Weng, US
Binbin Weng, Norman, OK US
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20140252529 | Pb-salt Mid-infrared Detectors and Method for Making Same - The disclosure describes methods for preparing lead salt materials which are sensitive to the mid-infrared spectrum which can be used to manufacture high-uniformity, high-detectivity, polycrystalline lead salt photoconductive and photovoltaic photodetectors. | 09-11-2014 |
20160111567 | Photovoltaic Lead-Salt Detectors - Disclosed is at least one embodiment of an infrared (IR) photovoltaic (PV) detector, comprising a IV-VI Lead (Pb)-salt layer disposed on a substrate and a charge-separation-junction (CSJ) structure associated with the IV-VI Pb-salt layer, wherein the CSJ structure comprises a plurality of element areas disposed upon or within the IV-VI Pb-salt layer, wherein the plurality of element areas are spaced apart from each other. Each element area may be connected to a first Ohmic contact thereby forming a plurality of interconnected first Ohmic contacts, and a second Ohmic contact may be disposed upon a portion of the IV-VI Pb-salt layer. In another non-limiting embodiment, a PV detector, comprising a heterojunction region that comprises at least one IV-VI Pb-salt material layer coupled to at least one non-Pb-salt layer, wherein the at least one IV-VI Pb-salt layer and the at least one non-Pb-salt layer form a p-n junction or Schottky junction with a type II band gap alignment. | 04-21-2016 |
20160111579 | Photovoltaic Lead-Salt Detectors - Disclosed is at least one embodiment of an infrared (IR) photovoltaic (PV) detector, comprising a IV-VI Lead (Pb)-salt layer disposed on a substrate and a charge-separation-junction (CSJ) structure associated with the IV-VI Pb-salt layer, wherein the CSJ structure comprises a plurality of element areas disposed upon or within the IV-VI Pb-salt layer, wherein the plurality of element areas are spaced apart from each other. Each element area may be connected to a first Ohmic contact thereby forming a plurality of interconnected first Ohmic contacts, and a second Ohmic contact may be disposed upon a portion of the IV-VI Pb-salt layer. In another non-limiting embodiment, a PV detector, comprising a heterojunction region that comprises at least one IV-VI Pb-salt material layer coupled to at least one non-Pb-salt layer, wherein the at least one IV-VI Pb-salt layer and the at least one non-Pb-salt layer form a p-n junction or Schottky junction with a type II band gap alignment. | 04-21-2016 |
Binwei Weng, Andover, MA US
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20160135706 | Medical Premonitory Event Estimation - A system and method for medical premonitory event estimation includes one or more processors to perform operations comprising: acquiring a first set of physiological information of a subject, and a second set of physiological information of the subject received during a second period of time; calculating first and second risk scores associated with estimating a risk of a potential cardiac arrhythmia event for the subject based on applying the first and second sets of physiological information to one or more machine learning classifier models, providing at least the first and second risk scores associated with the potential cardiac arrhythmia event as a time changing series of risk scores, and classifying the first and second risk scores associated with estimating the risk of the potential cardiac arrhythmia event for the subject based on the one or more thresholds. | 05-19-2016 |
Binwei Weng, Chelmsford, MA US
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20150238101 | VCG VECTOR LOOP BIFURCATION - A system for determining T wave bifurcation that includes three or more ECG leads configured to receive an ECG signal and a first computing device including a processor coupled to a memory, the processor and the memory configured to perform operations including: generating at least two orthogonal ECG vectors based on the ECG signal of a patient, processing the at least two orthogonal ECG vectors to determine a loop trajectory of at least a portion of the ECG signal, identifying a trajectory bifurcation by comparing the loop trajectory to a control loop trajectory for a plurality of cardiac cycles, and determining an indicator of a cardiac event based on the trajectory bifurcation. | 08-27-2015 |
Binwei Weng, Boulder, CO US
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20130138002 | SYSTEMS AND METHODS FOR DETECTING ARRHYTHMIA FROM A PHYSIOLOGICAL SIGNAL - Arrhythmia may impact the determination of physiological information from a physiological signal. A patient monitoring system may detect the presence of arrhythmia based on changes in the physiological signal. Derived value data sets may be extracted from the physiological signal and calculations performed to generate arrhythmia features. The arrhythmia features may be used to generate an arrhythmia indicator that may indicate the presence of arrhythmia in the physiological signal. | 05-30-2013 |
20140243621 | SYSTEMS AND METHODS FOR DETECTING ARRHYTHMIA FROM A PHYSIOLOGICAL SIGNAL - Arrhythmia may impact the determination of physiological information from a physiological signal. A patient monitoring system may detect the presence of arrhythmia based on changes in the physiological signal. Derived value data sets may be extracted from the physiological signal and calculations performed to generate arrhythmia features. The arrhythmia features may be used to generate an arrhythmia indicator that may indicate the presence of arrhythmia in the physiological signal. | 08-28-2014 |
Binwel Weng, Boulder, CO US
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20130079657 | SYSTEMS AND METHODS FOR DETERMINING RESPIRATION INFORMATION FROM A PHOTOPLETHYSMOGRAPH - A signal representing physiological information may include information related to respiration. A patient monitoring system may utilize a wavelet transform to generate a scalogram from the signal. A threshold for the scalogram may be calculated, and scalogram values may be compared to the threshold. One of the scales meeting the threshold may be selected as representing respiration information such as respiration rate. The respiration information may be determined based on the selected scale. | 03-28-2013 |
Caihao Weng, Ann Arbor, MI US
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20150066406 | ON-BOARD STATE OF HEALTH MONITORING OF BATTERIES USING INCREMENTAL CAPACITY ANALYSIS - A method is provided for determining capacity of a battery. The method includes: defining a model for a battery, where the model relates terminal voltage of the battery to charged capacity of the battery; taking a plurality of voltage measures of the battery, where the voltage measures are taken through a range of states of charge and the range excludes the battery being fully charged and fully discharged; determining the parameters of the model by fitting the plurality of voltage measures to the model; determining an incremental capacity curve for the battery by taking derivative of the model; and quantifying a peak of the incremental capacity curve to thereby determine a capacity of the battery. | 03-05-2015 |
Chao Weng, Atlanta, GA US
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20150269933 | MIXED SPEECH RECOGNITION - The claimed subject matter includes a system and method for recognizing mixed speech from a source. The method includes training a first neural network to recognize the speech signal spoken by the speaker with a higher level of a speech characteristic from a mixed speech sample. The method also includes training a second neural network to recognize the speech signal spoken by the speaker with a lower level of the speech characteristic from the mixed speech sample. Additionally, the method includes decoding the mixed speech sample with the first neural network and the second neural network by optimizing the joint likelihood of observing the two speech signals considering the probability that a specific frame is a switching point of the speech characteristic. | 09-24-2015 |
