Towne, US
Anthony Towne, Windsor, CT US
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20110139266 | ADJUSTABLE PLUGS FOR FLUID FLOW-SPLIT ACCURACY - A flow splitter for accurately dividing fluid flow into different outlets includes a splitter valve and a calibration member. The calibration member blocks a portion of fluid flow to reduce differences in the divided fluid flows. | 06-16-2011 |
Brian Towne, Zebulon, NC US
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20130283538 | MATTRESS ASSEMBLIES AND COMPONENTS EMPLOYING PASSAGEWAYS FOR VENTILATION AND AIRFLOW - Embodiments disclosed herein include mattress assemblies and components employing passageways for ventilation and airflow. A mattress may contain a mattress core to provide cushioning and support. For example, the mattress core may comprise an innerspring, air bladder(s), and/or foam layer(s). A mattress assembly may include a foam base and/or at least one foam side support member to at least partially surround a mattress core to provide cushioning and structure. The foam base and/or at least one foam side support member may include at least one passageway for facilitating diffusion and air exchange between an exterior environment and an interior space of the enclosure containing the mattress core. In this manner, as stagnant air and humidity developing in the mattress core may be avoided or reduced from the mattress core, which may otherwise cause unhealthy conditions or unpleasant odors for users. | 10-31-2013 |
Charles Towne, Shrewsbury, MA US
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20130274146 | CAPTURE REACTIONS - The invention generally relates to methods of performing a capture reaction. In certain embodiments, the method involves obtaining a nucleic acid, fragmenting the nucleic acid, and capturing a target sequence on the nucleic acid fragment using a capture moiety, such as a molecular inversion probe. | 10-17-2013 |
Christopher L. Towne, San Francisco, CA US
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20160030765 | SYSTEM AND METHOD FOR OPTOGENETIC THERAPY - One embodiment is directed to a system for controllably managing pain in the afferent nervous system of a patient having a targeted tissue structure that has been genetically modified to have light sensitive protein, comprising a light delivery element configured to direct radiation to at least a portion of a targeted tissue structure; a light source configured to provide light to the light delivery element; and a controller operatively coupled to light source; wherein the targeted tissue structure comprises a sensory neuron of the patient; and wherein the controller is configured to be automatically operated to illuminate the targeted tissue structure with radiation such that a membrane potential of cells comprising the targeted tissue structure is modulated at least in part due to exposure of the light sensitive protein to the radiation. | 02-04-2016 |
Craig A. Towne, Canandaigua, NY US
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20120218575 | Handprint Recognition Test Deck - A system and method for creating one of a plurality of test decks to qualify and test forms processing systems, including preparing a handprint snippet data base containing labeled handprint image snippets representing a unique hand, preparing a form description file and a data content file, selecting handprint snippets from the handprint snippet data base to formulate a form using the data content file, creating a form image using the selected snippets according to the form description file and printing the form image. | 08-30-2012 |
Dave Towne, San Carlos, CA US
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20140324624 | WINE RECOMMENDATION SYSTEM AND METHOD - A computer readable medium comprises instructions, which when executed by a data processor of a portable electronic device, cause the data processor to obtain a list of wines available at a commercial establishment; and identify at least one attribute associated with each wine included on the list of wines. The instructions further cause the data processor to, for each wine included on the list of wines, determine a score indicative of a likelihood that the user will purchase the wine on the basis of the at least one attribute and at least one of a characteristic associated with the user and a preference input by the user. Based on the score, the instructions further cause the data processor to identify at least one recommended wine for recommendation to the user; and present the at least one recommended wine on a display interface of the portable electronic device. | 10-30-2014 |
Gerald Towne, Haverhill, MA US
Patent application number | Description | Published |
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20140132372 | INTERMODULATION DISTORTION REDUCTION SYSTEM USING INSULATED TUNING ELEMENTS - A coaxial cavity resonator filter has a hollow cavity and a post having desired dimensions for achieving desired filter characteristics. A tuning element is supported within a metallic opening and is configured to electromagnetically interact with the post. The tuning element has a conductive core element where the orientation of the tuning element with the cavity is adjusted so as to achieve the desired filter characteristic. An insulator is configured to cover a portion of the conductive core element of the tuning element, at a location where the tuning element and the metallic opening interact. A portion of the insulator is threaded so as to allow the conductive core element vary its orientation within the cavity without contacting the metallic opening. | 05-15-2014 |
Jay M. Towne, Newbury, NH US
