Patent application number | Description | Published |
20090062380 | ISOFLAVONES FOR TREATING MUCOPOLYSACCHARIDOSES - The invention relates to the medical use of natural isoflavones and their semisynthetic derivatives or the pharmaceutically acceptable salts thereof for the therapeutic and/or prophylactic treatment of diseases, at the base of which lies an excessive production or storage of glycosaminoglycans, especially for treatment of mucopolysaccharidoses. The isoflavones and their semisynthetic derivatives are represented by formula (I), in which R | 03-05-2009 |
20120190642 | ISOFLAVONES FOR TREATING MUCOPOLYSACCHARIDOSES - A method of treatment of mucopolysaccharidosis, the method including administering to a patient in the need of such treatment—a therapeutically effective amount of a natural isoflavone of formula (I), a derivative thereof, or a pharmaceutically acceptable salt thereof. A pharmaceutical composition including a pharmaceutically acceptable excipient; and a natural isoflavone of formula (I), a derivative thereof, or a pharmaceutically acceptable salt thereof, the natural isoflavone, the derivative thereof, or the pharmaceutically acceptable salt thereof being in a therapeutically effective amount for the treatment of mucopolysaccharidosis. | 07-26-2012 |
20140107051 | ISOFLAVONES FOR TREATING MUCOPOLYSACCHARIDOSES - A pharmaceutical composition including a pharmaceutically acceptable excipient; and a natural isoflavone of formula (I), a derivative thereof, or a pharmaceutically acceptable salt thereof, the natural isoflavone, the derivative thereof, or the pharmaceutically acceptable salt thereof being in a therapeutically effective amount for the treatment of mucopolysaccharidosis. A method of treatment of mucopolysaccharidosis, the method including administering to a patient in the need of such treatment—a therapeutically effective amount of a natural isoflavone of formula (I), a derivative thereof, or a pharmaceutically acceptable salt thereof. | 04-17-2014 |
Patent application number | Description | Published |
20090062380 | ISOFLAVONES FOR TREATING MUCOPOLYSACCHARIDOSES - The invention relates to the medical use of natural isoflavones and their semisynthetic derivatives or the pharmaceutically acceptable salts thereof for the therapeutic and/or prophylactic treatment of diseases, at the base of which lies an excessive production or storage of glycosaminoglycans, especially for treatment of mucopolysaccharidoses. The isoflavones and their semisynthetic derivatives are represented by formula (I), in which R | 03-05-2009 |
20120190642 | ISOFLAVONES FOR TREATING MUCOPOLYSACCHARIDOSES - A method of treatment of mucopolysaccharidosis, the method including administering to a patient in the need of such treatment—a therapeutically effective amount of a natural isoflavone of formula (I), a derivative thereof, or a pharmaceutically acceptable salt thereof. A pharmaceutical composition including a pharmaceutically acceptable excipient; and a natural isoflavone of formula (I), a derivative thereof, or a pharmaceutically acceptable salt thereof, the natural isoflavone, the derivative thereof, or the pharmaceutically acceptable salt thereof being in a therapeutically effective amount for the treatment of mucopolysaccharidosis. | 07-26-2012 |
20140107051 | ISOFLAVONES FOR TREATING MUCOPOLYSACCHARIDOSES - A pharmaceutical composition including a pharmaceutically acceptable excipient; and a natural isoflavone of formula (I), a derivative thereof, or a pharmaceutically acceptable salt thereof, the natural isoflavone, the derivative thereof, or the pharmaceutically acceptable salt thereof being in a therapeutically effective amount for the treatment of mucopolysaccharidosis. A method of treatment of mucopolysaccharidosis, the method including administering to a patient in the need of such treatment—a therapeutically effective amount of a natural isoflavone of formula (I), a derivative thereof, or a pharmaceutically acceptable salt thereof. | 04-17-2014 |
20150044671 | PROBES TARGETING THE GENE ENCODING THE SHIGA TOXIN AND USE THEREOF FOR DETECTION OF ENTEROHEMORRHAGIC ESCHERICHIA COLI (EHEC) - The invention relates to a method for detection of enterohemorrhagic | 02-12-2015 |