Chao Jing Weng, Alexandria, LA US
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20140179209 | Bulk Meat Cutting Apparatus - A product for quickly cutting large quantities of meat into similarly sized pieces includes a cutting board, a hollow enclosure, and a top inserting press. The cutting board serves as a bottom surface for the hollow enclosure. The hollow enclosure is filled with food that needs to be cut, like raw chicken, after which the top inserting press is used to press the food down. The hollow enclosure has slits cut into each wall, with paired walls having matching slits. These slits run from top to bottom and allow a knife to cut through food held in the hollow enclosure. The slits are equally spaced from each other, resulting in food that is cut into equal pieces. The product is designed to allow a person to quickly cut large amounts of meat. The product is also intended to be easy to set up, use, and sanitize. | 06-26-2014 |
Chuan Weng, Cumming, GA US
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20130091876 | TEMPERATURE CONTROL SYSTEM AND METHOD FOR A CHAMBER OR PLATFORM AND TEMPERATURE-CONTROLLED CHAMBER OR PLATFORM INCLUDING THE TEMPERATURE CONTROL SYSTEM - A temperature control system and method include a source of a temperature control medium that is to be introduced into a space. A fluid line conveys the temperature control medium from the source to the space, a first end of the fluid line being disposed in the space. An orifice assembly has an orifice through which the cooling medium flows toward the space. A size of the orifice is adjustable such that a rate of flow of the cooling medium entering the space is controllable. | 04-18-2013 |
Da Feng Weng US
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20100231184 | Step up and down switching power converter's output current detect and control scheme - The invention presents a simple and high accuracy output current detect and control scheme to control the output current of the step up-down (Buck-Boost) and step up (Boost) switching converter, It makes step up-down (Buck-Boost) and step up (Boost) switching power converter operate in wide input voltage range and low in total BOM cost and the switching converter can be used as a controllable current source for several applications | 09-16-2010 |
20120306401 | LED dimming control scheme - In order to keep the advantage of PWM dimming control scheme and make the LED driver high reliability and the LED lamp long lifetime, it is required that the frequency of PWM dimming control scheme is related with or the same as the output frequency of existed dimmers; and the output PWM dimming pulse is covered by the output pulse from dimmers further. The present invention discloses a novel “LED dimming control” scheme to make that the frequency of PWM dimming control scheme is related with or the same as the output frequency of dimmers; and the output PWM dimming pulse is covered by the output pulse from the dimmers further. In this way, it can guarantee that as PWM dimming pulse comes, the output from the dimmer can offer enough power to the LED driver and the LED driver can output the required LED driving current without flicker. | 12-06-2012 |
David Weng, Malvern, PA US
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20140243276 | SMAC MIMETIC (BIRINAPANT) FOR USE IN THE TREATMENT OF PROLIFERATIVE DISEASES (CANCER) - A method of using a Smac mimetic and pharmaceutical compositions thereof. | 08-28-2014 |
Eric Hongzhao Weng, Pearland, TX US
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20140182307 | SYSTEM AND METHOD FOR EXPANDING A COMPRESSOR BLEED FLOW - A system includes a bleed system configured to direct a bleed flow from a high pressure region to a low pressure region. The bleed system includes a valve configured to control the bleed flow through the bleed system and a staged bleed conduit configured to incrementally depressurize the bleed flow. The staged bleed conduit includes an inlet coupled to the valve, a first stage configured to depressurize the bleed flow that is coupled to the inlet, a second stage configured to depressurize the bleed flow that is coupled to the first stage, and an outlet coupled to the second stage. The outlet is configured to direct the bleed flow to the low pressure region. The inlet, the first stage, the second stage, and the outlet are disposed along parallel axes. | 07-03-2014 |
Jiangang Weng, Canton, MI US
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20140160585 | FIRST SURFACE MIRROR, METHOD OF MAKING THE SAME, AND SCANNER AND/OR COPIER INCLUDING THE SAME - A first surface mirror including for example a substrate, a reflective layer (including aluminum, an aluminum alloy, silver, and/or a silver alloy), a dielectric layer, and an overcoat layer, a method of making the same, and a scanner and/or copier including the same are provided. | 06-12-2014 |
Jian-Gang Weng, Canton, MI US
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20140090687 | MULTIFUNCTIONAL STATIC OR SEMI-STATIC PHOTOVOLTAIC SKYLIGHT AND/OR METHODS OF MAKING THE SAME - Improved building-integrated photovoltaic systems according to certain example embodiments may include concentrated photovoltaic skylights or other windows having a cylindrical lens array. The skylight may include an insulated glass unit, which may improve the Solar Heat Gain Coefficient (SHGC). The photovoltaic skylight and lens arrays may be used in combination with strip solar cells. Arrangements that involve lateral displacement tracking systems, or static systems (e.g., that are fixed at one, two, or more predefined positions) are contemplated herein. Such techniques may advantageously help to reduce cost per watt related, in part, to the potentially reduced amount of semiconductor material to be used for such example embodiments. A photovoltaic skylight may permit diffuse daylight to pass through into an interior of a building so as to provide lighting inside the building, while the strip solar cells absorb the direct sunlight and convert it to electricity, providing for SHGC tuning. | 04-03-2014 |
Jian-Gang Weng, Corvallis, OR US
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20100089630 | Crossover - A crossover is formed by imprinting a channel, by depositing a first conductor in the channel, by anodizing a surface of the first conductor and by electroforming a second conductor across the first conductor. | 04-15-2010 |
Jian-Hui Weng, Oro Valley, AZ US
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20140094450 | BENZOIMIDAZOLE-CARBOXYLIC ACID AMIDE DERIVATIVES AS APJ RECEPTOR MODULATORS - The present invention relates to benzoimidazole-carboxylic acid amide compounds of the formula I, | 04-03-2014 |
Jinsheng Weng, Houston, TX US
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20140348902 | TCL1 PEPTIDES FOR IMMUNOTHERAPY - Provided are TCL1 peptides that bind to MHC I (HLA-A2) on tumor cells or other antigen-presenting cells and are recognized by T-cell receptors on T cells. The TCL1 peptides may be therapeutically used to treat a cancer, such as a B cell malignancy, leukemia, or lymphoma. Methods for expanding a population of T cells that target TCL1 are also provided. | 11-27-2014 |
Juvang Weng, Okemos, MI US
Juyang Weng, Okemos, MI US
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20140032461 | SYNAPSE MAINTENANCE IN THE DEVELOPMENTAL NETWORKS - The developmental neural network is trained using a synaptic maintenance process. Synaptogenic trimming is first performed on the neuron inputs using a synaptogenic factor for each neuron based on standard deviation of a measured match between the input and synaptic weight value. A top-k competition among all neurons then selects a subset of said neurons as winning neurons. Neuronal learning is applied only to these winning neurons, updating their synaptic weights and updating their synaptogenic factors. | 01-30-2014 |
