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Tetsuo Nagano, Tokyo JP

Tetsuo Nagano, Tokyo JP

Patent application numberDescriptionPublished
20080249321Fluorescent Probes - A fluorescent probe which is represented by the following formula (wherein R10-09-2008
20080261314FLUORESCENT PROBE FOR ZINC - A compound represented by the following general formula (I) or a salt thereof:10-23-2008
20080281104Membrane-Anchoring Fluorescent Probe - A membrane anchoring-type fluorescent probe consisting of a compound comprising a phospholipid residue, a fluorescent probe compound residue, and a linker which binds the residues (e.g., the compound represented by the following formula).11-13-2008
20090118471NOVEL COUMARIN DERIVATIVES - A compound represented by the following general formula (I) or a salt thereof [R05-07-2009
20090258434FLUORESCENT PROBE FOR PEROXYNITRITE - A compound represented by the following general formula (I):10-15-2009
20090263910METHOD FOR MEASURING HYPOCHLORITE ION - A method for measuring hypochlorite ion, which comprises the steps of:10-22-2009
20090317914FLUORESCENT PROBE - A compound represented by the following general formula (I):12-24-2009
20090318707NOVEL MALEIMIDE DERIVATIVE - A compound represented by the following general formula (I):12-24-2009
20100029010Diaminorhodamine Derivative - A compound represented by the following formula (I) or (II):02-04-2010
20100068733pH-Sensitive Fluorescent Probe - A compound represented by the following general formula (I):03-18-2010
20100120160Fluorescent Probe - A compound represented by the formula (I) wherein R05-13-2010
20100285515FLUORESCENT PROBE - A compound represented by the following general formula (I):11-11-2010
20100297681FLUORESCENT PROBE FOR MEASUREMENT OF GLUCURONATE TRANSFERASE - A fluorescent probe for measurement of UDP-glucuronosyltransferase, which comprises a fluorescein derivative, wherein in the fluorescein derivative, the 2-carboxy group on the benzene ring of fluorescein is replaced with another monovalent substituent, provided that said substituent is a substituent other than sulfo group, and the substituent does not have carboxy group or sulfo group, and wherein the fluorescein derivative may have an arbitrary substituent at a position on the benzene ring other than the 2-position, and the fluorescein derivative may have a substituent selected from the group consisting of an alkoxy group and a halogen atom at the 2-position and/or the 7-position of fluorescein.11-25-2010
20100330685DIAMINORHODAMINE DERIVATIVE - A compound represented by the following formula (I) or (II):12-30-2010
20110033944METHOD FOR MEASURING HYPOCHLORITE ION - A method for measuring hypochlorite ion, which comprises the steps of:02-10-2011
20110038803FLUORESCENT PROBE - A fluorescent probe which specifically and efficiently traps nitrogen monoxide, zinc ion etc. to emit fluorescence is provided.02-17-2011
20110098475FLUORESCENT PROBES - A fluorescent probe which is represented by the following formula (wherein R04-28-2011
20110111515REAGENT FOR MEASUREMENT OF REACTIVE OXYGEN - A reagent for measurement of reactive oxygen, which can be used with a light of the near infrared region showing superior biological tissue permeability, wherein (i) a first cyanine compound residue and a second cyanine compound residue are bound to each other, (ii) the first cyanine compound residue has a property that it easily reacts with a reactive oxygen species and is thereby decomposed, and (iii) the second cyanine compound residue either equals or surpasses the first cyanine compound residue in its stability to the reactive oxygen species, and the first cyanine compound residue acts as a quenching group for the second cyanine compound residue.05-12-2011
20110117666FLUORESCENT PROBE - A fluorescent probe comprising a compound represented as (Fluorophore A)-S-(Fluorophore B) (Fluorophore A and Fluorophore B are fluorophores which emit fluorescence when they are irradiated with an excitation light of a wavelength of 600 to 950 nm, Fluorophore A has a property that it shows change of fluorescence characteristic before and after a specific reaction with an substance to be measured, and S represents a spacer which connects Fluorophore A and Fluorophore B), which compound shows substantial change in efficiency of fluorescence resonance energy transfer between Fluorophore A and Fluorophore B before and after the specific reaction with the objective substance, wherein Fluorophore A is represented by the following formula (AI):05-19-2011
20110159603FLUORESCENT PROBE SPECIFIC TO HYDROGEN PEROXIDE - A compound represented by the following general formula (IA) or (IB) (R06-30-2011
20110165085TUMOR SELECTIVE FLUORESCENT STAINING AGENT - A tumor cell or tumor tissue-selective fluorescent staining agent comprising a compound represented by the following general formula (I):07-07-2011
20110251404REAGENT FOR MEASUREMENT OF ACTIVE OXYGEN - A compound represented by the formula (I) (R10-13-2011
20110287552REAGENT FOR MEASURING ACTIVE NITROGEN - A compound represented by the general formula (I) [R11-24-2011
20120065384FLUORESCENT MRI PROBE - A fluorescent gadolinium complex compound comprising a residue of gadolinium.1,4,7,10-tetraazacyclododecane-N,N′,N″,N′″-tetraacetic acid or a residue of gadolinium.diethylenetriaminepentaacetic acid bound covalently with a group represented by the following general formula (I) (R03-15-2012
20120178174FLUORESCENT PROBE - A compound represented by the formula (I) wherein R07-12-2012
20130023675DIAGNOSTIC FOR CANCER - An agent for diagnosing cancer comprising, as an active ingredient, a compound represented by the following formula (I) (R01-24-2013
20130102776ANTICANCER AGENT - An anticancer agent comprising a compound represented by the formula (I) [R04-25-2013
20130289256FLUORESCENT PROBE - A compound represented by the formula (I) (R10-31-2013
20140057312FLUORESCENT PROBE - A compound represented by the formula (I) (one of substituents represented by R02-27-2014
20140248654ACIDIC ENVIRONMENT-DETECTING FLUORESCENT PROBE - Provided is a compound represented by formula (I), which can be used as a fluorescent probe that becomes highly fluorescent only in an intracellular acidic environment and can be adapted to the fluorescent imaging of an intracellular vesicle that is a microstructure.09-04-2014
20140342384FLUORESCENT PROBE - A compound represented by the formula (I) (R11-20-2014

Patent applications by Tetsuo Nagano, Tokyo JP

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