Steer, US
Brian Steer, San Diego, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20080233175 | Glucanases, Nucleic Acids Encoding Them And Methods For Making And Using Them - The invention relates to polypeptides having glucanase, e.g., endoglucanase, mannanase, xylanase activity or a combination of these activities, and polynucleotides encoding them. In one aspect, the glucanase activity is an endoglucanase activity (e.g., endo-1,4-beta-D-glucan 4-glucano hydrolase activity) and comprises hydrolysis of 1,4-beta-D-glycosidic linkages in cellulose, cellulose derivatives (e.g., carboxy methyl cellulose and hydroxy ethyl cellulose) lichenin, beta-1,4 bonds in mixed beta-1,3 glucans, such as cereal beta-D-glucans or xyloglucans and other plant material containing cellulosic parts. In addition, methods of designing new enzymes and methods of use thereof are also provided. In alternative aspects, the new glucanases e.g., endoglucanases, mannanases, xylanases have increased activity and stability at increased pH and temperature. | 09-25-2008 |
| 20080248160 | XYLANASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM - The invention relates to xylanases and to polynucleotides encoding the xylanases. In addition, methods of designing new xylanases and methods of use thereof are also provided. The xylanases have increased activity and stability at increased pH and temperature. | 10-09-2008 |
| 20090221051 | XYLANASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM - The invention relates to xylanases and to polynucleotides encoding the xylanases. In addition, methods of designing new xylanases and methods of use thereof are also provided. The xylanases have increased activity and stability at increased pH and temperature. | 09-03-2009 |
| 20100136113 | PHYTASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM - This invention relates to phytases, polynucleotides encoding them, uses of the polynucleotides and polypeptides of the invention, as well as the production and isolation of such polynucleotides and polypeptides. In particular, the invention provides polypeptides having phytase activity under high temperature conditions, and phytases that retain activity after exposure to high temperatures. The phytases of the invention can be thermotolerant and/or thermostable at low temperatures, in addition to higher temperatures. The phytases of the invention can be used in foodstuffs to improve the feeding value of phytate rich ingredients. The phytases of the invention can be formulated as foods or feeds or supplements for either to, e.g., aid in the digestion of phytate. The foods or feeds of the invention can be in the form of pellets, liquids, powders and the like. In one aspect, phytases of the invention are stabile against thermal denaturation during pelleting; and this decreases the cost of the phytase product while maintaining in vivo efficacy and detection of activity in feed. | 06-03-2010 |
| 20120021490 | GLUCANASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM - The invention relates to polypeptides having glucanase, e.g., endoglucanase, mannanase, xylanase activity or a combination of these activities, and polynucleotides encoding them. In one aspect, the glucanase activity is an endoglucanase activity (e.g., endo-1,4-beta-D-glucan 4-glucano hydrolase activity) and comprises hydrolysis of 1,4-beta-D-glycosidic linkages in cellulose, cellulose derivatives (e.g., carboxy methyl cellulose and hydroxy ethyl cellulose) lichenin, beta-1,4 bonds in mixed beta-1,3 glucans, such as cereal beta-D-glucans or xyloglucans and other plant material containing cellulosic parts. In addition, methods of designing new enzymes and methods of use thereof are also provided. In alternative aspects, the new glucanases e.g., endoglucanases, mannanases, xylanases have increased activity and stability at increased pH and temperature. | 01-26-2012 |
| 20130337507 | Xylanases, Nucleic Acids Encoding Them and Methods for Making and Using Them - The invention relates to xylanases and to polynucleotides encoding the xylanases. In addition, methods of designing new xylanases and methods of use thereof are also provided. The xylanases have increased activity and stability at increased pH and temperature. | 12-19-2013 |
| 20140017750 | METHODS FOR USING A THERMOSTABLE PHYTASE IN ETHANOL PRODUCTION - A method for using a thermostable phytase for eliminating or reducing phytic acid or salts of phytic acid in an alcohol production process is disclosed. The phytase can be added anywhere in the alcohol production process including a feedstock, a hammer mill, a slurry tank, a jet cooker, a liquefaction, a mash cooker, a fermentation, a beer, a distillation system, a whole stillage, a centrifuge, a thin stillage, an evaporator, a condensate, a syrup, a wet grain, a drum dryer, a distillers dried grain, distillers solubles, distillers wet grain, condensed distillers solubles distillers dried grains with solubles a molecular sieves, or any combination thereof. The alcohol production process can be in an ethanol production plant; a spirit or a drinkable alcohol production plant; or a fuel ethanol plant. | 01-16-2014 |
