Patent application number | Description | Published |
20090042869 | SIGNAL-DEPENDENT SPLICING OF TISSUE FACTOR PRE-mRNA IN PLATELET CELLS - The invention relates to therapeutic target recognition, development, and validation of a compound capable of directly or indirectly modulating TF pre-mRNA splicing in a platelet cell and the use of a platelet TF pre-mRNA splicing modulator for the treatment of a subject suffering from, or thought to be suffering from, disordered coagulation. | 02-12-2009 |
20100297621 | USE OF PRE-MRNA SPLICING IN PLATELET CELLS FOR THE DIAGNOSIS OF DISEASE - The invention relates to materials and procedures for identifying or using tissue factor (TF) pre-mRNA splicing, CIk 1 activity or TF-dependent coagulation in platelet cells for the diagnosis, prognosis, or prediction of a disease or disorder associated with disordered coagulation. Since activated platelets splice pre-mRNAs to generate inflammatory and thrombotic mediators that contribute to diseases such as sepsis and septic shock, (TF) pre-mRNA splicing in platelets is an indicator of inflammatory and thrombotic disease states. TF pre-mRNA splicing in platelets is correlated with sepsis, increased age (≧65), APACHE II score, and bacteremia. Thus, TF mRNA expression patterns in platelets may be used for the diagnosis, prognosis, or prediction of a disease or disorder associated with disordered coagulation, for example, patients that are at a higher risk for severe sepsis, organ failure, and death. | 11-25-2010 |
20110294737 | TERMINALLY-DIFFERENTIATED ANUCLEATE PLATELET PROGENY GENERATION - Platelets are induced to proliferate, form extensions and produce daughter cells by various methods, including culturing platelets under thrombocytopenic conditions. Expansion of platelet cell numbers increases the storage life of platelets. Modulation of RT activity can be used to produce new daughter platelets. Therefore, the invention provides a new therapeutic use for RT inhibitors that can now be used for treatment of thrombocytopenia and related disorders. Likewise, application of soluble protein factor that may be secreted and/or released by platelets cultured under thrombocytopenic conditions may also be used as a therapeutic agent to increase platelet numbers. | 12-01-2011 |
20140099634 | USE OF PRE-MRNA SPLICING IN PLATELET CELLS FOR THE DIAGNOSIS OF DISEASE - The invention relates to materials and procedures for identifying or using tissue factor (TF) pre-mRNA splicing, Clk 1 activity or TF-dependent coagulation in platelet cells for the diagnosis, prognosis, or prediction of a disease or disorder associated with disordered coagulation. Since activated platelets splice pre-mRNAs to generate inflammatory and thrombotic mediators that contribute to diseases such as sepsis and septic shock, (TF) pre-mRNA splicing in platelets is an indicator of inflammatory and thrombotic disease states. TF pre-mRNA splicing in platelets is correlated with sepsis, increased age (≧65), APACHE II score, and bacteremia. Thus, TF snRNA expression patterns in platelets may be used for the diagnosis, prognosis, or prediction of a disease or disorder associated with disordered coagulation, for example, patients that are at a higher risk for severe sepsis, organ failure, and death. | 04-10-2014 |
Patent application number | Description | Published |
20100207367 | Airbag device for protecting a vehicle occupant - An airbag device for protecting a vehicle occupant in case of a crash, including at least one region that can be inflated with gas, which in the inflated state forms a gas cushion for a vehicle occupant to be protected in the form of a side airbag, at least a first material layer of the inflatable region extending in front of a lateral vehicle structure of a motor vehicle in the inflated state of the airbag device, and at least a second material layer of the inflatable region of the inflatable region, that opposes the first material layer in the inflated state of the airbag device, wherein at least one fastening flap is provided at the airbag device via which the airbag device can be fastened to a motor vehicle structure. | 08-19-2010 |
20100207368 | Airbag midule - An airbag module including an airbag, an airbag covering, that defines an interior space of the airbag, that can be filled with gas for inflating the airbag, a gas generator for providing the gas needed for inflating the airbag, an insertion opening of the airbag covering, wherein the gas generator is inserted through the insertion opening into the interior space of the airbag, so that gas provided by the gas generator enters the interior space of the airbag, a boundary region of the insertion opening delimiting the insertion opening, which boundary region annularly encompasses the gas generator, and a sealing means for sealing the insertion opening. The sealing means is arranged between the boundary region and the gas generator so that the sealing means is widened by the gas provided by the gas generator and pressed against the boundary region of the insertion opening for sealing the insertion opening. | 08-19-2010 |
20110169250 | VEHICLE SEAT ARRANGEMENT AND AIRBAG ARRANGEMENT FOR A MOTOR VEHICLE AND A METHOD FOR PROTECTING A VEHICLE OCCUPANT - A vehicle seat arrangement for a motor vehicle is provided. The vehicle seat arrangement comprising a vehicle seat, which comprises at least one inflatable element for protecting a vehicle occupant residing on the vehicle seat. The inflatable element is formed and arranged such that said element expands predominantly in direction towards the vehicle occupant when inflated. The inflatable element is integrated into a backrest of the vehicle seat unfolded or provided with only one fold or a protuberance, wherein the inflatable element is arranged between a cushion of the vehicle seat and a cover of the vehicle seat or inside the cushion. | 07-14-2011 |
20120306186 | AIRBAG FOR A VEHICLE PASSENGER-PROTECTING SYSTEM AND A METHOD FOR PRODUCING THE SAME - An airbag device for a vehicle passenger-protecting system. According to one variant, the airbag device comprises a first airbag segment, which has at least two material blanks and a second airbag segment which has at least two material blanks, wherein the material blanks of the first airbag segment and the material blanks of the second airbag segment are connected to one another at the respective circumferential edge in a gas-tight manner. The first airbag segment has a first transitional section and the second airbag segment has a second transitional section, wherein the transitional sections form a transitional region in which the two airbag segments are connected to one another in a gas-tight manner. An opening can be formed in each of the two transitional sections. | 12-06-2012 |
