Patent application number | Description | Published |
20120166325 | ENHANCED SYSTEM AND METHOD FOR MANAGING FINANCIAL MARKET INFORMATION - A system and method are provided for managing financial market information. According to certain embodiments, the system includes a computer having a memory, processor, and display. The processor is capable of generating a graphical depiction of the financial market information on the display. The graphical depiction includes a multidimensional representation of a broad range of market information for at least two financial instruments. The graphical depiction resides in a single window on the display. The financial instruments may include multiple different classes of financial instruments, such as treasuries and futures. Different instruments may be selected and information, including basis information, relevant to the selected instruments may be displayed in a second window. | 06-28-2012 |
20140207646 | ENHANCED SYSTEM AND METHOD FOR MANAGING FINANCIAL MARKET INFORMATION - A system and method are provided for managing financial market information. According to certain embodiments, the system includes a computer having a memory, processor, and display. The processor is capable of generating a graphical depiction of the financial market information on the display. The graphical depiction includes a multidimensional representation of a broad range of market information for at least two financial instruments. The graphical depiction resides in a single window on the display. The financial instruments may include multiple different classes of financial instruments, such as treasuries and futures. Different instruments may be selected and information, including basis information, relevant to the selected instruments may be displayed in a second window. | 07-24-2014 |
Patent application number | Description | Published |
20090171833 | SYSTEM AND METHOD FOR DISPLAYING AND/OR ANALYZING A LIMIT ORDER BOOK - According to one embodiment, a method of generating a display of a limit order book is provided. Data regarding a plurality of limit orders entered onto an electronic market is received and recorded, at least temporarily. The data regarding each limit order includes a price and a time associated with that limit order. Based on the received data, a graphical display is generated that indicates, for each recorded limit order entered into the electronic market within a period of time, the price and the time associated with that limit order. The price associated with each limit order is indicated by a first axis of the graphical display and the time associated with each limit order is indicated by a second axis of the graphical display. The graphical display may be displayed using an electronic display device. | 07-02-2009 |
20100299632 | SYSTEM AND METHOD FOR MANAGING FINANCIAL MARKET DATA WITH HIDDEN INFORMATION - Systems and methods that manage financial market data with hidden information. The systems and methods may receive market data about a plurality of financial instruments. The plurality of financial instruments comprises at least two different kinds of financial instruments. Hidden information is generated, based on the market data. The hidden information is viewable only after scrolling a cursor over a graphical element. The systems and methods also generate, based on the market data, a first graphical element that is embedded with hidden information. The first graphical element is displayed on a display. An indication is received indicating that the cursor has scrolled over the first graphical element. In response to the indication, the hidden information that is embedded in the first graphical element is displayed on the display. | 11-25-2010 |
20110145134 | SYSTEM AND METHOD FOR MANAGING TRANSACTIONS OF FINANCIAL INSTRUMENTS - A system and method for managing transactions of financial instruments that comprises generating a graphical representation having a plurality of multi-dimensional objects positioned along an axis. Each position along the axis represents a price of a financial instrument. The system receives an indication that at least one multi-dimensional object has been selected. The system generates, in response to the at least one multi-dimensional object being selected, a dialog box in the graphical representation. The system receives information relating to a transaction of the financial instrument. The information is displayed in the dialog box and comprises a desired volume of the financial instrument at a specific price. The system communicates to a remote device the information. The remote device is in communication with the processor over a network. The system receives an indication that the transaction of the financial instrument has been executed for the desired volume at the specific price. | 06-16-2011 |
20130097063 | SYSTEM AND METHOD FOR DISPLAYING AND/OR ANALYZING A LIMIT ORDER BOOK - Various systems and methods for determining information about limit orders is provided. Data regarding a plurality of limit orders entered onto an electronic market is received and stored. For each of a subset of the plurality of limit orders, a market distance is determined. The market distance comprises the difference between the price of the respective limit order and a market price. A weighting of the respective limit order is determined based at least on the determined market distance for the respective limit order. One or more market indicators is determined based at least in part on the weighting of each of the at least two limit orders. The one or more market indicators are caused to be displayed in a graphical user interface. | 04-18-2013 |