20140258195 | Neuromorphic Spatiotemporal Where-What Machines - In various embodiments, electronic apparatus, systems, and methods include a unified compact spatiotemporal method that provides a process for machines to deal with space and time and to deal with sensors and effectors. Additional apparatus, systems, and methods are disclosed. | 09-11-2014 |
Ke Weng, Gaithersburg, MD US
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20100183628 | RANDOM HOMOZYGOUS GENE PERTURBATION (RHGP) WITH THERMAL ASSYMETRIC INTERLACED (TAIL)-PCR - A method for identifying host genes and encoded proteins for potential targets for therapeutic intervention employs a Gene Search Vector that is either lentivirus or MMLV-based, and can be used to interrogate an entire cell genome without prior knowledge of the genomic sequence. This Random Homozygous Gene Perturbation (RUGP) technique is rapidly verifiable and is used to identify potential host targets for intervention for influenza, HIV and other viral infections. Using Thermal Assymetric Interlaced (TAIL)-PCR, the period for identification of promising targets is reduced from months to weeks or less. Specific targets including PTCH1, Robo1 and Nedd4 are reviewed in detail. | 07-22-2010 |
20140271671 | RANDOM HOMOZYGOUS GENE PERTURBATION (RHGP) WITH THERMAL ASSYMETRIC INTERLACED (TAIL)-PCR - A method for identifying host genes and encoded proteins for potential targets for therapeutic intervention employs a Gene Search Vector that is either lentivirus or MMLV-based, and can be used to interrogate an entire cell genome without prior knowledge of the genomic sequence. This Random Homozygous Gene Perturbation (RUGP) technique is rapidly verifiable and is used to identify potential host targets for intervention for influenza, HIV and other viral infections. Using Thermal Assymetric Interlaced (TAIL)-PCR, the period for identification of promising targets is reduced from months to weeks or less. Specific targets including PTCH1, Robo1 and Nedd4 are reviewed in detail. | 09-18-2014 |
Lee Weng, Bellevue, WA US
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20090036774 | CONTROLLED HIGH EFFICIENCY LESION FORMATION USING HIGH INTENSITY ULTRASOUND - An ultrasound system used for both imaging and delivery high intensity ultrasound energy therapy to treatment sites and a method for treating tumors and other undesired tissue within a patient's body with an ultrasound device. The ultrasound device has an ultrasound transducer array disposed on a distal end of an elongate, relatively thin shaft. In one form of the invention, the transducer array is disposed within a liquid-filled elastomeric material that more effectively couples ultrasound energy into the tumor, that is directly contacted with the device. Using the device in a continuous wave mode, a necrotic zone of tissue having a desired size and shape (e.g., a necrotic volume selected to interrupt a blood supply to a tumor) can be created by controlling at least one of the f-number, duration, intensity, and direction of the ultrasound energy administered. This method speeds the therapy and avoids continuously pausing to enable intervening normal tissue to cool. | 02-05-2009 |
20090062697 | INSERTABLE ULTRASOUND PROBES, SYSTEMS, AND METHODS FOR THERMAL THERAPY - Disclosed herein are methods and systems for producing hemostasis, tissue closure, or vessel closure by inserting a thermal delivery probe into a passageway and emitting thermal energy from the probe to produce the hemostasis or tissue closure. These methods and systems may be used following a percutaneous medical procedure that creates a passageway in tissue of patient, such as is caused by introduction of an access device into the patient. The thermal delivery probe may have one or more ultrasound transducers positioned in an elongated shaft. | 03-05-2009 |
20100310138 | FINDING PAIRED ISOTOPE GROUPS - A technique for finding paired isotope groups of peptides, metabolic materials, or other materials is executed without having to identify features. Any suitable isotopic labeling methods, such as SILAC or ICAT, can be used. The technique can identify isotope pairs by pairing heavy and light labeled peptides based on mono-isotopes. The technique searches for isotope groups that have retention time and mass/charge within given tolerances, adjustable by users. Multiple label sites are supported as well as reverse-labeling to inhibit or reduce biases. Multiple replicates can be merged into a composite image. | 12-09-2010 |
20110021913 | USE OF FOCUSED ULTRASOUND FOR VASCULAR SEALING - An ultrasonic applicator unit ( | 01-27-2011 |
20110066085 | FORMATION OF ULTRASOUND BASED HEATING REGIONS ADJACENT BLOOD VESSELS - An ultrasound system used for both imaging and delivery high intensity ultrasound energy therapy to treatment sites and a method for treating tumors and other undesired tissue within a patient's body with an ultrasound device. The ultrasound device has an ultrasound transducer array disposed on a distal end of an elongate, relatively thin shaft. In one form of the invention, the transducer array is disposed within a liquid-filled elastomeric material that more effectively couples ultrasound energy into the tumor, that is directly contacted with the device. Using the device in a continuous wave mode, a necrotic zone of tissue having a desired size and shape (e.g., a necrotic volume selected to interrupt a blood supply to a tumor) can be created by controlling at least one of the f-number, duration, intensity, and direction of the ultrasound energy administered. This method speeds the therapy and avoids continuously pausing to enable intervening normal tissue to cool. | 03-17-2011 |
20110110569 | DISCOVER BIOLOGICAL FEATURES USING COMPOSITE IMAGES - An image processing system extracts parts or characteristics of interest from prepared biological samples One suitable use of the image processing system is to find biomarkers. But many other suitable uses are possible. Some components of the system include image preprocessing (data interpolation, retention time alignment, image noise filtering, background estimation, and formation of a composite image); image feature extraction (peaks, isotope groups, and charge groups); and computation of feature characteristics and expression statistics, differential expression, and non-differential expression. Outputs of the system include a candidate list of parts or characteristic of interest for aiding further discovery. | 05-12-2011 |
20110118602 | METHODS AND APPARATUS FOR FOCUSED ULTRASOUND APPLICATION - An ultrasonic applicator unit ( | 05-19-2011 |
20110178403 | METHODS AND DEVICES TO TARGET VASCULAR TARGETS WITH HIGH INTENSITY FOCUSED ULTRASOUND - An ultrasonic applicator unit ( | 07-21-2011 |
20110178445 | METHODS AND DEVICES TO TARGET VASCULAR TARGETS WITH HIGH INTENSITY FOCUSED ULTRASOUND - An ultrasonic applicator unit ( | 07-21-2011 |
20120059258 | USE OF FOCUSED ULTRASOUND FOR VASCULAR SEALING - An ultrasonic applicator unit ( | 03-08-2012 |
20120108966 | USE OF FOCUSED ULTRASOUND FOR VASCULAR SEALING - Methods for applying heat to a region proximate a blood vessel are disclosed. In one embodiment, a method can include generating an imaging ultrasound beam adapted to image a blood vessel target and receiving a reflection of the imaging ultrasound beam. The method can also include producing an output signal in response to the reflection of the imaging ultrasonic beam and processing the output signal to identify a location of a treatment zone proximate an outer wall of the blood vessel. Therapeutic energy can be applied to the treatment zone. In some embodiments, the therapeutic ultrasound energy beam can be moved to over-scan the treatment zone. Other methods are also disclosed. | 05-03-2012 |
20120108967 | USE OF FOCUSED ULTRASOUND FOR VASCULAR SEALING - Methods for applying heat to a region proximate a blood vessel are disclosed. In one embodiment, a method can include generating an imaging ultrasound beam adapted to image a blood vessel target and receiving a reflection of the imaging ultrasound beam. The method can also include producing an output signal in response to the reflection of the imaging ultrasonic beam and processing the output signal to identify a location of a treatment zone proximate an outer wall of the blood vessel. Therapeutic energy can be applied to the treatment zone. In some embodiments, the therapeutic ultrasound energy beam can be moved to over-scan the treatment zone. Other methods are also disclosed. | 05-03-2012 |
