Thomas Braun
Thomas Braun, Bad Nauheim DE
Patent application number | Description | Published |
---|---|---|
20100178280 | USE OF SIRT7 FOR TREATING AGE-RELATED DISEASES - The present invention relates to a pharmaceutical composition comprising (i) a nucleic acid molecule encoding a protein having Sirt7 function wherein said nucleic acid molecule (a) has the sequence of SEQ ID NO: 1, 3, 5 or 7; (b) encodes a protein having the sequence of SEQ ID NO: 2, 4, 6 or 8; (c) hybridizes under stringent conditions to the molecule of (a) or (b); or (d) has an identity on the nucleic acid level of at least 80% with the molecule of (a), (b) or (c); (ii) a vector comprising the nucleic acid molecule of (i); (iii) a host cell comprising the vector of (ii); or (iv) a protein encoded by the nucleic acid molecule of (i). The pharmaceutical composition is used for example in the treatment of age-related diseases. Furthermore, the invention relates to screening methods for the identification of compounds useful in the treatment of age-related diseases. | 07-15-2010 |
20120121579 | TREATMENT OF ONCOSTATIN M RECEPTOR BETA MEDIATED HEART FAILURE - The present invention relates to an inhibitor of the oncostatin M receptor β or an inhibitor of an activator of the oncostatin M receptor β for use in the treatment and/or prevention of heart failure. The present invention also relates to a method of treating and/or preventing heart failure comprising administering a pharmaceutically effective amount of an inhibitor of the oncostatin M receptor β or an inhibitor of an activator of the oncostatin M receptor β to a subject in need thereof. Further, the present invention also relates to methods of identifying a compound suitable as a lead compound and/or as a medicament for the treatment and/or prevention of heart failure. | 05-17-2012 |
20120190580 | TREATMENT OF PATIENTS AFTER STENT IMPLANTATION OR BALLOON DILATATION AND DRUG ELUTING STENTS - The present invention relates to a nucleic acid molecule for use in the treatment or preventive treatment of a patient after stent implantation or balloon dilatation, wherein the nucleic acid molecule is selected from (a) a single-stranded nucleic acid molecule comprising or consisting of the sequence of SEQ ID NO: 1, 2, 3 or 4 or a sequence having at least 90% sequence identity to the sequence of SEQ ID NO: 1, 2, 3 or 4; (b) a hairpin RNA, wherein one of the regions forming the double-stranded portion of said hairpin RNA comprises or consists of the sequence of SEQ ID NO: 1, 2, 3 or 4 or a sequence having at least 90% sequence identity to the sequence of SEQ ID NO: 1, 2, 3 or 4; (c) an at least partially double-stranded RNA comprising two separate single strands, wherein a region within one of the strands, said region being located within the double-stranded portion of said double-stranded RNA, comprises or consists of the sequence of SEQ ID NO: 1, 2, 3 or 4 or a sequence having at least 90% sequence identity to the sequence of SEQ ID NO: 1, 2, 3 or 4; (d) a nucleic acid molecule encoding the nucleic acid molecule of (a) or the RNA (b); and (e) a nucleic acid molecule or a two nucleic acid molecules encoding the two separate single strands of the RNA of (c). The present invention also relates to a drug eluting stent comprising the nucleic acid molecule according to the invention. | 07-26-2012 |
Thomas Braun, Muenchen DE
Patent application number | Description | Published |
---|---|---|
20100046387 | DEVICE AND METHOD FOR DETERMINING A TRANSMISSION BEHAVIOR OF SUB-CHANNELS - A device for a method for determining the transmission performance of sub-channels of a transmission channel in a radio-communication system is specified, where data-comprising signal carriers are generated for the setup of the transmission channel within the radio-communication system and accommodated in the sub-channels of the transmission channel, and the transmission performance of the sub-channels is determined on the basis of the signal sub-carriers superposed with interferers. In this context, each sub-channel occupies a separate bandwidth sub-range of a total bandwidth range of the transmission channel. The bandwidth sub-range is disposed within the bandwidth at a spacing distance from other bandwidth sub-ranges of the total bandwidth range, and the interferers are limited to the bandwidth sub-range allocated to the respective sub-channel. | 02-25-2010 |
Thomas Braun, Ettringen DE
Patent application number | Description | Published |
---|---|---|
20090140831 | Coil for Producing a Magnetic Field - The invention relates to a coil for producing a magnetic field having at least one winding ( | 06-04-2009 |
20090272734 | Induction Heater - An induction heater for heating metallic billets with a yoke of E-shaped cross-section, on the middle limb of which a superconducting coil is seated, has a well located between the middle limb and each one of the respective two outer limbs. A billet can be heated by being rotated in each one of the two wells. | 11-05-2009 |
Thomas Braun, Munchen DE
Patent application number | Description | Published |
---|---|---|
20080214183 | Method of Determining an Error Rate and a Suitable Testing Device - The invention relates to a method and to a test device ( | 09-04-2008 |
Thomas Braun, Tauberbischofsheim DE
Patent application number | Description | Published |
---|---|---|
