Patent application number | Description | Published |
20110092546 | SUBSTITUTED BENZIMIDAZOLES FOR NEUROFIBROMATOSIS - The present invention relates to the use of BENZIMIDAZOLE DERIVATIVES for the preparation of a drug for the treatment of neurofibromatosis. | 04-21-2011 |
20110105521 | COMBINATION OF (A) A PHOSPHOINOSITIDE 3-KINASE INHIBITOR AND (B) A MODULATOR OF RAS/RAF/MEK PATHWAY - The invention relates to a pharmaceutical combination which comprises (a) a phosphoinositide 3-kinase inhibitor compound and (b) a compound which modulates the Ras/Raf/Mek pathway for the treatment of a proliferative disease, especially a solid tumor disease; a pharmaceutical composition comprising such a combination; the use of such a combination for the preparation of a medicament for the treatment of a proliferative disease; a commercial package or product comprising such a combination as a combined preparation for simultaneous, separate or sequential use; and to a method of treatment of a warm-blooded animal, especially a human. | 05-05-2011 |
20140057904 | Combination of (a) a phosphoinositide 3-kinase inhibitor and (b) a modulator of RAS/RAF/MEK pathway - The invention relates to a pharmaceutical combination which comprises (a) a phosphoinositide 3-kinase inhibitor compound and (b) a compound which modulates the Ras/Raf/Mek pathway for the treatment of a proliferative disease, especially a solid tumor disease; a pharmaceutical composition comprising such a combination; the use of such a combination for the preparation of a medicament for the treatment of a proliferative disease; a commercial package or product comprising such a combination as a combined preparation for simultaneous, separate or sequential use; and to a method of treatment of a warm-blooded animal, especially a human. | 02-27-2014 |
20140275136 | Method of Treating a Proliferative Disease - The present invention relates to a method of treating a patient with a serine/threonine kinase inhibitor wherein resistance to the treatment with a serine/threonine kinase inhibitor is suppressed by administering the serine/threonine kinase inhibitor on an intermittent dosing schedule. | 09-18-2014 |
20150105417 | Combination of (a) a phosphoinositide 3-kinase inhibitor and (b) a modulator of RAS/RAF/MEK pathway - The invention relates to a pharmaceutical combination which comprises (a) a phosphoinositide 3-kinase inhibitor compound and (b) a compound which modulates the Ras/Raf/Mek pathway for the treatment of a proliferative disease, especially a solid tumor disease; a pharmaceutical composition comprising such a combination; the use of such a combination for the preparation of a medicament for the treatment of a proliferative disease; a commercial package or product comprising such a combination as a combined preparation for simultaneous, separate or sequential use; and to a method of treatment of a warm-blooded animal, especially a human. | 04-16-2015 |
20150265616 | Pharmaceutical Combinations Comprising a B-RAF Inhibitor, and EGFR Inhibitor and Optionally a PI3K-Alpha Inhibitor - A pharmaceutical combination comprising (a) a B-Raf inhibitor, (b) a EGFR inhibitor and, optionally, (c) a PI3K inhibitor; the uses of such combination in the treatment of proliferative diseases; and methods of treating a subject suffering from a proliferative disease comprising administering a therapeutically effective amount of such combination. | 09-24-2015 |
Patent application number | Description | Published |
20100160381 | RAF Inhibitors for the Treatment of Thyroid Cancer - The invention relates to the use of an Raf inhibitor for the manufacture of pharmaceutical compositions for the treatment of thyroid cancer, more specifically papillary thyroid cancer (PTC); the use of a Raf inhibitor in the treatment of thyroid cancer, more specifically PTC; a method of treating warm-blooded animals including mammals, especially humans, suffering from thyroid cancer, more specifically PTC, by administering to a said animal in need of such treatment a dose effective against said disease of an Raf inhibitor. The invention also relates to the use of a Raf inhibitor in combination with a platin compound for the treatment of thyroid cancer, more specifically papillary thyroid cancer. | 06-24-2010 |
20120213867 | RAF INHIBITORS FOR THE TREATMENT OF THYROID CANCER - The invention relates to the use of an Raf inhibitor for the manufacture of pharmaceutical compositions for the treatment of thyroid cancer, more specifically papillary thyroid cancer (PTC); the use of a Raf inhibitor in the treatment of thyroid cancer, more specifically PTC; a method of treating warm-blooded animals including mammals, especially humans, suffering from thyroid cancer, more specifically PTC, by administering to a said animal in need of such treatment a dose effective against said disease of an Raf inhibitor. The invention also relates to the use of a Raf inhibitor in combination with a platin compound for the treatment of thyroid cancer, more specifically papillary thyroid cancer. | 08-23-2012 |
Patent application number | Description | Published |
