Whitacre
David C. Whitacre, San Diego, CA US
Patent application number | Description | Published |
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20160022801 | RODENT HEPADNAVIRUS CORES WITH REDUCED CARRIER-SPECIFIC ANTIGENICITY - The present disclosure generally relates to hepadnavirus core antigens in which one or more endogenous b cell epitopes have been effectively removed. More specifically, the present disclosure relates to rodent hepadnavirus cores modified to diminish the antibody response to the core so as to enhance the antibody response to heterologous polypeptides included therein. | 01-28-2016 |
20160039883 | PALIVIZUMAB EPITOPE-BASED VIRUS-LIKE PARTICLES - The present disclosure generally relates to immunogens for eliciting an antibody response against respiratory syncytial virus (RSV). More specifically, the present disclosure relates to virus-like particles (VLPs) including a RSV F protein epitope, as well as methods of use thereof. Respiratory syncytial virus (RSV) is a major cause of lower respiratory tract disease in infants and young children (Hall et al., NEJM, 360:5888-598, 2009; and Nair et al., Lancet, 375:1545-1555, 2010) and a vaccine to protect this young population is of high priority. | 02-11-2016 |
Donald Whitacre, Ann Arbor, MI US
Patent application number | Description | Published |
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20110204587 | SERVICE LOAD BEARING ASSEMBLY FOR SPREADING OUT HIGH INDUCED STRESSES - Embodiments of the present invention provide a suspension assembly including a bolt made from a bolt material; a suspension component made from a suspension material, the suspension component having a suspension opening therethrough, the suspension opening having a geometry for insertion of at least a first portion of the bolt; and a bushing assembly including an elastomeric element and a bushing opening therethrough, the bushing opening having a geometry for insertion of at least a second portion of the bolt; wherein the suspension material has a yield strength that is substantially higher than a yield strength of the bolt material, | 08-25-2011 |
Micah Whitacre, Olathe, KS US
Patent application number | Description | Published |
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20150302147 | Synchronization of Heatlhcare Data Across Disparate Data Centers - Methods, systems, and computer-readable media are provided for synchronizing healthcare data across disparate data centers. Healthcare data from healthcare data sources is received by a collector service that operates in a cloud computing platform. The data is sent to a staging platform associated with a first data center that is hosting the collector service. From here, the data is stored in association with a long-term storage data store associated with the first data center. As well, it is communicated to processing nodes associated with the first data center that subscribe to the data. The staging platform also communicates the data to a staging platform associated with a second data center. This staging platform also stores the data in association with a long-term storage data store located at the second data center and communicates the data to processing nodes located at the second data center that subscribe to the data. | 10-22-2015 |
20150302149 | AGGREGATION, PARTITIONING, AND MANAGEMENT OF HEALTHCARE DATA FOR EFFICIENT STORAGE AND PROCESSING - Methods, systems, and computer-readable media are provided for aggregating, partitioning, and storing healthcare data. Healthcare data is collected from various disparate healthcare data sources. The data is aggregated into batches of the same type of data. From here, the data is partitioned according to the data's originating healthcare data source. The aggregated and partitioned healthcare data is then stored in a long term storage data store. This system of storing healthcare data allows for efficient retrieval and processing by computing solutions that need access to batches of healthcare data. The system also reduces costs associated with storing data as duplicate storage is eliminated. | 10-22-2015 |
Micah K. Whitacre, Olathe, KS US
Patent application number | Description | Published |
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20150332010 | RULE-BASED LOW-LATENCY DELIVERY OF HEALTHCARE DATA - Methods, systems, and computer-readable media are provided for delivering healthcare records with low latency. Healthcare data is collected from various disparate healthcare data sources. The data is filtered in accordance with routing rules to identify healthcare data to deliver to a processing node. The routing rules specify that healthcare data from a particular originating source of a particular data type is to be delivered to a particular processing node. The healthcare data is converted to a local format for use by a computing solution. This system of delivering healthcare data with low latency ensures that the data is delivered to the correct location in the correct format, even if the routing rules change. | 11-19-2015 |
Tim Whitacre, Paso Robles, CA US
Patent application number | Description | Published |
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20140354444 | CHANNEL IMPULSE RESPONSE IDENTIFICATION AND COMPENSATION - A method of interpreting a signal transmitted through a drilling fluid disposed within a telemetry channel of a wellbore that includes defining a finite number of distinct message signals for representing conditions within the wellbore. The method also includes transmitting one of the message signals through the telemetry channel, and receiving a distorted signal that includes the message signal as distorted by transmission through the telemetry channel. A channel impulse response is estimated and applied to at least one of the message signals to generate at least one predicted signal. A comparison is made between the predicted signal and the distorted signal, and an estimation is made as to which of the finite number of message signals is included in the distorted signal based on the comparison. | 12-04-2014 |
20150345287 | DOWNHOLE MWD SIGNAL ENHANCEMENT, TRACKING, AND DECODING - A method for transmitting data from a MWD system at the BHA of a drill string may include transmitting the data in a MWD signal from the MWD system. The MWD signal may be modulated at a position closer to the surface onto a mud pulse modulated signal. The mud pulse modulated signal may be generated by a downhole friction reducing device. The downhole friction reducing device may include a mud motor. The mud motor may create pressure pulses based on its speed of rotation. The downhole friction reducing device may include a modulating valve. The modulating valve may be electromechanically or mechanically operated. The modulated signal may be detected at the surface by a receiver using one or more pressure or flow sensors. The receiver may use one or more harmonics of the modulated signal to receive the data. | 12-03-2015 |
William Whitacre, Cambridge, MA US
Patent application number | Description | Published |
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20160055124 | SYSTEMS AND METHODS FOR LOW-RANK MATRIX APPROXIMATION - Systems and methods for generating a low-rank approximation of a matrix are provided. The various systems and methods may identify at least a first set of right singular vectors and a first set of singular values of a subset of the matrix, reduce the subset by an amount of energy of a selected data entry of the subset based on the first set of right singular vectors and the first set of singular values, incorporate a new data entry from the matrix into the subset, update the first set of right singular vectors and the first set of singular values of the subset based on the new data entry by a singular value decomposition (SVD) update, and generate the low-rank approximation of the matrix based on the updated first set of right singular vectors and the updated first set of singular values. | 02-25-2016 |