Tous

Guillermo Tous, East Windsor, NJ US

Patent application number	Description	Published
20100278852	ANTIBODIES AGAINST AND METHODS FOR PRODUCING VACCINES FOR RESPIRATORY SYNCYTIAL VIRUS - The present invention relates to novel respiratory syncytial virus (RSV) F peptides and compositions comprising them. The present invention also relates to methods of evaluating anti-RSV antibody binding to F peptides. The present invention also relates to antibodies that immunospecifically bind to an F peptide of the present invention. The invention further provides methods and protocols for the administration of F peptides and/or antibodies that immunospecifically bind to F peptides for the prevention, neutralization, treatment of RSV infection. Additionally, the methods of the invention may be useful for the treatment, prevention and the amelioration of symptoms associated with RSV infection.	11-04-2010
20100278929	ANTIBODY FORMULATIONS HAVING OPTIMIZED AGGREGATION AND FRAGMENTATION PROFILES - The present invention provides methods of optimizing the production and purification of antibody formulations that immunospecifically bind to antigens of interest and are suitable for parenteral administration to a subject, which formulations exhibit increased stability due to reduced degradation and aggregation of the antibody component on long term storage. Such methods provide formulations that offer multiple advantages over formulations produced by non-optimized methods including less stringent or more readily available transportation/storage conditions, and less frequent dosing or smaller dosage amounts in the therapeutic, prophylactic and diagnostic use of such formulations. The invention further provides methods of utilizing the formulations of the present invention.	11-04-2010

Guillermo I. Tous, East Windsor, NJ US

Patent application number	Description	Published
20090030187	MACROMOLECULES COMPRISING A THIOETHER CROSS-LINK - The present invention provides macromolecules comprising at least one thioether cross-link. A thioether cross-link comprising a single thioether bond between two residues of a macromolecule. The macromolecules of the invention can display enhanced stability, pharmaceutical properties and functional properties. In particular, the invention provides an isolated antibodies comprising at least one thioether cross-link that specifically bind to particular antigens. The present invention also provides a composition comprising a macromolecule substantially free of a denaturing reagent, wherein the macromolecule comprises at least one thioether cross-link. In addition, the present invention provides a method for producing the macromolecules and compositions of the invention.	01-29-2009

Jordi Lluis Tous, Tarragona ES

Patent application number	Description	Published
20090036681	PROCESS FOR THE RESOLUTION OF ZOPICLONE AND INTERMEDIATE COMPOUNDS - The present invention refers to a process for the resolution into one of its enantiomers of the racemate of compound of formula (I):	02-05-2009
20090137798	Process for the Preparation of Delmopinol and Derivatives Thereof - A process for the preparation of delmopinol (3-(4-propylheptyl)-4-morpholinethanol) or a derivative or a pharmaceutically acceptable salt, or a solvate thereof, including an hydrate, comprises reacting oxazolidin [2, 3-c] morpholine and a grignard reagent, and optionally converting the delmopinol (or derivative) free base into a pharmaceutically acceptable salt. The oxazolidin [2, 3-c] morpholine and the grignard reagent are useful as intermediates in the production process.	05-28-2009
20100222579	Process for the Preparation of Delmopinol and Derivatives Thereof - A process for the preparation of delmopinol (3-(4-propylheptyl)-4-morpholinethanol) or a derivative or a pharmaceutically acceptable salt, or a solvate thereof, including a hydrate, comprises reacting oxazolidin [2,3-c] morpholine and a Grignard reagent, and optionally converting the delmopinol (or derivative) free base into a pharmaceutically acceptable salt. The oxazolidin [2,3-c] morpholine and the Grignard reagent are useful as intermediates in the production process.	09-02-2010
20100274018	PROCESS FOR THE RESOLUTION OF ZOPICLONE AND INTERMEDIATE COMPOUNDS - The present invention refers to a process for the resolution into one of its enantiomers of the racemate of compound of formula (I):	10-28-2010
20110092751	Process for the Preparation of Delmopinol and Derivatives Thereof - A process for the preparation of delmopinol (	04-21-2011

Loic Tous, Leuven BE

Patent application number	Description	Published
20140332072	Photovoltaic Cell And Method Of Forming The Same - A photovoltaic (PV) cell comprises a base substrate comprising silicon and including an upper doped region. A coating layer is disposed on the upper doped region and has an outer surface. Fingers are disposed in the coating layer. Each finger has a lower portion in electrical contact with the upper doped region, and an upper portion extending outwardly through the outer surface. Each finger comprises a first metal. A busbar is spaced from the upper doped region, which is free of physical contact with the busbar. The busbar is in electrical contact with the upper portions of the fingers. The busbar comprises a second metal and a third metal different from the first and second metals. The third metal has a melting temperature of no greater than about 300° C. A method of forming the PV cell is also provided.	11-13-2014

Loic Tous, Mespaul FR

Patent application number	Description	Published
20140335646	Method for Forming Metal Silicide Layers - The present invention is related to a method for forming a metal silicide layer on a textured silicon substrate surface. The method includes providing a metal layer on a textured silicon substrate and performing a pulsed laser annealing step providing at least one UV laser pulse with a laser fluence in the range between	11-13-2014