20110218674 | REMOTE PRESENCE SYSTEM INCLUDING A CART THAT SUPPORTS A ROBOT FACE AND AN OVERHEAD CAMERA - A tele-presence system that includes a cart. The cart includes a robot face that has a robot monitor, a robot camera, a robot speaker, a robot microphone, and an overhead camera. The system also includes a remote station that is coupled to the robot face and the overhead camera. The remote station includes a station monitor, a station camera, a station speaker and a station microphone. The remote station can display video images captured by the robot camera and/or overhead camera. By way of example, the cart can be used in an operating room, wherein the overhead camera can be placed in a sterile field and the robot face can be used in a non-sterile field. The user at the remote station can conduct a teleconference through the robot face and also obtain a view of a medical procedure through the overhead camera. | 09-08-2011 |
20140135990 | REMOTE PRESENCE SYSTEM INCLUDING A CART THAT SUPPORTS A ROBOT FACE AND AN OVERHEAD CAMERA - A tele-presence system that includes a cart. The cart includes a robot face that has a robot monitor, a robot camera, a robot speaker, a robot microphone, and an overhead camera. The system also includes a remote station that is coupled to the robot face and the overhead camera. The remote station includes a station monitor, a station camera, a station speaker and a station microphone. The remote station can display video images captured by the robot camera and/or overhead camera. By way of example, the cart can be used in an operating room, wherein the overhead camera can be placed in a sterile field and the robot face can be used in a non-sterile field. The user at the remote station can conduct a teleconference through the robot face and also obtain a view of a medical procedure through the overhead camera. | 05-15-2014 |
20150286789 | REMOTE PRESENCE SYSTEM INCLUDING A CART THAT SUPPORTS A ROBOT FACE AND AN OVERHEAD CAMERA - A tele-presence system that includes a cart. The cart includes a robot face that has a robot monitor, a robot camera, a robot speaker, a robot microphone, and an overhead camera. The system also includes a remote station that is coupled to the robot face and the overhead camera. The remote station includes a station monitor, a station camera, a station speaker and a station microphone. The remote station can display video images captured by the robot camera and/or overhead camera. By way of example, the cart can be used in an operating room, wherein the overhead camera can be placed in a sterile field and the robot face can be used in a non-sterile field. The user at the remote station can conduct a teleconference through the robot face and also obtain a view of a medical procedure through the overhead camera. | 10-08-2015 |
Patent application number | Description | Published |
20080276180 | METHOD AND SYSTEM CONFIGURED TO ASSESS A FEE FOR COMMUNICATION FACILITATION REGARDING PUBLICATION INFORMATION - A method and system are configured to assess a fee for communication facilitation regarding publication information. An electronic publication system includes a publication module configured to generate a user interface based on an information search. The user interface includes search result information associated with a first entity and communication initiation information associated with the first entity. The communication initiation information includes identification information configured to identify a contact module of the first entity. The communication initiation information is configured to be selectable to facilitate communication between a second entity and the first entity. The publication system also includes a receiving module configured to receive a lead data record from a communication system that facilitates communication between the first entity and a second entity via the contact module upon selection of the communication initiation information generated from the publication module. The publication system also includes a fee assessment module configured to receive the lead data record from the receiving module and to assess a fee to the first entity based on the lead data record. | 11-06-2008 |
20100121733 | METHOD AND SYSTEM TO ENABLE A FIXED PRICE PURCHASE WITHIN A MULTI-UNIT ONLINE AUCTION ENVIRONMENT - A method includes presenting to a buyer a multi-unit auction, permitting the buyer to bid one or more of a price and a number of units in the auction, and permitting the buyer to re-bid in the auction. The auction includes a rule that prevents the buyer from reducing the price in the re-bid, and the auction further includes a rule that prevents the buyer from reducing the number of units in the re-bid. | 05-13-2010 |
20130007631 | METHOD AND SYSTEM CONFIGURED TO ASSESS A FEE FOR COMMUNICATION FACILITATION REGARDING PUBLICATION INFORMATION - A method and system are configured to assess a fee for communication facilitation. An electronic publication system includes a publication module configured to generate a user interface. The user interface includes search result information associated with a first entity and communication initiation information associated with the first entity. The communication initiation information includes identification information configured to identify a contact module of the first entity. The communication initiation information may be selectable to facilitate communication with the first entity. The publication system also includes a receiving module configured to receive a lead data record from a communication system for communication between the first entity and a second entity via the contact module. The publication system also includes a fee assessment module configured to receive the lead data record and to assess a fee to the first entity. | 01-03-2013 |
