Tubbs, US
Christopher C. Tubbs, Temple Terrace, FL US
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20130068696 | Method and System for Treatment of Agricultural and Industrial Wastewaters Containing Solids and Nutrients - A method and system of treatment of agricultural and industrial wastewaters that contain high concentrations of suspended solids, nitrogen, and phosphorus compounds is disclosed. The method and system includes pre-treating the wastewater, controlling the amount of coagulants used, and controlling the mean velocity used for mixing, surface loading rate, and solids loading rate. The method and system functions as a sedimentation unit and gas flotation unit (solid/liquid separator). The pH of the effluent wastewater is stabilized within the separator by ensuring that there is sufficient alkalinity to buffer the wastewater. Sufficient gas is produced in the coagulation reactions to float and concentrate the solids, which results in as high as 99 percent reduction in suspended solids, a 96 percent reduction of the phosphorus concentration, and a 50 percent reduction of the nitrogen concentration in the effluent from the separator. | 03-21-2013 |
Clifford L. Tubbs, Miami, FL US
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20160128415 | PHYSIOLOGICAL AND NEUROLOGICAL MONITORING SPORTSWEAR - The present disclosure is directed to a physiological and neurological monitoring apparatus that monitors and satisfies the need for an improved buffer between the skull of a user and the impacting object so as to minimize the likelihood of neck and cranial injury. Further the helmet comprises a facemask for prevent concussions by absorbing the energy from an impact and redirecting the energy across the structure of the helmet shell. The embodiment comprises a helmet shell with elongated cheek guards and an elongated rear neck guard which follows the contour of the user's shoulder line and continues sufficiently below the head of said user to cover the rear neck of the user. These additions help prevent concussions by providing a larger surface of protection to especially weak areas that are prone to injury such as the rear of the neck and the lower jaw line. | 05-12-2016 |
Dallas Tubbs, Bakersfield, CA US
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20090024442 | SYSTEM AND METHODS FOR INCREASING SAFETY AND EFFICIENCY IN OIL FIELD OPERATIONS - Systems and methods for increasing safety and efficiency in oil field operations are provided. A monitor displays a map of an oil field that includes oil well objects, oil field facility objects, surface work crew objects, sub-surface work crew objects, and safety zones objects and work equipment rig objects. Each of the objects includes a date and location attribute. Each of the work crew objects are coded by a visual indicator to indicate a type of work, and selection of a work crew object produces a text box with a description of the associated work. A safety zone object is associated with the work crew objects and has a radius attribute that can be used to identify scheduling conflicts. A scheduling conflict is identified, and at least one work crew object is rescheduled via a domain-specific software application from which the crew object was extracted to remove the conflict. | 01-22-2009 |
20090125367 | SYSTEMS AND METHODS FOR DIAGNOSING PRODUCTION PROBLEMS IN OIL FIELD OPERATIONS - Systems and methods for diagnosing production problems in oil field operations are provided. A first video monitor displays an oil field diagnosis process flow chart that includes selectable objects such as Review Well Test Differences, Review Sliders, Review Bad Actors, and Perform Steam Flood Performance Check. Each selectable object is associated with one or more incompatible domain-specific software applications. One or more of the selectable objects are selected and one or more additional video monitors display reports extracted by a middle-ware software code segment layer from the associated domain-specific software applications. Oil wells having production problems are listed and problem oil wells are displayed on an oil field map. Any commonalities among the displayed problem oil wells indicative of a common cause of the production problems are visually identified. Work is scheduled in the associated domain-specific software applications sufficient to remedy the common cause. | 05-14-2009 |
Daniel L. Tubbs, Homeworth, OH US
