| Patent application number | Description | Published |
|---|
| 20080213462 | Methods For Coating An Implantable Device - A process for coating an implantable device is disclosed. In this process, at least one implantable device is tumbled. As the implantable device is being tumbled, a coating substance is introduced to coat the implantable device with the coating substance. | 09-04-2008 |
| 20080230000 | Stent Spin Coating Apparatus - A system or device for spin coating an implantable medical device, such as a stent, is disclosed. The device includes a coating table to support the stent, the stent being positioned on top of the coating table and supported on the table by a support fixture. The coating table has an axis of rotation. The axis of rotation of the table can intersect a center of the mass of the stent. A driving means can be provided for rotating the stent about the longitudinal axis of the stent and for rotating the coating table about the axis of rotation. | 09-25-2008 |
| 20080233268 | Stent Spin Coating Method - A method is disclosed for spin coating a stent. The method comprises applying a coating substance to the stent; rotating the stent about an axis of rotation, the axis of rotation being perpendicular to a longitudinal axis of the stent; and rotating the stent about the longitudinal axis of the stent contemporaneously with rotating the stent about the axis of rotation. The axis of rotation can intersect a center of the mass of the stent. | 09-25-2008 |
| 20080234812 | Stent spin coating method - A method is disclosed for spin coating a stent. The method comprises conducting the following acts at the same time: applying a coating substance to the stent; rotating the stent about a first axis of rotation; and rotating the stent about a second axis of rotation. | 09-25-2008 |
| 20080262606 | POLYMERS CONTAINING SILOXANE MONOMERS - A polymer of siloxanes as flexibility monomers and strength monomers is provided. It is also provided a polymer blend that contains a polymer formed of siloxane monomers and strength monomers and another biocompatible polymer. The biocompatible polymer or polymer blend described herein and optionally a bioactive agent can form a coating on an implantable device such as a drug-delivery stent. The implantable device can be used for treating or preventing a disorder such as atherosclerosis, thrombosis, restenosis, hemorrhage, vascular dissection or perforation, vascular aneurysm, vulnerable plaque, chronic total occlusion, claudication, anastomotic proliferation for vein and artificial grafts, bile duct obstruction, ureter obstruction, tumor obstruction, or combinations thereof. | 10-23-2008 |
| 20080268018 | Method for forming crystallized therapeutic agents on a medical device - A method of crystallizing a therapeutic agent in a coating on an implantable medical device, and uses thereof, are disclosed. | 10-30-2008 |
| 20080286332 | Implantable medical devices with a topcoat layer of phosphoryl choline acrylate polymer for reduced thrombosis, and improved mechanical properties - The present invention relates to implantable medical devices coated with phosphoryl choline acrylate polymer topcoat layer, an acrylate copolymer layer containing a therapeutic agent, and their use in the treatment of vascular diseases. | 11-20-2008 |
| 20090004243 | Biodegradable triblock copolymers for implantable devices - The present invention is directed to polymeric materials made of biodegradable, bioabsorbable triblock copolymers and implantable devices (e.g., drug-delivery stents) containing such polymeric materials. The polymeric materials may also contain at least one therapeutic substance. The polymeric materials are formulated so as to improve the mechanical and adhesion properties, degradation, biocompatibility and drug permeability of such materials and, thus, implantable devices formed of such materials. | 01-01-2009 |
| 20090004286 | COMPOSITIONS FOR ACHIEVING A THERAPEUTIC EFFECT IN AN ANATOMICAL STRUCTURE AND METHODS OF USING THE SAME - Compositions and methods of using the compositions to achieve a therapeutic effect are provided. | 01-01-2009 |
| 20090012243 | BIOBENEFICIAL POLYAMIDE/POLYETHYLENE GLYCOL POLYMERS FOR USE WITH DRUG ELUTING STENTS - This disclosure covers polymers, which are useful in medical device applications. The polymers comprise at least two different blocks, at least one L1 block with the formula | 01-08-2009 |
| 20090012259 | BIOBENEFICIAL POLYAMIDE/POLYETHYLENE GLYCOL POLYMERS FOR USE WITH DRUG ELUTING STENTS - Provided herein is a coating comprising a polymer. The polymer comprises at least two different blocks, at least one L1 block with the formula | 01-08-2009 |
| 20090012606 | BIOBENEFICIAL POLYAMIDE/POLYETHYLENE GLYCOL POLYMERS FOR USE WITH DRUG ELUTING STENTS - This disclosure provides a method device and a method of forming the medical device. The medical device comprises a coating comprising a polymer. The polymer comprises at least two different blocks, at least one L1 block with the formula | 01-08-2009 |
| 20090053391 | Method Of Coating A Drug-Releasing Layer Onto A Substrate - This invention relates to processes for coating a substrate with a drug-containing layer in which the microstructure of the resulting dry drug reservoir layer is not a function of solvent removal. | 02-26-2009 |
| 20090104241 | RANDOM AMORPHOUS TERPOLYMER CONTAINING LACTIDE AND GLYCOLIDE - The present invention provides an amorphous terpolymer for a coating on an implantable device for controlling release of drug and methods of making and using the same | 04-23-2009 |
| 20090104247 | Coating Designs For The Tailored Release Of Dual Drugs From Polymeric Coatings - Provided herein are coating designs for the tailored release of two therapeutic agents from polymer coatings and methods of making and using the same. | 04-23-2009 |
| 20090136556 | System And Method For Coating Implantable Devices - A method and system of coating an implantable device, such as a stent, are provided. | 05-28-2009 |
| 20090148591 | Methods to improve adhesion of polymer coatings over stents - Methods are disclosed to improved adhesion of polymer coatings over polymer surfaces of stents which include plasma treatment, applying an adhesion promoting layer, surface treatments with solvents, and mechanical roughening techniques. | 06-11-2009 |
| 20090248146 | COATINGS FOR IMPLANTABLE MEDICAL DEVICES - Coatings for implantable medical devices comprising non-fouling moieties or polymers chemically bonded to the surface of the device via chelating structures, and methods of fabricating the coatings are disclosed. | 10-01-2009 |
| 20090252780 | COATINGS FOR IMPLANTABLE MEDICAL DEVICES - Coatings for implantable medical devices comprising non-fouling moieties or polymers chemically bonded to the surface of the device via chelating structures, and methods of fabricating the coatings are disclosed. | 10-08-2009 |
| 20090269479 | Method For Biostable Inclusion Of A Biobeneficial Agent On An Outermost Surface Of An Implantable Medical Device - The current invention is directed to a method of protecting UV or visible light sensitive drugs from the effects of UV or visible radiation used to form covalent bonds between a biobeneficial material and the outermost surface of an implantable medical device in order to lessen the foreign body response to the device. | 10-29-2009 |
| 20090274741 | POLYMERS CONTAINING POLY(ESTER AMIDES) AND AGENTS FOR USE WITH MEDICAL ARTICLES AND METHODS OF FABRICATING THE SAME - Polymers containing poly(ester amides) and agents for use with medical articles and methods of fabricating the same are disclosed. The medical article generally comprises an implantable substrate having a coating, and the coating contains a polymer comprising a polymeric product of a reaction comprising a polyol, a polycarboxylic acid, an amino acid and an agent. | 11-05-2009 |
| 20090291111 | COATING COMPRISING AN AMORPHOUS PRIMER LAYER AND A SEMI-CRYSTALLINE RESERVOIR LAYER - The present invention provides a coating comprising a reservoir layer comprising a semi-crystalline polymer and a primer layer comprising an amorphous polymer on an implantable device and methods of making and using the same. | 11-26-2009 |