20140121568 | CONTROLLED HIGH EFFICIENCY LESION FORMATION USING HIGH INTENSITY ULTRASOUND - An ultrasound system used for both imaging and delivery high intensity ultrasound energy therapy to treatment sites and a method for treating tumors and other undesired tissue within a patient's body with an ultrasound device. The ultrasound device has an ultrasound transducer array disposed on a distal end of an elongate, relatively thin shaft. In one form of the invention, the transducer array is disposed within a liquid-filled elastomeric material that more effectively couples ultrasound energy into the tumor, that is directly contacted with the device. Using the device in a continuous wave mode, a necrotic zone of tissue having a desired size and shape (e.g., a necrotic volume selected to interrupt a blood supply to a tumor) can be created by controlling at least one of the f-number, duration, intensity, and direction of the ultrasound energy administered. This method speeds the therapy and avoids continuously pausing to enable intervening normal tissue to cool. | 05-01-2014 |
Lihui Weng, Ames, IA US
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20100029789 | Load Bearing Hydrogel Implants - The present invention features dual network hydrogels that possess the structural, mechanical, and biological properties required of load bearing three-dimensional support structures. | 02-04-2010 |
20100233267 | COMPOSITE HYDROGEL - The present invention features a composite hydrogel for use as soft tissue substitutes and transitional three-dimensional support structures. | 09-16-2010 |
Lihui Weng, Woodbury, MN US
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20110082427 | BIORESORBABLE EMBOLIZATION MICROSPHERES - The present disclosure is generally directed to an embolic material which, in some embodiments, may be in the form of a microsphere or a plurality of microspheres. The embolic material generally comprises carboxymethyl chitosan (CCN) crosslinked with carboxymethyl cellulose (CMC). In some embodiments, the embolic material may further comprise a therapeutic agent, such as doxorubicin. | 04-07-2011 |
20140099374 | BIORESORBABLE EMBOLIZATION MICROSPHERES - The present disclosure is generally directed to an embolic material which, in some embodiments, may be in the form of a microsphere or a plurality of microspheres. The embolic material generally comprises carboxymethyl chitosan (CCN) crosslinked with carboxymethyl cellulose (CMC). In some embodiments, the embolic material may further comprise a therapeutic agent, such as doxorubicin. | 04-10-2014 |
20140171907 | LIQUID EMBOLIC MATERIAL INCLUDING CARBOXYMETHYL CHITOSAN CROSSLINKED WITH CARBOXYMETHYL CELLULOSE - A liquid embolic material may include a mixture of a first solution comprising between about 1.2% and about 2.5% weight per volume (w/v) carboxymethyl chitosan (CCN) in a first solvent and a second solution comprising between about 1.2% and about 2.5% w/v oxidized carboxymethyl cellulose (OCMC) in a second solvent. The liquid embolic material may be used to embolize a targeted embolization location by mixing the first solution and the second solution to form a liquid embolic material (or hydrogel precursor material), introducing the hydrogel precursor material to a targeted embolization location within a body of a patient, and allowing the CCN and the OCMC to react to form the hydrogel material and embolize the targeted embolization location. | 06-19-2014 |
Lilian Weng, Bloomington, IN US
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20160042284 | SYSTEMS AND METHODS FOR PREDICTING MEME VIRALITY BASED ON NETWORK STRUCTURE - Systems and methods for predicting virality of a content item are disclosed. A method includes: receiving a social network structure; identifying communities within the social network structure, where communities are identified as dense subnetworks in the social network structure; receiving social network content that includes one or more content items; and identifying one or more content items that are predicted to become viral based on utilization of the content items between different communities in the social network structure. | 02-11-2016 |
Lingkai Weng, Malvern, PA US
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20090291956 | SALTS OF 2-FLUORO-N-METHYL-4-[7-(QUINOLIN-6-YL-METHYL)-IMIDAZO[1,2-b][1,2,- 4]TRIAZIN-2-YL]BENZAMIDE AND PROCESSES RELATED TO PREPARING THE SAME - The present invention is directed to dihydrochloric acid and dibenzenesulfonic acid salts of the c-Met kinase inhibitor 2-fluoro-N-methyl-4-[7-(quinolin-6-ylmethyl)-imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide, and pharmaceutical compositions thereof, useful in the treatment of cancer and other diseases related to the dysregulation of kinase pathways. The present invention further relates to processes and intermediates for preparing 2-fluoro-N-methyl-4-[7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide, and salts thereof. | 11-26-2009 |
20100015178 | 1,2,5-OXADIAZOLES AS INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE - The present invention is directed to 1,2,5-oxadiazole derivatives, and compositions of the same, which are inhibitors of indoleamine 2,3-dioxygenase and are useful in the treatment of cancer and other disorders, and to the processes and intermediates for making such 1,2,5-oxadiazole derivatives. | 01-21-2010 |
20120058079 | 1,2,5-Oxadiazoles as Inhibitors of Indoleamine 2,3-Dioxygenase - The present invention is directed to 1,2,5-oxadiazole derivatives, and compositions of the same, which are inhibitors of indoleamine 2,3-dioxygenase and are useful in the treatment of cancer and other disorders, and to the processes and intermediates for making such 1,2,5-oxadiazole derivatives. | 03-08-2012 |
20130289036 | SALTS OF 2-FLUORO-N-METHYL-4-[7-(QUINOLIN-6-YL-METHYL)-IMIDAZO[1,2-B][1,2,- 4]TRIAZIN-2-YL]BENZAMIDE AND PROCESSES RELATED TO PREPARING THE SAME - The present invention is directed to dihydrochloric acid and dibenzenesulfonic acid salts of the c-Met kinase inhibitor 2-fluoro-N-methyl-4-[7-(quinolin-6-ylmethyl)-imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide, and pharmaceutical compositions thereof, useful in the treatment of cancer and other diseases related to the dysregulation of kinase pathways. The present invention further relates to processes and intermediates for preparing 2-fluoro-N-methyl-4-[7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide, and salts thereof. | 10-31-2013 |
20140023663 | 1,2,5-Oxadiazoles As Inhibitors Of Indoleamine 2,3-Dioxygenase - The present invention is directed to 1,2,5-oxadiazole derivatives, and compositions of the same, which are inhibitors of indoleamine 2,3-dioxygenase and are useful in the treatment of cancer and other disorders, and to the processes and intermediates for making such 1,2,5-oxadiazole derivatives. | 01-23-2014 |
20140315962 | 1,2,5-Oxadiazoles As Inhibitors Of Indoleamine 2,3- Dioxygenase - The present invention is directed to 1,2,5-oxadiazole derivatives, and compositions of the same, which are inhibitors of indoleamine 2,3-dioxygenase and are useful in the treatment of cancer and other disorders, and to the processes and intermediates for making such 1,2,5-oxadiazole derivatives. | 10-23-2014 |
20150133674 | PROCESS FOR THE SYNTHESIS OF AN INDOLEAMINE 2,3-DIOXYGENASE INHIBITOR - The present application is directed to processes and intermediates for making 4-({2-[(aminosulfonyl)amino]ethyl}amino)-N-(3-bromo-4-fluorophenyl)-N′-hydroxy-1,2,5-oxadiazole-3-carboximidamide, which is an inhibitor of indoleamine 2,3-dioxygenase, useful in the treatment of cancer and other disorders. | 05-14-2015 |
