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| 20100208237 | POLYMERIC SUBSTRATES FOR RAMAN SPECTROSCOPY - The present invention generally provides substrates for use in a variety of analytical and/or diagnostic applications as well as optical systems that employ them, in particular systems based on surface enhanced Raman spectroscopy (SERS). In one aspect, the invention provides polymeric substrates having conductive surfaces that exhibit micron-sized, and preferably submicron-sized, structures. In other aspects, methods for fabricating such substrates are disclosed, including a step of irradiating a mold surface with a plurality of short laser pulses to form micron-sized or submicron-sized structures and the mold surface and generating the polymeric substrate by replication from the mold surface. | 08-19-2010 |
| 20110267683 | SYSTEM AND METHOD FOR MONITORING IN-SITU PROCESSING OF SPECIMENS USING COHERENT ANTI-STOKES RAMAN SCATTERING (CARS) MICROSCOPY - System and method are disclosed for in-situ monitoring of a specimen while undergoing a defined process. The system includes a processing system adapted to perform the defined process on the specimen, and a coherent anti-Stokes Raman scattering (CARS) microscopy system adapted to in-situ monitor the specimen. In another aspect, the CARS microscopy system is adapted to in-situ monitor the specimen simultaneous with the defined process being performed on the specimen by the processing system. In still another aspect, the CARS microscopy system is adapted to perform a measurement of the specimen while the defined process being performed on the specimen is paused or temporarily halted. | 11-03-2011 |
| 20140160467 | SYSTEM AND METHOD FOR CHARACTERIZING MATERIAL SHRINKAGE USING COHERENT ANTI-STOKES RAMAN SCATTERING (CARS) MICROSCOPY - System and method are disclosed for measuring properties (e.g., shrinkage) of a photosensitive material (e.g., photoresist) while undergoing a defined photolithography process. The system includes a photolithography processing system adapted to perform a defined photolithography process of the photosensitive material, and a coherent anti-Stokes Raman scattering (CARS) microscopy system adapted to perform measurement of the properties of the photosensitive material. In another aspect, the CARS microscopy system is adapted to measure properties of the photosensitive material simultaneous with the defined photolithography process being performed on the photosensitive material by the photolithography processing system. In still another aspect, the CARS microscopy system is adapted to measure properties of the photosensitive material while the defined photolithography process on the photosensitive material is paused. Another system is adapted to perform similar measurements during the manufacturing of the photosensitive material. | 06-12-2014 |
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| 20080278744 | Print job aesthetics enhancements detection and modeling through combined user activity analysis and content matching - An automated method for processing a print job includes receiving a submitted print job, extracting features from the submitted print job for characterizing the print job, comparing the extracted features with a predictive model which is based on features extracted from prior print jobs and enhancement operations performed on the prior print jobs, and generating at least one proposed enhancement operation for the submitted print job based on the comparison. The proposed enhancement operations may be presented to an operator for verification or, if the enhancement operations are determined to have a threshold level of confidence, may be automatically applied to the print job. | 11-13-2008 |
| 20090310152 | PRINT MEDIATOR - A print mediator includes an interface module which serves as an interface for a document to be submitted for printing. The interface module communicates with an associated printing infrastructure for acquiring color rendering information for a print queue of the printing infrastructure. A reviewing application receives the acquired color rendering information and generates a visual representation of a document to be submitted for printing based thereon. Problems relating to color rendering by the printing infrastructure are detected and proposals for correction are presented to the submitter by the reviewing application. The user can review the proposals and accept or reject them as well as making annotations on the document. An analogous reviewing application is accessed by the print shop operator to review the document and submitter's annotations. | 12-17-2009 |
| 20110087675 | METHOD FOR VISUAL ASSET REPLACEMENT ACCOUNTING FOR COST, COPYRIGHT, AND CONFIDENTIALITY REQUIREMENTS - Systems and methods of replacing digital assets within a multimedia document are provided. The systems and methods include a user workstation that can receive a selection from a user for an original asset in the document to be replaced. Alternative assets can be retrieved that have a level of appropriateness with the selected original asset. Constraints on use of the alternative assets can be determined and a fitness value of each of the alternative assets can be calculated based on the appropriateness and the constraints on use. The alternative assets with the highest fitness values can be presented to the user for the user to select to replace the original asset. | 04-14-2011 |
| 20110184950 | SYSTEM FOR CREATIVE IMAGE NAVIGATION AND EXPLORATION - A system and method for assisting a user in navigation of an image dataset are disclosed. The method includes receiving a user's text query, retrieving images responsive to the query from an image dataset, providing for receiving the user's selection of a first feature selected from a set of available first features via a graphical user interface, providing for receiving the user's selection of a second feature selected from a set of available second features different from the first features via the graphical user interface, and displaying at least some of the retrieved images on the graphical user interface. The displayed images are arranged, e.g., grouped, according to levels and/or combinations of levels of the user-selected first and second features. | 07-28-2011 |
| 20120166472 | SYSTEM AND METHOD FOR COLLABORATIVE GRAPHICAL SEARCHING WITH TANGIBLE QUERY OBJECTS ON A MULTI-TOUCH TABLE - A system and a method are disclosed for developing a query. The system includes a display device for displaying elements, such as images, textures, color palettes, ad textual elements, which are selectable as query elements for forming a query. A physical space is provided on the display in which a physical object can be positioned. At least one physical object is positioned in the physical space, which is recognized by the system as having an identifier stored in memory to which a query can be linked. A sensor is provided for detecting a physical manipulation of the physical object in the physical space which represents absorbing a query element into a query. A query generator generates a query based on the absorbed query element. The query is thus associated in memory with the identifier for the recognized object. In this way, several physical objects can be manipulated on the display device, each one corresponding to a respective, single query. | 06-28-2012 |
| 20120254790 | DIRECT, FEATURE-BASED AND MULTI-TOUCH DYNAMIC SEARCH AND MANIPULATION OF IMAGE SETS - A system and method for manipulating graphic objects on a tactile user interface are provided. The graphic objects can be photographic images which are retrieved in response to a query and are clustered, based on values of first and second user-selected features assigned to the graphic objects. A navigation map is displayed on the user interface. The navigation map represents the clusters of graphic objects in first and second dimensions, corresponding to the first and second features. A user can manipulate a target window displayed on the navigation map using the tactile user interface. The target window encompasses a subset of the clustered graphic objects. A synchronized display of graphic objects in the subset of graphic objects on the user interface corresponds to the subset of clustered graphic objects within the displayed target window. | 10-04-2012 |
