Patent application number | Description | Published |
20100126414 | Mounting Assembly For A Stent And A Method Of Using The Same To Coat A Stent - A mounting assembly for a stent and a method of coating a stent using the assembly are provided. | 05-27-2010 |
20100168843 | Coating For Implantable Devices And A Method Of Forming The Same - Coatings for implantable devices or endoluminal prosthesis, such as stents, are provided, including a method of forming the coatings. The coatings can be used for the delivery of an active ingredient or a combination of active ingredients. | 07-01-2010 |
20100198339 | Coating for Implantable Devices and a Method of Forming the Same - Coatings for implantable devices or endoluminal prosthesis, such as stents, are provided, including a method of forming the coatings. The coatings can be used for the delivery of an active ingredient or a combination of active ingredients. | 08-05-2010 |
20100198340 | Coating for Implantable Devices and a Method of Forming the Same - Coatings for implantable devices or endoluminal prosthesis, such as stents, are provided, including a method of forming the coatings. The coatings can be used for the delivery of an active ingredient or a combination of active ingredients. | 08-05-2010 |
20100198341 | COATING FOR IMPLANTABLE DEVICES AND A METHOD OF FORMING THE SAME - Coatings for implantable devices or endoluminal prosthesis, such as stents, are provided, including a method of forming the coatings. The coatings can be used for the delivery of an active ingredient or a combination of active ingredients. | 08-05-2010 |
20100198342 | COATING FOR IMPLANTABLE DEVICES AND A METHOD OF FORMING THE SAME - Coatings for implantable devices or endoluminal prosthesis, such as stents, are provided, including a method of forming the coatings. The coatings can be used for the delivery of an active ingredient or a combination of active ingredients. | 08-05-2010 |
20100198343 | COATING FOR IMPLANTABLE DEVICES AND A METHOD OF FORMING THE SAME - Coatings for implantable devices or endoluminal prosthesis, such as stents, are provided, including a method of forming the coatings. The coatings can be used for the delivery of an active ingredient or a combination of active ingredients. | 08-05-2010 |
20100323093 | Method of Drying Bioabsorbable Coating Over Stents - Various embodiments of methods for coating stents are described herein. Applying a composition including polymer component and solvent to a stent substrate followed by exposing the polymer component to a temperature equal to or greater than a Tg of the polymer component is disclosed. Repeating the applying and exposing one or more times to form a coating with the result that the solvent content of the coating after the final exposing step is at a level suitable for a finished stent is further disclosed. | 12-23-2010 |
20110027336 | COATINGS FOR IMPLANTABLE DEVICES COMPRISING POLYMERS OF LACTIC ACID AND METHODS FOR FABRICATING THE SAME - Coatings for an implantable medical device and a method of fabricating thereof are disclosed, the coatings comprising polymers of lactic acid. | 02-03-2011 |
20110070283 | Coating For Implantable Devices And A Method Of Forming The Same - Coatings for implantable devices or endoluminal prosthesis, such as stents, are provided, including a method of forming the coatings. The coatings can be used for the delivery of an active ingredient or a combination of active ingredients. | 03-24-2011 |
20110202126 | Polymer-Bioceramic Composite Implantable Medical Device with Different Types of Bioceramic Particles - Implantable medical devices fabricated from polymer/bioceramic composites with different types of bioceramic particles are disclosed. | 08-18-2011 |
20110244017 | Absorbable Coating For Implantable Device - The present invention provides an absorbable coating for an implantable device and the methods of making and using the same. | 10-06-2011 |
20120046640 | Coating Comprising An Elastin-Based Copolymer - The present invention is directed to medical devices including coatings. The coatings include a topcoat which includes a copolymer comprising a block of an elastin pentapeptide. The topcoat is over a layer of poly(vinyl alcohol) on a hydrophobic coating or over a porous coating comprising pores or depots that include a bioactive agent. | 02-23-2012 |