20150148348 | SALTS OF 2-FLUORO-N-METHYL-4-[7-(QUINOLIN-6-YL-METHYL)- IMIDAZO[1,2-B][1,2,4]TRIAZIN-2-YL]BENZAMIDE AND PROCESSES RELATED TO PREPARING THE SAME - The present invention is directed to dihydrochloric acid and dibenzenesulfonic acid salts of the c-Met kinase inhibitor 2-fluoro-N-methyl-4-[7-(quinolin-6-ylmethyl)-imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide, and pharmaceutical compositions thereof, useful in the treatment of cancer and other diseases related to the dysregulation of kinase pathways. The present invention further relates to processes and intermediates for preparing 2-fluoro-N-methyl-4-[7-(quinolin-6-ylmethyl)imidazo[1,2-b][1,2,4]triazin-2-yl]benzamide, and salts thereof. | 05-28-2015 |
20150190378 | 1,2,5-Oxadiazoles As Inhibitors Of Indoleamine 2,3- Dioxygenase - The present invention is directed to 1,2,5-oxadiazole derivatives, and compositions of the same, which are inhibitors of indoleamine 2,3-dioxygenase and are useful in the treatment of cancer and other disorders, and to the processes and intermediates for making such 1,2,5-oxadiazole derivatives. | 07-09-2015 |
Min Weng, Novi, MI US
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20080309138 | AUTOMOTIVE SEAT RECLINING SYSTEM - A cross member assembly for adjusting a reclinable vehicle seat includes a joint. The joint permits the cross member assembly to deflect during a vehicle impact if the reclinable vehicle seat is occupied. | 12-18-2008 |
Qing Ping Weng, Wellesley, MA US
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20100009992 | AMPK MODULATORS - The present invention relates to compounds and pharmaceutically acceptable salts, esters and prodrugs of Formula (I) or (II): | 01-14-2010 |
20120302576 | AMPK MODULATORS - The present invention relates to compounds and pharmaceutically acceptable salts, esters and prodrugs of Formula (I) or (II): | 11-29-2012 |
20150266892 | AMPK Modulators - The present invention relates to compounds and pharmaceutically acceptable salts, esters and prodrugs of Formula (I) or (II): | 09-24-2015 |
Sheldon Weng, Lake Oswego, OR US
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20160006350 | TECHNIQUES FOR REDUCING SWITCHING NOISE AND IMPROVING TRANSIENT RESPONSE IN VOLTAGE REGULATORS - Methods and apparatus relating to reducing switching noise and improving transient response in voltage regulators are described. In an embodiment, one or more pulses are inserted into an output waveform of a voltage regulator. The one or more pulses introduce multiple frequencies into the output waveform of the voltage regulator (e.g., to reduce acoustic noise). In another embodiment, the output voltage of a voltage regulator is modified in response to comparison of the output voltage with at least one of a plurality of threshold values. The plurality of threshold values includes an upper trigger point voltage value and a lower trigger point voltage value. Other embodiments are also disclosed and claimed. | 01-07-2016 |
So-Yu Weng US
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20130119952 | Methods and Apparatus For Regulating Output Voltage of a Power Supply System - A power supply system includes a first connector, a second connector, a first circuit for detecting a magnitude of a current drawn from an energy source by the power supply system and providing a related output related, and a second circuit for adjusting an output voltage supplied to the second connector based on output of the first circuit. The output voltage supplied to the second connector is at a first value when the output of the first circuit is below a first threshold. Further, the output voltage supplied to the second connector is at a second value, greater than said first value, when the output of the first circuit is above a second threshold. The output voltage supplied to the second connector is at a third value, between said first and second values, when the output of the first circuit is between the first and second thresholds. | 05-16-2013 |
Tzu-Chen Weng, Troy, MI US
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20130181429 | Driver Airbag with Improved Head and Neck Injury Prevention - An airbag assembly includes a steering wheel, an airbag housing mounted to a hub of the steering wheel, and an airbag stored in the housing. The airbag includes a rim-facing panel, a driver-facing panel, an upper tether extending between the housing and a first location on the driver-facing panel opposite from the hub, and a lower tether extending between the housing and a second location below the first location. The tethers shape the airbag to have a thicker head contact portion adjacent to the upper rim of the steering wheel and a thinner chest contact portion adjacent to the lower rim of the steering wheel. The shape provides more balanced occupant protection in a frontal crash event, because the thicker head contact portion reduces the driver's head acceleration and neck injury. | 07-18-2013 |
20150151707 | HEAD, TORSO AND KNEE COMBO AIRBAG - A motor vehicle airbag system comprises a dual chambered combined head, torso, and knee airbag having a head and torso chamber and a lower extremities chamber in fluid communication with the head and torso chamber. A multidirectional inflator substantially simultaneously inflates both of the head and torso chamber and the lower extremities chamber. The head and torso chamber in the inflated condition acts against a head and a torso of the motor vehicle occupant to generate a restraining force against the occupant to mitigate contact of the occupant head and torso with the upper portion of the instrument panel during the impact event. The lower extremities chamber in the inflated condition acts against the pair of knees of the occupant to mitigate contact of the knees of the occupant with the lower portion of the panel during the impact event. | 06-04-2015 |
20150239373 | PYROTECHNIC FASTENER SEAT ARRANGEMENT FOR UNBELTED OCCUPANT PROTECTION - A seat assembly including a seat pan that drops vertically in the event of a frontal impact event to help safeguard against the head of an unbelted seat occupant striking the headliner, windshield or other components of the vehicle. The seat assembly includes a seat pan attached to a seat track. The seat track further includes an attachment bracket. A swing linkage movably connects the seat pan with the seat track by a movable fastener. A slot is formed in the bracket through which at least a part of the movable fastener passes. A pyrotechnic fastener also attaches the swing linkage to the bracket. In a frontal impact event the pyrotechnic fastener is caused to explode thus separating the pyrotechnic fastener into two parts and allowing the swing linkage and its attached seat pan to drop vertically relative to the seat track, thereby lowering the unbelted occupant. | 08-27-2015 |
Wei Weng, Naperville, IL US
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20150376463 | COPPER BARRIER CHEMICAL-MECHANICAL POLISHING COMPOSITION - A chemical-mechanical polishing composition includes colloidal silica abrasive particles having a chemical compound incorporated therein. The chemical compound may include a nitrogen-containing compound such as an aminosilane or a phosphorus-containing compound. Methods for employing such compositions include applying the composition to a semiconductor substrate to remove at least a portion of at least one of a copper, a copper barrier, and a dielectric layer. | 12-31-2015 |
Wei Weng, Argonne, IL US
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20120082903 | FUNCTIONALIZED IONIC LIQUID ELECTROLYTES FOR LITHIUM ION BATTERIES - An ionic liquid that is a salt has a Formula: | 04-05-2012 |
Wei Weng, Woodridge, IL US
Patent application number | Description | Published |
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20110294017 | REDOX SHUTTLES FOR LITHIUM ION BATTERIES - Compounds may have general Formula IVA or IVB. | 12-01-2011 |