| 20090297583 | POLY(ESTER AMIDES) FOR THE CONTROL OF AGENT-RELEASE FROM POLYMERIC COMPOSITIONS - The present invention generally encompasses a medical article, such as a medical device or coating comprising an agent or combination of agents, wherein the agent is distributed throughout a polymeric matrix. The polymeric matrix comprises an agent and a poly(ester amide) having a design that was preselected to provide a predetermined release rate of the combination of agents from the medical article. | 12-03-2009 |
| 20090299007 | BIOLOGICALLY ABSORBABLE COATINGS FOR IMPLANTABLE DEVICES BASED ON POLYESTERS AND METHODS FOR FABRICATING THE SAME - Polymers containing polyesters and, optionally, agents for use with medical articles and methods of fabricating the same are disclosed. The medical article generally comprises an implantable substrate having a coating, and the coating contains a polymer comprising a polymeric product of a reaction comprising a polyol and a polycarboxylic acid. | 12-03-2009 |
| 20090311301 | COATING CONSTRUCT CONTAINING POLY(VINYL ALCOHOL) - A method of forming a surface layer that includes a hydroxyl polymer on a substrate coating on a medical device is provided. | 12-17-2009 |
| 20090319031 | Bioabsorbable Polymeric Stent With Improved Structural And Molecular Weight Integrity - Various embodiments of the present invention include implantable medical devices such as stents manufactured from polymers, and more particularly, biodegradable polymers including biodegradable polyesters. Other embodiments include methods of fabricating implantable medical devices from polymers. The devices and methods utilize one or more stabilizers, where each stabilizer may be chosen from the following categories: free radical scavengers, peroxide decomposers, catalyst deactivators, water scavengers, and metal scavengers. | 12-24-2009 |
| 20090319036 | Medical Devices Made From Polymers With End Group Modification For Improved Thermal Stability - Implantable medical devices and methods of forming thereof made from polymers with end groups providing improved thermal stability are disclosed. Implantable medical devices made from such polymers including stabilizing agents are additionally disclosed. | 12-24-2009 |
| 20090326645 | Methods Of Application Of Coatings Composed Of Hydrophobic, High Glass Transition Polymers With Tunable Drug Release Rates - The present invention relates to methods of applying a drug—polymer coating layer onto an implantable medical device or another substrate, and the use of a choice of solvents to adjust the release of the drug from the coating. The drug to polymer ratio is about 1:1 to 1:3 on a mass basis. The polymer and the drug are hydrophobic. | 12-31-2009 |
| 20100003231 | POLYMERS OF FLUORINATED MONOMERS AND HYDROCARBON MONOMERS - It is provided an implantable device including a polymer blend that contains a polymer formed of fluorinated monomers and hydrocarbon monomers and another biocompatible polymer. | 01-07-2010 |
| 20100003303 | POLYMERS OF FLUORINATED MONOMERS AND HYDROCARBON MONOMERS - It is provided a method of treating a disorder, the method comprising implanting in a patient an implantable device including a polymer formed of fluorinated monomers and hydrocarbon monomers and another biocompatible polymer. | 01-07-2010 |
| 20100004396 | POLYMERS OF FLUORINATED MONOMERS AND HYDROCARBON MONOMERS - It is provided a polymer blend that contains a polymer formed of fluorinated monomers and hydrocarbon monomers and another biocompatible polymer. | 01-07-2010 |
| 20100016533 | POLYMERS OF FLUORINATED MONOMERS AND HYDROCARBON MONOMERS - It is a polymer formed of fluorinated monomers and hydrocarbon monomers and another biocompatible polymer. | 01-21-2010 |
| 20100063570 | COATING ON A BALLOON COMPRISING A POLYMER AND A DRUG - A coating on a balloon of a medical device is provided. The coating comprises a drug and a polymer. Also provided are methods of forming and using the coating. | 03-11-2010 |
| 20100082095 | Coatings Including Dexamethasone Derivatives And Analogs And Olimus Drugs - The present invention encompasses a coating on the surface of a substrate and the coated substrates. The coating includes a polymer, an olimus drug (sirolimus, everolimus, zotarolimus, etc.), and a dexamethasone derivative. The polymer may be a hydrophobic polymer, preferably a fluoropolymer, and more preferably a fluoropolymer with at least 25% vinylidene fluoride by weight. | 04-01-2010 |
| 20100104734 | COATED STENT AND METHOD OF MAKING THE SAME - A coated implantable medical device and a method of coating an implantable medical device is disclosed, the method includes applying a composition onto the device and drying the composition at elevated temperature in an environment having increased relative humidity. A pre-screening method for a manufacturing lot of coated stents to determine the number of drug coating layers for a desired drug release rate is disclosed. The method including coating and testing small groups of stents, and applying the results of the tests to determine the number of drug coating layers to apply to the manufacturing lot of stents. | 04-29-2010 |
| 20100119571 | IMPLANTABLE DEVICES FORMED ON NON-FOULING METHACRYLATE OR ACRYLATE POLYMERS - Implantable devices formed of or coated with a material that includes a polymer having a non-fouling acrylate or methacrylate polymer are provided. The implantable device can be used for treating or preventing a disorder such as atherosclerosis, thrombosis, restenosis, hemorrhage, vascular dissection or perforation, vascular aneurysm, vulnerable plaque, chronic total occlusion, patent foramen ovale, claudication, anastomotic proliferation for vein and artificial grafts, bile duct obstruction, ureter obstruction, tumor obstruction, or combinations thereof. | 05-13-2010 |
| 20100136213 | Thermal Treatment of a Drug Eluting Implantable Medical Device - A coating and a method of coating an implantable medical device, such as a stent, is disclosed. The method includes subjecting the coating to a thermal condition such as a temperature above the glass transition temperature of a polymer included in the coating. | 06-03-2010 |
| 20100137471 | Compositions Containing Fast-Leaching Plasticizers For Improved Performance Of Medical Devices - Medical implants containing a temporary plasticizer, methods of producing such implants, and methods of using the implants in treating a disease, or ameliorating one or more symptoms thereof, in a subject are provided. | 06-03-2010 |
| 20100154705 | System for Coating a Tubular Implantable Medical Device - A system for coating a tubular implantable medical device, such as a stent, can include a rotatable applicator and a rotatable support for the medical device. The axes of rotation of applicator and the support can be substantially non-parallel. | 06-24-2010 |
| 20100168843 | Coating For Implantable Devices And A Method Of Forming The Same - Coatings for implantable devices or endoluminal prosthesis, such as stents, are provided, including a method of forming the coatings. The coatings can be used for the delivery of an active ingredient or a combination of active ingredients. | 07-01-2010 |
| 20100189876 | Balloon Catheter for Delivering Therapeutic Agents - A drug delivery device for delivering therapeutic agents and a method of making such a device is disclosed. The device includes an inflatable balloon. A microporous coating covers a portion of the outer surface of the wall of the balloon. The thickness of the coating and the size of the micropores can permit desirable delivery of a substance from the micropores of the coating and into the tissue of a patient's lumen. | 07-29-2010 |
| 20100198339 | Coating for Implantable Devices and a Method of Forming the Same - Coatings for implantable devices or endoluminal prosthesis, such as stents, are provided, including a method of forming the coatings. The coatings can be used for the delivery of an active ingredient or a combination of active ingredients. | 08-05-2010 |
| 20100198340 | Coating for Implantable Devices and a Method of Forming the Same - Coatings for implantable devices or endoluminal prosthesis, such as stents, are provided, including a method of forming the coatings. The coatings can be used for the delivery of an active ingredient or a combination of active ingredients. | 08-05-2010 |
| 20100198341 | COATING FOR IMPLANTABLE DEVICES AND A METHOD OF FORMING THE SAME - Coatings for implantable devices or endoluminal prosthesis, such as stents, are provided, including a method of forming the coatings. The coatings can be used for the delivery of an active ingredient or a combination of active ingredients. | 08-05-2010 |