20120046756 | TREATMENT OF NASAL CAVITIES WITH STENT HAVING A SOFT OUTER LAYER - A method of treatment of sinusitis and other related diseases including disposing a radially expandable stent into a nasal passageway and radially expanding the stent in a blocked region of the nasal passageway to expand the blocked region is disclosed. The stent includes a tissue-cushioning portion composed of a hydrogel-forming or elastomeric polymer material to provide cushioning between the stent and nasal tissue and reduce irritation of the nasal tissue. | 02-23-2012 |
20120121684 | Coating Comprising A Poly(Ethylene Glycol)-Poly(Lactide-Glycolide-Caprolactone) Interpenetrating Network - Implantable medical devices are disclosed. The devices comprise a coating comprising an interpenetrating network or semi-interpenetrating network. The interpenetrating network or semi-interpenetrating network comprises poly(ethylene glycol) and an aliphatic polyester copolymer. A method of using the implantable device is also provided. | 05-17-2012 |
20120225303 | Implantable Drug Delivery Devices Having Alternating Hydrophilic And Amphiphilic Polymer Layers - An implantable drug delivery medical device with alternating hydrophilic and amphiphilic polymer layers and methods of using for the treatment of vascular disease are disclosed. | 09-06-2012 |
20120231049 | Freeze-Thaw Method For Modifying Stent Coating - Methods are disclosed for controlling the morphology and the release-rate of active agent from a coating layer for medical devices comprising a polymer matrix and one or more active agents. The methods comprise exposing a wet or dry coating to a freeze-thaw cycle. The coating layer can be used for controlled delivery of an active agent or a combination of active agents. | 09-13-2012 |
20120263759 | Coating Comprising An Elastin-Based Copolymer - A copolymer comprising a block of an elastin pentapeptide and method of making and using the copolymer are provided. The copolymer may be used as a coating on a stent. Methods of using a stent coated with the copolymer are also provided. | 10-18-2012 |
20130018299 | NANOSHELLS ON POLYMERS - Nano-constructs comprising nanoshells and methods of using the nano-constructs for treating or ameliorating a medical condition are provided. | 01-17-2013 |
20130129814 | Regional Delivery Of Therapeutic Agents For The Treatment Of Vascular Diseases - The present invention relates to the regional delivery of therapeutic agents for the treatment of vascular diseases wherein regional delivery refers to delivery of a therapeutically effective amount of the therapeutic agent to an area of the vessel that includes not only afflicted tissue but non-afflicted tissue at the periphery of the afflicted tissue as well. | 05-23-2013 |
20130224255 | Treatment Of Diabetic Patients With A Drug Eluting Stent And Adjunctive Therapy - Embodiments of the present invention include methods for the treatment, prevention, or amelioration of vascular disease in diabetic patients. The methods include both implantation of a stent including a first drug. Some embodiments include additional therapy, such as the co-administration of another drug. Some embodiments involve different stent selection for a diabetic patient compared to a non-diabetic patient. | 08-29-2013 |
20130245746 | BIOABSORBABLE STENT WITH TIME DEPENDENT STRUCTURE AND PROPERTIES AND REGIO-SELECTIVE DEGRADATION - A bioabsorbable polymeric stent with time dependent structure and properties and methods of treating a diseased blood vessel with the bioabsorable polymeric stent are disclosed. The structure and properties of the stent change with time and allow the vessel to be restored to a natural unstented state. The bioabsorbable stent loses mechanical integrity in a controlled manner due to modification of selected structural elements. | 09-19-2013 |
20130253468 | Carrier for Releasing a Therapeutic Substance in Response to the Presence of an Enzyme - A stent with a coating including a composition that releases a therapeutic substance in response to an enzyme is disclosed. The composition includes a polymer or polypeptide that includes an amino acid sequence which is recognized and cleaved by at least one of the matrix metalloproteinases (MMP). | 09-26-2013 |
20130259921 | Treatment Of Diabetic Patients With A Stent And An Adjunctive Drug Formulation - Embodiments of the present invention include methods of treating, preventing, or ameliorating a vascular disease and/or disorder in a diabetic or pre-diabetic patient. The methods include implanting a stent in a vascular region in a diabetic patient, and during the implantation procedure, delivering a drug formulation from a source other than the stent to the vascular region. The stent may be a bare metal stent, or a drug eluting stent, such as a metal stent having a coating including a drug. The drug may be everolimus, sirolimus, or a combination thereof. The drug formulation may include dexamethasone, paclitaxel, or a combination thereof. | 10-03-2013 |
