Patent application number | Description | Published |
20120301896 | TSH ANTIBODIES FOR POINT-OF-CARE IMMUNOASSAY FORMATS - The invention relates to antibody characteristics used to design a whole blood Point of Care Thyroid Stimulating Hormone (TSH) immunoassay using an ELISA sandwich assay lacking one or more wash steps between the antigen capture, detection antibody addition and substrate introduction steps. This invention exhibits low cross reactivity with biologically similar interfering cross reacting species, such as Follicle Stimulating Hormone (FSH), Luteinizing Hormone (LH) and Chorionic Gonadotropin (CG). | 11-29-2012 |
20120301905 | TSH IMMUNOASSAYS AND PROCESSES FOR PERFORMING TSH IMMUNOASSAYS IN THE PRESENCE OF ENDOGENOUS CONTAMINANTS IN RESTRICTED WASH FORMATS - The invention relates to low wash Thyroid Stimulating Hormone (TSH) immunoassays using an ELISA sandwich assay having limited or no wash step between the antigen capture, detection antibody addition and substrate introduction steps. This invention exhibits low cross reactivity with biologically similar interfering cross reacting species, such as Follicle Stimulating Hormone (FSH), Luteinizing Hormone (LH) and Chorionic Gonadotropin (CG). | 11-29-2012 |
20140262776 | BIOSENSOR WITH IMPROVED INTERFERENCE CHARACTERISTICS - This invention relates to mutagenized redox oxidase enzymes used to design enzyme electrodes with improved interference characteristics in the presence of mediator and oxygen in the assay. This recombinant modified enzyme has enhanced capability to transfer electrons to redox mediator instead of its natural electron acceptors such as O | 09-18-2014 |
20140295476 | GLUTAMATE OXIDASE MUTAGENESIS FOR DIAGNOSTIC TESTING - The described invention provides a method of generating a catalytically active oxidase enzyme preparation. The described invention also provides a means of generating reagents for a protease detection sensor which can use colorimetric, fluorescent, or electrochemical detection. Further, the invention describes a system for a protease detecting sensor. | 10-02-2014 |
20160091512 | ELLAGIC ACID FORMULATIONS FOR USE IN COAGULATION ASSAYS - The present invention relates to ellagic acid formulations for performing coagulation assays that are highly stable for long term storage and reduce assay time. Particularly, aspects of the present invention are directed to a composition and method of preparing ellagic acid in a highly soluble format for use in a coagulation assay. For example, the ellagic acid may be solubilized in one or more of sodium hydroxide, methanol, a polyether compound, particularly polyethylene glycol, polyethylene oxide, or polyoxyethylene, and a cyclodextrin guest-host complex. | 03-31-2016 |
20160102337 | GLUTAMATE OXIDASE MUTAGENESIS FOR DIAGNOSTIC TESTING - The described invention provides a method for detecting a target analyte that exhibits protease enzyme activity. The described method includes contacting a sample with a hybrid oxidase enzyme engineered to exhibit increased catalytic activity over that of a starting oxidase enzyme upon cleavage of a mutated protease cleavage recognition sequence. The mutated protease cleavage recognition sequence is a recognition sequence specific for the target analyte. The described method further includes contacting a substrate with the engineered hybrid oxidase enzyme. The substrate comprises a cognate composition of matter to the engineered hybrid oxidase enzyme, and the engineered hybrid oxidase enzyme is configured to catalyze conversion of the cognate composition of matter into a detectable product upon proteolytic cleavage of the mutated protease cleavage recognition sequence by the target analyte. | 04-14-2016 |
Patent application number | Description | Published |
20100128730 | SIP-Enabled Framework for Multi-Domain Roaming Control Plane in a WiMAX Access Network - Middleware is provided as a control plane for WiMAX control messaging. Each ASN in a WiMAX system is associated with a Session Initiation Protocol (SIP) server. A plurality of Functional Entities (FEs) are distributed across the ASNs, wherein each FE (or a group of FEs) associated with a SIP agent. Each FE is operable to control a function associated with a subscriber station (SS). The function controlled by a first FE is transferred to a second FE by employing the SIP agents to establish a SIP session between the first and second FEs. WiMAX control messages are then exchanged over the established session to transfer the SS function from the first FE to the second FE. The first and second FEs may be in the same ASN—i.e. the SS mobility is intra-domain—or, the first and second FEs may be in different ASNs—i.e. the SS mobility is inter-domain. | 05-27-2010 |
