Patent application number | Description | Published |
20080255160 | MAPK/ERK KINASE INHIBITORS - Compounds of the following formula are provided for use with MEK: | 10-16-2008 |
20080312307 | MAPK/ERK KINASE INHIBITORS - Compounds are provided for inhibition of MEK that comprise: | 12-18-2008 |
20090124595 | MAPK/ERK KINASE INHIBITORS - Compounds of the following formula are provided for use with MEK: | 05-14-2009 |
20090281092 | POLO-LIKE KINASE INHIBITORS - Compounds of the following formula are provided for use with kinases: | 11-12-2009 |
20090291938 | POLO-LIKE KINASE INHIBITORS - Compounds of the following formula are provided for use with kinases: | 11-26-2009 |
20100075973 | POLO-LIKE KINASE INHIBITORS - The present invention provides PLK inhibitors of the formula | 03-25-2010 |
20100093767 | Mitotic Kinase Inhibitors - The invention relates to inhibitors of enzymes that disrupt the assembly and function of the mitotic spindle, compositions comprising the inhibitors of Formula (I), kits and articles of manufacture comprising the inhibitors and inhibitor compositions, and methods of using the inhibitors and inhibitor compositions. The inhibitors and inhibitor compositions are useful for treating, preventing or modulating diseases in which mitotic kinesins, including kinesin-like spindle protein (KSP), may be involved; symptoms of such diseases; or the effect of other physiological events mediated by mitotic kinesins, including KSP. | 04-15-2010 |
20100113413 | MAPK/ERK Kinase Inhibitors - Compounds of the substituted 1,3-dialkyl-2,4-dioxo-6-(arylamino)-1,2,3,4-tetrahydropyrimidine-5-hydroxamic acids, show below: | 05-06-2010 |
20100130518 | MAPK/ERK KINASE INHIBITORS - Compounds of the following formula are provided for use with MEK (I): wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds. | 05-27-2010 |
20100204471 | MAPK/ERK KINASE INHIBITORS - Compounds, pharmaceutical compositions, kits and methods are provided for use with MEK that comprise a compound selected from the group consisting of: wherein the variables are as defined herein. | 08-12-2010 |
20100210635 | RENIN INHIBITORS - Compounds, pharmaceutical compositions, kits and methods are provided for use with Renin that comprise a compound selected from the group consisting of: wherein the variables are as defined herein. | 08-19-2010 |
20110065733 | MAPK/ERK KINASE INHIBITORS - Compounds of the following formula are provided for use with MEK: | 03-17-2011 |
20110082111 | POLO-LIKE KINASE INHIBITORS - Compounds of the following formula are provided for use with kinases: | 04-07-2011 |
20110190261 | MAPK/ERK Kinase Inhibitors - Compounds of the substituted 1,3-dialkyl-2,4-dioxo-6-(pyrimidinylamino)-1,2,3,4-tetrahydropyrimidine-5-hydroxamic acids, show below: | 08-04-2011 |
20110201818 | POLO-LIKE KINASE INHIBITORS - Compounds of the following formula are provided for use with kinases: | 08-18-2011 |
20120202999 | MAPK/ERK KINASE INHIBITORS - Compounds of the following formula are provided for use with MEK: | 08-09-2012 |