Patent application number | Description | Published |
20110135806 | MANUFACTURING METHODS FOR COVERING ENDOLUMINAL PROSTHESES - The disclosure relates to a method for coating a target. The method includes providing a target and an electrospinning apparatus. The target comprises a first surface and an opposing second surface. The electrospinning apparatus comprises a mandrel, a mask including an aperture, a reservoir loaded with a solution, and an orifice fluidly coupled to the reservoir. The mandrel is located adjacent the target second surface. The orifice is located at a distance from the target first surface. The mask is located intermediate the orifice and the target first surface. The solution is electrospun through the mask aperture onto the target first surface. In one example the target is an endoluminal prosthesis. | 06-09-2011 |
20140180398 | Bioabsorbable Medical Devices and Methods of Use Thereof - One aspect provides implantable medical devices including a bioabsorbable structure having a surface and having a coating layer on at least a portion of the surface. In certain embodiments, the coating layer includes a releasable bioactive and provides for a controlled absorption of the bioabsorbable structure upon implantation in a human or veterinary patient. Another aspect provides methods treating a disease including implanting such a device in a vessel of a human or veterinary patient. | 06-26-2014 |
20140188250 | MODIFIABLE MEDICAL GRAFTS AND RELATED METHODS AND APPARATUSES - Described are medical graft materials and devices which can be usefully modified with liquid additives such as cell suspensions, bioactive agents, or combinations of these. Also described are methods for making and using these medical graft materials and devices. | 07-03-2014 |
20140276368 | CELL INJECTION NEEDLE - Methods and apparatus are provided for treating tissue with apparatus that includes an priming portion for initiating a healing response in the tissue to be treated, and which delivers a bioactive agent during or after preparing tissue adjacent the apparatus, as by generating or aiding a healing, regeneration or repair response in the tissue. The priming portion may comprise an abrasive surface, fluid ejection ports, and/or stimulation by electrical, thermal, or light energy. | 09-18-2014 |
20140315847 | DRUG ELUTING GRAFT CONSTRUCTS AND METHODS - The present invention provides, in certain aspects, medical graft products that incorporate multiple drug depots in and/or on the products. One such product is a sheet graft construct, for example for tissue support that includes a sheet graft material with a plurality of drug depots. The drug depots can be hardened deposits formed directly onto the sheet graft material and/or can be capable of eluting a drug for a minimum of 72 hours. | 10-23-2014 |
20150025649 | HIP STEM PROSTHESIS - A hip stem prosthesis is provided for treating a deficient hip joint. | 01-22-2015 |
20150065425 | PRODUCTS COMPRISING AN EXTRACELLULAR MATRIX MATERIAL AND OSTEOGENIC PROTEIN - Osteogenic compositions include a decellularized extracellular matrix tissue and bone morphogenic protein, preferably BMP-2. The compositions make beneficial use of the BMP, which can be used at relatively low doses and can bind to native components (e.g., native sulfated glycosaminoglycans such as heparin and/or heparan sulfate) remaining in the decellularized extracellular matrix tissue. Methods for preparation and use of such compositions are also described. The compositions and related methods can be used in the treatment of diseased or damaged bone tissue. | 03-05-2015 |
20150065947 | CELL-SEEDED COMPOSITIONS AND METHODS USEFUL FOR TREATING BONE REGIONS - Compositions and methods for treating diseased or damaged bone, preferably ischemic and/or necrotic bone, include the use of a combination of endothelial progenitor cells and mesenchymal stem cells, desirably also in conjunction with a collagenous extracellular matrix tissue. Methods for preparation of such compositions are also described. | 03-05-2015 |