Patent application number | Description | Published |
20100056796 | Compounds Suitable As Precursors to Compounds that are Useful for Imaging Amyloid Deposits - The present invention relates to novel derivatives that are suitable as precursors to compounds that are useful for imaging amyloid deposits in living patients, their compositions, methods of use and processes to make such compounds. The compounds deriving from these precursors are useful in methods of imaging amyloid deposits in brain in vivo to allow antemortem diagnosis of Alzheimer's disease by positron emission tomography (PET) as well as measuring clinical efficacy of Alzheimer's disease therapeutic agents. Furthermore, the present invention also discloses the precursor compounds in crystalline form. | 03-04-2010 |
20100286392 | PROCESS FOR THE MANUFACTURING OF THE COMPOUND 2-HYDROXY-3-[5-(MORPHOLIN-4-YLMETHYL)PYRIDIN-2-YL]1H-INDOLE-5-CARBONITRIL- E 701 - The present invention relates to a new process for the manufacture of the compound 2-hydroxy-3-[5-(morpholin-4-ylmethyl)pyridin-2-yl]1H-indole-5-carbonitrile as a free base and pharmaceutically acceptable salts thereof, particularly the 2-hydroxy-3-[5-(morpholin-4-ylmethyl)pyridin-2-yl]1H-indole-5-carbonitrile citrate, and to new intermediates prepared in said process suitable for large scale manufacturing of said compound. | 11-11-2010 |
20120264943 | Compounds Suitable As Precursors to Compounds that are Useful for Imaging Amyloid Deposits - The present invention relates to novel derivatives that are suitable as precursors to compounds that are useful for imaging amyloid deposits in living patients, their compositions, methods of use and processes to make such compounds. The compounds deriving from these precursors are useful in methods of imaging amyloid deposits in brain in vivo to allow antemortem diagnosis of Alzheimer's disease by positron emission tomography (PET) as well as measuring clinical efficacy of Alzheimer's disease therapeutic agents. Furthermore, the present invention also discloses the precursor compounds in crystalline form. | 10-18-2012 |
20140296534 | COMPOUNDS SUITABLE AS PRECURSORS TO COMPOUNDS THAT ARE USEFUL FOR IMAGING AMYLOID DEPOSITS - The present invention relates to novel derivatives that are suitable as precursors to compounds that are useful for imaging amyloid deposits in living patients, their compositions, methods of use and processes to make such compounds. The compounds deriving from these precursors are useful in methods of imaging amyloid deposits in brain in vivo to allow antemortem diagnosis of Alzheimer's disease by positron emission tomography (PET) as well as measuring clinical efficacy of Alzheimer's disease therapeutic agents. Furthermore, the present invention also discloses the precursor compounds in crystalline form. | 10-02-2014 |
Patent application number | Description | Published |
20100260588 | Collapsible Storage and Transportation System - A flexible fluid storage system for holding large volumes of fluid and a process and apparatus for the handling and transportation of the flexible storage system is provided. The flexible storage system includes a main storage bag with an attachment apron with fingers, a ground sheet, a lay flat tube for fluid circulation, a pressure release port, and fill/drain ports. The flexible storage system is configured for attachment to a trailer and reel system such that the flexible storage system can be mechanically rolled onto or off of a reel on a semi-truck trailer bed for easy transportation, deployment, and storage of the flexible storage system. | 10-14-2010 |
20120063703 | Collapsible Storage and Transportation System - A flexible fluid storage system for holding large volumes of fluid and a process and apparatus for the handling and transportation of the flexible storage system is provided. The flexible storage system includes a main storage bag with an attachment apron with fingers, a ground sheet, a lay flat tube for fluid circulation, a pressure release port, and fill/drain ports. The flexible storage system is configured for attachment to a trailer and reel system such that the flexible storage system can be mechanically rolled onto or off of a reel on a semi-truck trailer bed for easy transportation, deployment, and storage of the flexible storage system. | 03-15-2012 |
20140023298 | SYSTEMS AND METHODS FOR THE STORAGE AND DISPOSAL OF WASTE CEMENT - A collapsible bladder system for the storage and disposal or re-use of cement returns from oil and gas wells is described. The collapsible bladder system includes a flexible storage bag having an input valve, an output valve and a vent that can be easily set up and transported by a single person. Cement returns are pumped into the flexible storage bag and allowed to harden into a cement block. The cement block covered with the storage bag can be hauled away for disposal or re-used for a secondary purpose, such as a barricade. | 01-23-2014 |
Patent application number | Description | Published |
20120187000 | ELECTROCHEMICAL SENSORS - Systems and methods are provided for detecting the presence of an analyte in a sample. A solid state electrochemical sensor can include a redox active moiety having an oxidation and/or reduction potential that is sensitive to the presence of an analyte immobilized over a surface of a working electrode. A redox active moiety having an oxidation and/or reduction potential that is insensitive to the presence of the analyte can be used for reference. Voltammetric measurements made using such systems can accurately determine the presence and/or concentration of the analyte in the sample. The solid state electrochemical sensor can be robust and not require calibration or re-calibration. | 07-26-2012 |
