Patent application number | Description | Published |
20080206298 | Enhanced biological autologous tissue adhesive composition and methods of preparation and use - The invention includes a composition useful for preparing a tissue sealant for use on a patient, comprising: autologous fibrinogen, an activating agent and at least one supplement. The invention includes a method of treating a disc having at least one defect, comprising: introducing a composition into the disc, wherein the composition comprises autologous fibrinogen and an activating agent, and wherein the composition forms fibrin. | 08-28-2008 |
20090054994 | Methods and kits for prophylactically reinforcing degenerated spinal discs and facet joints near a surgically treated spinal section - A method is effective for prophylactically treating discs and facet joints near a spinal section that requires surgery. The method comprises the steps of performing a surgical procedure on a section of a spine, and reinforcing a disc or a facet joint adjacent to the surgically treated area with an effective amount of an injected, in situ curable biocompatible matrix or biocompatible polymeric compound. The procedure delays or prevents the development of permanent or irreversible degenerative changes in the treated disc and/or facet joint, thus offering the spinal surgery patient a higher probability of long-term success for arresting disc and facet joint degeneration and prevention of latent adjacent disc/facet joint problems. | 02-26-2009 |
20100137816 | Injection of fibrin sealant including an anesthetic in spinal applications - A method of treating a disc that is leaking nucleus pulposus through at least one defect in the annulus fibrosus. The method includes injecting a fibrin sealant into the disc to reduce at least a portion of the at least one defect, wherein the fibrin sealant injected into the disc comprises an anesthetic, fibrinogen and an activating compound, wherein at least a portion of the fibrin forms after injection, with the proviso that a corticosteroid is absent from the fibrin sealant injected into the disc. | 06-03-2010 |
20100233148 | Injection of fibrin sealant including an anesthetic in spinal applications - A method of treating a disc that is leaking nucleus pulposus through at least one defect in the annulus fibrosus. The method includes injecting a fibrin sealant into the disc to reduce at least a portion of the at least one defect, wherein the fibrin sealant injected into the disc comprises an anesthetic, fibrinogen and an activating compound, wherein at least a portion of the fibrin forms after injection, with the proviso that a corticosteroid is absent from the fibrin sealant injected into the disc. | 09-16-2010 |
20110213464 | INJECTION OF FIBRIN SEALANT IN THE ABSENCE OF CORTICOSTEROIDS IN SPINAL APPLICATIONS - A method and kit for treating a disc that is leaking nucleus pulposus through at least one defect in the annulus fibrosus. The method includes injecting a fibrin sealant into the disc to reduce at least a portion of the at least one defect, wherein the fibrin sealant injected into the disc comprises fibrinogen and an activating compound, wherein at least a portion of the fibrin forms after injection, with the proviso that a corticosteroid is absent from the fibrin sealant injected into the disc. | 09-01-2011 |
20120156284 | ENHANCED BIOLOGICAL AUTOLOGOUS TISSUE ADHESIVE COMPOSITION AND METHODS OF PREPARATION AND USE - The invention includes a composition useful for preparing a tissue sealant for use on a patient, comprising: autologous fibrinogen, an activating agent and at least one supplement. The invention includes a method of treating a disc having at least one defect, comprising: introducing a composition into the disc, wherein the composition comprises autologous fibrinogen and an activating agent, and wherein the composition forms fibrin. | 06-21-2012 |
20120328600 | INJECTION OF FIBRIN SEALANT USING RECONSTITUTED COMPONENTS IN SPINAL APPLICATIONS - A method of treating a disc that is leaking nucleus pulposus through at least one defect in the annulus fibrosus. The method includes injecting a fibrin sealant into the disc to reduce at least a portion of the at least one defect, wherein the fibrin sealant injected into the disc comprises fibrinogen and an activating compound, wherein at least a portion of the fibrin forms after injection, wherein the fibrinogen, the activating compound or both has been reconstituted with a solution containing at least one additive, with the proviso that a corticosteroid is absent from the fibrin sealant injected into the disc. | 12-27-2012 |
20140052070 | Injection Of Fibrin Sealant Including An Anesthetic In Spinal Applications - A method of treating a disc that is leaking nucleus pulposus through at least one defect in the annulus fibrosus. The method includes injecting a fibrin sealant into the disc to reduce at least a portion of the at least one defect, wherein the fibrin sealant injected into the disc comprises an anesthetic, fibrinogen and an activating compound, wherein at least a portion of the fibrin forms after injection, with the proviso that a corticosteroid is absent from the fibrin sealant injected into the disc. | 02-20-2014 |