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20090102469 | Methods and Apparatus for Vibration Detection - Apparatus for detecting vibration of an object adapted to rotate includes one or more vibration processors selected from: a direction-change processor adapted to detect changes in a direction of rotation of the object, a direction-agreement processor adapted to identify a direction of rotation of the object in at least two channels and identify an agreement or disagreement in direction of rotation identified by the at least two channels, a phase-overlap processor adapted to identify overlapping signal regions in signals associated with the rotation of the object, and a running mode processor adapted to identify an unresponsive output signal from at least one of the at least two channels. A method for detecting the vibration of the object includes generating at least one of a direction-change output signal with the direction-change processor, a direction-agreement output signal with the direction-agreement processor, a phase-overlap output signal with the phase-overlap processor, and a running-mode-vibration output signal with the running-mode processor, each indicative of the vibration the object. | 04-23-2009 |
20090153137 | Methods and Apparatus for Vibration Detection - Apparatus for detecting vibration of an object adapted to rotate includes one or more vibration processors selected from: a direction-change processor adapted to detect changes in a direction of rotation of the object, a direction-agreement processor adapted to identify a direction of rotation of the object in at least two channels and identify an agreement or disagreement in direction of rotation identified by the at least two channels, a phase-overlap processor adapted to identify overlapping signal regions in signals associated with the rotation of the object, and a running mode processor adapted to identify an unresponsive output signal from at least one of the at least two channels. A method for detecting the vibration of the object includes generating at least one of a direction-change output signal with the direction-change processor, a direction-agreement output signal with the direction-agreement processor, a phase-overlap output signal with the phase-overlap processor, and a running-mode-vibration output signal with the running-mode processor, each indicative of the vibration the object. | 06-18-2009 |
Jay M. Towne, Bow, NH US
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20140375312 | Systems and Methods for Providing Signal Encoding Representative of a Signature Region in a Target - A magnetic field sensor and associated method provide an output signal with an identifiable encoding to indicate when a signature region in a moving target proximate to the magnetic field sensor passes by the magnetic field sensor. | 12-25-2014 |
Jennifer E. Towne, Seattle, WA US
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20080241096 | IL-1 family variants - The present invention provides compositions and methods relating to IL-1Rrp2 requiring proteins. | 10-02-2008 |
20120020918 | IL-1 FAMILY VARIANTS - The present invention provides compositions and methods relating to IL-1Rrp2 requiring proteins. | 01-26-2012 |
20130004501 | HUMAN IL-23 ANTIGEN BINDING PROTEINS - Antigen binding proteins that bind to human IL-23 protein are provided. Nucleic acids encoding the antigen binding protein, vectors, and cells encoding the same as well as use of IL-23 antigen binding proteins for diagnostic and therapeutic purposes are also provided. | 01-03-2013 |
20130336926 | IL-1 FAMILY VARIANTS - The present invention provides compositions and methods relating to IL-1Rrp2 requiring proteins. | 12-19-2013 |
20140212428 | HUMAN IL-23 ANTIGEN BINDING PROTEINS - Antigen binding proteins that bind to human IL-23 protein are provided. Nucleic acids encoding the antigen binding protein, vectors, and cells encoding the same as well as use of IL-23 antigen binding proteins for diagnostic and therapeutic purposes are also provided. | 07-31-2014 |
20140234330 | IL-17 RECEPTOR A IS REQUIRED FOR IL-17C BIOLOGY - The present invention relates to Interleukin-17 ligand and receptor family members and the discovery that IL-17 receptor A and IL-17 receptor E form a heteromeric receptor complex that is biologically active, and that IL-17C activity requires the IL-17RA-IL-17RE heteromeric receptor complex. Antagonists of the IL-17RA-IL-17RE heteromeric receptor complex are disclosed, as well as various methods of use. | 08-21-2014 |
20150017123 | IL-1 FAMILY VARIANTS - The present invention provides compositions and methods relating to IL-1Rrp2 requiring proteins. | 01-15-2015 |
Karla J. Towne, Highlands Ranch, CO US
Patent application number | Description | Published |
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20090254943 | TECHNIQUE FOR IDENTIFYING FAVORITE PROGRAM CHANNELS FOR RECEIVING ENTERTAINMENT PROGRAMMING CONTENT OVER A COMMUNICATIONS NETWORK - A favorites list of program channels which a cable TV user likely prefers is generated automatically from which the user may select a program channel to watch. Each program channel in the favorites list is identified based on a measure of the duration in which the program channel is continuously tuned to. In an embodiment, this measure varies nonlinearly with such a duration. The favorites list may further comprise sublists of program channels which may correspond to different periods of a day, week, etc. The favorites list may be generated from programs watched on multiple viewing devices. | 10-08-2009 |
Lloyd I. Towne, Bryan, OH US