20130171484 | Materials and Methods for Autonomous Battery Shutdown - An autonomous battery shutdown system includes a battery including an anode and a cathode, and an electrolyte composition between the anode and the cathode. The electrolyte composition includes an ionically conductive liquid containing lithium ions, and temperature-sensitive particles including a polymer having a melting temperature between 60° C. and 120° C. When the temperature of the battery exceeds 120° C., the temperature-sensitive particles form an ion barrier that traverses the battery. The resulting shutdown battery may have a specific charge capacity that is more than 98% lower than the specific charge capacity of the original battery. | 07-04-2013 |
20130189571 | ORGANIC ACTIVE MATERIALS FOR BATTERIES - A rechargeable battery includes a compound having at least two active sites, R | 07-25-2013 |
20130288137 | REDOX SHUTTLES HAVING AN AROMATIC RING FUSED TO A 1,1,4,4-TETRASUBSTITUTED CYCLOHEXANE RING - An electrolyte includes an alkali metal salt; an aprotic solvent; and a redox shuttle additive including an aromatic compound having at least one aromatic ring fused with at least one non-aromatic ring, the aromatic ring having two or more oxygen or phosphorus-containing substituents. | 10-31-2013 |
20130337347 | ULTRASOUND ASSISTED IN-SITU FORMATION OF CARBON/SULFUR CATHODES - A process of preparing an E-carbon nanocomposite includes contacting a porous carbon substrate with an E-containing material to form a mixture; and sonicating the mixture to form the E-carbon nanocomposite; where E is S, Se, Se | 12-19-2013 |
20140255794 | SULFUR CATHODE HOSTED IN POROUS ORGANIC POLYMERIC MATRICES - A composite material includes a porous organic polymer and an electrochemically active material, wherein the porous organic polymer contains a plurality of pores having a diameter of from about 0.1 nm to about 100 nm, and the electrochemically active material is disposed within the pores. | 09-11-2014 |
20150037691 | REDOX SHUTTLES FOR LITHIUM ION BATTERIES - An electrolyte may include compounds of general Formula IVA or IVB. | 02-05-2015 |
20150288031 | FUNCTIONALIZED IONIC LIQUID ELECTROLYTES FOR LITHIUM ION BATTERIES - An ionic liquid that is a salt has a Formula: | 10-08-2015 |
Weifeng Weng, Wynnewood, PA US
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20110119072 | METHOD AND SYSTEM FOR DETERMINING A FAIR BENCHMARK FOR PHYSICIANS' QUALITY OF PATIENT CARE - Described herein are systems, methods and computer-program products for application of both the Angoff standard-setting procedure with the Dunn-Rankin scaling method to determine standards (or cutscores) for practice-based performance assessments. In addition, reliability of measures and overall performance scores, and estimates of the decision consistency of the resulting performance standard can be calculated. | 05-19-2011 |
Wensheng Weng, Canton, MI US
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20100242626 | Self-compensating magnetoelastic torque sensor system - An improved magnetic torque transducer arrangement for self-compensating effects of external magnetic sources and temperature offset comprises a shaft with at least one magnetized zone, at least one active magnetic field sensor and at least one passive magnetic field sensor disposed in such a way that active field sensor always in a position with higher magnetic field strength arise from applied torque than that of passive sensor. Passive field sensors may also be placed in both sides of the active field sensor, or on one side of active field sensor only. The transducer output is obtained by subtract the output of passive field sensors from that of active field sensor thus cancel out the effect of interfering magnetic field flux and temperature offset on the torque transducer, and partially filter out temperature sensitivity drift and rotational dependant signal. The sensitivity of active and passive field sensors can also be electrically matched by calibrating them in a uniform magnetic field, thus a completely common mode rejection can be achieved. The sensor arrangements may also be utilized in other type of sensors that extract changes in magnetic fields to indirectly detect direction, speed, presence, force, linear position, or angle to cancel out interfering magnetic field and temperature offset effect. | 09-30-2010 |
20110162464 | Reduced Ambient Fields Error In A Magnetoelastic Torque Sensor System - An improved magnetic torque transducer involves a method and apparatus for compensating effects of uniform and/or non-uniform magnetic sources by placing three sets of magnetic field sensors around a shaft with at least one magnetized zone. The set of primary magnetic field sensor or sensors is placed proximate to the magnetized zone, both the second and third sets of secondary magnetic field sensors being placed by pre-determined distances to the primary set of magnetic field sensor or sensors, so that primary field sensors always in a position with higher magnetic field strength arise from applied torque than that of secondary sensors. And a method is developed to use the second and third signals from secondary sensors to adjust the primary signal to compensating for the effects of the uniform and/or non-uniform ambient magnetic field sources. | 07-07-2011 |
Xiaowei Weng, Fulshear, TX US
Patent application number | Description | Published |
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20150204174 | SYSTEM AND METHOD FOR PERFORMING STIMULATION OPERATIONS - A system and method is provided for performing a fracturing operation about a wellbore penetrating a subterranean formation. The method may acquire integrated wellsite data. The method may generate a mechanical earth model using the integrated wellsite data. The method may simulate an intersection of an induced hydraulic fracture with a natural fracture using the mechanical earth model. The method may determine intersection properties of the intersected natural fracture. The method may also generate a stimulation plan using the mechanical earth model and the intersection properties. The stimulation plan may include a fluid viscosity or a rate of injection of a fracturing fluid. | 07-23-2015 |
20160047207 | SYSTEM AND METHOD FOR PERFORMING DOWNHOLE STIMULATION OPERATIONS - A system and method for performing stimulation operations at a wellsite having a subterranean formation with of a reservoir therein is provided. The method involves generating a plurality of quality indicators from a plurality of logs, and combining the plurality of quality indicators to form a composite quality indicator. The plurality of stress blocks may then be merged using diversion criterion. The composite quality indicator may be combined with the merged stress blocks to form a combined stress and composite quality indicator, the combined stress and composite quality indicator comprising a plurality of blocks with boundaries therebetween. The method may further comprise defining stages along the combined stress and composite quality indicator based on the diverter-assisted stage classifications; and selectively positioning perforations in select stages based on the diverter-assisted stage classifications thereon. | 02-18-2016 |
20160108705 | METHOD OF CALIBRATING FRACTURE GEOMETRY TO MICROSEISMIC EVENTS - A method of performing a fracture operation is provided at a wellsite. The wellsite is positioned about a subterranean formation having a wellbore therethrough and a complex fracture network therein. The complex fracture network includes natural fractures, and the wellsite stimulated by injection of an injection fluid with proppant into the complex fracture network. The method involves generating wellsite data comprising measurements of microseismic events of the subterranean formation, modeling a hydraulic fracture network and a discrete fracture network of the complex fracture network based on the wellsite data, and performing a seismic moment operation. The method involves determining an actual seismic moment density based on the wellsite data and a predicted seismic moment density based on shear and tensile components of the simulated hydraulic fracture network, and calibrating the discrete fracture network based on a comparison of the predicted moment density and the actual moment density. | 04-21-2016 |