20150148551 | GENISTEIN FOR REDUCING LEVELS OF STORAGE COMPOUNDS IN THE TREATMENT AND/OR PREVENTION OF LYSOSOMAL STORAGE DISEASES (LSDS) - The subject of the invention is genistein for use in non-enzymatic method of treatment and/or prevention of the lysosomal storage diseases (LSDs) i.e. diseases with the underlying defect in degradation and resulting accumulation of organic compounds in lysosomes, to reduce the level of storage of organic compounds by reducing the rate of efficiency of accumulating organic substances synthesis and/or by increasing the rate of efficiency of cellular deposits degradation. | 05-28-2015 |
Patent application number | Description | Published |
20100158161 | POST DECODING SOFT INTERFERENCE CANCELLATION - The present patent application discloses a method and apparatus for decoding, comprising decoding signals iteratively, mutually exchanging extrinsic information, calculating APP LLRs for both systematic and parity bits and making a hard decision after a plurality of iterations is completed based on accumulated soft information. The present patent application also discloses a method and apparatus for post decoding soft interference canceling, comprising generating updated a posteriori probabilities for systematic and parity bits from a turbo decoder, mapping the posteriori probabilities to soft symbols, quantizing the soft symbols, re-encoding a data packet, filtering a chip sequence, reconstructing an interference waveform, and scaling reconstruction filter coefficients using the symbols. | 06-24-2010 |
20150100529 | COMPILING NETWORK DESCRIPTIONS TO MULTIPLE PLATFORMS - A method of generating executable code for a target platform in a neural network includes receiving a spiking neural network description. The method also includes receiving platform-specific instructions for one or more target platforms. Further, the method includes, generating executable code for the target platform(s) based on the platform-specific instructions and the network description. | 04-09-2015 |
20150106317 | SHARED MEMORY ARCHITECTURE FOR A NEURAL SIMULATOR - Aspects of the present disclosure provide methods and apparatus for allocating memory in an artificial nervous system simulator implemented in hardware. According to certain aspects, memory resource requirements for one or more components of an artificial nervous system being simulated may be determined and portions of a shared memory pool (which may include on-chip and/or off-chip RAM) may be allocated to the components based on the determination. | 04-16-2015 |
20150242744 | STOCHASTIC DELAY PLASTICITY - A method of operating a spiking neural network having neurons coupled together with a synapse includes monitoring a timing of a presynaptic spike and monitoring a timing of a postsynaptic spike. The method also includes determining a time difference between the postsynaptic spike and the presynaptic spike. The method further includes calculating a stochastic update of a delay for the synapse based on the time difference between the postsynaptic spike and the presynaptic spike. | 08-27-2015 |
Patent application number | Description | Published |
20090238754 | USE OF PYRENE TO CARRY PEPTIDES ACROSS THE BLOOD BRAIN BARRIER - Described are methods for delivering a peptide agent across the blood-brain barrier, comprising administering to a subject a conjugate comprising (i) a peptide agent and pyrene, and related detection and therapeutic methods. | 09-24-2009 |
20090274621 | USE OF PYRENE TO CARRY NON-PEPTIDE AGENTS ACROSS THE BLOOD BRAIN BARRIER - Described are methods for delivering a non-peptide agent across the blood-brain barrier, comprising administering to a subject a conjugate comprising (i) a non-peptide agent and (ii) pyrene, and related detection and therapeutic method. | 11-05-2009 |
20100233095 | CONFORMATIONALLY DYNAMIC PEPTIDES - Disclosed are novel peptides that are useful, for example, for detecting target proteins having a β-sheet secondary structure which may be associated with a disease, and for diagnosing and treating such a disease. Related methods and kits also are disclosed. | 09-16-2010 |
20130108549 | PEPTIDE PROBES FOR DIAGNOSTICS AND THERAPEUTICS | 05-02-2013 |
20150133632 | CONFORMATIONALLY DYNAMIC PEPTIDES - Disclosed are novel peptides that are useful, for example, for detecting target proteins having a β-sheet secondary structure which may be associated with a disease, and for diagnosing and treating such a disease. Related methods and kits also are disclosed. | 05-14-2015 |