20110221255 | ITEM OF SEATING FURNITURE - An item of seating furniture contains a seat providing a seat surface, a generally circular foot panel positioning the item of seating furniture on a floor, and a central part, which connects the seat to the foot panel and of which a vertical center axis runs centrally through the foot panel. The foot panel is of at least partially convex configuration and that side of the foot panel which is directed toward the floor is configured, at least in part, as a non-slip surface. This creates an ergonomic item of seating furniture which stands in a stable state. | 09-15-2011 |
Thomas Braun, Girlan/eppan (bz) IT
Patent application number | Description | Published |
---|---|---|
20110252514 | Apple tree named Golden Parsi - The present invention relates to a variety of an apple tree obtained by branch mutation and by selection of the variety ‘Golden Clone B’. The present invention variety ‘Golden Parsi’ exhibits an appropriate distinguishability, homogeneity, uniformity, and stability. The vigor of the tree is medium. The tree type is ramified. The habit of the apple tree is spreading. The pubescence on an upper half of a shoot is weak or similar to the pubescence in ‘Golden Delicious’. The thickness as measured by the diameter at the center is medium or similar to the thickness in ‘Jonagold’ for a one year old shoot. The number of lenticels is many for a one year old shoot. The predominant color of a flower is dark pink in a balloon stage. An overcolor appears early in season with a brown-red color. The overcolor disappears almost totally, and toward harvest increases and gets red. The overcolor remains red even after months of storage. | 10-13-2011 |
Thomas Braun, Nieder Erlenbach DE
Patent application number | Description | Published |
---|---|---|
20120181156 | GAS-INSULATED HIGH-VOLTAGE SWITCHING SYSTEM - A gas-insulated high-voltage switching includes a housing having a switch module including an actuator, a control module, a cable outlet, a transformer, a circuit breaker, and a grounding switch. The circuit breaker and the grounding switch are spatially and structurally separated from one another and may be operated by a common actuator. | 07-19-2012 |
Thomas Braun, Biberach DE
Patent application number | Description | Published |
---|---|---|
20120291814 | Process and System for Cleaning and Maintaining and for Operating a Medical Hand-held Instrument - A process and also to a system for cleaning and maintaining a medical hand-held instrument, in particular a dental hand-held instrument, with an elongate grip sleeve in which elements are arranged which pertain to a drive arrangement and which are, in particular, rotatably supported, for example a shaft. For the purpose of cleaning and maintaining the hand-held instrument different media are conducted through it. In this connection a first medium, for example oil, is conducted merely through a power-transmission region surrounding the elements of the drive arrangement, whereas, on the other hand, a second medium, for example a cleaning agent, is conducted additionally also through at least one further cavity within the hand-held instrument. | 11-22-2012 |
Thomas Braun, Stuttgart DE
Patent application number | Description | Published |
---|---|---|
20130076383 | METHOD FOR TESTING AN INTEGRATED CIRCUIT - A method for testing an integrated circuit and an integrated circuit. The integrated circuit has an internal testing structure which may be accessed via an internal test access port and a control bus which is conducted to the outside via control ports, it being possible to switch over between a running mode and a test mode so that, in the test mode, the test access port is accessed via the control ports and the control bus, thus testing the integrated circuit. | 03-28-2013 |
Thomas Braun, Glen Head, NY US
Patent application number | Description | Published |
---|---|---|
20140062280 | BOTTOM MOUNT ADJUSTABLE CABINET MOUNTED FRAME - An extendable and retractable container assembly for recyclable materials which includes a pair of drawer slide structures that are interconnected by a rear cross-member bracket and a front cross-member bracket to retain them in spaced parallel relation with the rear ends of the slide structures being independently adjustably supported by two unique adjusting structures. | 03-06-2014 |
Thomas Braun, Hof DE
Patent application number | Description | Published |
---|---|---|
20140336591 | Dosing System - The invention concerns a dosing system for adjusting a dose volume of a fluid medium. The dosing system has a longitudinal center axis ( | 11-13-2014 |
20150032061 | Medical Injection Device - A medical injection device has a syringe. The syringe has a container for the medium to be injected and an injection cannula, which communicates with the container. A needle guard of the injection device can be moved between an injection position and a safe position. In the injection position, the injection cannula can be uncovered in order to inject the medium. In the safe position, a cannula tip of the injection cannula is recessed in a protective component of the needle guard. A securing device securely fixes the protective component in the safe position. The result is an injection device having a needle guard that can be manipulated intuitively and operated safely. | 01-29-2015 |