| 20100198342 | COATING FOR IMPLANTABLE DEVICES AND A METHOD OF FORMING THE SAME - Coatings for implantable devices or endoluminal prosthesis, such as stents, are provided, including a method of forming the coatings. The coatings can be used for the delivery of an active ingredient or a combination of active ingredients. | 08-05-2010 |
| 20100198343 | COATING FOR IMPLANTABLE DEVICES AND A METHOD OF FORMING THE SAME - Coatings for implantable devices or endoluminal prosthesis, such as stents, are provided, including a method of forming the coatings. The coatings can be used for the delivery of an active ingredient or a combination of active ingredients. | 08-05-2010 |
| 20100266659 | IMPLANTABLE DEVICES FORMED ON NON-FOULING METHACRYLATE OR ACRYLATE POLYMERS - Implantable devices formed of or coated with a material that includes a polymer having a non-fouling acrylate or methacrylate polymer are provided. The implantable device can be used for treating or preventing a disorder such as atherosclerosis, thrombosis, restenosis, hemorrhage, vascular dissection or perforation, vascular aneurysm, vulnerable plaque, chronic total occlusion, patent foramen ovale, claudication, anastomotic proliferation for vein and artificial grafts, bile duct obstruction, ureter obstruction, tumor obstruction, or combinations thereof. | 10-21-2010 |
| 20100285085 | BALLOON COATING WITH DRUG TRANSFER CONTROL VIA COATING THICKNESS - A coated medical device, such a balloon or stent. The coating includes a therapeutic agent having a thickness of the coating is between about 1.5 to 10 μm and less than 30% of the coating remains on the balloon post delivery to a vessel. | 11-11-2010 |
| 20100297211 | BIOBENEFICIAL POLYAMIDE/POLYETHYLENE GLYCOL POLYMERS FOR USE WITH DRUG ELUTING STENTS - This disclosure provides a medical device and a method of forming the medical device. The medical device comprises a coating comprising a type-one polymer and a type-two polymer. The type-one polymer comprises at least two different blocks, at least one L1 block with the formula | 11-25-2010 |
| 20100323093 | Method of Drying Bioabsorbable Coating Over Stents - Various embodiments of methods for coating stents are described herein. Applying a composition including polymer component and solvent to a stent substrate followed by exposing the polymer component to a temperature equal to or greater than a Tg of the polymer component is disclosed. Repeating the applying and exposing one or more times to form a coating with the result that the solvent content of the coating after the final exposing step is at a level suitable for a finished stent is further disclosed. | 12-23-2010 |
| 20100330145 | BIOBENEFICIAL COATING COMPOSITIONS AND METHODS OF MAKING AND USING THEREOF - A biobeneficial coating composition for coating an implantable device, such as a drug eluting stent, a method of coating the device with the composition, and an implantable device coated with the composition are provided. | 12-30-2010 |
| 20100330259 | BIOBENEFICIAL COATING COMPOSITIONS AND METHODS OF MAKING AND USING THEREOF - A biobeneficial coating composition for coating an implantable device, such as a drug eluting stent, a method of coating the device with the composition, and an implantable device coated with the composition are provided. | 12-30-2010 |
| 20100331969 | BIOBENEFICIAL COATING COMPOSITIONS AND METHODS OF MAKING AND USING THEREOF - A biobeneficial coating composition for coating an implantable device, such as a drug eluting stent, a method of coating the device with the composition, an implantable device coated with the composition, and a method of treating a disorder are provided. | 12-30-2010 |
| 20110027336 | COATINGS FOR IMPLANTABLE DEVICES COMPRISING POLYMERS OF LACTIC ACID AND METHODS FOR FABRICATING THE SAME - Coatings for an implantable medical device and a method of fabricating thereof are disclosed, the coatings comprising polymers of lactic acid. | 02-03-2011 |
| 20110033517 | COATINGS FOR IMPLANTABLE MEDICAL DEVICES COMPRISING HYDROPHILIC SUBSTANCES AND METHODS FOR FABRICATING THE SAME - A segmented polyurethane and an amphiphilic random or block copolymer are disclosed. The segmented polyurethane and the amphiphilic random or block copolymer can be used for fabricating a coating for an implantable medical device such as a stent. | 02-10-2011 |
| 20110059227 | System and Method for Coating a Stent - A systems and method for reducing coating defects on a stent may involve a support apparatus comprising wire cage for carrying a stent. The support apparatus may have no structure that extends inside the stent. A support apparatus may include a plurality of wires that pass through the stent but do not pass through the midplane of the stent. A support apparatus may contact only the proximal ends of the stent. The method may involve keeping the stent in motion during a spray coating process to prevent the stent from having a point remain in continuous contact with a support apparatus. | 03-10-2011 |
| 20110070283 | Coating For Implantable Devices And A Method Of Forming The Same - Coatings for implantable devices or endoluminal prosthesis, such as stents, are provided, including a method of forming the coatings. The coatings can be used for the delivery of an active ingredient or a combination of active ingredients. | 03-24-2011 |
| 20110137243 | Coating On A Balloon Device - The present invention provides a hygroscopic coating on a balloon for an implantable device and methods of making and using the same. | 06-09-2011 |
| 20110244017 | Absorbable Coating For Implantable Device - The present invention provides an absorbable coating for an implantable device and the methods of making and using the same. | 10-06-2011 |
| 20110245904 | Implantable Prosthesis With Depot Retention Feature - A prosthesis for intraluminal drug delivery can comprise a plurality of interconnected struts that form a tubular scaffold structure. The struts include through-holes with an inner surface configured to retain a bioabsorbable depot. The bioabsorbable depot includes a drug-polymer composition that hydrolytically degrades upon implantation. The inner surface of the through-hole can be an entirely smooth and continuous area that is concave or convex, with no geometric discontinuities. The inner surface of the through-hole can include any number of constricted and distended regions to form grooves of a size and shape carefully selected to engage a corresponding geometric feature of the bioabsorbable depot. | 10-06-2011 |
| 20110245907 | Implantable Prosthesis Having Through-Holes - A prosthesis for intraluminal drug delivery can comprise a plurality of interconnected struts and links that form a tubular structure. The struts and links can have luminal surfaces facing radially inward, abluminal surfaces facing radially outward, and side surfaces connecting the luminal surfaces to the abluminal surfaces. At least some of the struts and links have through-holes in the side surfaces. At least some of the through-holes contain a drug, which can be carried in a polymer matrix. | 10-06-2011 |
| 20110251677 | Coating Designs For The Tailored Release Of Dual Drugs From Polymeric Coatings - Provided herein are coating designs for the tailored release of two therapeutic agents from polymer coatings and methods of making and using the same. | 10-13-2011 |
| 20110262530 | SUSTAINED RELEASE OF APO A-I MIMETIC PEPTIDES AND METHODS OF TREATMENT - A method including advancing a delivery device through a lumen of a blood vessel to a particular region in the blood vessel; and introducing a composition including a sustained-release carrier and an apolipoprotein A-I (Apo A-I) synthetic mimetic peptide into a wall of the blood vessel at the particular region, wherein the peptide has a property that renders the peptide effective in reverse cholesterol transport. A composition including an apolipoprotein A-I (Apo A-I) synthetic peptide, or combination of an Apo A-I synthetic mimetic peptide and an Acyl CoA cholesterol: acyltransferase (ACAT) inhibitor in a form suitable for delivery into a blood vessel, the peptide including an amino acid sequence in an order reverse to an order of various Apo A-I mimetic peptides, or endogenous Apo A-I analogs, or a chimera of helix 1 and helix 9 of endogenous Apo A-I. | 10-27-2011 |
