Wanker
Erich Wanker, Berlin DE
Patent application number | Description | Published |
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20090117040 | Novel pharmaceutical and diagnostic compositions for use in the treatment and diagnosis of neurodegenerative diseases or amyloid diseases - The present invention relates to pharmaceutical and diagnostic compositions as well as to the use of the active substances contained therein for preparing a pharmaceutical or a diagnostic composition for the treatment or diagnosis of neurodegenerative disorders or amyloid diseases. | 05-07-2009 |
20120282629 | Enhancers of Protein Degradation - The present invention relates to compounds suitable for modulating huntingtin protein processing and useful for treating or preventing huntingtin-related disorders. The invention provides pharmaceutical compositions comprising said compounds and methods of syntheses thereof. | 11-08-2012 |
20130078186 | AZO COMPOUNDS REDUCING FORMATION AND TOXICITY OF AMYLOID BETA AGGREGATION INTERMEDIATES - The present invention relates to compounds suitable as modulators of protein misfolding and/or protein aggregation. The compounds are particularly suitable as inhibitors of amyloid aggregate formation and/or modulators of amyloid surface properties, and/or as activators of degradation or reduction of amyloid aggregates. | 03-28-2013 |
Erich E. Wanker, Berlin DE
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20100298280 | Compounds for the Modulation of Huntingtin Aggregation, Methods and Means for Identifying Such Compounds - The present invention relates to tetranortriterpenoid compounds and pharmaceutical compositions thereof, which are provided for use in the treatment, diagnosis and/or prevention of trinucleotide repeat disorders (like a polyglutamine diseases, e.g Huntingdon's disease), amyloid diseases, neurodegenerative disease, protein misfolding diseases or tumors. The tetranortriterpenoid compounds of the present invention are further provided for the reduction and/or inhibition of the aggregation of amyloidogenic proteins, preferably of polyglutamine proteins (such as huntingtin) as well as for increasing proteasome activity. The present invention furthermore relates to nucleic acids, comprising the nucleotide sequences of two huntingtin fragments, as well as to cells and kits, which are useful in methods for assessing the aggregation of huntingtin and in methods for identifying compounds, which modulate the aggregation of huntingtin. | 11-25-2010 |
Roland Wanker, Hart Bei Graz AT
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20110191079 | Method for Testing a Vehicle or a Sub-System Thereof - A method for testing a vehicle or a sub-system thereof on a test stand or in a road trial is described, wherein the method provides force and torque transmitting interfaces which are at least partially present in reality. | 08-04-2011 |
Roland Wanker, Hart Bei Graz AU
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20120225488 | PARTICULATE MEASUREMENT SYSTEM - Disclosed is a vehicle emissions monitoring system capable of providing an accurate, real-time estimate of an amount of particulate matter (PM) within a vehicle's exhaust. The system is capable of accurately differentiating the composition of that PM by identifying amounts attributable to soot, SOF, and sulfate. | 09-06-2012 |
William Paul Wanker, Santa Fe, NM US
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20090138329 | APPLICATION OF QUERY WEIGHTS INPUT TO AN ELECTRONIC COMMERCE INFORMATION SYSTEM TO TARGET ADVERTISING - An online commerce information system (OCIS) receives from a consumer a query in relation to a potential consumer transaction and also receives a set of weighting factors that correspond to the query, where the weighting factors pertain to stored data relevant to the potential consumer transaction. The OCIS causes a result of applying the query and the weighting factors to the stored data to be communicated to the consumer, in response to the query. The OCIS also selects an advertisement to be communicated to the consumer based on at least one of the weighting factors, and causes the selected advertisement to be communicated to the consumer. | 05-28-2009 |
20090138458 | APPLICATION OF WEIGHTS TO ONLINE SEARCH REQUEST - A machine-implemented search method comprises inputting a search query from a user, and before the query is executed, inputting from the user a weighting factor that has a specified relationship to the query. The method further includes initiating a search by causing the query to be applied according to the weighting factor, and returning a result of the search to the user. The weighting factor may represent, for example, a weight to be given to one of multiple information sources that are available to be searched in response to the query, such as an online search engine or a merchant online commerce web site. Alternatively, the weighting factor may represent a weight to be given to a term in the query. | 05-28-2009 |
20120233087 | CUSTOMIZABLE ELECTRONIC COMMERCE COMPARISON SYSTEM AND METHOD - In a consumer information system, a method of comparing products and services including providing product specific information, providing merchant specific information on the specified product, providing merchant specific business information, providing product specific information collected by third parties, providing merchant specific information collected by third parties, applying weighting factors to the information provided, producing an aggregate value for each merchant based on the weighting factors as applied to the information provided, and producing a ranking of the merchants offering the specified product based on the aggregate value for each merchant. The system provides for consumers to select a set of standardized weighting factors or to modify the standardized weighting factors or to create their own weighting factors. The system provides detailed information to consumers on the breakdown of factors influencing the rating. | 09-13-2012 |