and especially for controlled drug delivery. In accordance with the present invention, the term “controlled release” encompasses all kinds of controlled release, including slow release, sustained and delayed release. Particularly, the present invention results in active ingredients, entrapped in or otherwise incorporated in or coupled to polymer carriers or polymeric devices, such as micelles, nanoparticles, microspheres and other types of polymer devices for controlled release; the active ingredients are covalently bonded to the polymer carriers or polymeric devices. | 08-21-2014 |