| 20130142322 | SYSTEM AND METHOD FOR ENHANCING CALL CENTER PERFORMANCE - A system and method for visualizing performance metrics are disclosed. The system includes a data acquisition component which collects information related to a set of agents operating in a work environment, a performance metric computation component which computes, for one of the agents, values for a performance metric at each of a plurality of times within a selected time period, and a representation generator which generates a representation for display to the agent, the representation providing the agent with information on the agent's current value for the performance metric. A processor implements the data acquisition component, the performance metric computation component, and the representation generator. | 06-06-2013 |
| 20140192970 | SYSTEM TO SUPPORT CONTEXTUALIZED DEFINITIONS OF COMPETITIONS IN CALL CENTERS - A system, method, and device for forming contextualized competitions in a work environment are disclosed. The system includes a performance metric computation component which computes performance metrics, a visualization component which generates a visual interface for display to a supervisor, and a processor which implements the components. The method includes receiving information related to a set of agents operating in a work environment. A first aggregated value for a first performance metric and a second aggregated value for a second performance metric are computed. The first and second values are visualized, and a predicted effect on the second performance metric when the first performance metric is altered is visualized. The device serves as a decision-making support tool including a plurality of control mechanisms for altering at least one performance metric and displaying the predicted effect on another. | 07-10-2014 |
| 20160086125 | IMPLICIT AND EXPLICIT COLLECTIVE DEFINITION OF LEVEL OF DIFFICULTY FOR METRICS BASED COMPETITIONS IN CALL CENTERS - Methods and systems for managing a metric-based competition in a work environment to increase productivity. Information related to a set of participants in a work environment can be received. One or more interfaces can be generated, which allow participants to input data for use in collaboratively defining key performance indicators associated with a proposed competition and based at least in part on the information related to the participants, so as to increase participant motivation by providing the participants with more agency and choice with respect to competitions in the work environment. | 03-24-2016 |
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| 20090137798 | Process for the Preparation of Delmopinol and Derivatives Thereof - A process for the preparation of delmopinol (3-(4-propylheptyl)-4-morpholinethanol) or a derivative or a pharmaceutically acceptable salt, or a solvate thereof, including an hydrate, comprises reacting oxazolidin [2, 3-c] morpholine and a grignard reagent, and optionally converting the delmopinol (or derivative) free base into a pharmaceutically acceptable salt. The oxazolidin [2, 3-c] morpholine and the grignard reagent are useful as intermediates in the production process. | 05-28-2009 |
| 20100222579 | Process for the Preparation of Delmopinol and Derivatives Thereof - A process for the preparation of delmopinol (3-(4-propylheptyl)-4-morpholinethanol) or a derivative or a pharmaceutically acceptable salt, or a solvate thereof, including a hydrate, comprises reacting oxazolidin [2,3-c] morpholine and a Grignard reagent, and optionally converting the delmopinol (or derivative) free base into a pharmaceutically acceptable salt. The oxazolidin [2,3-c] morpholine and the Grignard reagent are useful as intermediates in the production process. | 09-02-2010 |
| 20110092751 | Process for the Preparation of Delmopinol and Derivatives Thereof - A process for the preparation of delmopinol ( | 04-21-2011 |
| 20120149912 | PROCESS FOR THE PREPARATION OF 1-BENZYL-3-HYDROXYMETHYL-1H-INDAZOLE AND ITS DERIVATIVES AND REQUIRED MAGNESIUM INTERMEDIATES - The present invention relates to the process for the conversion of 1-benzyl-3-hydroxymethyl-1H-indazole according to formula (II), to the 1-benzyl-3-hydroxylmethyl-1H-indazole according to formula (I). | 06-14-2012 |
| 20120184752 | PROCESS FOR THE PREPARATION OF 1-BENZYL-3-HYDROXYMETHYL-1H-INDAZOLE AND ITS DERIVATIVES AND REQUIRED MAGNESIUM INTERMEDIATES - The present invention relates to the process for the preparation of 1-benzyl-3-hydroxymethyl-1H-indazole according ing to formula (II), to be used in a subsequent process for the preparation of 1-benzyl-3-hydroxymethyl-1H-indazole according to formula (I). | 07-19-2012 |
| 20130261160 | METHOD OF PREPARATION OF METAXALONE - The present invention relates to a method of preparation of metaxalone comprising reaction of triglycidyl isocyanurate (TGIC) with m-xylenol, characterized in that said reaction is carried out in a solvent mixture comprising an aprotic polar solvent with dielectric constant greater than or equal to 30 and at least one other solvent selected from the group comprising apolar solvents and aprotic polar solvents with dielectric constant below 30 said solvent mixture comprising from 5 to 40 wt. % of said first solvent and from 95 to 60 wt. % of said second solvent, adding the TGIC at a temperature between 30° C. and 50° C., and after adding the TGIC, raising the temperature of the reaction solution to a value between 80° C. and 180° C. in a time between 120 and 180 minutes at a rate of increase not greater that 1.25° C. per minute. The invention also relates to a metaxalone with a reduced content of impurities derived from incomplete reactions and/or side reactions of the method of production. | 10-03-2013 |
| 20150284345 | METHOD OF PREPARATION OF METAXALONE - The present invention relates to a method of preparation of metaxalone comprising reaction of triglycidyl isocyanurate (TGIC) with m-xylenol, characterized in that said reaction is carried out in a solvent mixture comprising an aprotic polar solvent with dielectric constant greater than or equal to 30 and at least one other solvent selected from the group comprising apolar solvents and aprotic polar solvents with dielectric constant below 30 said solvent mixture comprising from 5 to 40 wt. % of said first solvent and from 95 to 60 wt. % of said second solvent, adding the TGIC at a temperature between 30° C. and 50° C., and after adding the TGIC, raising the temperature of the reaction solution to a value between 80° C. and 180° C. in a time between 120 and 180 minutes at a rate of increase not greater that 1.25° C. per minute. The invention also relates to a metaxalone with a reduced content of impurities derived from incomplete reactions and/or side reactions of the method of production. | 10-08-2015 |
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| 20100056539 | TRAZODONE AND TRAZODONE HYDROCHLORIDE IN PURIFIED FORM - A process of production of trazodone or trazodone hydrochloride that comprises the steps of: (a) preparing an organic phase comprising trazodone in at least one organic solvent; (b) preparing an aqueous phase comprising at least one basic compound; (c) mixing said aqueous phase with said organic phase; (d) heating at a temperature of at least 40° C. for at least 30 minutes; (e) recovering said trazodone; and, optionally, (f) treating said trazodone with hydrochloric acid to obtain trazodone hydrochloride. Trazodone or trazodone hydrochloride comprising less than 15 ppm of alkylating substances, and a pharmaceutical composition comprising said trazodone hydrochloride. | 03-04-2010 |
| 20120142699 | TRAZODONE AND TRAZODONE HYDROCHLORIDE IN PURIFIED FORM - A process of production of trazodone or trazodone hydrochloride that comprises: (a) preparing an organic phase comprising trazodone in at least one organic solvent; (b) preparing an aqueous phase comprising at least one basic compound; (c) mixing said aqueous phase with said organic phase; (d) heating at a temperature of at least 40° C. for at least 30 minutes; (e) recovering said trazodone; and, optionally, (f) treating said trazodone with hydrochloric acid to obtain trazodone hydrochloride. Trazodone or trazodone hydrochloride comprising less than 15 ppm of alkylating substances, and a pharmaceutical composition comprising said trazodone hydrochloride. | 06-07-2012 |