| 20110268690 | POLYMERS CONTAINING POLY(HYDROXYALKANOATES) AND AGENTS FOR USE WITH MEDICAL ARTICLES AND METHODS OF FABRICATING THE SAME - Compositions comprising poly(hydroxyalkanoates) and agents for use with medical articles are described. | 11-03-2011 |
| 20110274733 | POLYMERS CONTAINING POLY(HYDROXYALKANOATES) AND AGENTS FOR USE WITH MEDICAL ARTICLES AND METHODS OF FABRICATING THE SAME - Embodiments of the present invention provides medical devices comprising poly(hydroxyalkanoates) and agents. | 11-10-2011 |
| 20110281019 | Direct Fluid Coating Of Drug Eluting Balloon - A system and method for coating an expandable member of a medical device comprises providing a dispenser in fluid communication with a fluid source with the dispenser having at least one outlet to dispense fluid of the fluid source therefrom. The outlet(s) of the dispenser is positioned proximate a surface of an expandable member, with relative movement between the outlet(s) and the surface of the expandable member established along a coating path, and fluid is dispensed from the dispenser to form a substantially continuous bead of fluid between the at least one outlet and the surface of the expandable member along the coating path, and simultaneously drying the fluid while dispensing the fluid from the dispenser to control flow of fluid on the surface of the expandable member. The fluid source can include a variety of therapeutic agents. | 11-17-2011 |
| 20110281020 | Maintaining A Fixed Distance During Coating Of Drug Coated Balloon - A system and method for coating an expandable member of a medical device comprising a support structure to support the expandable member and a dispenser positioned with at least one outlet proximate a surface of an expandable member. A drive assembly establishes relative movement between the at least one outlet and the surface of the expandable member to apply fluid on the surface of the expandable member along a coating path. A guide maintains a substantially fixed distance between the at least one outlet and the surface of the expandable member during relative movement therebetween by displacing the expandable member relative to the at least one outlet. | 11-17-2011 |
| 20110293706 | NANOSHELLS ON POLYMERS - Nano-constructscomprising nanoshells and methods of using the nano-constructs for treating or ameliorating a medical condition are provided. | 12-01-2011 |
| 20110311605 | Coating Designs For The Tailored Release Of Dual Drugs From Polymeric Coatings - Provided herein are coating designs for the tailored release of two therapeutic agents from polymer coatings and methods of making and using the same. | 12-22-2011 |
| 20120003379 | METHODS TO IMPROVE ADHESION OF POLYMER COATINGS OVER STENTS - Methods are disclosed to improved adhesion of polymer coatings over polymer surfaces of stents which include plasma treatment, applying an adhesion promoting layer, surface treatments with solvents, and mechanical roughening techniques. | 01-05-2012 |
| 20120004721 | METHODS TO IMPROVE ADHESION OF POLYMER COATINGS OVER STENTS - Methods are disclosed to improved adhesion of polymer coatings over polymer surfaces of stents which include plasma treatment, applying an adhesion promoting layer, surface treatments with solvents, and mechanical roughening techniques. | 01-05-2012 |
| 20120015019 | Drug Coated Balloon With In-Situ Formed Drug Containing Microspheres - The current invention relates to methods of forming a coating that involves the in-situ formation of drug microspheres. The coating may be applied to a medical device, such as a catheter balloon or a stent. Coated devices and methods of treatment therewith are also encompassed within the embodiments of the present invention. | 01-19-2012 |
| 20120034222 | Nitric Oxide Generating Medical Devices - Medical devices having a catalyst capable of catalyzing the generation of nitric oxide in vivo and methods of treating a vascular condition using the devices are provided. | 02-09-2012 |
| 20120035107 | COMPOSITIONS FOR ACHIEVING A THERAPEUTIC EFFECT IN AN ANATOMICAL STRUCTURE - Compositions and methods of using the compositions are provided for forming an embolus within a region of an anatomical lumen for a transitory period in order to achieve a therapeutic effect. | 02-09-2012 |
| 20120064141 | Drug-Coated Balloon With Location-Specific Plasma Treatment - Method of coating an expandable member, e.g. balloon, is provided, the method comprising providing an expandable member having an outer surface. The method includes a plasma treatment with a supply of gas performed on at least a portion of the outer surface of the expandable member. A therapeutic agent is applied on at least the plasma treated portion of the outer surface of the expandable member after the plasma treatment is performed. The plasma treatment can reduce the adhesion of therapeutic agent to the surface of the expandable member. A medical device made by the disclosed method is also provided. | 03-15-2012 |
| 20120064223 | Drug Coated Balloon Surface Relaxation Process To Minimize Drug Loss - Method of coating an expandable member is provided. The method comprises providing an expandable member having deflated and fully expanded configurations, and inflating the expandable member with a select amount of inflation medium, the select amount of inflation medium applied at a nominal pressure, disposing a therapeutic agent on at least a portion of the expandable member; and partially deflating the expandable member, wherein partially deflating includes releasing an initial amount of inflation medium from the expandable member such that the expandable member partially re-folds. The therapeutic agent can be dried on the expandable member, and a remaining amount of inflation medium can be withdrawn such that the expandable member resumes the completely folded configuration. | 03-15-2012 |
| 20120065722 | Bioabsorbable Superficial Femoral Stent Patterns With Designed To Break Links - Bioabsorbable polymeric stent patterns with linking struts between rings that are designed to fail upon deployment of the stent are disclosed. | 03-15-2012 |
| 20120165922 | METHOD OF MODIFYING A COATING ON A MEDICAL DEVICE - Method of modifying the coating of a surface of a medical device by applying a coating to the surface of the medical device, exposing the medical device to an environmental condition that alters the coating morphology, and drying the coating on the medical device. The disclosed subject matter also provides a coated medical device whose one or more surfaces have been modified by this method. | 06-28-2012 |
| 20120185034 | Coating For Implantable Devices And A Method Of Forming The Same - Coatings for implantable devices or endoluminal prosthesis, such as stents, are provided, including a method of forming the coatings. The coatings can serve as a primer coating for subsequent coatings that can be used for the delivery of an active ingredient or a combination of active ingredients. | 07-19-2012 |
| 20120216905 | Methods Of Drug Loading A Hollow Stent With A High Viscosity Formulation - A method of loading a composition into a structural element of a stent, where the structural element is defined by a lumen and at least one opening to access the lumen. The composition may include a therapeutic agent. In some embodiments, the composition has characteristics such that at a temperature of 20° C. to 30° C. and a pressure of one atmosphere, the viscosity of the composition is about 10 cP or greater than 10 cP. | 08-30-2012 |
| 20120216907 | Methods Of Loading A Hollow Stent With A Drug Or Drug Formulation - A method of loading a composition into a structural element of a stent, where the structural element is defined by a lumen and at least one opening to access the lumen. The composition may comprise a therapeutic agent, and wherein at a temperature of 30° C. and at one atmosphere, the composition may be in a solid state or semi-solid state. | 08-30-2012 |
| 20120216908 | Methods Of Drug Loading A Hollow Stent By Immersion - A method of loading a composition into a structural element of a stent, where the structural element is defined by a lumen and at least one opening to access the lumen. The structural element, or a stent having such a structural element, is immersed in a solution or a composition, and the composition or solution is allowed to fill the lumen. The composition or solution may comprise a therapeutic agent. | 08-30-2012 |