Patent application number | Description | Published |
20090264377 | Anti-neoplastic compositions comprising extracts of black cohosh - A method is provided for treating, preventing or ameliorating neoplasia in a subject. This method includes administering to the subject an amount of actein or an amount of an extract of black cohosh that contains a triterpene glycoside, which amount of the actein or black cohosh is effective to treat, prevent or ameliorate the neoplasia, in combination with an amount of a statin which is effective to treat, prevent, or ameliorate the neoplasia. Related methods for treating, preventing or ameliorating breast cancer, or liver cell neoplasia are also provided. In addition, methods for modulating a cholesterol biosynthesis pathway and a stress response pathway in a subject are provided. These methods include administering to a subject a composition comprising an anti-neoplastic synergistic amount of a statin and actein. Compositions for carrying out such methods are also provided. | 10-22-2009 |
20120208776 | ANTI-NEOPLASTIC COMPOSITIONS COMPRISING EXTRACTS OF BLACK COHOSH - A method is provided for treating, preventing or ameliorating neoplasia in a subject. This method includes administering to the subject an amount of actein or an amount of an extract of black cohosh that contains a triterpene glycoside, which amount of the actein or black cohosh is effective to treat, prevent or ameliorate the neoplasia, in combination with an amount of a statin which is effective to treat, prevent, or ameliorate the neoplasia. Related methods for treating, preventing or ameliorating breast cancer, or liver cell neoplasia are also provided. In addition, methods for modulating a cholesterol biosynthesis pathway and a stress response pathway in a subject are provided. These methods include administering to a subject a composition comprising an anti-neoplastic synergistic amount of a statin and actein. Compositions for carrying out such methods are also provided. | 08-16-2012 |
Patent application number | Description | Published |
20090093528 | METHODS FOR PROMOTING COMPOSITE TISSUE REGENERATION AND USES THEREOF - The present invention provides a use and method for GM284 to promote the regeneration of a bodily structure, comprised of a composite tissue in a subject. Additionally, the present invention provides a use and method for GM284 to promote composite tissue regeneration in a subject. The present invention further provides a use and method for GM284 to promote the regeneration of cells of a composite tissue in a subject. Finally, the present invention provides a use and method for GM284 to treat an injury to a composite tissue in a subject in need of such treatment. | 04-09-2009 |
20100317711 | STEM-LIKE CELLS AND METHOD FOR REPROGRAMMING ADULT MAMMALIAN SOMATIC CELLS - A new use is provided for small molecule inhibitors of Oct4 and Sox 2 as a cellular reprogramming agent and a method of reprogramming adult mammalian somatic cells into stem-like cells is provided, using small molecule inhibitors of Oct4 and Sox 2 without the need of any material derived from embryos or fetuses, and without the need of potentially harmful transfecting vectors. Stem-like cells created by the present invention can be induced to differentiate into terminally differentiated adult somatic cells, such as, for example, neuronal cells. | 12-16-2010 |
20100330063 | STEM-LIKE CELLS, METHOD FOR DE-DIFFERENTIATING MAMMALIAN SOMATIC CELLS INTO STEM-LIKE CELLS, AND METHOD FOR DIFFERENTIATING STEM-LIKE CELLS - A new use is provided for small molecule inhibitors of Oct4 and Sox 2 as a cellular reprogramming agent and a method of reprogramming adult mammalian somatic cells into stem-like cells is provided, using small molecule inhibitors of Oct4 and Sox 2 without the need of any material derived from embryos or fetuses, and without the need of potentially harmful transfecting vectors. Stem-like cells created by the present invention can be induced to differentiate into terminally differentiated adult somatic cells, such as, for example, neuronal cells. | 12-30-2010 |
Patent application number | Description | Published |
20140089043 | Audience Size Estimation and Complex Segment Logic - Selection of a trait may be received. A complex segment rule may be created that is usable to evaluate one or more qualification events. For example, the segment rule may be usable to evaluate a combined recency and frequency of the one or more qualification events. The qualification events may be based on collected network data associated with the plurality of visitors with each qualification event corresponding to a separate qualification of visitor according to the trait. The qualification events may be evaluated together according to the segment rule. For example, the combined recency and frequency of the one or more qualification events may be evaluated according to the segment rule. Evaluating the segment rule may include estimating a segment population size in real-time. | 03-27-2014 |