| 20130012520 | TRAZODONE AND TRAZODONE HYDROCHLORIDE IN PURIFIED FORM - A process of production of trazodone or trazodone hydrochloride that comprises: (a) preparing an organic phase comprising trazodone in at least one organic solvent; (b) preparing an aqueous phase comprising at least one basic compound; (c) mixing said aqueous phase with said organic phase; (d) heating at a temperature of at least 40° C. for at least 30 minutes; (e) recovering said trazodone; and, optionally, (f) treating said trazodone with hydrochloric acid to obtain trazodone hydrochloride. Trazodone or trazodone hydrochloride comprising less than 15 ppm of alkylating substances, and a pharmaceutical composition comprising said trazodone hydrochloride. | 01-10-2013 |
| 20130203771 | TRAZODONE AND TRAZODONE HYDROCHLORIDE IN PURIFIED FORM - A process of production of trazodone or trazodone hydrochloride that comprises: (a) preparing an organic phase comprising trazodone in at least one organic solvent; (b) preparing an aqueous phase comprising at least one basic compound; (c) mixing said aqueous phase with said organic phase; (d) heating at a temperature of at least 40° C. for at least 30 minutes; (e) recovering said trazodone; and, optionally, (f) treating said trazodone with hydrochloric acid to obtain trazodone hydrochloride. Trazodone or trazodone hydrochloride comprising less than 15 ppm of alkylating substances, and a pharmaceutical composition comprising said trazodone hydrochloride. | 08-08-2013 |
| 20140057922 | TRAZODONE AND TRAZODONE HYDROCHLORIDE IN PURIFIED FORM - A process of production of trazodone or trazodone hydrochloride that comprises: (a) preparing an organic phase comprising trazodone in at least one organic solvent; (b) preparing an aqueous phase comprising at least one basic compound; (c) mixing said aqueous phase with said organic phase; (d) heating at a temperature of at least 40° C. for at least 30 minutes; (e) recovering said trazodone; and, optionally, (f) treating said trazodone with hydrochloric acid to obtain trazodone hydrochloride. Trazodone or trazodone hydrochloride comprising less than 15 ppm of allylating substances, and a pharmaceutical composition comprising said trazodone hydrochloride. | 02-27-2014 |
| 20140296250 | TRAZODONE AND TRAZODONE HYDROCHLORIDE IN PURIFIED FORM - A process of production of trazodone or trazodone hydrochloride that comprises: (a) preparing an organic phase comprising trazodone in at least one organic solvent; (b) preparing an aqueous phase comprising at least one basic compound; (c) mixing said aqueous phase with said organic phase; (d) heating at a temperature of at least 40° C. for at least 30 minutes; (e) recovering said trazodone; and, optionally, (f) treating said trazodone with hydrochloric acid to obtain trazodone hydrochloride. Trazodone or trazodone hydrochloride comprising less than 15 ppm of alkylating substances, and a pharmaceutical composition comprising said trazodone hydrochloride. | 10-02-2014 |
| 20150105402 | TRAZODONE AND TRAZODONE HYDROCHLORIDE IN PURIFIED FORM - A process of production of trazodone or trazodone hydrochloride that comprises: (a) preparing an organic phase comprising trazodone in at least one organic solvent; (b) preparing an aqueous phase comprising at least one basic compound; (c) mixing said aqueous phase with said organic phase; (d) heating at a temperature of at least 40° C. for at least 30 minutes; (e) recovering said trazodone; and, optionally, (f) treating said trazodone with hydrochloric acid to obtain trazodone hydrochloride. Trazodone or trazodone hydrochloride comprising less than 15 ppm of allylating substances, and a pharmaceutical composition comprising said trazodone hydrochloride. | 04-16-2015 |
| 20150297589 | TRAZODONE AND TRAZODONE HYDROCHLORIDE IN PURIFIED FORM - A process of production of trazodone or trazodone hydrochloride that comprises: (a) preparing an organic phase comprising trazodone in at least one organic solvent; (b) preparing an aqueous phase comprising at least one basic compound; (c) mixing said aqueous phase with said organic phase; (d) heating at a temperature of at least 40° C. for at least 30 minutes; (e) recovering said trazodone; and, optionally, (f) treating said trazodone with hydrochloric acid to obtain trazodone hydrochloride. Trazodone or trazodone hydrochloride comprising less than 15 ppm of alkylating substances, and a pharmaceutical composition comprising said trazodone hydrochloride. | 10-22-2015 |
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| 20090288272 | GRIP MEMBER WITH HAPTIC FEED-BACK - A grip member is equipped with a plurality of modules for generating haptic feed-back distributed along the grip member and activatable according to a pre-set sequence. | 11-26-2009 |
| 20100033002 | ERGONOMIC SUPPORT DEVICE FOR THE BODY OF THE OCCUPANT, FOR CHAIRS OR SEATS, PARTICULARLY FOR MOTOR-VEHICLE SEATS - A chair or a seat, in particular a seat for motor vehicles, includes an ergonomic device for supporting the body of the occupant, comprising a supporting panel having supporting laths, set at a distance from one another, which can be arched towards the body of the occupant, each independently of the others, by a respective actuator, which includes an actuator element constituted by a shape-memory material, which undergoes a reduction in length following upon heating above a predetermined transition temperature, higher than ambient temperature. Associated to the panel are electrical-supply means for supply of the shape-memory actuators and electronic control means for activating the laths independently and/or in succession according to any predetermined logic, in particular according to successive waves of activation, for example from above downwards, or from below upwards, or alternately from above and from below, so as to obtain a massaging effect. | 02-11-2010 |
| 20130341845 | MAGNETIC DEVICE FOR GRIPPING AND CLAMPING WORKPIECES - A magnetic device for gripping and clamping workpieces, in particular sheet-steel elements (L), comprises a supporting casing ( | 12-26-2013 |
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| 20140136174 | System and Method for Patient Specific Modeling of Liver Tumor Ablation - A method and system for tumor ablation planning and guidance based on a patient-specific model of liver tumor ablation is disclosed. A patient-specific anatomical model of the liver and circulatory system of the liver is estimated from 3D medical image data of a patient. Blood flow in the liver and the circulatory system of the liver is simulated based on the patient-specific anatomical model. Heat diffusion due to ablation is simulated based on a virtual ablation probe position and the simulated blood flow in the liver and the venous system of the liver. Cellular necrosis in the liver is simulated based on the simulated heat diffusion. A visualization of a simulated necrosis region is generated and displayed to the user for decision making and optimal therapy planning and guidance. | 05-15-2014 |
| 20140207715 | DATA DRIVEN REDUCTION OF MULTI-SCALE MODELS - A method of computing physiological measurements resulting from a multi-scale physiological system using a data-driven model includes generating a database of physiological measurements associated with a multi-scale physiological system. A computer uses dimensionality reduction techniques on the database to identify a reduced set of components explaining the multi-scale physiological system. The computer learns a data-driven model of the multi-scale physiological system from the database. Then, new input parameters are received by the computer and used to compute new physiological measurements using the data-driven model. New derived physiological indicators are computed by the computer based on the reduced set of components. Once computed, the new derived physiological indicators may be displayed along with the new physiological measurements. | 07-24-2014 |
| 20150042646 | System and Method for Patient Specific Planning and Guidance of Electrophysiology Interventions - A method and system for patient-specific planning and guidance of electrophysiological interventions is disclosed. A patient-specific anatomical heart model is generated from cardiac image data of a patient. A patient-specific cardiac electrophysiology model is generated based on the patient-specific anatomical heart model and patient-specific electrophysiology measurements. Virtual electrophysiological interventions are performed using the patient-specific cardiac electrophysiology model. A simulated electrocardiogram (ECG) signal is calculated in response to each virtual electrophysiological intervention. | 02-12-2015 |
