Patent application number | Description | Published |
20090325148 | Bead Array Reader Based-Hemagglutination and Hemagglutination Inhibition Assay - Hemagglutination assays and hemagglutination inhibition assays were introduced in medical and virology practice more than 60 years ago. Since then, these assays have become important tools for measuring concentrations and strengths of viral cultures, the efficacy of the anti-viral immunization, and for studying the neutralizing capacity of virus-specific antibodies. The present invention comprises an improved hemagglutination inhibition assay (HAI), with at least about a 10-fold increase in sensitivity versus the traditional the HAI, to provide more accurate measurements of components in, for example, fluids from the in vitro MIMICĀ® system when assessing the effects of anti-viral vaccines (e.g., for seasonal influenza). | 12-31-2009 |
20100120020 | FLUORESCENT NEUTRALIZATION AND ADHERENCE INHIBITION ASSAYS - The present invention comprises rugged, inexpensive, reliable, and sensitive laboratory assays of antibody-based viral neutralization activity and antibody-based viral adherence inhibition activity. The assays use inactivated, fluorescently-labeled virus, allowing the tests to be performed without extensive safety precautions. The interaction of the labeled virus with target cells is monitored using flow cytometric methods. A preferred embodiment uses simple and inexpensive flow cytometry methodologies and equipment, such as bead array readers used as simplified flow cytometers. The assays are rapid, taking no longer than a few hours and are readily conducted by a trained technician. The assays are sensitive because they use labeled viruses at low concentrations and determine neutralizing and blocking capacity of sera and antibody at low concentrations. The methods are appropriate for high-throughput screening of large panels of samples. | 05-13-2010 |
20110097705 | Surface-assisted hemagglutination and hemagglutination inhibition assays - Hemagglutination (HA) and hemagglutination inhibition (HAI) functional assays remain important instruments of analysis of virus-cell interaction and protecting efficacy of virus-specific antibodies and sera. However, they demonstrate limited sensitivity towards many viruses, and require significant volumes of viruses, erythrocytes, sera, and antibodies. The present invention comprises new and significantly more sensitive versions of the HA and HAI assays based on observing agglutination on activated surfaces of specifically opsonized plates and ELISA plates rather than in solution. A version of the new assay that uses ELISA plates additionally allows characterizing the affinity of functional antibodies in the tested sera and fluids, which is not possible in the classical HAI assay. The methods of the present invention can also be used to improve the sensitivity of agglutination methods based on latex beads and to develop agglutination methods using target cells other than erythrocytes. | 04-28-2011 |
Patent application number | Description | Published |
20090000626 | HAPTIC GUIDANCE SYSTEM AND METHOD - A method for joint replacement is provided. A representation of a first bone is created, and a representation of a second bone is created. Bone preparation for implanting a first implant on the first bone is planned. The first bone to receive the first implant is prepared by manipulating a surgical tool to sculpt the first bone. Bone preparation for implanting a second implant on the second bone after preparing the first bone is planned. The second bone to receive the second implant is prepared by manipulating the surgical tool to sculpt the second bone. | 01-01-2009 |
20090000627 | HAPTIC GUIDANCE SYSTEM AND METHOD - A surgical planning method is provided. A representation of a bone of a joint is created. The joint is moved to a first position. A first point corresponding to a first location in the joint is identified when the joint is in the first position. The joint is moved to a second position. A second point corresponding to a second location in the joint is identified, when the joint is in the second position. Bone preparation for implanting an implant on the bone is planned based at least in part on the first and second points. | 01-01-2009 |
20090012531 | HAPTIC GUIDANCE SYSTEM AND METHOD - A surgical apparatus includes a surgical device, configured to be manipulated by a user to perform a procedure on a patient, and a computer system. The computer system is programmed to create a representation of an anatomy of a patient; to associate the anatomy and a surgical device with the representation of the anatomy; to manipulate the surgical device to perform a procedure on a patient by moving a portion of the surgical device in a region of the anatomy; to control the surgical device to provide at least one of haptic guidance and a limit on manipulation of the surgical device, based on a relationship between the representation of the anatomy and at least one of a position, an orientation, a velocity, and an acceleration of a portion of the surgical device; and to adjust the representation of the anatomy in response to movement of the anatomy during the procedure. | 01-08-2009 |
20090012532 | HAPTIC GUIDANCE SYSTEM AND METHOD - A surgical planning method is provided. A height of a cartilage surface above a bone is detected. A representation of the bone and a representation of the height of the cartilage surface is created. Bone preparation for implanting an implant on the bone is planned based at least in part on the detected height of the cartilage surface. | 01-08-2009 |
20120109150 | HAPTIC GUIDANCE SYSTEM AND METHOD - A surgical apparatus includes a surgical device, configured to be manipulated by a user to perform a procedure on a patient, and a computer system. The computer system is programmed to implement control parameters for controlling the surgical device to provide at least one of haptic guidance to the user and a limit on user manipulation of the surgical device, based on a relationship between an anatomy of the patient and at least one of a position, an orientation, a velocity, and an acceleration of a portion of the surgical device, and to adjust the control parameters in response to movement of the anatomy during the procedure. | 05-03-2012 |
Patent application number | Description | Published |
20140267615 | WEARABLE CAMERA - An image capture system includes a camera including a processor, an imager coupled to a lens mounted on a substantially curved camera body, said curved camera body anatomically shaped for mounting to a forehead region; and a headband to secure the camera to the forehead to capture a picture or video. | 09-18-2014 |
20140267742 | CAMERA WITH REMOTE WATCH - Systems and processes for communicating a surfing experience includes capturing preview pictures or videos using a camera mounted on a surfer's head or a surfboard; displaying the preview pictures or videos on a remote watch; adjusting the camera's angle or position based on the preview pictures or videos; and storing pictures or videos into a camera memory during a surf session. | 09-18-2014 |
20140267743 | SURFBOARD-MOUNTED CAMERA - A system for capturing a surfing experience includes a camera mounted on a surfboard with a camera mount providing at least three degrees of freedom to position the camera to capture a preview picture or video; and a web server coupled to the camera to render pictures or videos during a surf session. The camera may be a low profile camera designed to be flush with surface of board with same shape as surface of board. The camera may capture 3D images and may capture normal or panoramic images. | 09-18-2014 |
20140280555 | SOCIAL NETWORKING FOR SURFERS - Systems and methods are disclosed for communicating surfing experience by capturing pictures or videos of one or more surfers; uploading the pictures or videos to a remote host computer; creating at least one collage from the pictures or videos, wherein items in the collage are variably sized based on one or more predetermined factors; and sharing the collage with at least another user. | 09-18-2014 |