20140108139 | Marketing Segment Rule Definition for Real-time and Back-end Processing - A marketing segment rule for access by both a real-time component and a back end component may be stored. The real-time component may be configured to qualify a visitor to network content in a marketing segment during the visitor's visit to the network content. The back end component may be configured to qualify the visitor in the marketing segment after the visitor's visit to the network content. Qualification of a first visitor in a marketing segment may be determined. Such a determination may include evaluating network content data for the first visitor according to the marketing segment rule. An indication of the first visitor's segment qualification may be stored. An online advertisement may be presented to the first visitor based on the first visitor's segment qualification. | 04-17-2014 |
20140180804 | Tunable Algorithmic Segments - Tunable algorithmic segment techniques are described. In one or more implementations, a target audience definition is obtained that is input to initiate creation of a look-alike model. The target audience definition indicates traits associated with a baseline group of consumers who have interacted with online resources in a designated manner, such as by buying a product, visiting a website, using a service, and so forth. Tuning parameters designated for the look-alike model are ascertained and the look-alike model is built based on the target audience definition and the tuning parameters. The tuning parameters may include at least a setting selectable to control reach versus accuracy for the look-alike model. Segment data indicative of market segments generated according to the look-alike model may then be exposed for manipulation by a client. The manipulation may include selectable control over the tuning parameters to generate different look-alike groups from the segment data. | 06-26-2014 |
Patent application number | Description | Published |
20120278061 | GENERATING ACOUSTIC MODELS - This document describes methods, systems, techniques, and computer program products for generating and/or modifying acoustic models. Acoustic models and/or transformations for a target language/dialect can be generated and/or modified using acoustic models and/or transformations from a source language/dialect. | 11-01-2012 |
20130297310 | GENERATING ACOUSTIC MODELS - This document describes methods, systems, techniques, and computer program products for generating and/or modifying acoustic models. Acoustic models and/or transformations for a target language/dialect can be generated and/or modified using acoustic models and/or transformations from a source language/dialect. | 11-07-2013 |
20140114661 | METHODS AND SYSTEMS FOR SPEECH RECOGNITION PROCESSING USING SEARCH QUERY INFORMATION - Methods and systems for speech recognition processing are described. In an example, a computing device may be configured to receive information indicative of a frequency of submission of a search query to a search engine for a search query composed of a sequence of words. Based on the frequency of submission of the search query exceeding a threshold, the computing device may be configured to determine groupings of one or more words of the search query based on an order in which the one or more words occur in the sequence of words of the search query. Further, the computing device may be configured to provide information indicating the groupings to a speech recognition system. | 04-24-2014 |
20150039299 | CONTEXT-BASED SPEECH RECOGNITION - A processing system receives an audio signal encoding a portion of an utterance. The processing system receives context information associated with the utterance, wherein the context information is not derived from the audio signal or any other audio signal. The processing system provides, as input to a neural network, data corresponding to the audio signal and the context information, and generates a transcription for the utterance based on at least an output of the neural network. | 02-05-2015 |
20150154002 | USER INTERFACE CUSTOMIZATION BASED ON SPEAKER CHARACTERISTICS - Characteristics of a speaker are estimated using speech processing and machine learning. The characteristics of the speaker are used to automatically customize a user interface of a client device for the speaker. | 06-04-2015 |
20150371631 | CACHING SPEECH RECOGNITION SCORES - Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for caching speech recognition scores. In some implementations, one or more values comprising data about an utterance are received. An index value is determined for the one or more values. An acoustic model score for the one or more received values is selected, from a cache of acoustic model scores that were computed before receiving the one or more values, based on the index value. A transcription for the utterance is determined using the selected acoustic model score. | 12-24-2015 |
20160093294 | ACOUSTIC MODEL TRAINING CORPUS SELECTION - The present disclosure relates to training a speech recognition system. One example method includes receiving a collection of speech data items, wherein each speech data item corresponds to an utterance that was previously submitted for transcription by a production speech recognizer. The production speech recognizer uses initial production speech recognizer components in generating transcriptions of speech data items. A transcription for each speech data item is generated using an offline speech recognizer, and the offline speech recognizer components are configured to improve speech recognition accuracy in comparison with the initial production speech recognizer components. The updated production speech recognizer components are trained for the production speech recognizer using a selected subset of the transcriptions of the speech data items generated by the offline speech recognizer. An updated production speech recognizer component is provided to the production speech recognizer for use in transcribing subsequently received speech data items. | 03-31-2016 |