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20100028174 | CHECK VALVE HAVING INTEGRALLY FORMED SEAT AND SEAL BODY - A valve assembly includes first and second conduits having respective first and second flanges in abutment with each other, a stopper in the second conduit, and a valve body secured between the first and second flanges. The valve body includes a body bore in communication between the first and second conduits. The body bore defines a circular opening in one end of the valve body. The valve body also includes a circumferential notch that substantially insulates the circular opening from distortion arising from securing the valve body. The stopper snuggly seats against the circular opening to prevent fluid flow from the second conduit to the first conduit, but unseats to permit fluid flow from the first conduit to the second conduit. An o-ring may surround a portion of the valve body and be energized as the valve body is secured. A lip may surround the circular opening to provide a seat for the stopper. | 02-04-2010 |
20100043895 | VALVE ASSEMBLY WITH LOW RESISTANCE PILOT SHIFTING - A valve arrangement for placing a supply of motive fluid in alternating communication with first and second motive fluid chambers. The valve arrangement includes a power valve including a supply chamber, a pilot chamber, and a shiftable member separating the supply chamber from the pilot chamber. The valve arrangement also includes a pilot valve actuable between an on condition in which the pilot valve generates a pilot signal that shifts the power valve, and an off condition in which the pilot valve does not generate the pilot signal. At least a portion of the pilot valve is exposed to motive fluid, and the portion of the pilot valve exposed to motive fluid includes surface areas giving rise to a net zero actuating force arising from pressure of the motive fluid. Because there is no biasing force on the pilot valve, the pilot valve is shifted between the on and off conditions without significant resistance. | 02-25-2010 |
Lloyd Irvin Towne, Bryan, OH US
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20100196168 | PUMP END OF STROKE SENSOR - A prime mover includes a shaft assembly that is supported for reciprocal movement between first and second ends of a stroke, and that includes first and second portions having a first material, and a third portion in between the first and second portions, having a second material, different from the first material. A single inductive proximity sensor makes a first indication when proximate the first material, and makes a second indication, when proximate the second material. A portion of the sensor is proximate the first portion when the shaft is at the first end of the stroke, the same portion of the same sensor is proximate the second portion when the shaft is at the second end of the stroke, and the same portion of the same sensor is proximate the third portion the entire time the shaft is in between the first and second ends of the stroke. | 08-05-2010 |
Penny Towne, Tucson, AZ US
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20080227143 | STABILIZED HEMATOXYLIN - A stabilized hematoxylin composition is disclosed that includes one or both of a host compound and an antioxidant. The disclosed composition exhibits sufficient stability to be utilized in an automated staining process without undue degradation prior to use of the composition to stain a biological sample. Methods of using and making the stabilized composition also are disclosed. | 09-18-2008 |
20120276584 | STABILIZED HEMATOXYLIN - A stabilized hematoxylin composition is disclosed that includes one or both of a host compound and an antioxidant. The disclosed composition exhibits sufficient stability to be utilized in an automated staining process without undue degradation prior to use of the composition to stain a biological sample. Methods of using and making the stabilized composition also are disclosed. | 11-01-2012 |
20150346206 | Method of Identifying Treatment Responsive Non-Small Cell Lung Cancer Using Anaplastic Lymphoma Kinase (ALK) as a Marker - Disclosed herein are methods for identifying a subject as having NSCLC that is predicted or is likely to respond to treatment with an ALK inhibitor, for example crizotinib. The methods include identifying a sample including NSCLC tumor cells as ALK-positive or ALK-negative using immunohistochemistry (IBC) and scoring methods disclosed herein. A subject is identified as having NSCLC likely to respond to treatment with an ALK inhibitor if the sample is identified as ALK-positive and is identified as having NSCLC not likely to respond to treatment with an ALK inhibitor if the sample is identified as ALK-negative. According to certain embodiments of the methods, subjects predicted to respond to an ALK inhibitor may then be treated with an ALK inhibitor such as crizotinib. | 12-03-2015 |
Raymond Towne, Westland, MI US
Patent application number | Description | Published |
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20120067317 | ANTI-COGGING APPARATUS AND METHODS FOR REDUCING COGGING OF ROTATING SHAFT - An anti-cogging apparatus improves rotation of a rotatable shaft about an axis. The shaft has a cyclical cogging torque acting thereon in a first direction. The anti-cogging apparatus includes a first anti-cogging member and a second anti-cogging member that rotate relative to each other in concert with rotation of the shaft, and the anti-cogging members interact to provide an anti-cogging torque to the shaft in a second direction to at least partially offset the cogging torque. | 03-22-2012 |