| 20150045644 | System and Method for Estimating Artery Compliance and Resistance from 4D Cardiac Images and Pressure Measurements - A method and system for estimating arterial compliance and resistance based on medical image data and pressure measurements is disclosed. An arterial inflow estimate over a plurality of time points is determined based on medical image data of a patient. An arterial pressure measurement of the patient is received. At least one cardiac cycle of the arterial pressure measurement is synchronized with at least one cardiac cycle of the arterial inflow measurement. Arterial compliance and resistance of the patient is estimated based on the arterial inflow estimate and the synchronized arterial pressure measurement. | 02-12-2015 |
| 20150073765 | SYSTEM AND METHOD FOR PREDICTION OF RESPIRATORY MOTION FROM 3D THORACIC IMAGES - A method and system for prediction of respiratory motion from 3D thoracic images is disclosed. A patient-specific anatomical model of the respiratory system is generated from 3D thoracic images of a patient. The patient-specific anatomical model of the respiratory system is deformed using a biomechanical model. The biomechanical model is personalized for the patient by estimating a patient-specific thoracic pressure force field to drive the biomechanical model. Respiratory motion of the patient is predicted using the personalized biomechanical model driven by the patient-specific thoracic pressure force field. | 03-12-2015 |
| 20150242588 | System and Method for Personalized Computation of Tissue Ablation Extent Based on Medical Images - A method and system for personalized computation of tissue ablation extent based on medical images of a patient is disclosed. A patient-specific anatomical model of the liver and liver vessels is estimated from medical image data of a patient. Blood flow in the liver and liver vessels is simulated. An ablation simulation is performed that uses a bio-heat model to simulate heat diffusion due to an ablation based on the simulated blood flow and a cellular necrosis model to simulate cellular necrosis in the liver based on the simulated heat diffusion. Personalized tissue parameters of the bio-heat model and the cellular necrosis model are estimated based on observed results of a preliminary ablation procedure. Planning of the ablation procedure is then performed using the personalized bio-heat equation and the cellular necrosis model. The model can be subsequently refined as more ablation observations are obtained. | 08-27-2015 |
| 20150242589 | Method and System for Image-Based Estimation of Multi-Physics Parameters and Their Uncertainty for Patient-Specific Simulation of Organ Function - A method and system for estimating tissue parameters of a computational model of organ function and their uncertainty due to model assumptions, data noise and optimization limitations is disclosed. As applied to a cardiac use-case, a patient-specific anatomical heart model is generated from medical image data of a patient. A patient-specific computational heart model is generated based on the patient-specific anatomical heart model. Patient-specific parameters and corresponding uncertainty values are estimated for at least a subset of parameters of the patient-specific computational heart model. A surrogate model is estimated for a forward model of cardiac function, and the surrogate model is applied within Bayesian inference to estimate the posterior probability density function of the parameter space of the forward model. Cardiac function for the patient is simulated using the patient-specific computational heart model. The estimated parameters, their uncertainty, and the computed cardiac function are displayed to the user. | 08-27-2015 |
| 20150294082 | SYSTEM AND METHOD FOR PATIENT-SPECIFIC IMAGE-BASED GUIDANCE OF CARDIAC ARRHYTHMIA THERAPIES - A method and system for image-based patient-specific guidance of cardiac arrhythmia therapies is disclosed. A patient-specific anatomical heart model is generated from medical image data of a patient. A patient-specific cardiac electrophysiology model is generated based on the patient-specific anatomical heart model and electrophysiology measurements of the patient. One or more virtual electrophysiological interventions are performed using the patient-specific cardiac electrophysiology model. One or more pacing targets or ablation targets based on the one or more virtual electrophysiological interventions are displayed. | 10-15-2015 |
| 20150305706 | ESTIMATION OF A MECHANICAL PROPERTY OF ANATOMY FROM MEDICAL SCAN DATA - A mechanical property of anatomy is estimated from a patient in vivo, such as estimating a patient-specific material property of a valve. A morphological model is used to determine anatomy dynamics. A biomechanical model, using the anatomy dynamics, predicts the dynamics, based, at least in part, on one or more material properties. Using an inverse solution based on comparison of dynamics predicted by the biomechanical model and the dynamics determined from the morphological model, values for the material properties are determined. | 10-29-2015 |
| 20150347709 | METHOD AND SYSTEM FOR INTERACTIVE COMPUTATION OF CARDIAC ELECTROMECHANICS - A method and system for simulating cardiac function of a patient is disclosed. A patient-specific anatomical model of at least a portion of the patient's heart is generated from medical image data of the patient. Cardiac electrophysiology potentials are calculated over a computational domain defined by the patient-specific anatomical model for each of a plurality of time steps using a patient-specific cardiac electrophysiology model. The electrophysiology potentials acting on a plurality of nodes of the computational domain are calculated in parallel for each time step. Biomechanical forces over the computational domain for each of the plurality of time steps using a cardiac biomechanical model coupled to the cardiac electrophysiology model. The biomechanical forces acting on a plurality of nodes of the mesh domain are estimated in parallel for each time step. Blood flow and cardiac movement are computed at each of the plurality of time steps based on the calculated biomechanical forces. Computed electrophysiology potentials, biomechanical forces and cardiac parameters are displayed, user input is interactively received to change at least one of the parameters of the patient-specific models, and the electrophysiology potentials, the biomechanical forces, and the blood flow and cardiac movement are recalculated. | 12-03-2015 |
| 20150366532 | VALVE REGURGITANT DETECTION FOR ECHOCARDIOGRAPHY - A regurgitant orifice of a valve is detected. The valve is detected from ultrasound data. An anatomical model of the valve is fit to the ultrasound data. This anatomical model may be used in various ways to assist in valvular assessment. The model may define anatomical locations about which data is sampled for quantification. The model may assist in detection of the regurgitant orifice using both B-mode and color Doppler flow data with visualization without the jet. Segmentation of a regurgitant jet for the orifice may be constrained by the model. Dynamic information may be determined based on the modeling of the valve over time. | 12-24-2015 |
| 20150371437 | System and Method for Visualization of Cardiac Changes Under Various Pacing Conditions - A system and method for visualization of cardiac changes under various pacing conditions for intervention planning and guidance is disclosed. A patient-specific anatomical heart model is generated based on medical image data of a patient. A patient-specific computational model of heart function is generated based on patient-specific anatomical heart model. A virtual intervention is performed at each of a plurality of positions on the patient-specific anatomical heart model using the patient-specific computational model of heart function to calculate one or more cardiac parameters resulting from the virtual intervention performed at each of the plurality of positions. One or more outcome maps are generated visualizing, at each of the plurality of positions on the patient-specific anatomical heart model, optimal values for the one or more cardiac parameters resulting from the virtual intervention performed at the that position on the patient-specific anatomical heart model. | 12-24-2015 |