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20160075382 | OPEN TOP CONTAINER WITH REINFORCED TOP RAIL - An open top container for transporting loads and a rail for strengthening an upper rim of the container's peripheral wall. The rail includes a U-shaped first region including first, second, and third legs secured end-to-end; and an F-shaped second region comprising a base with first and second arms extending downwardly from the base. The base is secured end-to-end with the third leg of the first region. A first strengthening rib extends outwardly from the first region and toward the container's wall. The first rib is laterally spaced from the wall but runs parallel thereto for substantially the entire length of the rail. A second rib vertically spaced from the first rib but parallel thereto may also extend outwardly from the first region and toward the container's wall. The rail increases progressively in thickness from the first leg to the second leg, then the third leg, and finally the base. | 03-17-2016 |
Dave Tubbs, Sandy, UT US
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20120158737 | SYSTEM AND METHOD FOR HYPERTEXT TRANSFER PROTOCOL LAYERED RECONSTRUCTION - HTTP layered reconstruction is disclosed. A database is queried to identify a location of a previously reconstructed HTML artifact file or packet data of a HTML file in a repository that stores packet data captured from a network. The reconstructed HTML file is analyzed. Links to external files are identified and the database is queried to identify a location of previously reconstructed artifact files or packet data of associated external files. The external files are reconstructed, as needed. A web page is then reconstructed based on the reconstructed HTML file and reconstructed external files, presenting a view of the web page as it originally appeared to a user. A user may specify which external file types to include and/or not include. New versions of external files may be obtained and indicated in the reconstructed web page when associated artifact files or packet data are not stored within the repository. | 06-21-2012 |
Donald A. Tubbs, Charlottesville, VA US
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20150128846 | Passive Alarm To Prevent Buried Infrastructure Damage - A method and apparatus are disclosed for preventing excavation damage to buried infrastructure. A plurality of excavation-sensing modules is buried near the buried infrastructure. The modules protect buried infrastructure by emitting dense clouds of highly visible gas when the modules are activated by impact with excavation equipment. In most cases the visible gas will be brightly colored and it may also have a strong odor and may produce a loud sound when the module is activated. The dense clouds of highly visible gas, the optional odor and loud sound alert construction crews or other workers that their excavation is nearing a protected underground structure. Once installed, no maintenance or active monitoring is required. In a preferred embodiment of the excavation-sensing module, the dense cloud of highly visible gas is produced by ignition of a smoke grenade within the module. In the preferred embodiment, the smoke grenade is ignited by the interaction of the excavator striking and breaking the buried module. Also in the preferred embodiment, the excavator will normally pull the ignited smoke grenade out of the buried module and to the surface increasing the visibility of the gas. Also in the preferred embodiment, a more reliable design for ignition of the smoke grenade is disclosed. | 05-14-2015 |
Douglas Tubbs, Gulf Breeze, FL US
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20150100381 | Method and System for Increasing the Percentage of Customers Realized from Smart Phone Advertising - A computerized method directed at smart phone users, that includes the step of utilizing a networked, computer device and software to provide “engagement services” via the video screens of the users' smart phones, can yield higher rates of customer conversions by configuring the computer device's software to provide: (a) a specialized interface that appears on the video screens of such smart phones, (b) prepared questions that appear on this interface and which are used in a dialog with a smart phone user to elicit the information necessary to establish the sales lead data of the smart phone user, (c) a real-time validation of the elicited information, and (d) prepared, follow-up responses, dependent upon the outcome of such validations, that also appear on the interface and which are provided so as to foster the continuation of the dialog and the collection of the necessary information. | 04-09-2015 |
Jason Tubbs, North Ogden, UT US
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20120292473 | Articulated Article Holder - An articulated article holder comprises an attachment base, configured to be attached to a support structure or to a component of a vehicle. A holding member is configured to receive and hold an article therein, the holding member being coupled to the attachment base and including two generally upright arms which collectively define a containment area therebetween. At least one of the upright arms includes an articulated joint formed or integrated therein to allow at least one segment of the arm to move between at least two differing positions. | 11-22-2012 |