Patent application number | Description | Published |
20090217391 | T1R3 A NOVEL TASTE RECEPTOR - The present invention relates to the discovery, identification and characterization of a receptor protein, referred to herein as T1R3, which is expressed in taste receptor cells and associated with the perception of bitter and sweet taste. The invention encompasses T1R3 nucleotides, host cell expression systems, T1R3 proteins, fusion protein, transgenic animals that express a T1R3 transgene, and recombinant “knock-out” animals that do not express T1R3. The invention further relates to methods for identifying modulators of the T1R3-mediated taste response and the use of such modulators to either inhibit or promote the perception of bitterness or sweetness. The modulators of T1R3 activity may be used as flavor enhancers in food, beverages and pharmaceuticals. | 08-27-2009 |
20130122525 | smFRET WITH MEMBRANE PROTEINS - This disclosure is directed to methods of conducting dynamic single-molecule fluorescence studies such as sm-FRET on a membrane protein which permits observation and quantification of conformational dynamics of a membrane protein. Also disclosed herein are mutant membrane proteins in which one or more mutations have been introduced for affixing a fluorophore, as well as reagents and kits containing such mutant membrane proteins for conducting dynamic single-molecule fluorescence studies. The methods and compositions disclosed herein can be used in screening for compounds that enhance or reduce the activity of a membrane protein, useful for treating diseases associated with the malfunction of the membrane protein or alterations in membrane protein conformation. | 05-16-2013 |
Patent application number | Description | Published |
20090075919 | Anti-neoplastic compositions comprising extracts of black cohosh - The present invention provides a composition for use in treating or preventing neoplasia, comprising an effective actein. The present invention also provides a composition for use in treating or preventing neoplasia, comprising an effective anti-neoplastic amount of an ethyl acetate extract of black cohosh. The present invention further provides a combination of anti-neoplastic agents, comprising an effective anti-neoplastic amount of an ethyl acetate extract of black cohosh and an effective anti-neoplastic amount of at least one additional chemopreventive or chemotherapeutic agent. Methods for treating and preventing neoplasia are also provided. | 03-19-2009 |
20090186837 | Anti-neoplastic compositions comprising extracts of black cohosh - A method for treating, preventing or ameliorating breast cancer is provided by administering a synergistic amount of digitoxin and either actein or an extract of black cohosh comprising triterpene glycosides, and optionally another chemopreventive agent which may be paclitaxel. Methods for treating or preventing a neoplasia using a synergistic combination, and compositions of a synergistic combination of a cardiac glycoside and either actein or an extract of black cohosh comprising triterpene glycosides, and optionally another chemopreventive agent which may be a taxane are also provided. The compositions may also be used in a method for modulating Na | 07-23-2009 |
20090264377 | Anti-neoplastic compositions comprising extracts of black cohosh - A method is provided for treating, preventing or ameliorating neoplasia in a subject. This method includes administering to the subject an amount of actein or an amount of an extract of black cohosh that contains a triterpene glycoside, which amount of the actein or black cohosh is effective to treat, prevent or ameliorate the neoplasia, in combination with an amount of a statin which is effective to treat, prevent, or ameliorate the neoplasia. Related methods for treating, preventing or ameliorating breast cancer, or liver cell neoplasia are also provided. In addition, methods for modulating a cholesterol biosynthesis pathway and a stress response pathway in a subject are provided. These methods include administering to a subject a composition comprising an anti-neoplastic synergistic amount of a statin and actein. Compositions for carrying out such methods are also provided. | 10-22-2009 |
20120034217 | ANTI-NEOPLASTIC COMPOSITIONS COMPRISING EXTRACTS OF BLACK COHOSH - The present invention provides a composition for use in treating or preventing neoplasia, comprising an effective actein. The present invention also provides a composition for use in treating or preventing neoplasia, comprising an effective anti-neoplastic amount of an ethyl acetate extract of black cohosh. The present invention further provides a combination of anti-neoplastic agents, comprising an effective anti-neoplastic amount of an ethyl acetate extract of black cohosh and an effective anti-neoplastic amount of at least one additional chemopreventive or chemotherapeutic agent. Methods for treating and preventing neoplasia are also provided. | 02-09-2012 |