| 20160022369 | System And Method For Interactive Patient Specific Simulation Of Radiofrequency Ablation Therapy - A method and system for interactive patient-specific simulation of liver tumor ablation is disclosed. A patient-specific anatomical model of the liver and circulatory system of the liver is estimated from 3D medical image data of a patient. A computational domain is generated from the patient-specific anatomical model of the liver. Blood flow in the liver and the circulatory system of the liver is simulated based on the patient-specific anatomical model. Heat diffusion due to ablation is simulated based on a virtual ablation probe position and the simulated blood flow in the liver and the circulatory system of the liver by solving a bio-heat equation for each node on the level-set representation using a Lattice-Boltzmann method (LBM) implementation. Cellular necrosis in the liver is computed based on the simulated heat diffusion. Visualizations of a computed necrosis region and temperature maps of the liver are generated. A user input is interactively received to modify the position of the virtual ablation probe, the heat diffusion and cellular necrosis is re-simulated based on the user input, and the visualizations of the computed necrosis region and the temperature maps are updated. | 01-28-2016 |
| 20160058520 | System and Method for Patient-Specific Image-Based Simulation of Artial Electrophysiology - A method and system for simulating patient-specific atrial electrophysiology is disclosed. A patient-specific anatomical atria model is generated from medical image data of a patient. A patient-specific atria electrophysiology model is generated based on the patient-specific anatomical atria model and electrophysiology measurements of the patient. One or more virtual electrophysiological therapies are performed by performing atrial electrophysiology simulations using the patient-specific atria electrophysiology model. Atrial electrophysiology simulation results resulting from the one or more virtual electrophysiological therapies are displayed. | 03-03-2016 |
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| 20120022843 | Method and System for Comprehensive Patient-Specific Modeling of the Heart - A method and system for patient-specific modeling of the whole heart anatomy, dynamics, hemodynamics, and fluid structure interaction from 4D medical image data is disclosed. The anatomy and dynamics of the heart are determined by estimating patient-specific parameters of a physiological model of the heart from the 4D medical image data for a patient. The patient-specific anatomy and dynamics are used as input to a 3D Navier-Stokes solver that derives realistic hemodynamics, constrained by the local anatomy, along the entire heart cycle. Fluid structure interactions are determined iteratively over the heart cycle by simulating the blood flow at a given time step and calculating the deformation of the heart structure based on the simulated blood flow, such that the deformation of the heart structure is used in the simulation of the blood flow at the next time step. The comprehensive patient-specific model of the heart representing anatomy, dynamics, hemodynamics, and fluid structure interaction can be used for non-invasive assessment and diagnosis of the heart, as well as virtual therapy planning and cardiovascular disease management. Parameters of the comprehensive patient-specific model are changed or perturbed to simulate various conditions or treatment options, and then the patient specific model is recalculated to predict the effect of the conditions or treatment options. | 01-26-2012 |
| 20120203530 | Method and System for Patient-Specific Computational Modeling and Simulation for Coupled Hemodynamic Analysis of Cerebral Vessels - A method and system for patient-specific computational modeling and simulation for coupled hemodynamic analysis of cerebral vessels is disclosed. An anatomical model of a cerebral vessel is extracted from 3D medical image data. The anatomical model of the cerebral vessel includes an inner wall and an outer wall of the cerebral vessel. Blood flow in the cerebral vessel and deformation of the cerebral vessel wall are simulated using coupled computational fluid dynamics (CFD) and computational solid mechanics (CSM) simulations based on the anatomical model of the cerebral vessel. | 08-09-2012 |
| 20120230568 | Method and System for Model-Based Fusion of Multi-Modal Volumetric Images - A method and system for fusion of multi-modal volumetric images is disclosed. A first image acquired using a first imaging modality is received. A second image acquired using a second imaging modality is received. A model and of a target anatomical structure and a transformation are jointly estimated from the first and second images. The model represents a model of the target anatomical structure in the first image and the transformation projects a model of the target anatomical structure in the second image to the model in the first image. The first and second images can be fused based on estimated transformation. | 09-13-2012 |
| 20120232386 | VALVE TREATMENT SIMULATION FROM MEDICAL DIAGNOSTIC IMAGING DATA - Valve treatment simulation is performed from patient specific imaging data for therapy planning. A model of the valve may be generated from the patient specific data automatically or with very minimal user indication of anatomy locations relative to an image. Any characteristics for the valve not extracted from images of the patient may be added to create a volumetric model. Added characteristics include chordae, such as chordae length and leaflet fiber direction. The characteristics may be adjusted based on user feedback and/or comparison with images of the patient. The effect of therapy on closure of the valve may be simulated from the model. For instance, mitral clip intervention is simulated on the patient-specific model. Valves are deformed according to the clip location. Valve closure is then simulated to predict effect of the therapy in terms of mitral regurgitation. | 09-13-2012 |
| 20120232853 | PHYSICALLY-CONSTRAINED MODELING OF A HEART IN MEDICAL IMAGING - Physically-constrained modeling of a heart is provided. Patient-specific data may be used to estimate heart anatomy locations. A model is applied to the data for estimation. For increased accuracy of estimation, the biomechanics of the heart, such as the valve, may be used to constrain the estimation. By applying a dynamic system between estimated anatomy locations of different times, the locations may be deformed or refined. The modeled heart and/or valve may be used to estimate hemodynamics. The resulting velocities or other motion information may be used to emulate ultrasound Doppler imaging for comparing with acquired ultrasound Doppler data. The comparison may validate the modeling. | 09-13-2012 |
| 20130197881 | Method and System for Patient Specific Planning of Cardiac Therapies on Preoperative Clinical Data and Medical Images - A method and system for patient-specific planning of cardiac therapy, such as cardiac resynchronization therapy (CRT), based on preoperative clinical data and medical images, such as ECG data, magnetic resonance imaging (MRI) data, and ultrasound data, is disclosed. A patient-specific anatomical model of the left and right ventricles is generated from medical image data of a patient. A patient-specific computational heart model, which comprises cardiac electrophysiology, biomechanics and hemodynamics, is generated based on the patient-specific anatomical model of the left and right ventricles and clinical data. Simulations of cardiac therapies, such as CRT at one or more anatomical locations are performed using the patient-specific computational heart model. Changes in clinical cardiac parameters are then computed from the patient-specific model, constituting predictors of therapy outcome useful for therapy planning and optimization. | 08-01-2013 |