Kelvin Tubbs, Rancho Palos Verdes, CA US
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20160112020 | COMBINED HIGH POWER RF/MICROWAVE AMPLIFIER WITH MULTIPLE POWER AMPLIFIER UNITS AND AUTOMATIC FAILURE PROTECTION - A high power RF or microwave amplifier may amplify an RF or microwave input signal. The high power RF or microwave amplifier may include an input signal divider (DIV) that has an input port that receives the RF or microwave input signal and that divides this input signal into multiple sub-input signals; multiple power amplifier units (PAUs), each having an input port that receives an RF or microwave signal, an output port that delivers an amplified version of the received RF or microwave signal, and an interface port; an interface control unit (ICU) that communicates with each PAU through its interface port; and an output signal switching combiner unit (SCU) that coherently sums the outputs of the on-line PAUs and delivers this to an output port. The ICU may set one or more of the PAUs to amplify one of the multiple sub-input signals (hereinafter referred to as on-line PAU in on-line mode); monitor each on-line PAU to verify that it is operating within one or more pre-determined PAU specifications; and upon detecting that one of the on-line PAUs is no longer operating within the one or more pre-determined PAU specifications (malfunctioning PAU), set the malfunctioning PAU not to amplify one of the multiple sub-input signals and not to be available to be switched to the on-line mode by the ICU (hereinafter referred to as off-line PAU in off-line mode). | 04-21-2016 |
Kemmons Tubbs, Mesa, AZ US
Patent application number | Description | Published |
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20090220908 | Dental and Medical Treatments and Procedures - A method treating a root canal in a tooth by introducing into the pulp chamber of a tooth and pulsing a laser light into the fluid reservoir so as to disintegrate pulp within the root canal without generation of any significant heat in said liquid fluid so as to avoid elevating the temperature of any of the dentin, tooth, or other adjacent tissue more than about 5° C. | 09-03-2009 |
20130153479 | INTEGRATED HIGH THROUGHPUT SYSTEM FOR THE ANALYSIS OF BIOMOLECULES - Described is an affinity microcolumn comprising a high surface area material, which has high flow properties and a low dead volume, contained within a housing and having affinity reagents bound to the surface of the high surface area material that are either activated or activatable. The affinity reagents bound to the surface of the affinity microcolumn further comprise affinity receptors for the integration into high throughput analysis of biomolecules. | 06-20-2013 |
20140193311 | INTEGRATED HIGH THROUGHPUT SYSTEM FOR THE ANALYSIS OF BIOMOLECULES - Described is an affinity microcolumn comprising a high surface area material, which has high flow properties and a low dead volume, contained within a housing and having affinity reagents bound to the surface of the high surface area material that are either activated or activatable. The affinity reagents bound to the surface of the affinity microcolumn further comprise affinity receptors for the integration into high throughput analysis of biomolecules. | 07-10-2014 |
20160003841 | INTEGRATED HIGH THROUGHPUT SYSTEM FOR THE ANALYSIS OF BIOMOLECULES - Described is an affinity microcolumn comprising a high surface area material, which has high flow properties and a low dead volume, contained within a housing and having affinity reagents bound to the surface of the high surface area material that are either activated or activatable. The affinity reagents bound to the surface of the affinity microcolumn further comprise affinity receptors for the integration into high throughput analysis of biomolecules. | 01-07-2016 |
Kemmons A. Tubbs, Mesa, AZ US
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20090197284 | Analysis of Proteins from Biological Fluids Using Mass Spectrometric Immunoassay - Presented herein are methods, devices and kits for the mass spectrometric immunoassay (MSIA) of proteins present in complex biological fluids or extracts. Pipettor tips containing porous solid supports that are covalently derivatized with affinity ligand and used to extract specific proteins and their variants from various biological fluids. Nonspecifically bound compounds are rinsed from the extraction devices using a series of buffer and water rinses, after which the wild type protein (and/or its variants) are eluted directly onto a target in preparation for analysis such as matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS). Mass spectrometry of the eluted sample then follows with the retained proteins identified via accurate