20130261722 | Treatment Of Diabetic Patients With Stent And Locally Administered Adjunctive Therapy - Embodiments of the present invention include methods of treating, preventing, and/or ameliorating a vascular disease and/or disorder in a diabetic or pre-diabetic patient. The methods include implanting a stent in a vascular region in a diabetic or pre-diabetic patient, and prior to and/or during the implantation procedure, delivering a lubricant formulation to the vascular region. The stent may be a bare metal stent, or a drug eluting stent, such as a metal stent with a coating including a drug, such as everolimus or sirolimus. | 10-03-2013 |
20130261723 | Treatment Of Diabetic Patients With A Drug Eluting Stent And A Drug Coated Balloon - Embodiments of the present invention include methods for the treatment, prevention, or amelioration of vascular disease and/or disorder in diabetic patients. The methods include implantation of a stent including a drug, and the use of a drug coated balloon. The DES may be a DES having a metal body and a coating including the drug, or a bioabsorbable stent with drug in the body of the stent, in a coating on the stent, or both in the body of the stent and in a coating on the stent. | 10-03-2013 |
20130266619 | Biocompatible Polyacrylate Compositions For Medical Applications - A composition comprising a structural component comprising linear acrylic homopolymers or linear acrylic copolymers and a biobeneficial component comprising copolymers having an acrylate moiety and a biobeneficial moiety is disclosed. A medical article comprising the composition in the coating thereof and a method of fabricating the medical article are also disclosed. | 10-10-2013 |
20130273234 | Biocompatible Polyacrylate Compositions For Medical Applications - A composition comprising a structural component comprising linear acrylic homopolymers or linear acrylic copolymers and a biobeneficial component comprising copolymers having an acrylate moiety and a biobeneficial moiety is disclosed. A medical article comprising the composition in the coating thereof and a method of fabricating the medical article are also disclosed. | 10-17-2013 |
20140004250 | Methods of treatment of polymeric coatings for control of agent release rates | 01-02-2014 |
20140018907 | POLYMER-BIOCERAMIC COMPOSITE IMPLANTABLE MEDICAL DEVICE WITH DIFFERENT TYPES OF BIOCERAMIC PARTICLES - Implantable medical devices fabricated from polymer/bioceramic composites with different types of bioceramic particles are disclosed. | 01-16-2014 |
20140037831 | Coating Layers For Medical Devices And Method Of Making The Same - Methods are disclosed for controlling the morphology and the release-rate of active agent from coating layers for medical devices comprising a polymer matrix and one or more active agents. The methods comprise fixing the morphology or phase distribution of the active agent prior to removing solvent from the coating composition. The coating layers can be used for controlled the delivery of an active agent or a combination of active agents. | 02-06-2014 |
20140037832 | Coating Layers For Medical Devices And Method Of Making The Same - Methods are disclosed for controlling the morphology and the release-rate of active agent from coating layers for medical devices comprising a polymer matrix and one or more active agents. The methods comprise fixing the morphology or phase distribution of the active agent prior to removing solvent from the coating composition. The coating layers can be used for controlled the delivery of an active agent or a combination of active agents. | 02-06-2014 |
20140038907 | Coatings For Implantable Medical Devices - The present application teaches a coating having a biologically compatible compound conjugated to, or blended with, a polymer, wherein the polymer includes at least one olefin-derived unit and at least one unit derived from a vinyl alcohol, an allyl alcohol, or derivatives thereof. | 02-06-2014 |
20140127278 | Method Of Treating Vascular Disease In Diabetic Patients - The present invention relates to the treatment of vascular disease in a diabetic patient using a drug-eluting implantable medical device that releases everolimus from three distinctly loaded drug reservoir layers wherein at least one of the layers comprises at least 200 μg/cm | 05-08-2014 |