| 20130197884 | Method and System for Advanced Measurements Computation and Therapy Planning from Medical Data and Images Using a Multi-Physics Fluid-Solid Heart Model - Method and system for computation of advanced heart measurements from medical images and data; and therapy planning using a patient-specific multi-physics fluid-solid heart model is disclosed. A patient-specific anatomical model of the left and right ventricles is generated from medical image patient data. A patient-specific computational heart model is generated based on the patient-specific anatomical model of the left and right ventricles and patient-specific clinical data. The computational model includes biomechanics, electrophysiology and hemodynamics. To generate the patient-specific computational heart model, initial patient-specific parameters of an electrophysiology model, initial patient-specific parameters of a biomechanics model, and initial patient-specific computational fluid dynamics (CFD) boundary conditions are marginally estimated. A coupled fluid-structure interaction (FSI) simulation is performed using the initial patient-specific parameters, and the initial patient-specific parameters are refined based on the coupled FSI simulation. The estimated model parameters then constitute new advanced measurements that can be used for decision making. | 08-01-2013 |
| 20130226542 | Method and System for Fast Patient-Specific Cardiac Electrophysiology Simulations for Therapy Planning and Guidance - A method and system for patient-specific cardiac electrophysiology is disclosed. Particularly, a patient-specific anatomical model of a heart is generated from medical image data of a patient, a level-set representation of the patient-specific anatomical model is generated of the heart on a Cartesian grid; and a transmembrane action potential at each node of the level-set representation of the of the patient-specific anatomical model of the heart is computed on a Cartesian grid. | 08-29-2013 |
| 20130324841 | System and Method for Real-Time Ultrasound Guided Prostate Needle Biopsy Based on Biomechanical Model of the Prostate from Magnetic Resonance Imaging Data - A method and system for real-time ultrasound guided prostate needle biopsy based on a biomechanical model of the prostate from 3D planning image data, such as magnetic resonance imaging (MRI) data, is disclosed. The prostate is segmented in the 3D ultrasound image. A reference patient-specific biomechanical model of the prostate extracted from planning image data is fused to a boundary of the segmented prostate in the 3D ultrasound image, resulting in a fused 3D biomechanical prostate model. In response to movement of an ultrasound probe to a new location, a current 2D ultrasound image is received. The fused 3D biomechanical prostate model is deformed based on the current 2D ultrasound image to match a current deformation of the prostate due to the movement of the ultrasound probe to the new location. | 12-05-2013 |
| 20140012558 | SYSTEM AND METHODS FOR INTEGRATED AND PREDICTIVE ANALYSIS OF MOLECULAR, IMAGING, AND CLINICAL DATA FOR PATIENT-SPECIFIC MANAGEMENT OF DISEASES - A system operating in a plurality of modes to provide an integrated analysis of molecular data, imaging data, and clinical data associated with a patient includes a multi-scale model, a molecular model, and a linking component. The multi-scale model is configured to generate one or more estimated multi-scale parameters based on the clinical data and the imaging data when the system operates in a first mode, and generate a model of organ functionality based on one or more inferred multi-scale parameters when the system operates in a second mode. The molecular model is configured to generate one or more first molecular findings based on a molecular network analysis of the molecular data, wherein the molecular model is constrained by the estimated parameters when the system operates in the first mode. The linking component, which is operably coupled to the multi-scale model and the molecular model, is configured to transfer the estimated multi-scale parameters from the multi-scale model to the molecular model when the system operates in the first mode, and generate, using a machine learning process, the inferred multi-scale parameters based on the molecular findings when the system operates in the second mode. | 01-09-2014 |
| 20140022250 | System and Method for Patient Specific Planning and Guidance of Ablative Procedures for Cardiac Arrhythmias - A method and system for patient-specific planning and guidance of an ablation procedure for cardiac arrhythmia is disclosed. A patient-specific anatomical heart model is generated based on pre-operative cardiac image data. The patient-specific anatomical heart model is registered to a coordinate system of intra-operative images acquired during the ablation procedure. One or more ablation site guidance maps are generated based on the registered patient-specific anatomical heart model and intra-operative patient-specific measurements acquired during the ablation procedure. The ablation site guidance maps may include myocardium diffusion and action potential duration maps. The ablation site guidance maps are generated using a computational model of cardiac electrophysiology which is personalized by fitting parameters of the cardiac electrophysiology model using the intra-operative patient-specific measurements. The ablation site guidance maps are displayed by a display device during the ablation procedure. | 01-23-2014 |
| 20140296842 | Patient Specific Planning and Simulation of Ablative Procedures - Patient specific temperature distribution in organs, due to an ablative device, is simulated. The effects of ablation are modeled. The modeling is patient specific. The vessel structure for a given patient, segmented from medical images, is accounted for as a heat sink in the model of biological heat transfer. A temperature map is generated to show the effects of ablation in a pre-operative analysis. Temperature maps resulting from different ablation currents and ablation device positions may be used to determine a more optimal location of the ablative device for a given patient. Other models may be included, such as accounting for the tissue damage during the ablation. | 10-02-2014 |
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| 20100276050 | Heavy Load Vehicle Tire - A tire includes: a carcass structure including at least one carcass ply, a belt structure, a tread band radially superimposed on the belt structure; two sidewalls; the belt structure including: at least one pair of lateral reinforcing layers incorporating reinforcing elements oriented in a substantially circumferential direction; a first belt layer radially superimposed on the pair of lateral reinforcing layers, provided with reinforcing elements inclined with respect to the equatorial plane of the tire; a second belt layer radially superimposed on the first belt layer, provided with reinforcing elements inclined with respect to the equatorial plane in a direction opposite to those of the first belt layer; an external belt layer applied in a radially external position with respect to the first and the second belt layers. Preferably, the tire is a super single wide base heavy load vehicle tire. The tire is particularly useful for heavy load vehicles such as, for example, trucks, trailers, or buses. | 11-04-2010 |
| 20130263988 | TYRE FOR HEAVY LOAD VEHICLE WHEELS - A tyre includes a tread provided with blocks formed among substantially longitudinal and transverse grooves, wherein among the blocks particularly broad intersections are formed, for example, by staggering substantially transverse grooves of circumferential rows axially in side-by-side relationship, of blocks with rounded corners, and wherein, inside such broad intersections, a stocky-shaped protrusion is arranged which has a lateral stiffness greater than the lateral stiffness of the surrounding blocks. | 10-10-2013 |
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| 20090322353 | READOUT-INTERFACE CIRCUIT FOR A CAPACITIVE MICROELECTROMECHANICAL SENSOR, AND CORRESPONDING SENSOR - In a capacitive sensor, a detection structure, of a microelectromechanical type, is provided with a fixed element and a mobile element, capacitively coupled to one another, generating a capacitive variation as a function of a quantity to be detected, and with a parasitic coupling element, capacitively coupled to at least one between the mobile element and the fixed element generating a first parasitic capacitance, intrinsic to the detection structure; a readout-interface circuit is connected to the detection structure and generates, on an output terminal thereof, an output signal as a function of the capacitive variation. The readout-interface circuit has a feedback path between the output terminal and the parasitic coupling element so as to drive the first intrinsic parasitic capacitance with the output signal. | 12-31-2009 |
