Patent application number | Description | Published |
20080260769 | Polypeptides for Oligomeric Assembly of Antigens - A system for expressing antigenic polypeptides in oligomeric form fuses the antigenic polypeptide to an oligomerisation polypeptide such that the oligomerisation polypeptide can interact with other oligomerisation polypeptides and bring multiple copies of the antigenic polypeptide into close proximity in the form of an oligomer. Expressing the polypeptides in oligomeric form in this way can improve their immunogenicity compared to a monomeric form. | 10-23-2008 |
20080267966 | Polypeptides from Non-Typeable Haemophilus Influenzae - Polypeptides comprising non-typeable | 10-30-2008 |
20090104218 | Group B Streptococcus - Polypeptides and nucleic acids from | 04-23-2009 |
20090176699 | Inhibitors Based on Fusion, Hr1 and Hr2 Sequences in Bacterial Adhesin - A known surface adhesin (NadA) in | 07-09-2009 |
20090232820 | NEISSERIA MENINGITIDIS ANTIGENS AND COMPOSITIONS - The invention provides proteins from | 09-17-2009 |
20090285845 | Domains And Epitopes Of Meningococcal Protein NMB1870 - ‘NMB1870’ is a known surface protein in | 11-19-2009 |
20090297542 | Adp-ribosylating toxin from listeria monocytogenes - An ADP-ribosylating toxin from | 12-03-2009 |
20090298099 | Gonococcal Proteins and Nucleic Acids - The invention provides proteins from gonococcus ( | 12-03-2009 |
20090317420 | Immunogenic compositions for gram positive bacteria such as streptococcus agalactiae - The invention relates to the identification of a new adhesin islands within the genomes of several Group A and Group B | 12-24-2009 |
20100034822 | Haemophilus Influenzae Type B - Polypeptides comprising various amino acid sequences derived from | 02-11-2010 |
20100047267 | Staphylococcus aureus proteins and nucleic acids - The invention provides proteins from | 02-25-2010 |
20100055130 | STAPHYLOCOCCUS AUREUS PROTEINS AND NUCLEIC ACIDS - The invention provides proteins from | 03-04-2010 |
20100105865 | Nucleic acids and proteins from streptococcus groups a & b - The invention provides proteins from group B | 04-29-2010 |
20100183653 | Fusion Proteins Comprising CD4 Minimal Modules and Methods of Use Thereof - Fusion proteins comprising CD4 minimal modules that bind to HIV Env polypeptides in a non-CD4 backbone are described. Also described are complexes of these fusion proteins with Env as well as methods of diagnosis, treatment and prevention using the polynucleotides and polypeptides are also provided. | 07-22-2010 |
20100267931 | HETEROLOGOUS EXPRESSION OF NEISSERIAL PROTEINS - Alternative and improved approaches to the heterologous expression of the proteins of | 10-21-2010 |
20100272725 | Neisserial antigens - The invention provides proteins from | 10-28-2010 |
20100303822 | Polypeptides from non-typeable haemophilus influenzae - Polypeptides comprising non-typeable | 12-02-2010 |
20100303864 | CONSERVED AND SPECIFIC STREPTOCOCCAL GENOMES - The invention relates to polynucleotides which are conserved or specific to one or more species of | 12-02-2010 |
20110020385 | COMBINATIONS OF PNEUMOCOCCAL RrgB CLADES - Pneumococcal pilus subunit RrgB has at least three clades. Serum raised against a given clade is active against pneumococci which express that RrgB clade, but is not active against strains which express one of the other two clades i.e. there is intra-clade cross-protection, but not inter-clade cross-protection. Thus an immunogenic composition can include at least two different clades of RrgB to improve strain coverage against pilus-containing pneumococci. These multiple clades may be present in the immunogenic composition as separate polypeptides or may be fused as a single polypeptide chain. | 01-27-2011 |
20110097360 | STREPTOCOCCUS PNEUMONIAE PILUS ANTIGENS - Polypeptides from | 04-28-2011 |
20110166323 | CHIMERIC, HYBRID AND TANDEM POLYPEPTIDES OF MENINGOCOCCAL NMB1870 - NMB1870 is a protein in | 07-07-2011 |
20110243976 | COMPOSITIONS COMPRISING PNEUMOCOCCAL ANTIGENS - Disclosed herein are various combinations of pneumococcal polypeptides for use in immunisation. Also disclosed herein are pneumococcal polypeptides that may be useful as single antigens. These polypeptides may optionally be used in combination with pneumococcal saccharides. The antigens may be used in pneumococcal vaccines, but may also be used as components in vaccines for immunising against multiple pathogens. | 10-06-2011 |
20120020890 | STAPHYLOCOCCUS AUREUS PROTEINS AND NUCLEIC ACIDS - The invention provides proteins from | 01-26-2012 |
20120058143 | STAPHYLOCOCCUS AUREUS PROTEINS AND NUCLEIC ACIDS - The invention provides proteins from | 03-08-2012 |