| 20120216912 | Cover Sleeve and Apparatus for Loading Material into a Stent Strut - An apparatus for loading material into a stent strut can comprise a cover sleeve. The cover sleeve is elastic so that it can reduce in diameter so as to press against the stent strut, and expand in diameter so as to be spaced apart from the stent strut. The stent strut can include a lumen into which material is injected. When pressed against the stent strut, the cover sleeve seals side openings to the lumen and prevents injected material from leaking out of the side openings during the injection process. | 08-30-2012 |
| 20120216913 | Vacuum Chamber And Apparatus For Loading Material Into A Stent Strut - An apparatus for loading material into a stent strut can comprise a chamber capable of maintaining an internal pressure below pressure external to the chamber. The chamber carries within it the stent and the material to be loaded into a lumen within the stent strut. Pressure within the chamber is decreased. The decreased pressure can draw the material into lumen. The decreased pressure can draw air out of the lumen so that, after a subsequent increase in pressure in the chamber, the material is drawn into the lumen. | 08-30-2012 |
| 20120216914 | Suction Pump And Apparatus For Loading Material Into A Stent Strut - An apparatus for loading material into a stent strut can comprise a suction pump connected to an opening to a lumen within the stent strut. The stent strut is immersed in the material. As the suction pump draws gas out of the lumen, the material is drawn into side openings to the lumen. | 08-30-2012 |
| 20120216916 | Pressure Chamber And Apparatus For Loading Material Into A Stent Strut - An apparatus for loading material into a stent strut can comprise a chamber in which a pressure gradient is formed when gas moves through the pressure chamber. While injecting material into a lumen within the stent strut, the pressure gradient inhibits material from leaking out of side holes to the lumen. | 08-30-2012 |
| 20120219696 | Methods Of Loading A Hollow Stent Using A Solvent - A method of loading a composition into a structural element of a stent, where the structural element is defined by a lumen and at least one opening to access the lumen. The composition that is injected may include a therapeutic agent, and it includes a solvent and optionally an excipient. The solvent has a low boiling point, such as less than a temperature of 20° C., and the solution is injected at a condition of temperature and pressure such that the solution is a liquid or a supercritical fluid state. | 08-30-2012 |
| 20120315376 | Method And System To Maintain A Fixed Distance During Coating Of A Medical Device - Method and system to coat an expandable member of a medical device comprising a support structure to support the expandable member and an applicator positioned with at least one outlet proximate a surface of an expandable member. A drive assembly establishes relative movement between the at least one outlet and the surface of the expandable member to apply fluid on the surface of the expandable member along a coating path. A tracking mechanism maintains a substantially fixed distance between the at least one outlet and the surface of the expandable member during relative movement therebetween by displacing the at least one outlet relative to the expandable member. | 12-13-2012 |
| 20120330405 | Implantable Medical Devices With A Topcoat Layer Of Phosphoryl Choline For Reduced Thrombosis, And Improved Mechanical Properties - The present invention relates to implantable medical devices coated with phosphoryl choline acrylate polymer topcoat layer and their use in the treatment of vascular diseases. | 12-27-2012 |
| 20130017312 | METHODS OF MANUFACTURE OF BIORESORBABLE AND DURABLE STENTS WITH GROOVED LUMENAL SURFACES FOR ENHANCED RE-ENDOTHELIALIZATIONAANM Pacetti; Stephen D.AACI San JoseAAST CAAACO USAAGP Pacetti; Stephen D. San Jose CA US - Methods of making bioabsorbable stents with grooved lumenal surfaces for enhanced re-endothelialization are disclosed. Methods include molding grooves on the lumenal surface of coated bioresorbable and durable stents. Methods further include molding grooves on lumenal surfaces of a bioresorbable tube and forming a scaffold from the tube. | 01-17-2013 |
| 20130018299 | NANOSHELLS ON POLYMERS - Nano-constructs comprising nanoshells and methods of using the nano-constructs for treating or ameliorating a medical condition are provided. | 01-17-2013 |
| 20130041129 | Controlling Moisture In And Plasticization Of Bioresorbable Polymer For Melt Processing - Methods and systems for controlling the moisture content of biodegradable and bioresorbable polymer resin during extrusion above a lower limit that allows for plasticization of the polymer resin melt and below an upper limit to reduce or prevent molecular weight loss are disclosed. Methods are further disclosed involving plasticization of a polymer resin for feeding into an extruder with carbon dioxide and freon. | 02-14-2013 |
| 20130129814 | Regional Delivery Of Therapeutic Agents For The Treatment Of Vascular Diseases - The present invention relates to the regional delivery of therapeutic agents for the treatment of vascular diseases wherein regional delivery refers to delivery of a therapeutically effective amount of the therapeutic agent to an area of the vessel that includes not only afflicted tissue but non-afflicted tissue at the periphery of the afflicted tissue as well. | 05-23-2013 |
| 20130129816 | THERAPEUTIC COMPOSITION WITH ENHANCED ENDOTHELIUM TARGETING - A composition that includes nanoparticles with binding affinity for platelets, and methods for using this composition to treat vascular disease are disclosed. | 05-23-2013 |
| 20130138081 | METHOD AND MEDICAL DEVICE HAVING TISSUE ENGAGING MEMBER FOR DELIVERY OF A THERAPEUTIC AGENT - Method of delivering a therapeutic agent includes delivering at least a portion of a medical device within a vasculature. The medical device includes a tubular member having a proximal end and distal end defining a longitudinal axis therebetween, an expandable member proximate the distal end of the tubular member, a tissue engaging member proximate the expandable member, a sheath disposed over the tissue engaging member, and a therapeutic agent disposed on at least the expandable member or the tissue engaging member. The method further includes deploying the tissue engaging member at a select location by displacement of the sheath relative the tissue engaging member, inflating the expandable member to engage the therapeutic agent with a vessel wall, deflating the expandable member, and withdrawing the medical device from the vasculature. | 05-30-2013 |
| 20130142940 | STENT SPIN COATING METHOD AND SYSTEM - A method for removing excess coating from a stent involves simultaneously applying a coating substance to the stent, rotating the stent about a first axis of rotation, and rotating the stent about a second axis of rotation parallel to the first axis of rotation. An apparatus for removing excess coating from a stent includes a first system configured to rotate the stent about an axis of rotation, a fixture configured to support the stent such that a longitudinal axis of the stent is generally parallel to the axis of rotation, and a second system configured to rotate the stent about the longitudinal axis of the stent while the stent is supported by the fixture. | 06-06-2013 |
| 20130172982 | POLYMER STENT WITH BREAK-AWAY LINKS FOR ENHANCED STENT RETENTION - Polymer stents with break-away links and methods of forming the links for improved stent retention on an expandable member during delivery are disclosed. | 07-04-2013 |
| 20130190725 | MEDICAL DEVICE HAVING TISSUE ENGAGING MEMBER AND METHOD FOR DELIVERY OF A THERAPEUTIC AGENT - Medical device includes a tubular member having a proximal end and distal end defining a longitudinal axis therebetween, an expandable member proximate the distal end of the tubular member having at least one axial fold in a deflated condition, a tissue engaging member comprising at least one straight wire extending along at least part of the longitudinal axis of the expandable member, and a therapeutic agent disposed on at least the expandable member or the tissue engaging member. The at least one straight wire of the tissue engaging member is located inside the at least one fold of the expanded member when in the deflated condition. The tissue engaging member is configured for deployment at a select location upon inflation of the expandable member. A method of delivering a therapeutic agent is also provided. | 07-25-2013 |