molecular mass determination. Protein and variant levels can be determined using quantitative methods in which the protein/variant signals are normalized to signals of internal reference standard species (either doped into the samples prior to the MSIA analysis, or other endogenous protein co-extracted with the target proteins) and the values compared to a working curves constructed from samples containing known concentrations of the protein or variants. Such MSIA devices, kits and methods have significant application in the fields of; basic research and development, proteomics, protein structural characterization, drug discovery, drug-target discovery, therapeutic monitoring, clinical monitoring and diagnostics, as well as in the high throughput screening of large populations to establish and recognize protein/variant patterns that are able to differentiate healthy from diseased states. | 08-06-2009 |
20100181239 | Integrated High Throughput System for the Analysis of Biomolecules - Described is an affinity microcolumn comprising a high surface area material, which has high flow properties and a low dead volume, contained within a housing and having affinity reagents bound to the surface of the high surface area material that are either activated or activatable. The affinity reagents bound to the surface of the affinity microcolumn further comprise affinity receptors for the integration into high throughput analysis of biomolecules. | 07-22-2010 |
20100267069 | ANALYSIS OF PROTEINS FROM BIOLOGICAL FLUIDS USING MASS SPECTROMETRIC IMMUNOASSAY - Presented herein are methods, devices and kits for the mass spectrometric immunoassay (MSIA) of proteins present in complex biological fluids or extracts. Pipettor tips containing porous solid supports that are covalently derivatized with affinity ligand and used to extract specific proteins and their variants from various biological fluids. Nonspecifically bound compounds are rinsed from the extraction devices using a series of buffer and water rinses, after which the wild type protein (and/or its variants) are eluted directly onto a target in preparation for analysis such as matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS). Mass spectrometry of the eluted sample then follows with the retained proteins identified via accurate molecular mass determination. Protein and variant levels can be determined using quantitative methods in which the protein/variant signals are normalized to signals of internal reference standard species (either doped into the samples prior to the MSIA analysis, or other endogenous protein co-extracted with the target proteins) and the values compared to a working curves constructed from samples containing known concentrations of the protein or variants. Such MSIA devices, kits and methods have significant application in the fields of; basic research and development, proteomics, protein structural characterization, drug discovery, drug-target discovery, therapeutic monitoring, clinical monitoring and diagnostics, as well as in the high throughput screening of large populations to establish and recognize protein/variant patterns that are able to differentiate healthy from diseased states. | 10-21-2010 |
20100267581 | HIGH THROUGHPUT INTEGRATED MICROFLUIDIC SYSTEM AND DEVICE - A microfluidic system and device capable of high throughput which includes a multi-channel micro-column having a high surface area material having at least one affinity reagent bound thereto contained within a housing. The structure of the housing and/or the multi-channel micro-column is of a sufficient size and configuration to enable capture and purification of an analyte contained within a sample and one or more of binding of a reporter molecule to the analyte and a substrate chemical reaction with the analyte to all take place within the housing and/or the multi-channel micro-column. | 10-21-2010 |
20100330539 | PERIODONTAL TREATMENT SYSTEM AND METHOD - Methods and apparatuses for treating a root canal in a tooth or hard and/or soft tissue within a tooth and surrounding tissues by pulsing a laser light into a reservoir, preferably after introducing liquid fluid into the reservoir, so as to disintegrate, separate, or otherwise neutralize pulp, plaque, calculus, and/or bacteria within and adjacent the fluid reservoir without elevating the temperature of any of the dentin, tooth, bones, gums, other soft tissues, other hard tissues, and any other adjacent tissue more than about 5° C. | 12-30-2010 |
20110192778 | INTEGRATED HIGH THROUGHPUT SYSTEM FOR THE ANALYSIS OF BIOMOLECULES - Described is an affinity microcolumn comprising a high surface area material, which has high flow properties and a low dead volume, contained within a housing and having affinity reagents bound to the surface of the high surface area material that are either activated or activatable. The affinity reagents bound to the surface of the affinity microcolumn further comprise affinity receptors for the integration into high throughput analysis of biomolecules. | 08-11-2011 |