20120208776 | ANTI-NEOPLASTIC COMPOSITIONS COMPRISING EXTRACTS OF BLACK COHOSH - A method is provided for treating, preventing or ameliorating neoplasia in a subject. This method includes administering to the subject an amount of actein or an amount of an extract of black cohosh that contains a triterpene glycoside, which amount of the actein or black cohosh is effective to treat, prevent or ameliorate the neoplasia, in combination with an amount of a statin which is effective to treat, prevent, or ameliorate the neoplasia. Related methods for treating, preventing or ameliorating breast cancer, or liver cell neoplasia are also provided. In addition, methods for modulating a cholesterol biosynthesis pathway and a stress response pathway in a subject are provided. These methods include administering to a subject a composition comprising an anti-neoplastic synergistic amount of a statin and actein. Compositions for carrying out such methods are also provided. | 08-16-2012 |
20120219643 | ANTI-NEOPLASTIC COMPOSITIONS COMPRISING EXTRACTS OF BLACK COHOSH - A method for treating, preventing or ameliorating breast cancer is provided by administering a synergistic amount of digitoxin and either actein or an extract of black cohosh comprising triterpene glycosides, and optionally another chemopreventive agent which may be paclitaxel. Methods for treating or preventing a neoplasia using a synergistic combination, and compositions of a synergistic combination of a cardiac glycoside and either actein or an extract of black cohosh comprising triterpene glycosides, and optionally another chemopreventive agent which may be a taxane are also provided. The compositions may also be used in a method for modulating Na | 08-30-2012 |
Patent application number | Description | Published |
20090186837 | Anti-neoplastic compositions comprising extracts of black cohosh - A method for treating, preventing or ameliorating breast cancer is provided by administering a synergistic amount of digitoxin and either actein or an extract of black cohosh comprising triterpene glycosides, and optionally another chemopreventive agent which may be paclitaxel. Methods for treating or preventing a neoplasia using a synergistic combination, and compositions of a synergistic combination of a cardiac glycoside and either actein or an extract of black cohosh comprising triterpene glycosides, and optionally another chemopreventive agent which may be a taxane are also provided. The compositions may also be used in a method for modulating Na | 07-23-2009 |
20090264377 | Anti-neoplastic compositions comprising extracts of black cohosh - A method is provided for treating, preventing or ameliorating neoplasia in a subject. This method includes administering to the subject an amount of actein or an amount of an extract of black cohosh that contains a triterpene glycoside, which amount of the actein or black cohosh is effective to treat, prevent or ameliorate the neoplasia, in combination with an amount of a statin which is effective to treat, prevent, or ameliorate the neoplasia. Related methods for treating, preventing or ameliorating breast cancer, or liver cell neoplasia are also provided. In addition, methods for modulating a cholesterol biosynthesis pathway and a stress response pathway in a subject are provided. These methods include administering to a subject a composition comprising an anti-neoplastic synergistic amount of a statin and actein. Compositions for carrying out such methods are also provided. | 10-22-2009 |
20120208776 | ANTI-NEOPLASTIC COMPOSITIONS COMPRISING EXTRACTS OF BLACK COHOSH - A method is provided for treating, preventing or ameliorating neoplasia in a subject. This method includes administering to the subject an amount of actein or an amount of an extract of black cohosh that contains a triterpene glycoside, which amount of the actein or black cohosh is effective to treat, prevent or ameliorate the neoplasia, in combination with an amount of a statin which is effective to treat, prevent, or ameliorate the neoplasia. Related methods for treating, preventing or ameliorating breast cancer, or liver cell neoplasia are also provided. In addition, methods for modulating a cholesterol biosynthesis pathway and a stress response pathway in a subject are provided. These methods include administering to a subject a composition comprising an anti-neoplastic synergistic amount of a statin and actein. Compositions for carrying out such methods are also provided. | 08-16-2012 |
20120219643 | ANTI-NEOPLASTIC COMPOSITIONS COMPRISING EXTRACTS OF BLACK COHOSH - A method for treating, preventing or ameliorating breast cancer is provided by administering a synergistic amount of digitoxin and either actein or an extract of black cohosh comprising triterpene glycosides, and optionally another chemopreventive agent which may be paclitaxel. Methods for treating or preventing a neoplasia using a synergistic combination, and compositions of a synergistic combination of a cardiac glycoside and either actein or an extract of black cohosh comprising triterpene glycosides, and optionally another chemopreventive agent which may be a taxane are also provided. The compositions may also be used in a method for modulating Na | 08-30-2012 |
Patent application number | Description | Published |