20160115771 | SYSTEM AND METHOD FOR PERFORMING DOWNHOLE STIMULATION OPERATIONS - A system and method for performing stimulation operations at a wellsite having a subterranean formation with of a reservoir therein is provided. The method involves performing reservoir characterization to generate a mechanical earth model based on integrated petrophysical, geomechanical and geophysical data. The method also involves generating a stimulation plan by performing well planning, a staging design, a stimulation design and a production prediction based on the mechanical earth model. The stimulation design is optimized by repeating the well planning, staging design, stimulation design, and production prediction in a feedback loop until an optimized stimulation plan is generated. | 04-28-2016 |
Xuejun Weng, Little Rock, AR US
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20090080721 | Method and system for image pumping - A method and system to “pump” radiation therapy (RT) images and associated patient information on an Image Guided Radiation Therapy (IGRT) system to a Record and Verify (R&V) system via a standard DICOM connection to allow remote image viewing. Targeted image files in IGRT systems are searched for and transferred automatically. The user identifies the “inlet,” i.e. the source from which the image files are searched, and the “outlet,” i.e., the DICOM server to which the “pumped” imaged are directed. The images can be sent in their original form or fused. The “input” source is scanned periodically at a user-determined time interval. In order not to send the same image multiple time, a time filter skips images generated before a user-selected time and date. | 03-26-2009 |
Yao-Chung Weng, Cambridge, MA US
Patent application number | Description | Published |
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20100288043 | Method and apparatus for extended time and varying environment measurements of single particles in microfluidic channels - Methods and apparatus for improving measurements of particle or cell characteristics, such as mass, in Suspended Microchannel Resonators (SMR's). Apparatus include in particular designs for trapping particles in SMR's for extended measurement periods and for changing the fluid properties within the SMR during the extended periods. Methods include techniques to provide for cell growth over time and over time in response to changing fluid properties to aid in determining parameters such as drug resistance and drug susceptibility. | 11-18-2010 |
20100297747 | SYSTEM AND METHOD FOR MONITORING CELL GROWTH - Microsystem for monitoring cell growth. A microfluidic structure is designed to allow cells to circulate therethrough and the microfluidic structure includes modules to monitor mass, mass density and fluorescence of the cell. | 11-25-2010 |
20120118063 | APPARATUS AND METHOD FOR MEASURING BUOYANT MASS AND DEFORMABILITY OF SINGLE CELLS - Method for determining buoyant mass and deformability of a cell. The method includes introducing the cell into a suspended microchannel resonator that includes a constriction near a distal location in the resonator. A first frequency shift in the resonator is monitored as a cell moves to the distal location in the resonator, the first frequency shift being related to the buoyant mass of the cell. Transit time of the cell through the constriction is measured by monitoring a second frequency shift as a result of a change in cell location as it passes through the constriction, whereby deformability is determined from the measured buoyant mass and transit time. | 05-17-2012 |
20140096604 | Method and Apparatus for Trapping Single Particles in Microfluidic Channels - Methods and apparatus for improving measurements of particle or cell characteristics, such as mass, in Suspended Microchannel Resonators (SMR's). Apparatus include in particular designs for trapping particles in SMR's for extended measurement periods. Methods include techniques to provide differential measurements by varying the fluid density for repeated measurements on the same particle or cell. | 04-10-2014 |
Yao-Chung Weng, Camonage, MA US
Patent application number | Description | Published |
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20100154535 | Method and apparatus for trapping single particles in microfluidic channels - Methods and apparatus for improving measurements of particle or cell characteristics, such as mass, in Susppended Microchannel Resonators (SMR's). Apparatus include in particular designs for trapping particles in SMR's for extended measurement periods. Methods include techniques to provide differential measurements by varying the fluid density for repeated measurements on the same particle or cell. | 06-24-2010 |
Yi Weng, Lafayette, LA US
Patent application number | Description | Published |
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20160109222 | HYBRID RAMAN AND BRILLOUIN SCATTERING IN FEW-MODE FIBERS - Methods and systems of sensing conditions in a fiber includes launching a light beam into a fiber. A first branch of scattered light is set to a mode other than a fundamental mode. A second branch of scattered light is optically filtered to remove unscattered input light. Brillouin scattered light is coherently detected on the first branch to produce a combined temperature/strain profile of the fiber. Raman scattered light on the second branch is directly detected to produce a temperature profile of the fiber. A strain profile of the fiber is determined, using a processor, based on the combined temperature/strain profile and the temperature profile. | 04-21-2016 |
20160109223 | DISTRIBUTED BRILLOUIN SENSING USING CORRELATION - Methods and systems for sensing conditions of a fiber include splitting a light signal into two branches. A first branch is converted to have a mode different from that of the second branch. Both branches are mode multiplexed into a single fiber. An output of the fiber is mode demultiplexed into the two branches. The first branch is mode converted to its original mode. Brillouin scattering patterns of the two branches are compared to determine a temperature and strain profile of the fiber. | 04-21-2016 |
20160109361 | LASER SPECTROSCOPIC SENSOR USING ORBITAL ANGULAR MOMENTUM - A method and system for optical angular momentum (OAM) spectroscopy includes generating a beam of light having a single OAM mode. A first spectrum of the beam of light is detected and the beam of light is passed through a gas to attenuate the beam of light in accordance with a presence and concentration of a respective gas. A second spectrum the beam of light is coherently detected and a difference between the first and second spectrum for the beam of light is analyzed to determine the presence and concentration of the respective gas. | 04-21-2016 |
Yi-Lan Weng, Baltimore, MD US
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20150366949 | COMPOSITIONS AND METHODS FOR INIHIBITING THE ACTIVITY OF LAR FAMILY PHOSPHATASES - A method of inhibiting and/or reducing the activity, signaling, and/or function of leukocyte-common antigen related (LAR) family of phosphatases in a cell of a subject induced by proteoglycans includes administering to the cell a therapeutic agent that inhibits one or more of catalytic activity, signaling, and function of the LAR family phosphatases without inhibiting binding to or activation the LAR family phosphatases by the proteoglycans. | 12-24-2015 |
Yiming Weng, Alpharetta, GA US