20110182231 | METHODS AND SYSTEMS FOR A WIRELESS ROUTING ARCHITECTURE AND PROTOCOL - The present invention provides a method for generating routing paths in a multi-hop network. The multi-hop network includes a base station, at least one relay station, and at least one non-relay mobile station. The routing paths are paths between the base station and the at least one non-relay mobile station via the at least one relay station. The base station broadcasts a path discovery message (PDM) including a path list with a starting point of the path list being the base station. Each of the relay stations receives the PDM and updates the PDM by adding their own respective node identifier to the path list and broadcasting the updated PDM. The PDMs eventually reach the non-relay mobile station. The non-relay mobile stations reply to the base station by sending the base station the updated path list between the base station and the non-relay mobile station. In some embodiments the base station or the at least one non-relay mobile station acting as a source node sends a dynamic service (DSx) message including an end-to-end path list to an end of path destination. The relay stations use the path list to forward the message between the source node and the end of path destination. In some implementations the multi-hop network operates in a manner that is consistent with any one of: IEEE 802.16, IEEE 802.16d, and IEEE 802.16e. | 07-28-2011 |
20110243061 | METHOD AND SYSTEM FOR A WIRELESS MULTI-HOP RELAY NETWORK - In a wireless multi-hop relay network arranged in a tree topology, the base station and one or more relay stations are associated as a virtual base station (VBS). The base station and each relay station have a unique virtual base station identifier (VBS-ID) associated with the path defined by the base station and the one or more relay stations. a relay station in the branch uses its VBS-ID for communicating with an attached subscriber station (e.g. a mobile station) such that communications between the base station and subscriber station occur via the VBS. Subscriber station data communications are relayed between the base station and the one or more relay stations over the VBS via a tunnel connection. The VBS is autoconfigurable. Mobility for subscriber stations and relay stations is provided through reconfiguration of VBS's. | 10-06-2011 |
20110243062 | METHOD AND SYSTEM FOR A WIRELESS MULTI-HOP RELAY NETWORK - In a wireless multi-hop relay network arranged in a tree topology, the base station and one or more relay stations are associated as a virtual base station (VBS). The base station and each relay station have a unique virtual base station identifier (VBS-ID) associated with the path defined by the base station and the one or more relay stations. a relay station in the branch uses its VBS-ID for communicating with an attached subscriber station (e.g. a mobile station) such that communications between the base station and subscriber station occur via the VBS. Subscriber station data communications are relayed between the base station and the one or more relay stations over the VBS via a tunnel connection. The VBS is autoconfigurable. Mobility for subscriber stations and relay stations is provided through reconfiguration of VBS's. | 10-06-2011 |
20130094473 | SIP - ENABLED FRAMEWORK FOR MULTI-DOMAIN ROAMING CONTROL PLANE IN A WIMAX ACCESS NETWORK - Middleware is provided as a control plane for WiMAX control messaging. Each ASN in a WiMAX system is associated with a Session Initiation Protocol (SIP) server. A plurality of Functional Entities (FEs) are distributed across the ASNs, wherein each FE (or a group of FEs) associated with a SIP agent. Each FE is operable to control a function associated with a subscriber station (SS). The function controlled by a first FE is transferred to a second FE by employing the SIP agents to establish a SIP session between the first and second FEs. WiMAX control messages are then exchanged over the established session to transfer the SS function from the first FE to the second FE. The first and second FEs may be in the same ASN, or the first and second FEs may be in different ASNs. | 04-18-2013 |
20130142109 | METHOD AND SYSTEM FOR A WIRELESS MULTI-HOP RELAY NETWORK - In a wireless multi-hop relay network arranged in a tree topology, the base station and one or more relay stations are associated as a virtual base station (VBS). The base station and each relay station have a unique virtual base station identifier (VBS-ID) associated with the path defined by the base station and the one or more relay stations. a relay station in the branch uses its VBS-ID for communicating with an attached subscriber station (e.g. a mobile station) such that communications between the base station and subscriber station occur via the VBS. Subscriber station data communications are relayed between the base station and the one or more relay stations over the VBS via a tunnel connection. The VBS is autoconfigurable. Mobility for subscriber stations and relay stations is provided through reconfiguration of VBS's. | 06-06-2013 |
