Patent application number | Description | Published |
20080206258 | Novel Tetrahydropyridothiophenes - Compounds of a certain formula (I) | 08-28-2008 |
20080260749 | Novel Tetrahydropyridothiophenes - Compounds of a certain formula (I) | 10-23-2008 |
20090098133 | Tetrahydropyridothiophenes as Antiproliferative Agents for the Treatment of Cancer - Compounds of a certain formula (I), | 04-16-2009 |
20090117074 | Sulfonylpyrroles as Histone Deacetylase Inhibitors - The invention relates to compounds of formula (I) | 05-07-2009 |
20090156604 | FUSED BICYCLIC IMIDAZOLES - Compounds of formula (I) | 06-18-2009 |
20090246169 | INDOLOPYRIDINES AS EG5 KINESIN MODULATORS - Compounds of a certain formula I, in which R1, R2, R3, R4, R5 and R6 have the meanings indicated in the description, are effective compounds with anti-proliferative and/or apoptosis inducing activity. | 10-01-2009 |
20090252706 | Tetrahydropyridothiophenes As Antripoliferative Agents For The Treatment Of Cancer - The invention relates to compounds of formula (I) wherein Ra is —C(O)ORI, in which R1 is 1-7C-alkyl. 3-7C-cycloakyl, 1-7C-alkyl substituted by Raa, or 2-7C-alkyl substituted by Rab and Rac on different carbon atoms, Rb is -T-Q, in which T is 1-6C-alkylene or 3-7C-cycloalkylene, and Q is substituted by Rba and Rbb and Rbc, and is phenyl, which are useful for the therapy of hyperproliferative diseases, in particular human cancer. | 10-08-2009 |
20090257977 | NOVEL TETRAHYDROPYRIDOTHIOPHENES - Compounds of a certain formula (I), in which Ra and Rb have the meanings indicated in the description, are novel effective compounds with anti-proliferative and apoptosis inducing activity. | 10-15-2009 |
20090258873 | Novel tetrahydropyridothiophenes - Compounds of a certain formula (I), in which Ra and Rb have the meanings indicated in the description, are novel effective compounds with anti-proliferative and apoptosis inducing activity. | 10-15-2009 |
20090263353 | Novel Sulphonylpyrroles as Inhibitors of Hdac S Novel Sulphonylpyrroles - Compounds of a certain formula I, | 10-22-2009 |
20090297473 | Sulphonylpyrrole Hydrochloride Salts as Histone Deacetylases Inhibitors - Compounds of a certain formula 1, | 12-03-2009 |
20100074862 | N-SULPHONYLPYRROLES AND THEIR USE AS HISTONE DEACETYLASE INHIBITORS - Compounds of a certain formula (I), in which R1, R2, R3, R4, R5, R6 and R7 have the meanings indicated in the description, are novel effective HDAC inhibitors. | 03-25-2010 |
20100104659 | BENZOPYRANOPYRAZOLES - Compounds of a certain formula I, in which Ra, Rb and Rc have the meanings indicated in the description, are effective compounds with anti-proliferative and/or apoptosis inducing activity. | 04-29-2010 |
20100285149 | NOVEL TETRAHYDROPYRIDOTHIOPHENES - Compounds of a certain formula I, in which Ra and Rb have the meanings indicated in the description, are novel effective compounds with anti-proliferative and apoptosis inducing activity. | 11-11-2010 |
20100324038 | TETRAHYDROPYRIDOTHIOPHENES FOR THE TREATMENT OF PROLIFERATIVE DISEASES SUCH AS CANCER - The invention relates to compounds of formula I, wherein Ra is —C(O)OR1, in which R1 is 1-7C-alkyl, 3-7C-cycloalkyl, or 1-7C-alkyl substituted by one to four substituents independently selected from R2, Rb is -T-Q, in which T is 1-6C-alkylene or 3-7C-cycloalkylene, and either Q is optionally substituted by Rba and/or Rbb and/or Rbc, and is phenyl or naphthyl, or Q is optionally substituted by Rca and/or Rcb, and is Har, or Q is optionally substituted by Rda and/or Rdb, and is Het, or Q is optionally substituted by Rea and/or Reb, and is 3-7C-cycloalkyl, which are useful for the therapy of hyperproliferative diseases, in particular human cancer. | 12-23-2010 |
20110065734 | NOVEL BIFUNCTIONAL COMPOUNDS WHICH INHIBIT PROTEIN KINASES AND HISTONE DEACETYLASES - The present invention relates to a bifunctional compound of formula I or its pharmaceutically acceptable salts or solvates A-L-B (I) wherein A is a histone deacetylase (HDAC) inhibitory moiety, L is a single bond or a linker group and B is a protein kinase inhibitory moiety. The bifunctional compound according to formula (I) is useful for the treatment of malignant and non-malignant neoplasia and diseases related to abnormal cell growth. | 03-17-2011 |
20130310362 | FUSED PYRIMIDINES - The present invention relates to compounds of formula (I), | 11-21-2013 |
20130317002 | FUSED PYRIMIDINES - Compounds of formula (I) | 11-28-2013 |
20140088110 | FUSED BICYCLIC IMIDAZOLES - Compounds of formula (I) | 03-27-2014 |