Patent application number | Description | Published |
20130027196 | OBSTACLE DETECTION SYSTEM - A computer-implemented method of detecting objects in a path of a vehicle is provided. An image frame that depicts the path of the vehicle is obtained. An edge-image corresponding to the image frame is generated. A binary image corresponding to the edge-image is also generated. One or more blobs in the binary image that respectively correspond to one or more objects in the image frame are identified. Based on an analysis of the blobs in the binary image, a determination is made that one of the objects in the image frame is an obstacle in the path of the vehicle. | 01-31-2013 |
20130070095 | FAST OBSTACLE DETECTION - Systems and methods for detecting obstacles using a single camera positioned on an apparatus in motion over an area of motion, or stationary over a moving area of motion. In an example method, a video stream of images is captured of the area of motion. The images in the video stream may be corrected for lens distortion prior to further processing. An Nth image frame is selected from a sequence of N images in the video stream. A set of N−1 difference images is calculated by subtracting each of the N−1 previous images from the Nth image. The N−1 difference images are added to one another to generate a combined difference image. A perspective transformation is performed on the combined difference image to generate a transformed image. The transformed image is analyzed to detect edges of obstacles in the transformed image. A signal indicating detection of an obstacle in the area of motion may then be generated. | 03-21-2013 |
20130070962 | EGOMOTION ESTIMATION SYSTEM AND METHOD - A computer-implemented method for determining an egomotion parameter using an egomotion estimation system is provided. First and second image frames are obtained. A first portion of the first image frame and a second portion of the second image frame are selected to respectively obtain a first sub-image and a second sub-image. A transformation is performed on each of the first sub-image and the second sub-image to respectively obtain a first perspective image and a second perspective image. The second perspective image is iteratively adjusted to obtain multiple adjusted perspective images. Multiple difference values are determined that respectively correspond to the respective difference between the first perspective image and the adjusted perspective images. A translation vector for an ego motion parameter is determined. The translation vector corresponds to one of the multiple difference values. | 03-21-2013 |
20130162826 | METHOD OF DETECTING AN OBSTACLE AND DRIVER ASSIST SYSTEM - To detect an obstacle in a single image captured using a single image sensor of a driver assist system, at least one image feature is established in the single image which extends along a line passing through a projection point of the image sensor. At least one line extending along a direction normal to a road surface in the world coordinate system is thereby identified based on the single image, which is used as a signature for an obstacle. | 06-27-2013 |
20130293678 | VIRTUAL NAVIGATION SYSTEM FOR VIDEO - System and method for adjusting the parameters of an image capturing device, such as a camera that captures a sequence of images and generates another image from the captured sequence of images using parameters that identify a virtual location and overlaying the generated image with a 3D generated image where distortion compensation has occurred been applied to the image. | 11-07-2013 |
20130293683 | SYSTEM AND METHOD OF INTERACTIVELY CONTROLLING A VIRTUAL CAMERA - A multiple-view virtual camera system comprising one or more image source units, an image processing unit, a parameter setting unit in signal communication with the image processing unit, and a display in signal communication with the image processing unit. The display is configured to display images generated by the image processing unit to a user of the virtual camera system, where the displayed images are configured according to image-related parameters input by a user of the multiple-view camera system through the parameter setting unit. The parameter setting unit may include a user interface, such as a single-touch or multi-touch touchscreen display, configured to accept input from the user that adjusts the parameters that are transmitted to the image processing unit and utilized by the image processing unit. A method of interactively controlling the virtual camera system by a user of a motor vehicle is also disclosed. | 11-07-2013 |
20150294167 | METHOD AND SYSTEM FOR DETECTING TRAFFIC LIGHTS - A method for detecting traffic lights is provided. The method includes: obtaining a color image captured by a camera; converting the color image into a first monochrome scale image; converting the first monochrome scale image into a first binary image; identifying a first set of candidate blobs in the first binary image based on at least one predetermined geometric parameter; and determine whether a first region in the color image, which first region corresponds to one of the first set of candidate blobs, is a green traffic light using a green traffic light classifier. The accuracy and efficiency may be improved. | 10-15-2015 |
20150332089 | SYSTEM AND METHOD FOR DETECTING PEDESTRIANS USING A SINGLE NORMAL CAMERA - The present application provides pedestrian detection system and method. A pedestrian detection method includes: obtaining an image captured by a camera; identifying a pedestrian candidate in the image; transforming the image into a top view image; calculating the actual height of the pedestrian candidate based on the top view image and extrinsic parameters of the camera; and determining whether the pedestrian candidate is a true positive by determining whether the actual height of the pedestrian candidate is within a predetermined pedestrian height range. The system and method of the present application have lower cost and higher accuracy compared with conventional technologies. | 11-19-2015 |
20150334301 | SYSTEM AND METHOD FOR GENERATING A SURROUND VIEW - A method and system for generating a surround view are provided. The method may include: establishing a surround surface; obtaining a plurality of images of surroundings; and projecting the images onto the surround surface based on a projection relationship between points on the surround surface and pixels on the images to generate a surround view, where the projection relationship may change with heights of the points on the surround surface. An improved projection effect may be obtained. | 11-19-2015 |