| 20130204353 | RADIOPAQUE INTRALUMINAL STENTS COMPRISING COBALT-BASED ALLOYS CONTAINING ONE OR MORE PLATINUM GROUP METALS, REFRACTORY METALS, OR COMBINATIONS THEREOF - Embodiments are directed to radiopaque implantable structures (e.g., stents) formed of cobalt-based alloys that comprise cobalt, chromium and one or more platinum group metals, refractory metals, precious metals, or combinations thereof. Platinum group metals include platinum, palladium, ruthenium, rhodium, osmium, and iridium. Refractory metals include zirconium, niobium, rhodium, molybdenum, hafnium, tantalum, tungsten, rhenium, and precious metals include silver and gold. In one embodiment, the one or more included platinum group or refractory metals substitute at least partially for nickel, such that the alloy exhibits reduced nickel content, or is substantially nickel free. The stents exhibit improved radiopacity as compared to similar alloys including greater amounts of nickel. | 08-08-2013 |
| 20130259911 | BIOBENEFICIAL COATING COMPOSITIONS AND METHODS OF MAKING AND USING THEREOF - A biobeneficial coating composition for coating an implantable device, such as a drug eluting stent, a method of coating the device with the composition, an implantable device coated with the composition, and a method of treating a disorder are provided. | 10-03-2013 |
| 20130261735 | MAGNESIUM ALLOY IMPLANTS WITH CONTROLLED DEGRADATION - Stents or scaffolds made from magnesium or magnesium alloys including additives or barrier coatings that modify the corrosion rate of the stent are disclosed. Methods of forming barrier coatings that modify the corrosion rate of the stent are disclosed. | 10-03-2013 |
| 20130268045 | SEGMENTED SCAFFOLDS AND DELIVERY THEREOF FOR PERIPHERAL APPLICATIONS - Segmented scaffolds composed of disconnected scaffold segments are disclosed. System of and methods for delivery of the segmented scaffolds are disclosed. | 10-10-2013 |
| 20130276412 | METHODS OF DRUG LOADING A HOLLOW STENT BY IMMERSION - A method of loading a composition into a structural element of a stent, where the structural element is defined by a lumen and at least one opening to access the lumen. The structural element, or a stent having such a structural element, is immersed in a solution or a composition, and the composition or solution is allowed to fill the lumen. The composition or solution may comprise a therapeutic agent. | 10-24-2013 |
| 20130287833 | Nitric Oxide Generating Medical Devices - Medical devices having a catalyst capable of catalyzing the generation of nitric oxide in vivo and methods of treating a vascular condition using the devices are provided. | 10-31-2013 |
| 20130303496 | Method Of Treating Vascular Lesions - The present invention relates to the treatment of vascular lesions using low doses of an mTOR inhibitor together with a low dose of a glucocorticoid on an implantable medical device, wherein the treatment is particularly beneficial when the patient is a diabetic or is suffering from an abnormally long or diffuse lesion. | 11-14-2013 |
| 20130304182 | FLOW REGULATION VALVE FOR CONTROLLING INFLATION RATE OF A BALLOON DEPLOYING A SCAFFOLD - An apparatus and method for controlling inflation pressure, pressurization rate, and volumetric flow rate of a balloon during deployment of a stent or scaffold is disclosed. | 11-14-2013 |
| 20130324637 | Polymers Of Fluorinated Monomers And Hydrocarbon Monomers - It is a polymer formed of fluorinated monomers and hydrocarbon monomers and another biocompatible polymer. | 12-05-2013 |
| 20130325100 | STENT DELIVERY CATHETER WITH IMPROVED STENT RETENTION AND METHOD OF MAKING SAME - A stent delivery catheter system having a catheter with stent releasably mounted on a stent retention portion of the catheter for delivery and deployment within a patient's body lumen, and a method of mounting the stent on the stent retention portion of the catheter. The method generally includes exposing the stent retention portion and/or the stent to a solvent, the solvent being in the vapor phase. The vapor phase solvent typically softens the stent retention portion of the catheter, and/or, in one embodiment in which the stent has a coating on the stent body, the vapor phase solvent softens the stent coating. In a presently preferred embodiment, the stent polymeric coating has a therapeutic agent, and the method of the invention prevents or inhibits disadvantageously affecting the therapeutic agent coating during mounting of the stent on the catheter. | 12-05-2013 |
| 20130330390 | Biobeneficial Coating Compositions And Methods Of Making And Using Thereof - A biobeneficial coating composition for coating an implantable device, such as a drug eluting stent, a method of coating the device with the composition, and an implantable device coated with the composition are provided. | 12-12-2013 |
| 20130330392 | Polymers Of Fluorinated Monomers And Hydrocarbon Monomers - It is provided an implantable device including a polymer blend that contains a polymer formed of fluorinated monomers and hydrocarbon monomers and another biocompatible polymer. | 12-12-2013 |
| 20130330393 | Polymers Of Fluorinated Monomers And Hydrocarbon Monomers - It is provided a method of treating a disorder, the method comprising implanting in a patient an implantable device including a polymer formed of fluorinated monomers and hydrocarbon monomers and another biocompatible polymer. | 12-12-2013 |
| 20130344047 | Methods And Composition For Treating Heart Failure And Ischemia - Methods and compositions for treating heart failure by administration of beneficial agents to the heart. | 12-26-2013 |
| 20140004250 | Methods of treatment of polymeric coatings for control of agent release rates | 01-02-2014 |
| 20140005334 | Polymers Of Fluorinated Monomers And Hydrocarbon Monomers | 01-02-2014 |
| 20140025160 | IMPLANTABLE PROSTHESIS HAVING THROUGH-HOLES - A prosthesis for intraluminal drug delivery can comprise a plurality of interconnected struts and links that form a tubular structure. The struts and links can have luminal surfaces facing radially inward, abluminal surfaces facing radially outward, and side surfaces connecting the luminal surfaces to the abluminal surfaces. At least some of the struts and links have through-holes in the side surfaces. At least some of the through-holes contain a drug, which can be carried in a polymer matrix. | 01-23-2014 |
| 20140033504 | Method of Making Implantable Prosthesis with Depot Retention Feature - A prosthesis for intraluminal drug delivery can comprise a plurality of interconnected struts that form a tubular scaffold structure. The struts include through-holes with an inner surface configured to retain a bioabsorbable depot. The bioabsorbable depot includes a drug-polymer composition that hydrolytically degrades upon implantation. The inner surface of the through-hole can be an entirely smooth and continuous area that is concave or convex, with no geometric discontinuities. The inner surface of the through-hole can include any number of constricted and distended regions to form grooves of a size and shape carefully selected to engage a corresponding geometric feature of the bioabsorbable depot. | 02-06-2014 |
| 20140037833 | METHOD FOR COATING A STENT - A systems and method for reducing coating defects on a stent may involve a support apparatus comprising wire cage for carrying a stent. The support apparatus may have no structure that extends inside the stent. A support apparatus may include a plurality of wires that pass through the stent but do not pass through the midplane of the stent. A support apparatus may contact only the proximal ends of the stent. The method may involve keeping the stent in motion during a spray coating process to prevent the stent from having a point remain in continuous contact with a support apparatus. | 02-06-2014 |