20110207483 | REASSIGNED MOBILE MESSAGE NOTIFICATIONS - The instant application describes a method of managing a customer's mobile station and providing a notification of a resultant change. The method includes steps of communicating over the air through a mobile communication network with a subscriber device management application running on the customer's mobile station; causing the subscriber device management application to attempt to change an operational control parameter of the customer's mobile station, via the over the air communication; and determining an outcome of the attempted change of the operational control parameter of the customer's mobile station. The method also includes a step of sending a mobile messaging service message, providing notification of the attempted change of the operational control parameter of the customer's mobile station, through the mobile communication network to another mobile station associated with the customer. | 08-25-2011 |
20120238239 | ACCOUNT HOLDER NOTIFICATION FOR AN INFRACTING MOBILE STATION OR MOBILE DIRECTORY NUMBER (MDN) - A mobile communication network offers notification to an account holder upon occurrence of an infraction of a subscriber selected restriction by operation of one of the mobile stations under the subscriber's account. In the examples, the subscriber can select a directory number/station under the account, a desired one of a number of available restriction options and one or more parameters of the selected restriction. When the mobile communication network detects an infraction, caused by operation of the mobile station through the network, a system or processor obtains a destination address designated for an account holder, for the subscriber's account, such as the directory number for one of the subscriber's stations selected as that of the account holder. The system sends a notification of the infraction intended for the account holder, using the destination address, for example, as a text message sent through the network to the account holder's mobile station. | 09-20-2012 |
20140057622 | REASSIGNED MOBILE MESSAGE NOTIFICATIONS - The instant application describes a method of managing a customer's mobile station and providing a notification of a resultant change. The method includes steps of communicating over the air through a mobile communication network with a subscriber device management application running on the customer's mobile station; causing the subscriber device management application to attempt to change an operation control parameter of the customer's mobile station via the over the air communication; and determining an outcome of the attempted change of the operational control parameter of the customer's mobile station. The method also includes a step of sending a mobile messaging service message, providing notification of the attempted change of the operational control parameter of the customer's mobile station, through the mobile communication network to another mobile station associated with the customer. | 02-27-2014 |
Patent application number | Description | Published |
20090264377 | Anti-neoplastic compositions comprising extracts of black cohosh - A method is provided for treating, preventing or ameliorating neoplasia in a subject. This method includes administering to the subject an amount of actein or an amount of an extract of black cohosh that contains a triterpene glycoside, which amount of the actein or black cohosh is effective to treat, prevent or ameliorate the neoplasia, in combination with an amount of a statin which is effective to treat, prevent, or ameliorate the neoplasia. Related methods for treating, preventing or ameliorating breast cancer, or liver cell neoplasia are also provided. In addition, methods for modulating a cholesterol biosynthesis pathway and a stress response pathway in a subject are provided. These methods include administering to a subject a composition comprising an anti-neoplastic synergistic amount of a statin and actein. Compositions for carrying out such methods are also provided. | 10-22-2009 |
20120208776 | ANTI-NEOPLASTIC COMPOSITIONS COMPRISING EXTRACTS OF BLACK COHOSH - A method is provided for treating, preventing or ameliorating neoplasia in a subject. This method includes administering to the subject an amount of actein or an amount of an extract of black cohosh that contains a triterpene glycoside, which amount of the actein or black cohosh is effective to treat, prevent or ameliorate the neoplasia, in combination with an amount of a statin which is effective to treat, prevent, or ameliorate the neoplasia. Related methods for treating, preventing or ameliorating breast cancer, or liver cell neoplasia are also provided. In addition, methods for modulating a cholesterol biosynthesis pathway and a stress response pathway in a subject are provided. These methods include administering to a subject a composition comprising an anti-neoplastic synergistic amount of a statin and actein. Compositions for carrying out such methods are also provided. | 08-16-2012 |
20120219643 | ANTI-NEOPLASTIC COMPOSITIONS COMPRISING EXTRACTS OF BLACK COHOSH - A method for treating, preventing or ameliorating breast cancer is provided by administering a synergistic amount of digitoxin and either actein or an extract of black cohosh comprising triterpene glycosides, and optionally another chemopreventive agent which may be paclitaxel. Methods for treating or preventing a neoplasia using a synergistic combination, and compositions of a synergistic combination of a cardiac glycoside and either actein or an extract of black cohosh comprising triterpene glycosides, and optionally another chemopreventive agent which may be a taxane are also provided. The compositions may also be used in a method for modulating Na | 08-30-2012 |