Tsuji, US
Craig Tsuji, San Jose, CA US
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20130046318 | Surgical Instrument With Commonly Actuated Robotic and Manual Features - An instrument including an end effector at a distal end; an actuator mechanism at a proximal end, the actuator mechanism including a first valve, a robotic control coupled to the first valve, and a manual control coupled to the first valve is provided. The instrument may further include a transport shaft between the actuator mechanism and the end effector, the transport shaft including a cavity, coupled to the first valve, facilitating material transport along the transport shaft, the first valve having an actuating axis perpendicular to a rotational axis of the robotic control. A method for using an instrument as above is also provided. | 02-21-2013 |
Craig Tsuji US
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20110028970 | ELECTROSURGICAL SYSTEMS AND METHODS FOR REMOVING AND MODIFYING TISSUE - The present invention provides systems, apparatus and methods for selectively applying electrical energy to body tissue in order to ablate, contract, coagulate, or otherwise modify a tissue or organ of a patients. An electrosurgical apparatus includes an electrode support bearing an active electrode in the form of a plasma blade or hook having an active edge and first and second blade sides. The active edge is adapted for severing a target tissue via localized molecular dissociation of tissue components. The first and second blade sides are adapted for engaging against, and coagulating, the severed tissue. A method of the present invention comprises positioning an electrosurgical probe adjacent to the target tissue so that a blade- or hook-like active electrode is brought into at least close proximity to the target tissue in the presence of an electrically conductive fluid. A high frequency voltage is applied between the active electrode and a return electrode to effect cool ablation or other modification of the target tissue. During application of the high frequency voltage, the electrosurgical apparatus may be translated, reciprocated, or otherwise manipulated such that the active edge is moved with respect to the tissue. The present invention volumetrically ablates or otherwise modifies the target tissue with minimal or no damage to surrounding, non-target tissue. | 02-03-2011 |
Craig K. Tsuji, Santa Clara, CA US
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20080243169 | SYSTEM AND METHOD FOR ESTABLISHING VASCULAR ACCESS - Systems, kits, and methods for establishing vascular access are described. A system typically includes a radially expandable sleeve, a dilator, and a guidewire. The methods comprise positioning the guidewire through an initial tissue tract, passing the radially expandable sleeve over the guidewire through the tissue tract to a target blood vessel, and thereafter passing the dilator over the guidewire and through the radially expandable sleeve to effect radial expansion of the sleeve. Use of the sleeve reduces the risk of injuring tissue surrounding the tissue tract by lessening the axial forces imparted to the tissue. Kits comprise at least the radially expandable sleeve together with instructions for use. | 10-02-2008 |
Frederick I. Tsuji, San Diego, CA US
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20090123969 | NOVEL FLUORESCENT PROTEIN AND GENE ENCODING THE SAME - The present invention provides a novel fluorescent protein the wavelength of the maximum of the fluorescence of which exists in a wavelength side longer than 510 nm, and which exhibits yellow fluorescence or yellowish green fluorescence and can be expressed in a heterogeneous cell, and a gene encoding the same, wherein the fluorescent protein has an amino acid sequence as set forth in SEQ ID NO: 1 and it is a fluorescent protein derived from a copepod taxonomically classified to | 05-14-2009 |
Kosei Tsuji US
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20150333590 | CONNECTION TERMINAL, CONNECTION TERMINAL UNIT, AND MOTOR - An objective of the present invention is to provide a connection terminal in which the number of parts is reduced and a contact failure hardly occurs. A connection terminal is conducted to a windings wound around tooth of a stator having a cylindrical shape. The connection terminal includes an insertion part that is inserted in a concave part formed in the stator of a motor and a connection part that extends from the insertion part. In the insertion part, a contact part that comes into contact with an end part of the winding when the insertion part is inserted in the concave part, is formed. The insertion part and the connection part are integrally formed. | 11-19-2015 |
Masao Tsuji, Mesa, AZ US
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20080291679 | VENTILATION FAN AND LIGHT - A ventilation fan and light ( | 11-27-2008 |
Moriya Tsuji, New York, NY US
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20090117089 | GLYCOLIPIDS AND ANALOGUES THEREOF AS ANTIGENS FOR NK T CELLS - This invention relates to immunogenic compounds which may serve as ligands for NKT (natural killer T) cells and to methods of use thereof in modulating immune responses. | 05-07-2009 |
20100233207 | C-GLYCOLIPIDS WITH ENHANCED TH-1 PROFILE - The invention is directed to novel synthetic C-glycolipids that selectively induce a ThI-type immune response characterized by enhanced IL-12 secretion and increased activation of dendritic cells. The compounds of the invention are thereby useful in treating infections, cancers, cell proliferative disorders, and autoimmune diseases, both directly and as adjuvants. | 09-16-2010 |
20110086053 | Glycolipids And Analogues Thereof As Antigens For NKT Cells - This invention relates to immunogenic compounds which serve as ligands for NKT (natural killer T) cells and to methods of use thereof in modulating immune responses. | 04-14-2011 |
20120213814 | MODIFICATION OF RECOMBINANT ADENOVIRUS WITH IMMUNOGENIC PLASMODIUM CIRCUMSPOROZOITE PROTEIN EPITOPES - The present disclosure relates to adenovirus protein modifications to augment immune response to a transgene of a recombinant adenovirus and to circumvent pre-existing anti-adenovirus immunity. Some embodiments are directed to a recombinant adenovirus derived from a recombinant adenovirus plasmid vector, wherein the recombinant adenovirus plasmid vector comprises a nucleotide sequence encoding a | 08-23-2012 |