20110269099 | DENTAL AND MEDICAL TREATMENTS AND PROCEDURES - A method treating a root canal in a tooth by introducing into the pulp chamber of a tooth and pulsing a laser light into the fluid reservoir so as to disintegrate pulp within the root canal without generation of any significant heat in said liquid fluid so as to avoid elevating the temperature of any of the dentin, tooth, or other adjacent tissue more than about 5° C. | 11-03-2011 |
20120085692 | INTEGRATED HIGH THROUGHPUT SYSTEM FOR THE ANALYSIS OF BIOMOLECULES - Described is an affinity microcolumn comprising a high surface area material, which has high flow properties and a low dead volume, contained within a housing and having affinity reagents bound to the surface of the high surface area material that are either activated or activatable. The affinity reagents bound to the surface of the affinity microcolumn further comprise affinity receptors for the integration into high throughput analysis of biomolecules. | 04-12-2012 |
20130143180 | PERIODONTAL TREATMENT SYSTEM AND METHOD - Methods and apparatuses for treating a root canal in a tooth or hard and/or soft tissue within a tooth and surrounding tissues by pulsing a laser light into a reservoir, preferably after introducing liquid fluid into the reservoir, so as to disintegrate, separate, or otherwise neutralize pulp, plaque, calculus, and/or bacteria within and adjacent the fluid reservoir without elevating the temperature of any of the dentin, tooth, bones, gums, other soft tissues, other hard tissues, and any other adjacent tissue more than about 5° C. | 06-06-2013 |
20140004020 | STAND FOR USE WITH AFFINITY CAPTURE | 01-02-2014 |
20140087333 | PERIODONTAL TREATMENT SYSTEM AND METHOD - Methods and apparatuses for treating a root canal in a tooth or hard and/or soft tissue within a tooth and surrounding tissues by pulsing a laser light into a reservoir, preferably after introducing liquid fluid into the reservoir, so as to disintegrate, separate, or otherwise neutralize pulp, plaque, calculus, and/or bacteria within and adjacent the fluid reservoir without elevating the temperature of any of the dentin, tooth, bones, gums, other soft tissues, other hard tissues, and any other adjacent tissue more than about 5° C. | 03-27-2014 |
20140220511 | PERIODONTAL TREATMENT SYSTEM AND METHOD - The specification discloses embodiments and other information concerning methods, systems, and apparatus in accordance with aspects of the subject invention for treating diseased root canals in teeth and other dental condition, such as periodontitis and the like wherein a laser light is pulsed from a laser fiber optic tip into liquid contained in a reservoir or other space within the canal, periodontal sulcus/pocket, or other dental space immersing the area in need of treatment so as to disintegrate, separate, or otherwise neutralize pulp, plaque, calculus, bacteria, and other microbes, thus annihilating and particleizing undesirable material within the liquid in the reservoir by the action of relatively intense, photoacoustic micro-pressure waves propagating throughout the liquid as a result of the laser light pulses emitted into the liquid from the tip, thereby enabling easy removal of the particles by finely dispersing the same in the liquid and then flushing the particle-laden liquid from the area by hydraulic swirling actions associated with the pulsing light and through ensuing antiseptic rinses, all without elevating the temperature of nearby dentin, tooth, bones, gums, and/or other soft/hard adjacent tissues more than about 5° C. so as to avoid or eliminate harmful effects of localized heating of the same. | 08-07-2014 |
Lenny Tubbs, Lawrenceville, GA US
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20120124928 | Fire Stop and Method of Use Thereof - A fire stop dimensioned to fit a selected size opening. The fire stop comprises end plates, a central shaft member retaining the end plates apart from one another, and a core between the end plates that comprises fire putty and mineral wool. The thickness and density of the mineral wool layer and/or the fire putty layer are chosen to achieve a particular fire rating within the constraints of the overall dimensional thickness of the slab. The fire stop has a low profile rendering it non-obstructing, can be inserted by a single installer from above a floor slab or into a wall, and further can be removed for inspection and/or replacement as needed. The fire putty layer swells under heat filling remaining gaps between the fire stop and the opening. | 05-24-2012 |
Nick Tubbs, Beaverton, OR US
