Suk-Chul
Suk-Chul Bae, Cheongju KR
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20100099107 | METHOD FOR IDENTIFYING AN INTESTINAL PHENOTYPE - The present invention relates to a method for identifying cells having a predisposition to develop an intestinal phenotype, wherein the cells are characterized by the loss of expression of the RUNX3 gene and the expression of one or more intestinal marker genes. In particular, the invention is directed to the identification of cells, which exhibit an intestinal phenotype representing a precursor of gastric cancer. Furthermore, the invention discloses a method for identifying a compound inhibiting the development of an intestinal phenotype in cells having a predisposition to develop an intestinal phenotype. Finally, the invention also relates to kits of parts for performing these methods. | 04-22-2010 |
Suk-Chul Bae, Chungcheongbuk-Do KR
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20080261883 | RUNX3 GENE SHOWING ANTI-TUMOR ACTIVITY AND USE THEREOF - The present invention relates to a RUNX3 gene showing anti-tumor activity which is essentially involved in TGF-β-dependent programmed cell death (apoptosis) and use thereof. In addition, the present invention finds that RUNX3 gene expression is suppressed in the various gastric cancer and lung cancer cell lines. The suppression of the RUNX3 gene expression is due to hyper-methylation of CpG islands located around RUNX3 exon 1. The RUNX3 gene and its gene product of the present invention can be used effectively for the development of anti-cancer agents. The CpG islands around RUNX3 exon 1 could also be used not only for the development of anti-cancer agents which regulate the abnormal DNA methylation and thereby induce RUNX3 expression, and also for the development of methods for cancer diagnosis by measuring the abnormal DNA methylation. | 10-23-2008 |
Suk-Chul Bae, Chungcheongbukdo KR
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20080219962 | Method to Enhance the Bone Formation Activity of Bmp by Runx2 Acetylation - The present invention relates to a method to enhance the activity of Runx2, a major target protein of Bone Mophogenetic Protein (BMP), by Runx2 acetylation, more precisely, a method to activate BMP-mediated bone formation pathway by protecting Runx2 from ubiquitination, indicating that Runx2 is protected from degradation by the increase of Runx2 acetylation making the protein more stable. The method to enhance Runx2 activity of the present invention can be utilized for the prevention and the treatment of bone disease such as osteoporosis, osteogenesis imperfecta, periodontal disease and fracture, by inducing bone formation by inhibiting Runx2 degradation. | 09-11-2008 |
Suk-Chul Jung, Yongin-Si KR
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20130280667 | FIRING CONTAINERS - Firing containers for firing an electrode active material include one or more through openings, and protrusions protruding from an outer surface of sidewalls of each of the firing containers. The protrusions allow adjacent firing containers to be spaced apart from each other and guide the adjacent firing containers during alignment. | 10-24-2013 |
20130302683 | COMPOSITE METAL PRECURSOR, ELECTRODE ACTIVE MATERIAL PREPARED FROM THE SAME, POSITIVE ELECTRODE INCLUDING THE SAME, AND LITHIUM SECONDARY BATTERY EMPLOYING THE SAME - A composite metal precursor including a composite metal hydroxide represented by Formula 1 below, wherein an amount of magnesium (Mg) in the composite metal hydroxide is less than or equal to 0.005 wt %, an electrode active material formed from the same, a positive electrode including the same, and a lithium secondary battery employing the same: | 11-14-2013 |
Suk-Chul Lee, Gyeonggi-Do KR
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20090258104 | MOLD STRUCTURE FOR MANUFACTURING OF SECURING FILM - The present invention relates to a mold structure for manufacturing a securing film, and in particular, to a mold structure for manufacturing a securing film by alternately stacking and coupling two thin circular plates having different diameters from each other and allowing a concave structure to be formed within a transparent synthetic resin film which is closely adhered to outer circumferential surfaces of the two plates according to a height difference between the outer circumferential surface of the plate having the larger diameter and the outer circumferential surface of the plate having the smaller diameter, and a securing film which is accurately manufactured by filling the concave structure of the transparent synthetic resin film with a colored ink and coating on the resulting outer circumferential surface a transparent synthetic resin film such as a polyethylene terephthalate (PET). | 10-15-2009 |