20120258142 | GLYCOLIPIDS AND ANALOGUES THEREOF AS ANTIGENS FOR NKT CELLS - This invention relates to immunogenic compounds which serve as ligands for NKT (natural killer T) cells and to methods of use thereof in modulating immune responses. | 10-11-2012 |
20120288525 | PHARMACEUTICAL COMPOSITIONS COMPRISING ATTENUATED PLASMODIUM SPOROZOITES AND GLYCOLIPID ADJUVANTS - Disclosed herein are pharmaceutical compositions comprising | 11-15-2012 |
20140120138 | PHARMACEUTICAL COMPOSITIONS COMPRISING ATTENUATED PLASMODIUM SPOROZOITES AND GLYCOLIPID ADJUVANTS - Disclosed herein are pharmaceutical compositions comprising | 05-01-2014 |
20140186378 | GLYCOLIPIDS AND ANALOGUES THEREOF AS ANTIGENS FOR NKT CELLS - This invention relates to immunogenic compounds which serve as ligands for NKT (natural killer T) cells and to methods of use thereof in modulating immune responses. | 07-03-2014 |
Shingo Tsuji, National City, CA US
Takemasa Tsuji, Williamsville, NY US
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20150368349 | Anti-GITR Antibodies and Methods of Use Thereof - The present disclosure provides antibodies that specifically bind to human glucocorticoid-induced TNFR family related receptor (GITR) and compositions comprising such antibodies. In a specific aspect, the antibodies specifically bind to human GITR and modulate GITR activity, e.g., enhance, activate or induce GITR activity, utilizing such antibodies. The present disclosure also provides methods for treating disorders, such as cancer and infectious diseases, by administering an antibody that specifically binds to human GITR and modulates GITR activity e.g., enhances, activates or induces GITR activity. | 12-24-2015 |
Takemasa Tsuji, New York, NY US
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20120328660 | IMMUNOGENIC COMPOSITIONS USEFUL IN PROVOKING AN INTEGRATED RESPONSE TO TUMOR ANTIGENS - The invention relates to an immunogenic composition and its use. It comprises “OLPs,” or overlapping peptides, derived from a longer, tumor antigen, in combination with polyICLC, and Montanide. | 12-27-2012 |
20140255436 | IMMUNOGENIC COMPOSITIONS USEFUL IN PROVOKING AN INTEGRATED RESPONSE TO TUMOR ANTIGENS - The invention relates to an immunogenic composition and its use. It comprises “OLPs,” or overlapping peptides, derived from a longer, tumor antigen, in combination with polyICLC, and Montanide. | 09-11-2014 |
Toshiya Tsuji, San Diego, CA US
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20130245028 | TREATMENT OF CANCER WITH TOR KINASE INHIBITORS - Provided herein are methods for treating or preventing ETS overexpressing castration-resistant prostate cancer, comprising administering an effective amount of a TOR kinase inhibitor to a patient having ETS overexpressing castration-resistant prostate cancer. | 09-19-2013 |
20140113904 | TREATMENT OF CANCER WITH TOR KINASE INHIBITORS - Provided herein are methods for treating or preventing prostate cancer, comprising administering an effective amount of a TOR kinase inhibitor to a patient having prostate cancer. | 04-24-2014 |
20140314673 | TREATMENT OF CANCER WITH DIHYDROPYRAZINO-PYRAZINES - Provided herein are methods for treating or preventing head and neck squamous cell carcinoma characterized by deletion of chromosome 11q22 or loss of ataxia telangiectasia mutated expression, comprising administering an effective amount of a dihydropyrazino-pyrazine to a patient having head and neck squamous cell carcinoma characterized by deletion of chromosome 11q22 or loss of ataxia telangiectasia mutated expression. | 10-23-2014 |
20140315900 | METHODS FOR TREATING CANCER USING DIHYDROPYRAZINO-PYRAZINE COMPOUND COMBINATION THERAPY - Provided herein are methods for treating or preventing a cancer, comprising administering an effective amount of a Dihydropyrazino-Pyrazine Compound and an effective amount of an androgen receptor antagonist to a patient having a cancer. | 10-23-2014 |
20140315907 | TREATMENT OF CANCER WITH DIHYDROPYRAZINO-PYRAZINES - Provided herein are methods for treating or preventing chronic lymphocytic leukemia, comprising administering an effective amount of a Dihydropyrazino-Pyrazine Compound to a patient having chronic lymphocytic leukemia. | 10-23-2014 |
Wayne Tsuji, Seattle, WA US
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20140302036 | PROTEINS SPECIFIC FOR BAFF AND B7RP1 - Described herein are bispecific proteins specific for BAFF and B7RP1, nucleic acids encoding such proteins, methods of making such proteins, and uses for such proteins. | 10-09-2014 |
Yoichi Tsuji, San Jose, CA US
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20080215534 | COST-BASED SUBQUERY CORRELATION AND DECORRELATION - Techniques are provided that determine that a query includes at least one subquery that may be correlated or decorrelated. An internal representation of the query that represents the subquery in both correlated and decorrelated form is generated, wherein the internal representation includes at least one virtual table. | 09-04-2008 |
20080243761 | METHOD AND SYSTEM FOR QUANTIFYING A DATA PAGE REPETITION PATTERN FOR A DATABASE INDEX IN A DATABASE MANAGEMENT SYSTEM - A method and system are presented for quantifying a data page repetition pattern for a database index in a database management system. In one embodiment, the method includes identifying a database index to provide a basis for collecting a data page repetition statistic, the database index having a database index key. The method may also include collecting the data page repetition statistic based on the database index key, wherein the data page repetition statistic quantifies a data page repetition pattern associated with database queries that reference sequential entries of the database index. The method may further include optimizing a data page access process based on the data page repetition statistic. In a further embodiment, the method may utilize both cluster ratio and data page repetition statistics to evaluate data page I/O and CPU cost. | 10-02-2008 |