20130248364 | ELECTROCHEMICAL SENSORS - Systems and methods are provided for detecting the presence of an analyte in a sample. A solid state electrochemical sensor can include a redox active moiety having an oxidation and/or reduction potential that is sensitive to the presence of an analyte immobilized over a surface of a working electrode. A redox active moiety having an oxidation and/or reduction potential that is insensitive to the presence of the analyte can be used for reference. Voltammetric measurements made using such systems can accurately determine the presence and/or concentration of the analyte in the sample. The solid state electrochemical sensor can be robust and not require calibration or re-calibration. | 09-26-2013 |
20140042026 | ELECTROCHEMICAL SENSORS - Systems and methods are provided for detecting the presence of an analyte in a sample. A solid state electrochemical sensor can include a redox active moiety having an oxidation and/or reduction potential that is sensitive to the presence of an analyte immobilized over a surface of a working electrode. A redox active moiety having an oxidation and/or reduction potential that is insensitive to the presence of the analyte can be used for reference. Voltammetric measurements made using such systems can accurately determine the presence and/or concentration of the analyte in the sample. The solid state electrochemical sensor can be robust and not require calibration or re-calibration. | 02-13-2014 |
20140080733 | Use of marker panels for stratifying drug treatment options - Personalized medicine involves the use of a patient's molecular markers to guide treatment regimens for the patient. The scientific literature provides multiple examples of correlations between drug treatment efficacy and the presence or absence of molecular markers in a patient sample. Methods are provided herein that permit efficient dissemination of scientific findings regarding treatment efficacy and molecular markers found in patient tumors to health care providers. | 03-20-2014 |
20140141426 | Sequencing formalin fixed paraffin embedded samples - Personalized medicine involves the use of a patient's molecular markers to guide treatment regimens for the patient. The scientific literature provides multiple examples of correlations between drug treatment efficacy and the presence or absence of molecular markers in a patient sample. Methods are provided herein that permit efficient dissemination of scientific findings regarding treatment efficacy and molecular markers found in patient tumors to health care providers. | 05-22-2014 |
20140141980 | Stratifying and annotating a clinical practice guideline - Personalized medicine involves the use of a patient's molecular markers to guide treatment regimens for the patient. The scientific literature provides multiple examples of correlations between drug treatment efficacy and the presence or absence of molecular markers in a patient sample. Methods are provided herein that permit efficient dissemination of scientific findings regarding treatment efficacy and molecular markers found in patient tumors to health care providers. | 05-22-2014 |
Patent application number | Description | Published |
20140039750 | Method And System For Implementing Ultrasonic Sensor signal strength calibrations - Temperature compensation for ultrasonic sensors can have a significant error that is highly undesirable because temperature of ultrasonic sensors and the temperature of the medium through which they sense objects affect signal strength calibrations (e.g., echo thresholds) applied when detecting an object. In order to increase the detection capabilities and reported distance of an object, ultrasonic sensors need to adjust their detection criteria and distance calculations as the temperature of air surrounding a vehicle (i.e., outside air temperature) changes and also as the temperature of the sensor changes. Embodiments of the inventive subject matter provide for a simple, effective and consistent approach for determining a temperature upon which such detection criteria and distance calculation adjustments can be based. | 02-06-2014 |
20140300504 | ACTIVE PARK ASSIST OBJECT DETECTION - A method of assessing an area for parking a vehicle includes ultrasonically scanning the area to obtain ultrasonic data, radar scanning the area to obtain radar data, and determining whether to park the vehicle in the area based on both the ultrasonic data and the radar data. | 10-09-2014 |
20140313059 | PARK ASSIST OBJECT DISTANCE MEASUREMENT CLOCK CONTROL - A method of determining an object distance from a vehicle includes sending a first transmission signal during a first burst period from a first transmitter, listening for a first reflection signal during a first listen period in a receiver, and sending a second transmission signal during a second burst period from a second transmitter. The second transmission signal is sent based on a time when the first transmission signal is sent. | 10-23-2014 |
20140316632 | ENHANCED PARK ASSIST WHEEL SPEED COMPENSATION TECHNIQUE - A method of parking a vehicle includes calibrating a wheel speed count of the vehicle based on a measured length that is external to the vehicle, and parking the vehicle based on the calibrated wheel speed count. | 10-23-2014 |
20140347195 | ENHANCED ALIGNMENT METHOD FOR PARK ASSIST - A method of parking a running vehicle includes measuring a length of a parked vehicle that is proximate to a desired parking location, and estimating the width of the parked vehicle based on a regression equation. The running vehicle is parked based on the estimated width. | 11-27-2014 |