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20150118294 | Triggerable Compositions For Two-Stage, Controlled Release of Proactive Chemistry - A triggerable composition for two-stage, controlled release of a functional active chemical includes a trigonelline ester of a functional active with at least one hydroxyl group configured to release the functional active through a hydrolysis reaction upon contact with an aqueous medium, and an encapsulation material for encapsulating the trigonelline ester including a functional active, the encapsulation material triggerable to release the trigonelline ester upon the occurrence of an environmental stimulus. In other aspects, a viscous liquid or an absorbent article includes a triggerable composition for two-stage, controlled release of a functional active chemical, the composition including a trigonelline ester of a functional active with at least one hydroxyl group configured to release the functional active through a hydrolysis reaction upon contact with an aqueous medium, and an encapsulation material for encapsulating the trigonelline ester including a functional active. | 04-30-2015 |
20150238394 | Triggerable Compositions For Two-Stage, Controlled Release of Proactive Chemistry Using Aldehydes - A triggerable composition for two-stage, controlled release of a functional active chemical includes an aldehyde-based functional active incorporated in an organic salt-based acetal that releases the functional active through a hydrolysis reaction upon contact with an aqueous medium, and an encapsulation material for encapsulating the organic salt-based acetal, the encapsulation material triggerable to release or expose the organic salt-based acetal upon the occurrence of an environmental stimulus such as a pH change. The triggerable composition can be included in an absorbent article having at least one absorbent layer or in a viscous liquid such as a lotion, cream, or medicament. | 08-27-2015 |
Zhigang Weng, Brookline, MA US
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20100003258 | FIBROBLAST GROWTH FACTOR RECEPTOR 3 (FGFR3) BINDING PROTEINS - Monoclonal antibodies that bind and inhibit activation of fibroblast growth factor receptor 3 (FGFR3) are disclosed. The antibodies can be used to treat cell proliferative diseases and disorders, including certain forms of cancer, associated with activation of FGFR3. | 01-07-2010 |
20110305687 | ANTI-FGFR2 ANTIBODIES - Monoclonal antibodies that bind and inhibit biological activities of human FGFR2 are disclosed. The antibodies can be used to treat cell proliferative diseases and disorders, including certain forms of cancer, associated with activation or overexpression of FGFR2. | 12-15-2011 |
20130288305 | ANTI-FGFR2 ANTIBODIES - Monoclonal antibodies that bind and inhibit biological activities of human FGFR2 are disclosed. The antibodies can be used to treat cell proliferative diseases and disorders, including certain forms of cancer, associated with activation or overexpression of FGFR2. | 10-31-2013 |
20140193427 | ANTI-GDF15 ANTIBODIES - Monoclonal antibodies that bind and inhibit the activity of human GDF15 are disclosed. The antibodies can be used to treat body weight loss, including cachexia, associated with the over-expression of human GDF15. | 07-10-2014 |
20160083465 | ANTI-GDF15 ANTIBODIES - Monoclonal antibodies that bind and inhibit the activity of human GDF15 are disclosed. The antibodies can be used to treat body weight loss, including cachexia, associated with the over-expression of human GDF15. | 03-24-2016 |
Zhiping Weng, Wellesley, MA US
Patent application number | Description | Published |
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20120040869 | SEQUENCE PRESERVED DNA CONVERSION - Described herein are inexpensive high throughput methods to convert a target single stranded DNA (ssDNA) such that each nucleotide (or base) adenine (A), thymine (T), guanine (G) and cytosine (C) is converted to a pre-determined oligonucleotide code, with the sequential order preserved in the converted ssDNA, or RNA. The method does not require the use of DNA polymerases during the cycles and involves the use of an oligonucleotide probe library with repeated cycles of ligation and cleavage. At each cycle, one or more nucleotides on one end (e.g., either the 5′ end or the 3′ end) of a target, e.g., ssDNA, are cleaved and then ligated with the corresponding oligonucleotide code at the other end of the target ssDNA. | 02-16-2012 |
20130256118 | Use of Nanopore Arrays For Multiplex Sequencing of Nucleic Acids - Described are techniques for optical detection of single molecule signals from a nanopore array for analysis of nucleic acid sequences. These techniques are useful for rapid multiplexed DNA sequencing. | 10-03-2013 |
20140341809 | High-Affinity DMF5 T Cell Receptor (TCR) Variants - High-affinity variants of the DMF5 TCR, and methods of use thereof for the treatment and imaging of cancer in a patient. | 11-20-2014 |
Zude Weng, Wilmington, DE US
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20120110694 | PLANT MYB TRANSCRIPTION FACTOR HOMOLOGS - This invention relates to an isolated nucleic acid fragment encoding a Myb-related transcription factor. The invention also relates to the construction of a chimeric gene encoding all or a portion of the Myb-related transcription factor, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the Myb-related transcription factor in a transformed host cell. | 05-03-2012 |
Zude Weng, Vernon Hills, IL US
Patent application number | Description | Published |
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20080301842 | PLANT RNA TRANSPORT AND RNA-DIRECTED RNA POLYMERASE PROTEINS - This invention relates to an isolated nucleic acid fragment encoding a RNA-directed RNA polymerase. The invention also relates to the construction of a chimeric gene encoding all or a substantial portion of the RNA-directed RNA polymerase, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the RNA-directed RNA polymerase in a transformed host cell. | 12-04-2008 |
20090049574 | AUXIN TRANSPORT PROTEINS - This invention relates to an isolated nucleic acid fragment encoding an auxin transport protein. The invention also relates to the construction of a chimeric gene encoding all or a substantial portion of the auxin transport protein, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the auxin transport protein in a transformed host cell. The present invention also relates to methods using the auxin transport protein in modulating root development, and in discovering compounds with potential herbicidal activity. | 02-19-2009 |
20090282585 | PLANT MYB TRANSCRIPTION FACTOR HOMOLOGS - This invention relates to an isolated nucleic acid fragment encoding a Myb-related transcription factor. The invention also relates to the construction of a chimeric gene encoding all or a portion of the Myb-related transcription factor, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the Myb-related transcription factor in a transformed host cell. | 11-12-2009 |
20110030090 | Disease resistance genes - The invention provides isolated peptide-methionine sulfoxide reductase nucleic acids and their encoded proteins. The present invention provides methods and compositions relating to altering peptide-methionine sulfoxide reductase levels in plants. The invention further provides recombinant expression cassettes, host cells, transgenic plants, and antibody compositions. | 02-03-2011 |
Zude Weng, Rolling Meadows, IL US
Patent application number | Description | Published |
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20100077505 | Auxin Transport Proteins - This invention relates to an isolated nucleic acid fragment encoding an auxin transport protein. The invention also relates to the construction of a chimeric gene encoding all or a substantial portion of the auxin transport protein, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the auxin transport protein in a transformed host cell. The present invention also relates to methods using the auxin transport protein in modulating root development, and in discovering compounds with potential herbicidal activity. | 03-25-2010 |
20110003697 | PLANT MYB TRANSCRIPTION FACTOR HOMOLOGS - This invention relates to an isolated nucleic acid fragment encoding a Myb-related transcription factor. The invention also relates to the construction of a chimeric gene encoding all or a portion of the Myb-related transcription factor, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the Myb-related transcription factor in a transformed host cell. | 01-06-2011 |