| 20140041580 | SYSTEM FOR COATING A STENT - A systems and method for reducing coating defects on a stent may involve a support apparatus comprising wire cage for carrying a stent. The support apparatus may have no structure that extends inside the stent. A support apparatus may include a plurality of wires that pass through the stent but do not pass through the midplane of the stent. A support apparatus may contact only the proximal ends of the stent. The method may involve keeping the stent in motion during a spray coating process to prevent the stent from having a point remain in continuous contact with a support apparatus. | 02-13-2014 |
| 20140065093 | Compositions For Achieving A Therapeutic Effect In An Anatomical Structure - Compositions and methods of using the compositions are provided for forming an embolus within a region of an anatomical lumen for a transitory period in order to achieve a therapeutic effect. | 03-06-2014 |
| 20140072609 | BIODEGRADABLE TRIBLOCK COPOLYMERS FOR IMPLANTABLE DEVICES - The present invention is directed to polymeric materials made of biodegradable, bioabsorbable triblock copolymers and implantable devices (e.g., drug-delivery stents) containing such polymeric materials. The polymeric materials may also contain at least one therapeutic substance. The polymeric materials are formulated so as to improve the mechanical and adhesion properties, degradation, biocompatibility and drug permeability of such materials and, thus, implantable devices formed of such materials. | 03-13-2014 |
| 20140072695 | DIRECT FLUID COATING OF DRUG ELUTING BALLOON - A system and method for coating an expandable member of a medical device comprises providing a dispenser in fluid communication with a fluid source with the dispenser having at least one outlet to dispense fluid of the fluid source therefrom. The outlet(s) of the dispenser is positioned proximate a surface of an expandable member, with relative movement between the outlet(s) and the surface of the expandable member established along a coating path, and fluid is dispensed from the dispenser to form a substantially continuous bead of fluid between the at least one outlet and the surface of the expandable member along the coating path, and simultaneously drying the fluid while dispensing the fluid from the dispenser to control flow of fluid on the surface of the expandable member. The fluid source can include a variety of therapeutic agents. | 03-13-2014 |
| 20140102049 | Method Of Fabrication Of Implantable Medical Device Comprising Macrocyclic Triene Active Agent And Antioxidant - This invention relates to methods of including an oxygen-sensitive macrocyclic triene on an implantable medical device wherein the device includes separate antioxidant-containing layers above, below or both above and below the drug reservoir layer containing the macrocyclic triene. | 04-17-2014 |
| 20140134323 | METHODS OF MANUFACTURE OF BIORESORBABLE AND DURABLE STENTS WITH GROOVED LUMENAL SURFACES FOR ENHANCED RE-ENDOTHELIALIZATION - Methods of making bioabsorbable stents with grooved lumenal surfaces for enhanced re-endothelialization are disclosed. Methods include molding grooves on the lumenal surface of coated bioresorbable and durable stents. Methods further include molding grooves on lumenal surfaces of a bioresorbable tube and forming a scaffold from the tube. | 05-15-2014 |
| 20140147686 | BIOLOGICALLY ABSORBABLE COATING FOR IMPLANTABLE DEVICES BASED ON COPOLYMERS HAVING ESTER BONDS AND METHODS OF FABRICATING THE SAME - Coatings for an implantable medical device and a method of fabricating thereof are disclosed, and the coatings comprise biologically absorbable poly(ester amides). | 05-29-2014 |
| 20140147687 | BIOLOGICALLY ABSORBABLE COATING FOR IMPLANTABLE DEVICES BASED ON COPOLYMERS HAVING ESTER BONDS AND METHODS OF FABRICATING THE SAME - Coatings for an implantable medical device and a method of fabricating thereof are disclosed, and the coatings comprise biologically absorbable poly(ester amides). | 05-29-2014 |
| 20140154400 | METHOD OF DRYING BIOABSORBABLE COATING OVER STENTS - Various embodiments of methods for coating stents are described herein. Applying a composition including polymer component and solvent to a stent substrate followed by exposing the polymer component to a temperature equal to or greater than a Tg of the polymer component is disclosed. Repeating the applying and exposing one or more times to form a coating with the result that the solvent content of the coating after the final exposing step is at a level suitable for a finished stent is further disclosed. | 06-05-2014 |
| 20140161862 | ABSORBABLE COATING FOR IMPLANTABLE DEVICE - The present invention provides an absorbable coating for an implantable device and the methods of making and using the same. | 06-12-2014 |
| 20140178454 | Coating Comprising an Amorphous Primer Layer and a Semi-Crystalline Reservoir Layer - The present invention provides a coating comprising a reservoir layer comprising a semi-crystalline polymer and a primer layer comprising an amorphous polymer on an implantable device and methods of making and using the same. | 06-26-2014 |
| 20140205740 | Coated Stent and Method of Making the Same - A coated implantable medical device and a method of coating an implantable medical device is disclosed, the method includes applying a composition onto the device and drying the composition at elevated temperature in an environment having increased relative humidity. A pre-screening method for a manufacturing lot of coated stents to determine the number of drug coating layers for a desired drug release rate is disclosed. The method including coating and testing small groups of stents, and applying the results of the tests to determine the number of drug coating layers to apply to the manufacturing lot of stents. | 07-24-2014 |
| 20140206614 | Compositions for Achieving a Therapeutic Effect in an Anatomical Structure - Compositions and methods of using the compositions are provided for forming an embolus within a region of an anatomical lumen for a transitory period in order to achieve a therapeutic effect. | 07-24-2014 |
| 20140238293 | Crimping Apparatus - An apparatus is disclosed including a workspace for receiving a stent and a delivery device for the stent; a source for exposing the stent in the workspace to a plasticizing agent, vapor, or moisture, wherein the stent can be reduced in diameter in the workspace while under exposure of the plasticizing agent, vapor or moisture; and a device for reducing the diameter of the stent in the workspace to position the stent on or within the delivery device. | 08-28-2014 |
| 20140238535 | COVER SLEEVE AND APPARATUS FOR LOADING MATERIAL INTO A STENT STRUT - An apparatus for loading material into a stent strut can comprise a cover sleeve. The cover sleeve is elastic so that it can reduce in diameter so as to press against the stent strut, and expand in diameter so as to be spaced apart from the stent strut. The stent strut can include a lumen into which material is injected. When pressed against the stent strut, the cover sleeve seals side openings to the lumen and prevents injected material from leaking out of the side openings during the injection process. | 08-28-2014 |
| 20140246120 | SUCTION PUMP AND APPARATUS FOR LOADING MATERIAL INTO A STENT STRUT - An apparatus for loading material into a stent strut can comprise a suction pump connected to an opening to a lumen within the stent strut. The stent strut is immersed in the material. As the suction pump draws gas out of the lumen, the material is drawn into side openings to the lumen. | 09-04-2014 |
| 20140250836 | Method Of Fabricating An Implantable Medical Device Comprising A Rapamycin Derivative - This invention relates to an method of manufacture of an implantable medical device comprising an oxygen-sensitive rapamycin derivative that is protected by addition of an antioxidant during the manufacturing process where the amount of antioxidant added at the outset of the processing is such that when the device is fully fabricated, sterilized and packaged the amount of antioxidant has reduced to a minimal, preferably non-detect, amount. | 09-11-2014 |
| 20140255451 | Implantable Medical Device Comprising A Macrocyclic Triene Lactone Drug And Minimal Antioxidant Stabilizer And Method Of Fabrication - The present invention relates to an oxygen-sensitive macrocyclic triene lactone that is protected by addition of an appropriate amount of an antioxidant stabilizer during fabrication of an implantable medical device comprising the macrocyclic triene lactone, wherein the amount of the antioxidant stabilizer has been reduced to a minimal, preferably, non-detect, level in the final packaged product. | 09-11-2014 |