20140165775 | MECHANICAL-BASED ANTI-COGGING APPARATUSES AND SYSTEMS FOR APPLYING AN ANTI-COGGING TORQUE ON A ROTATING SHAFT - An apparatus that improves rotation of a shaft. The shaft has a cyclical cogging torque acting thereon in a first direction. A support member is adjacent the shaft. The shaft is operable to rotate relative to the support member. A first anti-cogging member is coupled to the support member. A second anti-cogging member is coupled to the shaft to rotate based on rotation of the shaft. A cam surface has a lobe that is included on one of the first and second anti-cogging members. An abutment member is coupled to the other of the first and second anti-cogging members. The abutment member is operable to abut against the cam surface to provide an anti-cogging torque to the shaft in a second direction that opposes the first direction to at least partially offset the cogging torque. The biasing member biases the abutment member toward the cam surface. | 06-19-2014 |
20140165952 | MAGNET-BASED ANTI-COGGING APPARATUSES AND SYSTEMS FOR APPLYING AN ANTI-COGGING TORQUE ON A ROTATING SHAFT - An anti-cogging apparatus includes a first support member, a second support member, a first set of magnets, and a second set of magnets. The first support member is configured to be connected to and rotate with a rotatable shaft. The second support member does not rotate and is configured not to move with the first support member. The first set of magnets is mounted on the first support member in an alternating polarity or a non-alternating polarity configuration. The second set of magnets is mounted on the second support member in an alternating polarity configuration or a non-alternating polarity configuration. The first set of magnets magnetically interacts with the second set of magnets to provide an anti-cogging torque on the rotatable shaft. | 06-19-2014 |
20140165953 | ANTI-COGGING APPARATUS AND METHODS FOR REDUCING COGGING OF ROTATING SHAFT - An apparatus improves rotation of a rotatable shaft. The rotatable shaft has a cyclical cogging torque acting thereon in a first direction. The apparatus includes a support member, first and second anti-cogging members, a cam surface and an abutment member. The support member is adjacent the rotatable shaft. The rotatable shaft is operable to rotate relative to the support member. The second anti-cogging member is coupled to the rotatable shaft for rotation with the rotatable shaft. The cam surface is included on one of the first anti-cogging member and the second anti-cogging member. The abutment member is coupled to the other one of the first anti-cogging member and the second anti-cogging member. The abutment member is operable to abut against the cam surface to provide an anti-cogging torque to the rotatable shaft in a second direction that opposes the first direction to at least partially offset the cogging torque. | 06-19-2014 |
Robert Lyne Towne, Chapel Hill, NC US
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20130253956 | CHARGEBACK INSURANCE - Embodiments of the invention are directed to a chargeback insurance program offered through a payment processing network. The payment processing network is capable of processing chargeback requests on behalf of an enrolled merchant or enrolled issuer without requiring additional chargeback-related processes to be conducted by the merchant or issue. Chargebacks are processed by the payment processing network based on enrollment settings in the chargeback insurance program. | 09-26-2013 |
Silas A. Towne, Richland, WA US
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20100015327 | METHODS AND COMPOSITIONS FOR PREPARING POROUS ELECTRODES - Methods and feedstock compositions for preparing porous electrodes as contained in lithium ion and lithium polymer batteries that comprise an electrolyte composition are described. The methods are characterized by depositing on a substrate a feedstock having a soluble pore former, precipitating at least a portion of the soluble pore former from the feedstock, and dissolving the solid pore former from the electrode using at least a portion or constituent of the electrolyte composition. The feedstock compositions are characterized by a pore former that forms a two-phase system with at least one constituent of the electrolyte composition. The feedstock does not contain materials that are not also substantially contained in the lithium ion battery. | 01-21-2010 |
20130186775 | Separation and/or Sequestration Apparatus and Methods - Apparatus for separating CO | 07-25-2013 |
Stephen A. Towne, Highland, MI US
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20080203754 | AUTOMOTIVE RIM INSTRUMENT PANEL SKIN WITH INTEGRATED WINDSHIELD CLOSEOUT - A windshield closeout system including an instrument panel having a reaction injection molded skin layer, and a closeout component including a resiliently biased closeout section extending from and integrally formed with the skin layer. The closeout section may be biased upwards in a predetermined direction for contiguous engagement with a windshield upon installation of the instrument panel relative to the windshield. | 08-28-2008 |
Timothy B. Towne, Lindenhurst, IL US
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20090203664 | (1S,5S)-3-(5,6-DICHLORO-3-PYRIDINYL)-3,6- DIAZABICYCLO[3.2.0]HEPTANE - The present invention discloses (1S,5S)-3-(5,6-dichloro-3-pyridinyl)-3,6-diazabicyclo[3.2.0]heptane, salts thereof, and its use to treat pain and other disorders associated with the nicotinic acetylcholine receptor. | 08-13-2009 |
William Towne, Yorba Linda, CA US
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20110154956 | Locking Crescent Wrench - A crescent ratchet wrench capable of locking and of free and indexed opening and closing of jaws is disclosed herein. The wrench operates by means of a multipurpose shaft. The shaft controls an adjustment screw to allow free movement of the wrench jaws, increment ratcheting of the movement, or locking of the wrench in place. | 06-30-2011 |