20140154400 | METHOD OF DRYING BIOABSORBABLE COATING OVER STENTS - Various embodiments of methods for coating stents are described herein. Applying a composition including polymer component and solvent to a stent substrate followed by exposing the polymer component to a temperature equal to or greater than a Tg of the polymer component is disclosed. Repeating the applying and exposing one or more times to form a coating with the result that the solvent content of the coating after the final exposing step is at a level suitable for a finished stent is further disclosed. | 06-05-2014 |
20140161862 | ABSORBABLE COATING FOR IMPLANTABLE DEVICE - The present invention provides an absorbable coating for an implantable device and the methods of making and using the same. | 06-12-2014 |
20140178454 | Coating Comprising an Amorphous Primer Layer and a Semi-Crystalline Reservoir Layer - The present invention provides a coating comprising a reservoir layer comprising a semi-crystalline polymer and a primer layer comprising an amorphous polymer on an implantable device and methods of making and using the same. | 06-26-2014 |
20140186417 | Tailored Aliphatic Polyesters for Stent Coatings - An aliphatic polyester polymer for stent coating is described. | 07-03-2014 |
20140212476 | Method of Targeting Hydrophobic Drugs to Vascular Lesions - This invention relates to the targeted delivery of hydrophobic drugs or combinations of hydrophobic drugs with photodynamic therapy agents to vascular lesions by complexation of the drugs to blood serum lipoproteins, which have an affinity for and accumulate in such vascular lesions. | 07-31-2014 |
20140356519 | ELASTIN-BASED COPOLYMERS AND METHOD OF USING - A copolymer comprising a block of an elastin pentapeptide and method of making and using the copolymer are provided. | 12-04-2014 |
20140358217 | NANOPARTICLE LOADED ELECTROSPUN IMPLANTS OR COATINGS FOR DRUG RELEASE - Medical devices, such as stents, including a fibrous layer including particles are disclosed. Methods of forming such medical devices using electrospinning are disclosed. | 12-04-2014 |
20140363563 | ELASTIN-BASED COPOLYMERS - A copolymer comprising a block of an elastin pentapeptide and method of making and using the copolymer are provided. | 12-11-2014 |
20140370073 | BIOLOGICALLY DEGRADABLE COMPOSITIONS FOR MEDICAL APPLICATIONS - A medical article is disclosed, comprising a biologically degradable AB block copolymer and a biologically degradable polymer that is capable, at equilibrium and at room temperature, of absorbing less than about 5 mass % water. | 12-18-2014 |
20140377325 | COATINGS FOR IMPLANTABLE DEVICES COMPRISING POLYMERS OF LACTIC ACID AND METHODS FOR FABRICATING THE SAME - Coatings for an implantable medical device and a method of fabricating thereof are disclosed, the coatings comprising polymers of lactic acid. | 12-25-2014 |
20140377332 | NANOSHELLS ON POLYMERS - Nano-constructs comprising nanoshells and methods of using the nano-constructs for treating or ameliorating a medical condition are provided. | 12-25-2014 |
20150045877 | REGIONAL DELIVERY OF THERAPEUTIC AGENTS FOR THE TREATMENT OF VASCULAR DISEASES - The present invention relates to the regional delivery of therapeutic agents for the treatment of vascular diseases wherein regional delivery refers to delivery of a therapeutically effective amount of the therapeutic agent to an area of the vessel that includes not only afflicted tissue but non-afflicted tissue at the periphery of the afflicted tissue as well. | 02-12-2015 |
20150073536 | Assessment of a drug eluting bioresorbable vascular scafford - A method of treating vascular disease in a patient is disclosed that comprises deploying a bioabsorbable polymer scaffold composed of a plurality of struts at a stenotic segment of an artery of a patient, wherein after the scaffold supports the segment at an increased diameter for a period of time the polymer degrades and is progressively replaced by de novo formation of malleable provisional matrix comprising proteoglycan, wherein as the scaffold becomes more malleable and becomes disconnected as it degrades, wherein following coverage of the struts by a neointima layer and loss of mechanical support provided by the scaffold, the scaffold is pulled outward by positive remodeling of the vessel wall of the scaffolded segment. | 03-12-2015 |
20150086603 | DUAL-TARGETED DRUG CARRIERS - The present invention relates to implantable medical devices containing surface-treated, dual-targeted drug carriers for treating vascular diseases. | 03-26-2015 |