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20100206693 | LONG AXIS COMPONENT LOADER - A component loader orients a component along its long-axis for transfer from a rotatable load plate. The load plate has an outer peripheral edge and an upper surface inclined from a horizontal plane. Slots on the upper surface terminate at the outer edge of the load plate and are sized to receive at least one elongate chip lying with its long axis perpendicular to the axis of the load plate and in parallel with radius of the load plate. An outer wall conforms to the curvature of the outer edge and is mounted adjacent thereto. A transfer slot extends axially from and into the upper surface of the load plate on outer ends of the slots and terminates at the outer edge of the load plate. Each transfer slot is shaped so that a chip descending therein from a slot has a ninety degree rotation about the long axis. | 08-19-2010 |
Nick A. Tubbs, Beaverton, OR US
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20090237096 | Compensation Tool For Calibrating An Electronic Component Testing Machine To A Standardized Value - A compensation tool and process is provided for calibrating each test position located at a plurality of test modules of an electronic testing machine to a standardized value. Each test module is located on an angularly spaced radial line extending from an associated central axis and has a plurality of contacts for testing electronic components. The compensation tool can include a body having an axis of rotation coaxially alignable with the central axis for rotation to different angular positions, and a component-support member operably associated with the body for indexing movement to selectively align with different contacts associated with each test position located at each of the plurality of test modules. The component-support member can include a pocket for receiving an electronic component with terminated ends extending outwardly to allow electrical contact and testing of each test position located at each the plurality of test modules. | 09-24-2009 |
20130014473 | CONFIGURATIONS OF ELECTRONIC COMPONENT-CARRYING APERTURES IN A TERMINATION BELT - A miniature component carrier includes a thin, resilient mask through which are formed multiple spaced-apart apertures each of which is sized and shaped to compliantly receive and hold a miniature component in a controlled orientation during termination processing such that the side margins of the aperture primarily contact and grip the corner regions of the miniature component. At least some of the apertures have side margins that form rhomboidal or elliptical apertures. The shape and size of the multiple spaced-apart apertures confine within an operational tolerance contact between the side margins of the aperture and the side or end wall surfaces of the electronic component. This reduces mechanical damage to the side and end wall surfaces that results from their contact with the side margins during receipt and gripping of the miniature component in the aperture. | 01-17-2013 |
20140116922 | CONFIGURATIONS OF APERTURES IN A MINIATURE ELECTRONIC COMPONENT CARRIER MASK - A miniature component carrier includes a thin, resilient mask through which are formed multiple spaced-apart apertures each of which is sized and shaped to compliantly receive and hold a miniature component in a controlled orientation during termination processing such that the side margins of the aperture primarily contact and grip the corner regions of the miniature component. At least some of the apertures have side margins that form rhomboidal or elliptical apertures. The shape and size of the multiple spaced-apart apertures confine within an operational tolerance contact between the side margins of the aperture and the side or end wall surfaces of the electronic component. This reduces mechanical damage to the side and end wall surfaces that results from their contact with the side margins during receipt and gripping of the miniature component in the aperture. | 05-01-2014 |
Orain Tubbs, Beaumont, TX US
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20130284872 | PIPELINE MAT - Systems and methods which provide improved pipeline mats are provided herein. Such mats may include one or more of a plurality of the inventive features. For example, some embodiments provide for replaceable top surfaces which allow for portions of the mat to be replaced if in need of repairs, e.g. after excessive wear and tear, rotting, and the like. Further, embodiments may include a built-in air wick channel which allows for airflow to travel between stacked mats, thereby reducing the potential for a mat to rot. Some embodiments may also include a structure which allows for the mat to be moved using a forklift. Such structure may include grouser strips which help direct the forklift while also protecting the top surface from wear. Additionally, such structure may include built-in chocks disposed on the lower surface of the mat. These chocks may also facilitate the air wick channel. | 10-31-2013 |