| 20130031950 | MICROELECTROMECHANICAL GYROSCOPE WITH SELF-CALIBRATION FUNCTION AND METHOD OF CALIBRATING A MICROELECTROMECHANICAL GYROSCOPE - A microelectromechanical gyroscope having a supporting structure; a mass capacitively coupled to the supporting structure and movable with a first degree of freedom and a second degree of freedom, in response to rotations of the supporting structure about an axis; driving components, for keeping the mass in oscillation according to the first degree of freedom; a read interface for detecting transduction signals indicating the capacitive coupling between the mass and the supporting structure; and capacitive compensation modules for modifying the capacitive coupling between the mass and the supporting structure. Calibration components detect systematic errors from the transduction signals and modify the capacitive compensation modules as a function of the transduction signals so as to attenuate the systematic errors. | 02-07-2013 |
| 20130033274 | MICROELECTROMECHANICAL SENSOR WITH DIFFERENTIATED PERFORMANCES AND METHOD OF CONTROLLING A MICROELECTROMECHANICAL SENSOR - A microelectromechanical sensor includes a supporting structure and a sensing mass, which is elastically coupled to the supporting structure, is movable with respect thereto with one degree of freedom in response to movements according to an axis and is coupled to the supporting structure through a capacitive coupling. A sensing device senses, on terminals of the capacitive coupling, transduction signals indicative of displacements of the first sensing mass according to the degree of freedom. The sensing device includes at least one first reading chain, having first operative parameters, one second reading chain, having second operative parameters different from the first operative parameters, and one selective electrical connection structure that couples the first reading chain and the second reading chain to the first terminals. | 02-07-2013 |
| 20130127454 | MAGNETIC FIELD SENSOR INCLUDING AN ANISOTROPIC MAGNETORESISTIVE MAGNETIC SENSOR AND A HALL MAGNETIC SENSOR - A magnetic field sensor, including a Hall magnetic sensor, formed within a first die and configured to detect a first magnetic field, and a first anisotropic magnetoresistive magnetic sensor, having a first anisotropic magnetoresistive transducer, formed within a second die and configured to generate an electrical measurement quantity as a function of a second magnetic field. An electronic reading circuit formed within the first die, is electrically connected to the first anisotropic magnetoresistive transducer, and provides a first measure indicating the second magnetic field, on the basis of the electrical measurement quantity. The first and second dice are fixed with respect to one another and have main surfaces parallel to the same reference plane. The first magnetic field being oriented in a first direction perpendicular to the reference plane and the second magnetic field being oriented in a second direction parallel to the reference plane. | 05-23-2013 |
| 20140077823 | HIGH SIGNAL TO NOISE RATIO CAPACITIVE SENSING ANALOG FRONT-END - Capacitance sensing circuits and methods are provided. The capacitance sensing circuit includes a capacitance-to-voltage converter configured to receive a signal from a capacitance to be sensed and to provide an output signal representative of the capacitance, an output chopper configured to convert the output signal of the capacitance-to-voltage converter to a sensed voltage representative of the capacitance to be sensed, an analog accumulator configured to accumulate sensed voltages during an accumulation period of NA sensing cycles and to provide an accumulated analog value, an amplifier configured to amplify the accumulated analog value, and an analog-to-digital converter configured to convert the amplified accumulated analog value to a digital value representative of the capacitance to be sensed. The analog accumulator may include a low pass filter having a frequency response to filter wideband noise. | 03-20-2014 |
| 20140078096 | CONFIGURABLE ANALOG FRONT-END FOR MUTUAL CAPACITANCE SENSING AND SELF CAPACITANCE SENSING - Capacitance sensing circuits and methods are provided. A dual mode capacitance sensing circuit includes a capacitance-to-voltage converter having an amplifier and an integration capacitance coupled between an output and an inverting input of the amplifier, and a dual mode switching circuit responsive to mutual mode control signals for a controlling signal supplied from a capacitive touch matrix to the capacitance-to-voltage converter in a mutual capacitance sensing mode and responsive to self mode control signals for controlling signals supplied from the capacitive touch matrix to the capacitance-to-voltage converter in a self capacitance sensing mode, wherein the capacitance sensing circuit is configurable for operation in the mutual capacitance sensing mode or the self capacitance sensing mode. | 03-20-2014 |
| 20140312919 | CONFIGURABLE ANALOG FRONT-END FOR MUTUAL CAPACITANCE SENSING AND SELF CAPACITANCE SENSING - Capacitance sensing circuits and methods are provided. A dual mode capacitance sensing circuit includes a capacitance-to-voltage converter having an amplifier and an integration capacitance coupled between an output and an inverting input of the amplifier, and a switching circuit responsive to mutual mode control signals for a controlling signal supplied from a capacitive touch matrix to the capacitive to voltage converter in a mutual capacitance sensing mode and responsive to self mode control signals for controlling signals supplied from the capacitive touch matrix to the capacitance-to-voltage converter in a self capacitance sensing mode, wherein the capacitance sensing circuit is configurable for operation in the mutual capacitance sensing mode or the self capacitance sensing mode. | 10-23-2014 |
| 20150145801 | HIGH SIGNAL TO NOISE RATIO CAPACITIVE SENSING ANALOG FRONT-END - Capacitance sensing circuits and methods are provided. The capacitance sensing circuit includes a capacitance-to-voltage converter configured to receive a signal from a capacitance to be sensed and to provide an output signal representative of the capacitance, an output chopper configured to convert the output signal of the capacitance-to-voltage converter to a sensed voltage representative of the capacitance to be sensed, an analog accumulator configured to accumulate sensed voltages during an accumulation period of NA sensing cycles and to provide an accumulated analog value, an amplifier configured to amplify the accumulated analog value, and an analog-to-digital converter configured to convert the amplified accumulated analog value to a digital value representative of the capacitance to be sensed. The analog accumulator may include a low pass filter having a frequency response to filter wideband noise. | 05-28-2015 |
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| 20120109355 | SUBSTRATE PROCESSING SYSTEM - Embodiments of the present invention provide an apparatus and method for processing substrates in a processing system that has an increased system throughput, improved system uptime, and improved device yield performance, while maintaining a repeatable and accurate substrate processing. The system may include multiple processing nests laterally positionable by use of a planar motor via multiple planar movers controlled by a system controller. A substrate supported by each processing nest may be angularly positionable by a rotary actuator. The system may be used in screen printing, ink jet printing, thermal processing, device testing, and material removal processes, among others. | 05-03-2012 |
| 20130102103 | METHODS AND APPARATUS FOR THE CLOSED-LOOP FEEDBACK CONTROL OF THE PRINTING OF A MULTILAYER PATTERN - Embodiments of the present invention provide apparatus and methods for closed-loop control utilized in printing a multilayer pattern on a substrate. In one embodiment, a solar cell formation process is provided. The process comprises positioning a substrate on a substrate receiving surface of a printing station, printing a first patterned layer on a region of the substrate, acquiring a first optical image of the first patterned layer and storing the first optical image in a buffer, printing a second patterned layer over the region of the substrate, wherein the second patterned layer is aligned over the region of the substrate using information received from the acquired first optical image. | 04-25-2013 |