20130317931 | METHOD AND SYSTEM TO ENABLE A FIXED PRICE PURCHASE WITHIN A MULTI-UNIT ONLINE AUCTION ENVIRONMENT - A method includes presenting to a buyer a multi-unit auction, permitting the buyer to bid one or more of a price and a number of units in the auction, and permitting the buyer to re-bid in the auction. The auction includes a rule that prevents the buyer from reducing the price in the re-bid, and the auction further includes a rule that prevents the buyer from reducing the number of units in the re-bid. | 11-28-2013 |
Patent application number | Description | Published |
20100063415 | METHODS AND DEVICES FOR AUTOMATED BIOPSY AND COLLECTION OF SOFT TISSUE - A biopsy device and related method are disclosed. The biopsy device disclosed includes a needle having a lateral opening for receiving tissue. The needle may be rotatable with respect to a portion of the biopsy device, such as a housing of the biopsy device, and the needle may be offset from a center of the housing. A hollow cutter is disclosed for cutting tissue received in the lateral opening of the needle. | 03-11-2010 |
20110160611 | METHODS AND DEVICES FOR BIOPSY AND COLLECTION OF SOFT TISSUE - A biopsy device may include a housing and a disposable biopsy assembly releasably received in the housing. The disposable biopsy assembly may include a cutter coaxially disposed with respect to a needle, and a plurality of gears may be engaged when the disposable biopsy sample is inserted in the housing. A tissue sample holder may be disposed within housing. | 06-30-2011 |
20130197392 | METHODS AND DEVICES FOR BIOPSY AND COLLECTION OF SOFT TISSUE - A biopsy system includes a cannula, a cutter, and a tissue sample holder. The cannula includes a closed distal end and a lateral tissue receiving port. The cutter is coaxially disposed with the cannula for severing tissue received in the tissue receiving port. The tissue sample holder includes a plurality of discrete tissue sample compartments. The biopsy system transports individual tissue samples to the discrete tissue sample compartments of the tissue sample holder. | 08-01-2013 |
20130197393 | METHODS AND DEVICES FOR BIOPSY AND COLLECTION OF SOFT TISSUE - A biopsy system includes a housing, a cannula, a hollow cutter, and a rotatable tissue sample holder. The cannula extends distally from the housing and is rotatable with respect to the housing. The cutter is movable with respect to the cannula for severing tissue received by the cannula. The tissue sample holder includes a plurality of separate tissue sample compartments, the tissue sample compartments being disposed about an axis of rotation of the tissue sample holder. The biopsy system transports severed tissue samples to the tissue sample holder. | 08-01-2013 |
20140088412 | METHODS AND DEVICES FOR BIOPSY AND COLLECTION OF SOFT TISSUE - A biopsy device includes a needle assembly, a hollow cutter, and a tissue sample housing. The needle assembly includes a needle extending distally from a portion of the biopsy device. The needle includes a tissue receiving opening. The hollow cutter is coaxially arranged with respect to the needle and severs tissue received in the tissue receiving opening of the needle. The tissue sample housing includes a vacuum port. | 03-27-2014 |
20140330163 | METHODS AND DEVICES FOR BIOPSY AND COLLECTION OF SOFT TISSUE - A biopsy system includes a housing, a cannula, a hollow cutter, and a rotatable tissue sample holder. The cannula extends distally from the housing and is rotatable with respect to the housing. The cutter is movable with respect to the cannula for severing tissue received by the cannula. The tissue sample holder includes a plurality of separate tissue sample compartments, the tissue sample compartments being disposed about an axis of rotation of the tissue sample holder. The biopsy system transports severed tissue samples to the tissue sample holder. | 11-06-2014 |
Patent application number | Description | Published |
20150103642 | DIAGNOSING CONNECTIVITY IN A NETWORK - Diagnosing connectivity in a network includes obtaining information from a network wherein the network is a hybrid network including software-defined networking (SDN) network components and other network components, querying a SDN controller for network metrics of the network, and diagnosing a connectivity issue in the network based on the information from the network and the network metrics. | 04-16-2015 |
20150103672 | DATA FLOW PATH DETERMINATION - A method of determining a data flow path within a computing network includes, with the processor executing a data flow path determination module, determining a number of data flow paths between a first node and a second node within the computing network, and with a with the processor executing a graphical user interface (GUI) module, displaying the data flow paths to a user. | 04-16-2015 |