| 20140263217 | SHORT PULSE LASER MACHINING OF POLYMERS ENHANCED WITH LIGHT ABSORBERS FOR FABRICATING MEDICAL DEVICES - A method of laser machining a polymer construct to form a stent that includes a bioresorbable polymer and an absorber that increases absorption of laser energy during laser machining. The laser cuts the tubing at least in part by a multiphoton absorption mechanism and the polymer and absorber have a very low absorbance or are transparent to light at the laser wavelength. | 09-18-2014 |
| 20140276360 | ELECTROPHORECTIC DRUG COATED BALLOON AND CONDUCTIVE POLYMER COATING - Balloon catheter configured to deliver a therapeutic agent upon provision of electric potential to the balloon, the catheter comprising an electrode disposed proximate the outer surface of the expandable member, a coating disposed on at least a portion of the outer surface, the coating including a therapeutic agent; and a power source in electrical communication with the electrode is described. | 09-18-2014 |
| 20140277399 | TISSUE ADHESIVE COATINGS FOR DRUG COATED BALLOON - A therapeutic formulation is described for a drug delivery balloon comprising a therapeutic formulation which includes a therapeutic agent and an adhesion additive. The adhesion additive promotes adhesion of the therapeutic formulation a vessel wall of a subject. A system and a method of manufacturing a system including an expandable member having a working length with the therapeutic formulation disposed along at least a portion of the working length is also provided. | 09-18-2014 |
| 20140294912 | AMORPHOUS POLY(D,L-LACTIDE) COATING - Implantable devices formed of or coated with a material that includes an amorphous poly(D,L-lactide) formed of a starting material such as meso-D,L-lactide are provided. The implantable device can be used for the treatment, mitigation, prevention, or inhibition of a disorder such as atherosclerosis, thrombosis, restenosis, hemorrhage, vascular dissection or perforation, vascular aneurysm, vulnerable plaque, chronic total occlusion, patent foramen ovale, claudication, anastomotic proliferation for vein and artificial grafts, bile duct obstruction, ureter obstruction, tumor obstruction, or combinations thereof. | 10-02-2014 |
| 20140303708 | Coatings For Preventing Balloon Damage To Polymer Coated Stents - A medical assembly is disclosed comprises a stent and a catheter having a balloon, wherein the coefficient of friction and/or the adhesion at the stent/balloon interface are reduced. | 10-09-2014 |
| 20140330365 | Hollow Stent Filled With A Therapeutic Agent Formulation - A composition for loading into a structural element of a stent, where the structural element is defined by a lumen and at least one opening to access the lumen. The composition may comprise a therapeutic agent, and a chelator, a precipitation agent, or a combination thereof. Medical devices, such as stents, with a structural element defined by a lumen and at least one opening to access the lumen, filled with the compositions are also described. | 11-06-2014 |
| 20140370073 | BIOLOGICALLY DEGRADABLE COMPOSITIONS FOR MEDICAL APPLICATIONS - A medical article is disclosed, comprising a biologically degradable AB block copolymer and a biologically degradable polymer that is capable, at equilibrium and at room temperature, of absorbing less than about 5 mass % water. | 12-18-2014 |
| 20140377325 | COATINGS FOR IMPLANTABLE DEVICES COMPRISING POLYMERS OF LACTIC ACID AND METHODS FOR FABRICATING THE SAME - Coatings for an implantable medical device and a method of fabricating thereof are disclosed, the coatings comprising polymers of lactic acid. | 12-25-2014 |
| 20140377332 | NANOSHELLS ON POLYMERS - Nano-constructs comprising nanoshells and methods of using the nano-constructs for treating or ameliorating a medical condition are provided. | 12-25-2014 |
| 20140379064 | PROTECTIVE SHEATH ASSEMBLY FOR A POLYMER SCAFFOLD - A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. A sheath is placed over the crimped scaffold after crimping to reduce recoil of the crimped polymer scaffold and maintain scaffold-balloon engagement relied on to hold the scaffold to the balloon when the scaffold is being delivered to a target in a body. The sheath is removed by a health professional either by removing the sheath directly or using a tube containing the catheter. | 12-25-2014 |
| 20150018934 | POLYMERIC STENT WITH STRUCTURAL RADIOPAQUE MARKER - An implantable sent comprises a radiopaque marker that provides a structural connection between two parts made of a polymer substrate material. The two parts can be one bending element of one radially expandable ring and another bending element of an adjacent expandable ring. The two parts can be two bending elements of the same radially expandable ring. The radiopaque marker can be in the form of an entire radially expandable ring. | 01-15-2015 |
| 20150018935 | STENT WITH EASED CORNER FEATURE - An implantable stent includes a plurality of rings. At least a distal end ring has an eased corner feature formed in the polymer substrate at a radially outward, distal-facing corner of the ring while relatively sharp corners of the polymer substrate are maintained in radially inward corners of the ring. | 01-15-2015 |
| 20150030758 | METHOD FOR ELECTROSTATIC COATING OF A MEDICAL DEVICE - A method for electrostatic coating of medical devices such as stents and balloons is described. The method includes applying a composition to a polymeric component of a medical device which has little or no conductivity. The polymeric component could be a material from which the body or a strut of the stent is made or could be a polymeric coating pre-applied on the stent. The polymeric component could be the balloon wall. A charge can then be applied to the polymeric component or the polymeric component can be grounded. Charged particles of drugs, polymers, biobeneficial agents, or any combination of these can then be electrostatically deposited on the medical device or the coating on the medical device. One example of the composition is iodine, iodine, iodide, iodate, a complex or salt thereof which can also impart imaging capabilities to the medical device. | 01-29-2015 |
| 20150045877 | REGIONAL DELIVERY OF THERAPEUTIC AGENTS FOR THE TREATMENT OF VASCULAR DISEASES - The present invention relates to the regional delivery of therapeutic agents for the treatment of vascular diseases wherein regional delivery refers to delivery of a therapeutically effective amount of the therapeutic agent to an area of the vessel that includes not only afflicted tissue but non-afflicted tissue at the periphery of the afflicted tissue as well. | 02-12-2015 |
| 20150045882 | BIORESORBABLE LARYNGOTRACHEAL STENT AND METHODS OF TREATMENT - Bioresorbable stents for treating airway disorders and methods of treatment of the airway disorders using the bioresorbable stents are disclosed. Once implanted, the stents stabilize or maintain an airway lumen. The radial strength of the stents decreases with time which allows the airway to adjust from being artificially supported to a healed state without artificial support. The stent may be removed from the airway through bioresorption without intervention. The bioresorbable stents include a bioresorbable body having a shape that conforms or is conformable to the shape of the of airway lumen. | 02-12-2015 |
| 20150073535 | Treatment of coronary artery lesions with a scaffold having vessel scaffold interactions that reduce or prevent angina - Methods of treating coronary artery disease (CAD) with bioresorbable stents resulting in reduced angina or non-ischemic chest pain are described. Methods of treatment and devices for treatment of angina and post-procedural chest pain that include anti-angina agents incorporated into the device are disclosed. | 03-12-2015 |
| 20150083272 | Methods Of Loading A Hollow Stent With A Drug Or Drug Formulation - A method of loading a composition into a structural element of a stent, where the structural element is defined by a lumen and at least one opening to access the lumen. The composition may comprise a therapeutic agent, and wherein at a temperature of 30° C. and at one atmosphere, the composition may be in a solid state or semi-solid state. | 03-26-2015 |