20140183319 | Synthetic Laminated Mat - An improved laminated mat which comprises synthetic materials are provided for herein. Embodiments may include a plurality of synthetic boards disposed adjacent to each other to form a top surface. Such a top surface may be configured such that individual boards are replaceable in the event of defects, wear and the like. The top surface may be attached to a lower support layer. This layer may also include a plurality of synthetic boards arranged in a cross-hatched manner with respect to the top surface. | 07-03-2014 |
20140186573 | Synthetic Laminated Mat - An improved laminated mat which comprises synthetic materials are provided for herein. Embodiments may include a plurality of synthetic boards disposed adjacent to each other to form a top surface. Such a top surface may be configured such that individual boards are replaceable in the event of defects, wear and the like. The top surface may be attached to a lower support layer. This layer may also include a plurality of synthetic boards arranged in a cross-hatched manner with respect to the top surface. | 07-03-2014 |
Raymond Tubbs, Cleveland, OH US
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20140178869 | DETECTION OF IMMUNOGLOBULIN LIGHT CHAIN RESTRICTION BY RNA IN SITU HYBRIDIZATION - The invention provides a method for detecting immunoglobulin light chain restriction and clonality in B cells by obtaining a sample of B cells from a subject; conducting a duplex in situ hybridization assay on the sample using (i) at least one probe set which is designed to specifically hybridize to immunoglobulin kappa chain constant region (IGKCR) RNA; and (ii) at least one probe set which is designed to specifically hybridize to immunoglobulin lambda chain constant region (IGLCR) RNA; detecting signal associated with hybridized IGKCR probe and signal associated with hybridized IGLCR probe in a population of B cells in the sample; and determining a pattern of signal associated with hybridized IGKCR probe and hybridized IGLCR probe within individual cells in the B cell population, wherein the pattern of signal within individual cells indicates the presence or absence of light chain restriction and clonality of the B cells. | 06-26-2014 |
20150347702 | Image Analysis for Breast Cancer Prognosis - Heterogeneity for biomarkers in a tissue sample can be calculated. A heterogeneity score can be combined with an immunohistochemistry combination score to provide breast cancer recurrence prognosis. Heterogeneity can be based on percent positivity determinations for a plurality of biomarkers according to how many cells in the sample stain positive. An immunohistochemistry combination score can be calculated. An imaging tool can support a digital pathologist workflow that includes designating fields of view in an image of the tissue sample. Based on the fields of view, a heterogeneity metric can be calculated and combined with an immunohistochemistry combination score to generate a breast cancer recurrence prognosis score. | 12-03-2015 |
Robert Tubbs, Burbank, CA US
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20080290545 | Method for accommodating the use of chemicals that contain low amounts of VOC in an existing device where chemicals that contained high levels of VOC had previously been used and resultant product - This method to allow the use of low VOC (volatile organic compounds) solvents in blanket cleaning operations and the resultant product that is produced by this method involves the retrofitting of currently existing seals on printing press so that operators can use low VOC solvents in place of high VOC solvents. High VOC solvents are harmful to the atmosphere and humans alike. As VOC are lighter than the surrounding air, humans are subjected to inhalation of these harmful vapors which cause respiratory and other health ailments. The VOC continue to rise, mixing with nitrogen oxides, until they reach the troposphere forming thick layers of ozone or smog. The current movement of municipalities to limit the use of high VOC solvents have lead printers and others to use low VOC solvents which are inherently less evaporative than high VOC solvents. This lack of evaporation causes problems with having to handle greater volumes of waste to handle and dispose properly. Catch pans and basins designed to work in high VOC applications are insufficiently engineered to handle this increased waste and seals that are sized to fit the catch pans and basins are designed to be permeable to allow for the evaporation of the VOC. This method creates an impermeable seal with similar sizing to retrofit the existing seal allowing the user to simply change the seal versus changing the entire catch pan. | 11-27-2008 |