20150237564 | Method and System for a Wireless Multi-Hop Relay Network - In a wireless multi-hop relay network arranged in a tree topology, the base station and one or more relay stations are associated as a virtual base station (VBS). The base station and each relay station have a unique virtual base station identifier (VBS-ID) associated with the path defined by the base station and the one or more relay stations. A relay station in the branch uses its VBS-ID for communicating with an attached subscriber station (e.g. a mobile station) such that communications between the base station and subscriber station occur via the VBS. Subscriber station data communications are relayed between the base station and the one or more relay stations over the VBS via a tunnel connection. The VBS is autoconfigurable. Mobility for subscriber stations and relay stations is provided through reconfiguration of VBS's. | 08-20-2015 |
20150365876 | Methods and Systems for a Wireless Routing Architecture and Protocol - The present invention provides a method for generating routing paths in a multi-hop network. The multi-hop network includes a base station, at least one relay station, and at least one non-relay mobile station. The routing paths are paths between the base station and the at least one non-relay mobile station via the at least one relay station. The base station broadcasts a path discovery message (PDM) including a path list with a starting point of the path list being the base station. Each of the relay stations receives the PDM and updates the PDM by adding their own respective node identifier to the path list and broadcasting the updated PDM. The PDMs eventually reach the non-relay mobile station. The non-relay mobile stations reply to the base station by sending the base station the updated path list between the base station and the non-relay mobile station. In some embodiments the base station or the at least one non-relay mobile station acting as a source node sends a dynamic service (DSx) message including an end-to-end path list to an end of path destination. The relay stations use the path list to forward the message between the source node and the end of path destination. In some implementations the multi-hop network operates in a manner that is consistent with any one of: IEEE 802.16, IEEE 802.16d, and IEEE 802.16e. | 12-17-2015 |
20160099768 | Method and System for a Wireless Multi-Hop Relay Network - In a wireless multi-hop relay network arranged in a tree topology, the base station and one or more relay stations are associated as a virtual base station (VBS). The base station and each relay station have a unique virtual base station identifier (VBS-ID) associated with the path defined by the base station and the one or more relay stations. A relay station in the branch uses its VBS-ID for communicating with an attached subscriber station (e.g. a mobile station) such that communications between the base station and subscriber station occur via the VBS. Subscriber station data communications are relayed between the base station and the one or more relay stations over the VBS via a tunnel connection. The VBS is auto configurable. Mobility for subscriber stations and 10 relay stations is provided through reconfiguration of VBS's. | 04-07-2016 |
Patent application number | Description | Published |
20080209372 | Estimation Of Process Variation Impact Of Slack In Multi-Corner Path-Based Static Timing Analysis - A method and system for reducing a number of paths to be analyzed in a multi-corner static timing analysis. An estimated upper slack variation based on a non-common path delay for a racing path is utilized in determining if a multi-corner static timing analysis may be bypassed for a racing path. In another example, an estimated maximum RSS credit based on a total delay for a racing path is utilized in determining if a multi-corner static timing analysis may be bypassed for a racing path. | 08-28-2008 |
20080209373 | METHOD AND SYSTEM FOR EVALUATING STATISTICAL SENSITIVITY CREDIT IN PATH-BASED HYBRID MULTI-CORNER STATIC TIMING ANALYSIS - Methods, systems and computer program products for analyzing a timing design of an integrated circuit are disclosed. According to an embodiment, a method for analyzing a timing design of an integrated circuit comprises: providing an initial static timing analysis of the integrated circuit; selecting a static timing test with respect to a static timing test point based on the initial static timing analysis; selecting a timing path leading to the static timing test point for the static timing test; determining an integrated slack path variability for the timing path based on a joint probability distribution of at least one statistically independent parameter; and analyzing the timing design based on the integrated slack path variability. | 08-28-2008 |
20080209374 | Parameter Ordering For Multi-Corner Static Timing Analysis - A method and system for decreasing processing time in multi-corner static timing analysis. In one embodiment, parameters are ordered in a parameter order by decreasing magnitude of impact on variability of timing. In one example, a decreasing parameter order is utilized to order slack cutoff values that are assigned across a parameter process space. In another example, a decreasing parameter order is utilized to perform a multi-corner timing analysis on one or more dependent parameters in an independent fashion. | 08-28-2008 |