20150113143 | NETWORK RESOURCE AUTOMATION MANAGEMENT - A method for resource automation management includes creating a service model by receiving dragged and dropped abstracted service units into a workspace and receiving connections between the abstracted service units to represent a communication path. The method further includes storing the service model in a computer readable memory and simulating, with a computational processor, the service model in a zone model representing resources and topology in the computer network. | 04-23-2015 |
Patent application number | Description | Published |
20160042870 | HIGH ENERGY DENSITY STORAGE DEVICE - A device and method for providing electrical energy storage of high specific energy density. The device contains one or more layers of high dielectric constant material, such as Barium Titanate or Hexagonal Barium Titanate, sandwiched between electrode layers made up of a variety of possible conducting materials. The device includes additional insulating layers including carbon, such as carbon formed into diamond or a diamond-like arrangement for providing between the electrodes and the dielectric layer to provide for very high breakdown voltages. The layers can be created by a variety of methods including laser deposition and assembled to form a capacitor device provides the high energy density storage. | 02-11-2016 |
20160043524 | SLAB LASER AND AMPLIFIER - A laser for high power applications. The laser is a lamp driven slab design with a face to face beam propagation scheme and an end reflection that redirects the amplified radiation back out the same input surface. Also presented is a side to side larger amplifier configuration, permitting very high average and peak powers due to the electrical efficiency of absorbing energy into the crystal, optical extraction efficiency, and scalability of device architecture. Cavity filters adjacent to pump lamps convert the unusable UV portion of the pump lamp spectrum into light in the absorption band of the slab laser thereby increasing the overall pump efficiency. The angle of the end reflecting surface is changed to cause the exit beam to be at a different angle than the inlet beam, thereby eliminating the costly need to separate the beams external to the laser with the subsequent loss of power. | 02-11-2016 |
20160073488 | DIELECTRIC WALL ACCELERATOR UTILIZING DIAMOND OR DIAMOND LIKE CARBON - Provided are a plurality of embodiments, including, but not limited to, a device for generating efficient low and high average power output Gamma Rays via relativistic particle bombardment of element targets using an efficient particle injector and accelerator at low and high average power levels suitable for element transmutation and power generation with an option for efficient remediation of radioisotope release into any environment. The devices utilize diamond or diamond-like carbon materials and active cooling for improved performance. | 03-10-2016 |
Patent application number | Description | Published |
20100238680 | LASER ENERGY SOURCE DEVICE AND METHOD - An innovative device and method for providing a laser system utilizing high efficiency diode lasers and optionally the high quality beam characteristics of a crystal gain medium single mode laser by utilizing an optical and mechanical method of forming the beam and directing it to the desired target. | 09-23-2010 |
20110239981 | OSCILLATING PISTON ENGINE - An engine configuration that places multiple pistons on one or two oscillating discs. The engine can be configured to operate as an internal combustion engine that uses diesel fuel, gasoline, or natural gas, or it can be configured as an expander to convert high pressure high temperature gas to rotary power. For any given set of choices of numbers of pistons and sizes of pistons, disks, and gears, there are disclosed dimensional constraints useful for more efficient functioning of the engine. This engine is especially suited as a driver for electrical power generation as it delivers high torque at low engine speeds, among other uses. Its compact design results in high power to weight ratios. | 10-06-2011 |
20120230048 | LASER ENERGY SOURCE DEVICE AND METHOD - A device and method for providing a laser system utilizing a plurality of high efficiency diode lasers interacting with a concave mirror and an integrating convex mirror and light transmitter for converging the laser beamlets emitted by the diode lasers, and optionally providing high quality beam characteristics of a crystal gain medium single mode laser by utilizing an optical and mechanical method of forming the beam and directing it to the desired target. | 09-13-2012 |
20130301662 | SLAB LASER AND AMPLIFIER - An economical slab laser for high power applications. The laser is a lamp driven slab design with face-to-face beam propagation and an end reflection that redirects the amplified radiation back out the input surface. Also presented is a side-to-side larger amplifier configuration, permitting very high average and peak powers due to the electrical efficiency of converting and getting energy into the crystal, optical extraction efficiency, and scalability of device architecture. Cavity filters adjacent to pump lamps convert the unusable UV portion of the pump lamp spectrum into light in the absorption band of the slab laser thereby increasing the overall pump efficiency. The angle of the end reflecting surface is changed to cause the exit beam to be at a different angle than the inlet beam, thereby eliminating the need to separate the beams external to the laser with the subsequent loss of power. | 11-14-2013 |