20120076814 | COMBINATIONS OF PNEUMOCOCCAL RRGB CLADES - Pneumococcal pilus subunit RrgB has at least three clades. Serum raised against a given clade is active against pneumococci which express that RrgB clade, but is not active against strains which express one of the other two clades i.e. there is intra-clade cross-protection, but not inter-clade cross-protection. Thus an immunogenic composition can include at least two different clades of RrgB to improve strain coverage against pilus-containing pneumococci. These multiple clades may be present in the immunogenic composition as separate polypeptides or may be fused as a single polypeptide chain. | 03-29-2012 |
20120093868 | HAEMOPHILUS INFLUENZAE TYPE B - Polypeptides comprising various amino acid sequences derived from | 04-19-2012 |
20120128707 | STREPTOCOCCUS PNEUMONIAE PROTEINS AND NUCLEIC ACIDS - The invention provides proteins and nucleic acid sequences from | 05-24-2012 |
20120135024 | NEISSERIA MENINGITIDIS ANTIGENS AND COMPOSITIONS - The invention provides proteins from | 05-31-2012 |
20120148615 | POLYPEPTIDES FROM NON-TYPEABLE HAEMOPHILUS INFLUENZAE - Polypeptides comprising non-typeable | 06-14-2012 |
20120148616 | NEISSERIA MENINGITIDIS ANTIGENS AND COMPOSITIONS - The invention provides proteins from | 06-14-2012 |
20120156236 | NEISSERIA MENINGITIDIS ANTIGENS AND COMPOSITIONS - The invention provides proteins from | 06-21-2012 |
20120164166 | NEISSERIA MENINGITIDIS ANTIGENS AND COMPOSITIONS - The invention provides proteins from | 06-28-2012 |
20120177657 | FUSION PROTEINS COMPRISING CD4 MINIMAL MODULES AND METHODS OF USE THEREOF - Fusion proteins comprising CD4 minimal modules that bind to HIV Env polypeptides in a non-CD4 backbone are described. Also described are complexes of these fusion proteins with Env as well as methods of diagnosis, treatment and prevention using the polynucleotides and polypeptides are also provided. | 07-12-2012 |
20120207778 | NUCLEIC ACIDS AND PROTEINS FROM STREPTOCOCCUS GROUPS A AND B - The invention provides proteins from group B | 08-16-2012 |
20120219578 | NEISSERIAL ANTIGENIC PEPTIDES - This invention provides, among other things, proteins, polypeptides, and fragments thereof, derived from the bacteria | 08-30-2012 |
20120276129 | NEISSERIAL ANTIGENIC PEPTIDES - This invention provides, among other things, proteins, polypeptides, and fragments thereof, derived from the bacteria | 11-01-2012 |
20120283413 | CHIMERIC, HYBRID AND TANDEM POLYPEPTIDES OF MENINGOCOCCAL NMB1870 - NMB1870 is a protein in Neisseria meningitidis. Three families of NMB1870 are known. To increase the ability of a NMB1870 protein to elicit antibodies that are cross-reactive between the families, NMB1870 is engineered. Sequences can be substituted from one NMB1870 family into the corresponding position in another family. Proteins of NMB1870 sequences from different families can be joined to each other. | 11-08-2012 |
20130004616 | STREPTOCOCCUS THERMOPHILUS BACTERIUM - The present invention provides an improved | 01-03-2013 |
20130005667 | HETEROLOGOUS EXPRESSION OF NEISSERIAL PROTEINS - Alternative and improved approaches to the heterologous expression of the proteins of Neisseria meningitidis and | 01-03-2013 |
20130064846 | NEISSERIAL ANTIGENS - The invention provides proteins from | 03-14-2013 |
20130129740 | NUCLEIC ACIDS AND PROTEINS FROM STREPTOCOCCUS GROUPS A AND B - The invention provides proteins from group B | 05-23-2013 |
20130217859 | CHIMERIC, HYBRID AND TANDEM POLYPEPTIDES OF MENINGOCOCCAL NMB1870 - NMB 1870 is a protein in | 08-22-2013 |
20140127250 | STAPHYLOCOCCUS AUREUS PROTEINS AND NUCLEIC ACIDS - The invention provides proteins from | 05-08-2014 |
20140234363 | POLYPEPTIDES FROM NON-TYPEABLE HAEMOPHILUS INFLUENZAE - Polypeptides comprising non-typeable | 08-21-2014 |
20140242106 | STAPHYLOCOCCUS AUREUS PROTEINS AND NUCLEIC ACIDS - The invention provides proteins from | 08-28-2014 |
20140294885 | HETEROLOGOUS EXPRESSION OF NEISSERIAL PROTEINS - Alternative and improved approaches to the heterologous expression of the proteins of | 10-02-2014 |
20140302078 | HAEMOPHILUS INFLUENZAE TYPE B - Polypeptides comprising various amino acid sequences derived from | 10-09-2014 |
20140348868 | COMPOSITIONS COMPRISING PNEUMOCOCCAL ANTIGENS - Disclosed herein are various combinations of pneumococcal polypeptides for use in immunisation. Also disclosed herein are pneumococcal polypeptides that may be useful as single antigens. These polypeptides may optionally be used in combination with pneumococcal saccharides. The antigens may be used in pneumococcal vaccines, but may also be used as components in vaccines for immunising against multiple pathogens. | 11-27-2014 |
20140356389 | PROTEINS AND NUCLEIC ACIDS FROM MENINGITIS/SEPSIS-ASSOCIATED ESCHERICHIA COLI - Disclosed herein are various open reading frames from a strain of | 12-04-2014 |
20140363462 | HETEROLOGOUS EXPRESSION OF NEISSERIAL PROTEINS - Alternative and improved approaches to the heterologous expression of the proteins of | 12-11-2014 |
20150079124 | NEISSERIA MENINGITIDIS ANTIGENS AND COMPOSITIONS - The invention provides proteins from | 03-19-2015 |
20150086582 | NEISSERIA MENINGITIDIS ANTIGENS AND COMPOSITIONS - The invention provides proteins from | 03-26-2015 |