20080209375 | Variable Threshold System and Method For Multi-Corner Static Timing Analysis - A method and system for decreasing processing time in multi-corner static timing analysis. In one embodiment, slack cutoff values are assigned across a parameter process space. For example, a slack cutoff value is assigned to each parameter in a process space by determining an estimated maximum slack change between a starting corner and any other corner in a corresponding process sub-space. In another embodiment, parameters are ordered in a parameter order by decreasing magnitude of impact on variability of timing. | 08-28-2008 |
20110055793 | TIMING CLOSURE ON MULTIPLE SELECTIVE CORNERS IN A SINGLE STATISTICAL TIMING RUN - An approach for covering multiple selective timing corners in a single statistical timing run is described. In one embodiment, a single statistical timing analysis is run on the full parameter space that covers unlimited process parameters/environment conditions. Results from the statistical timing analysis are projected for selected corners. Timing closure is performed on the corners having the worst slacks. | 03-03-2011 |
20130018617 | INTEGRATING MANUFACTURING FEEDBACK INTO INTEGRATED CIRCUIT STRUCTURE DESIGNAANM Buck; Nathan C.AACI UnderhillAAST VTAACO USAAGP Buck; Nathan C. Underhill VT USAANM Dreibelbis; Brian M.AACI UnderhillAAST VTAACO USAAGP Dreibelbis; Brian M. Underhill VT USAANM Dubuque; John P.AACI JerichoAAST VTAACO USAAGP Dubuque; John P. Jericho VT USAANM Foreman; Eric A.AACI FairfaxAAST VTAACO USAAGP Foreman; Eric A. Fairfax VT USAANM Habitz; Peter A.AACI HinesburgAAST VTAACO USAAGP Habitz; Peter A. Hinesburg VT USAANM Hemmett; Jeffrey G.AACI St. GeorgeAAST VTAACO USAAGP Hemmett; Jeffrey G. St. George VT USAANM Venkateswaran; NatesanAACI Hopewell JunctionAAST NYAACO USAAGP Venkateswaran; Natesan Hopewell Junction NY USAANM Visweswariah; ChandramouliAACI Croton-on-HudsonAAST NYAACO USAAGP Visweswariah; Chandramouli Croton-on-Hudson NY USAANM Wang; XiaoyueAACI KanataAACO CAAAGP Wang; Xiaoyue Kanata CAAANM Zolotov; VladmimirAACI Putnam ValleyAAST NYAACO USAAGP Zolotov; Vladmimir Putnam Valley NY US - Solutions for integrating manufacturing feedback into an integrated circuit design are disclosed. In one embodiment, a computer-implemented method is disclosed including: defining an acceptable yield requirement for a first integrated circuit product; obtaining manufacturing data about the first integrated circuit product; performing a regression analysis on data representing paths in the first integrated circuit product to define a plurality of parameter settings based upon the acceptable yield requirement and the manufacturing data; determining a projection corner associated with the parameter settings for satisfying the acceptable yield requirement; and modifying a design of a second integrated circuit product based upon the projection corner and the plurality of parameter settings. | 01-17-2013 |
20130036395 | EFFICIENT SLACK PROJECTION FOR TRUNCATED DISTRIBUTIONS - Aspects of the present invention provide solutions for projecting slack in an integrated circuit. A statistical static timing analysis (SSTA) is computed to get a set of Gaussian distributions over a plurality of variation sources in the integrated circuit. Based on the Gaussian distributions, a truncated subset and a remainder subset of the Gaussian distributions are identified. Then data factors that represent a ratio between the remainder subset and the truncated subset are obtained. These data factors are applied to the SSTA to root sum square (RSS) project the slack for the integrated circuit that takes into account the absence of the truncated subset. | 02-07-2013 |
20130104092 | METHOD, SYSTEM AND PROGRAM STORAGE DEVICE FOR PERFORMING A PARAMETERIZED STATISTICAL STATIC TIMING ANALYSIS (SSTA) OF AN INTEGRATED CIRCUIT TAKING INTO ACCOUNT SETUP AND HOLD MARGIN INTERDEPENDENCE - In embodiments of a statistical static timing analysis (SSTA) method, system and program storage device, the interdependence between the setup time and hold time margins of a circuit block (e.g., a latch, flip-flop, etc., which requires the checking of setup and hold timing constraints) is determined, taking into account possible variations in multiple parameters (e.g., using a variation-aware characterizing technique). A parameterized statistical static timing analysis (SSTA) of a circuit incorporating the circuit block is performed in order to determine, in statistical parameterized form, setup and hold times for the circuit block. Based on the interdependence between the setup and hold time margins, setup and hold time constraints can be determined in statistical parameterized form. Finally, the setup and hold times determined during the SSTA can be checked against the setup and hold time constraints to determine, if the time constraints are violated or not and to what degree. | 04-25-2013 |