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| 20090305441 | NEXT GENERATION SCREEN PRINTING SYSTEM - Embodiments of the present invention provide an apparatus and method for processing substrates using a multiple screen printing chamber processing system that has an increased system throughput, improved system uptime, and improved device yield performance, while maintaining a repeatable and accurate screen printing process on the processed substrates. In one embodiment, the multiple screen printing chamber processing system is adapted to perform a screen printing process within a portion of a crystalline silicon solar cell production line in which a substrate is patterned with a desired material, and then processed in one or more subsequent processing chambers. | 12-10-2009 |
| 20120216691 | BLADE FOR SILK-SCREEN PRINTING ON A PRINT SUPPORT - An apparatus for screen printing a surface of a substrate includes a screen printing net, a print extremity element, and a supporting structure supporting the print extremity element. The supporting structure includes a slider coupled to the print extremity element and adapted to guide the movement of the print extremity element in a first direction, a support frame having a housing that is associated with a portion of the slider so as to allow movement of the slider relative to the support frame, and an actuation member coupled to the slider. The print extremity element urges a print material through the screen printing net onto the surface of the substrate. The actuation member positions the print extremity element relative to the screen printing net in the first direction, and includes magnets disposed within the housing of the support frame, and an electric coil disposed proximate to the magnets. | 08-30-2012 |
| 20120216694 | Method For Centering A Print Track - A method for depositing a material on a surface of a substrate includes depositing a first print material and a second print material on the surface of the substrate using a printing apparatus, and depositing a marker element on a portion of the substrate surface. The deposited first print material forms a plurality of first print tracks in a pattern and the deposited second print material forms one or more second print tracks on the surface of the substrate. In addition, the second print tracks includes a centering feature, where there is no second print material within the centering feature and at least a portion of the centering feature is disposed on the portion of the surface of the substrate having the marker element. Further, at least a portion of the second print tracks cover at least a portion of the plurality of first print tracks. | 08-30-2012 |
| 20120219725 | Substrate Processing Apparatus And Method - An apparatus for processing a substrate includes an inspection system disposed in a first position to detect the location and orientation of the substrate supported on a supporting surface of a processing nest positioned in the first position and one or more processing heads disposed in the second and third positions and configured to perform a first and a second process on the substrate when the processing nest is moved to the second and third positions by an actuator assembly. A method for processing a substrate includes detecting the location and orientation of the substrate disposed on the processing nest which is positioned in the first position and aligning one or more processing heads to the substrate when the processing nest is positioned in the second and third positions and under the processing heads using data detected by an inspection system positioned in the first position. | 08-30-2012 |
| 20120223046 | PRINTING METHOD FOR PRINTING ELECTRONIC DEVICES AND RELATIVE CONTROL APPARATUS - Embodiments of the invention may provide a method of printing one or more print tracks on a print support, or substrate, comprising two or more printing steps in each of which a layer of material is deposited on the print support according to a predetermined print profile. In each printing step, subsequent to the first step, each layer of material is deposited at least partially on top of the layer of material printed in the preceding printing step, so that each layer of printed material has an identical or different print profile with respect to at least a layer of material underneath. The method may further comprise depositing material in each printing step that is equivalent to or different from the material deposited in at least one of other the print layers. | 09-06-2012 |
| 20120225188 | Multiple Control Method for Printing a Multilayer Pattern and Relative Plant - A method for multi-layer printing on a support, comprising a first printing step performed in a printing station in a system, one or more subsequent printing steps that are performed in one or more subsequent printing stations in the system and a plurality of alignment steps performed in the system, wherein the alignment steps are used to effect the correct positioning of a material printed in a subsequent printing step. The method comprises, downstream of each printing step and upstream of each alignment step, a control step in which detection devices detect the position of a layer printed on a support and/or the position of the support in the system by use of a control unit that compares at least one of the positions detected with predefined positions and/or with the positions detected in the previous control step, and wherein the results of the comparison are used in the alignment step. | 09-06-2012 |
| 20120225518 | Method and Apparatus to Detect the Alignment of a Substrate - A method of detecting the alignment of a substrate during a sequence of printing steps, comprises detecting in a detection unit a position of at least one printing track that forms a printed pattern onto a surface of the substrate in a first printing station, determining a reference point in at least a portion of the printing track, comparing the actual position of the reference point with an expected or previously detected position of the reference point, determining an offset between the actual position and the expected or previously detected position of the reference point, adjusting the reciprocal position between the printing head of a second printing station and the substrate to account for the determined offset, and then printing a second pattern over the first pattern. | 09-06-2012 |
| 20120315825 | DEVICE FOR HOUSING A SUBSTRATE, AND RELATIVE METHOD - A device for supporting a substrate is provided. The device includes a base body having two or more layers of an insulating material, a substrate support surface formed by the upper layer of the insulating material, one or more cavities formed in a thickness of the base body, and one or more metal elements disposed in the one or more cavities. The substrate support surface of the base body supports the substrate thereon in a processing nest of a printing apparatus. In addition, each metal element comprises one or more features that are used to couple the base body to the processing nest. The metal elements are also provided for magnetically or electromagnetically positioning the base body on a magnetic work plane of a grinding tool. A method is also provided to make the device and attach the device to a planar surface of a processing nest. | 12-13-2012 |
| 20130052334 | METHOD AND APPARATUS FOR PRINTING A MULTILAYER PATTERN - The present invention provides a control method and apparatus for printing a multilayer pattern on a substrate. In one embodiment, a method for printing a multilayer pattern includes a first printing operation comprising depositing a first patterned layer on a region of a surface of the substrate, a second printing operation comprising depositing a second patterned layer over the region of the surface or first patterned layer, and verifying the precision of the alignment of the second patterned layer relative to the first patterned layer. Verifying comprises acquiring a first optical image of the first patterned layer after the first printing operation, acquiring a second optical image of the second patterned layer after the second printing operation, and determining the position of the second patterned layer by performing an image subtraction process to form a first subtracted optical image and comparing the subtracted optical image with the first image. | 02-28-2013 |