20150032062 | Medical Injection Device - A medical injection device has an injection unit and an anti-rotation device. Said anti-rotation device is non-rotationally connected to a port and connection portion of the injection device so as to surround the outside thereof in the manner of a sleeve. As a result, an intuitively usable and operationally safe injection device is obtained. When a protective cap for an injection cannula of the injection unit is being removed from the port and connection portion, an unwanted rotation of the port and connection portion relative to the container about components of a plug-in connection arranged therebetween is safely prevented. | 01-29-2015 |
20150119810 | Dosage System - The invention relates to a dosage system for setting a dosage volume of a flowable medium. The dosage system comprises a longitudinal axis, a dosage container for receiving the medium, and a dosage piston body which is adapted for sealed displacement in the dosage container between an initial position and a dosage position. In the initial position, the dosage piston body is fully inserted in the dosage container while in the dosage position, the dosage piston body has been pulled out of the dosage container along a path corresponding to the desired dosage amount of the medium. The dosage system further exhibits a draw-up limiting member for limiting a draw-up path of the dosage piston body in the dosage position, the draw-up limiting member being axially securable to the dosage container in one of several limiting positions relative to the longitudinal axis. The dosage system further exhibits a stop for abutment against the draw-up limiting member in order to limit the draw-up path of the dosage piston body in the dosage position. The stop is rigidly axially connected with the dosage piston body in the axial direction. | 04-30-2015 |
Thomas Braun, Girlan IT
Patent application number | Description | Published |
---|---|---|
20140366231 | Gala schnico red - Borkh ‘Gala Schnico red’ variety is distinguished by a unique combination of characteristics including an intensive red overcolor covering 100% of the fruit skin and a 30% higher number of lenticels per unit area on the fruit skin. | 12-11-2014 |
Thomas Braun, Mineola, NY US
Patent application number | Description | Published |
---|---|---|
20150008813 | TOP MOUNT ADJUSTABLE CABINET MOUNTED FRAME - A container assembly for recyclable materials mounted within a cabinet for movement between an extended position in which the open tops of the bins or containers are exposed for receiving recyclable materials and a retracted position in which the bins are concealed. The container assembly is supported for movement between its extended and retracted positions by a pair of drawer slide assemblies with supporting cross-member brackets being connected to the slide assemblies. The slide assemblies are mounted adjacent to a top of the cabinet. The slide assemblies interengage with brackets on which a door can be mounted for adjustment to accurately fit the opening in the front wall to form a closure for the cabinet in which the container assembly is mounted. | 01-08-2015 |
Thomas Braun, Grossostheim DE
Patent application number | Description | Published |
---|---|---|
20160082620 | EXTRUSION HEAD HAVING A PERFORATED PLATE OF A GRANULATING SYSTEM - An extrusion head having a perforated plate of a granulating system. The extrusion head can have a head part and a perforated plate with a perforated-plate wear insert, a perforated-plate main body, a central inflow cone, an inflow cone part, a plurality of nozzle channels, a plurality of perforated dies, and at least one corrosion protected fastener. The perforated-plate can be detachably fastened to the head part. The head part can have at least one central melt channel into which the inflow cone part projects and distributes a melt flow among nozzle channels which can be arranged in the shape of a ring and among the perforated dies which can be arranged in at least one ring. The at least one fastener can be positioned in a central region of the at least one ring of the perforated dies. | 03-24-2016 |
Thomas Braun, Wuppertal DE
Patent application number | Description | Published |
---|---|---|
20160120367 | Kitchen appliance comprising POSITIONING DEVICE - The invention relates to a kitchen appliance, in particular a mixer, comprising a housing ( | 05-05-2016 |
Thomas Braun, Heusweiler DE
Patent application number | Description | Published |
---|---|---|
20160138266 | GLAZING - Glazings comprising first and second channel-section glazing elements are described. The first and second channel-section glazing elements are arranged to define a cavity in which is located an inner glazing element comprising a glass glazing element, in particular a soda-lime-silica glass sheet, channel-section glazing element or sheet of rolled glass having at least one fire polished edge. The inner glazing element divides the cavity into at least two spaces to improve the thermal and/or noise performance of the glazing. By using low emissivity coatings on one or more major surfaces of one or more of the glazing elements, the thermal performance may be further improved. Mechanical performance may be modified by the particular type of inner glazing element used. It is possible to retrofit existing glazings to improve the thermal and/or noise performance thereof. | 05-19-2016 |