20140179959 | PLASMA ARC FURNACE AND APPLICATIONS - A Plasma Arc Reformer for creating a useful fuel, such as Methanol, using any of Methane, Municipal Solid Waste, farm or forest waste, coal orchar rock from oil shale production, petrochemical hydrocarbons, (any carbon containing charge), water, and/or Municipal Sewage, as the source material. A High temperature Plasma Arc de-polymerizes the source material into atoms which, upon partial cooling, creates a gas stream rich in CO and H | 06-26-2014 |
20140293504 | HIGH ENERGY DENSITY STORAGE DEVICE - A device and method for providing electrical energy storage of high specific energy density. The device contains a plurality of layers of high dielectric constant material, such as Barium Titanate or Hexagonal Barium Titanate, sandwiched between electrode layers made up of a variety of possible conducting materials. The device includes additional insulating layers, such as Diamond Like Carbon Coating, between the electrodes that provide for very high breakdown voltages. Layers are created by a variety of methods and assembled to form the device that is the High Energy Density Storage Device. | 10-02-2014 |
20140355146 | LASER ENERGY SOURCE DEVICE - A device and method for providing a laser system utilizing high efficiency lasers emitters and optionally the high quality beam characteristics of a crystal gain medium single mode laser for emitting beamlets and utilizing an optical and mechanical method of forming the beam and directing it to the desired target using both a concave and a partially reflective convex mirror to reflect the beamlets, with the convex mirror transmitting a portion of the beamlets to a transmission medium for emitting the beamlets as a laser beam. | 12-04-2014 |
20150059681 | POLYGON OSCILLATING PISTON ENGINE - A Polygon Oscillating Piston Engine having multiple pistons on one of two oscillating disks. Each piston moves in a straight line along one of the sides of a polygon within a cylindrical chamber, while the oscillating disks move in an arc about a central shaft. The difference in the straight motion of the piston and angular motion of the oscillating disk is accommodated by a slip sleeve within the piston that slides on a peg or bar mounted to each disk. The engine can be configured to operate as an internal combustion engine that uses diesel fuel, gasoline, or natural gas, or it can be configured as an expander to convert high pressure high temperature gas to rotary power. This engines compact design results in a high power-to-weight ratio. | 03-05-2015 |
20150077066 | HIGH ENERGY DENSITY STORAGE DEVICE - An energy storage device for providing electrical energy storage of high specific energy density for use in consumer and commercial devices and for storing power to be provided to an electrical power grid. An example of the energy storage device has a plurality of layers of high dielectric constant material, such as Barium Titanate or Hexagonal Barium Titanate, sandwiched between electrode layers made up of a variety of possible conducting materials. The example device includes additional insulating layers, such as Diamond-Like Carbon Coating, between the electrodes that provide for very high breakdown voltages. | 03-19-2015 |
20150128896 | OSCILLATING PISTON ENGINE - An engine configuration that uses multiple opposing piston pairs to form respective expansion chambers for expanding a gas within to move the pistons to drive a main shaft. The engine can be configured to operate as an internal combustion engine that uses diesel fuel, gasoline, or natural gas, or it can be configured as an expander to convert high pressure high temperature gas to rotary power. The pistons may be mounted on the circumference of one or more disks. For any given set of choices of numbers of pistons and sizes of pistons, disks, and gears, there are disclosed dimensional constraints useful for more efficient functioning of the engine. This engine can be provided with a compact design which results in high power to weight ratios. | 05-14-2015 |
20150311064 | SLAB LASER AND AMPLIFIER AND METHOD OF USE - A slab laser and its method of use for high power applications including the manufacture of semiconductors and deposition of diamond and/or diamond-like-carbon layers, among other materials. A lamp driven slab design with a face-to-face beam propagation scheme and an end reflection that redirects the amplified radiation back out the same input surface is utilized. A side-to-side amplifier configuration permitting very high average and peak powers having scalability is also disclosed. Cavity filters adjacent to pump lamps convert the normally unusable UV portion of the pump lamp spectrum into light in the absorption band of the slab laser, thereby increasing the overall pump efficiency. The angle of the end reflecting surface is changed to cause the exit beam to be at a different angle than the inlet beam, thereby eliminating the costly need to separate the beams external to the laser with the subsequent loss of power. | 10-29-2015 |