| 20140030779 | MICROORGANISMS AND METHODS FOR PRODUCTION OF 4-HYDROXYBUTYRATE, 1,4-BUTANEDIOL AND RELATED COMPOUNDS - The invention provides non-naturally occurring microbial organisms having a 4-hydroxybutyrate pathway and being capable of producing 4-hydroxybutyrate, wherein the microbial organism comprises one or more genetic modifications. The invention additionally provides methods of producing 4-hydroxybutyrate or related products using the microbial organisms. | 01-30-2014 |
| 20140199705 | GLUCANASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM - The invention relates to polypeptides having glucanase, e.g., endoglucanase, mannanase, xylanase activity or a combination of these activities, and polynucleotides encoding them. In one aspect, the glucanase activity is an endoglucanase activity (e.g., endo-1,4-beta-D-glucan 4-glucano hydrolase activity) and comprises hydrolysis of 1,4-beta-D-glycosidic linkages in cellulose, cellulose derivatives (e.g., carboxy methyl cellulose and hydroxy ethyl cellulose) lichenin, beta-1,4 bonds in mixed beta-1,3 glucans, such as cereal beta-D-glucans or xyloglucans and other plant material containing cellulosic parts. In addition, methods of designing new enzymes and methods of use thereof are also provided. In alternative aspects, the new glucanases e.g., endoglucanases, mannanases, xylanases have increased activity and stability at increased pH and temperature. | 07-17-2014 |
| 20140295523 | Glucanases, Nucleic Acids Encoding Them and Methods for Making and Using Them - The invention relates to polypeptides having glucanase, e.g., endoglucanase, mannanase, xylanase activity or a combination of these activities, and polynucleotides encoding them. In one aspect, the glucanase activity is an endoglucanase activity (e.g., endo-1,4-beta-D-glucan 4-glucano hydrolase activity) and comprises hydrolysis of 1,4-beta-D-glycosidic linkages in cellulose, cellulose derivatives (e.g., carboxy methyl cellulose and hydroxy ethyl cellulose) lichenin, beta-1,4 bonds in mixed beta-1,3 glucans, such as cereal beta-D-glucans or xyloglucans and other plant material containing cellulosic parts. In addition, methods of designing new enzymes and methods of use thereof are also provided. In alternative aspects, the new glucanases e.g., endoglucanases, mannanases, xylanases have increased activity and stability, including thermotolerance or thermostability, at increased or decreased pHs and temperatures. | 10-02-2014 |
| 20140371417 | MICROORGANISMS AND METHODS FOR PRODUCTION OF 4-HYDROXYBUTYRATE, 1,4-BUTANEDIOL AND RELATED COMPOUNDS - The invention provides non-naturally occurring microbial organisms having a 4-hydroxybutyrate, gamma-butyrolactone, 1,4-butanediol, 4-hydroxybutanal, 4-hydroxybutyryl-CoA and/or putrescine pathway and being capable of producing 4-hydroxybutyrate, wherein the microbial organism comprises one or more genetic modifications. The invention additionally provides methods of producing 4-hydroxybutyrate, gamma-butyrolactone, 1,4-butanediol, 4-hydroxybutanal, 4-hydroxybutyryl-CoA and/or putrescine or related products using the microbial organisms. | 12-18-2014 |
| 20150132383 | PHYTASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM - This invention relates to phytases, polynucleotides encoding them, uses of the polynucleotides and polypeptides of the invention, as well as the production and isolation of such polynucleotides and polypeptides. In particular, the invention provides polypeptides having phytase activity under high temperature conditions, and phytases that retain activity after exposure to high temperatures. The phytases of the invention can be thermotolerant and/or thermostable at low temperatures, in addition to higher temperatures. The phytases of the invention can be used in foodstuffs to improve the feeding value of phytate rich ingredients. The phytases of the invention can be formulated as foods or feeds or supplements for either to, e.g., aid in the digestion of phytate. The foods or feeds of the invention can be in the form of pellets, liquids, powders and the like. In one aspect, phytases of the invention are stabile against thermal denaturation during pelleting; and this decreases the cost of the phytase product while maintaining in vivo efficacy and detection of activity in feed. | 05-14-2015 |
| 20150148513 | MICROORGANISMS AND METHODS FOR PRODUCTION OF 4-HYDROXYBUTYRATE, 1,4-BUTANEDIOL AND RELATED COMPOUNDS - The invention provides non-naturally occurring microbial organisms having a 4-hydroxybutyrate, 1,4-butanediol, or other product pathway and being capable of producing 4-hydroxybutyrate, 1,4-butanediol, or other product, wherein the microbial organism comprises one or more genetic modifications. The invention additionally provides methods of producing 4-hydroxybutyrate, 1,4-butanediol, or other product or related products using the microbial organisms. | 05-28-2015 |
Clifford Steer, Eagan, MN US
| Patent application number | Description | Published |
|---|---|---|
| 20140296194 | PREVENTION OR ATTENUATION OF NEUROPATHIC PAIN AND KIDNEY INJURY BY TAUROURSODEOXYCHOLIC ACID - Methods of reducing or abolishing neuropathic pain in humans and animals are discussed. In some examples administration of the apoptosis inhibitor taurours-odeoxycholic acid (TUDCA), greatly reduced both neuronal loss and the increase in glia, and partially reversed spinal nerve ligation (SNL)-induced mechanical hypersensitivity. Among RVM neurons, serotonergic (5-HT) neurons decreased by 35% ipsilateral to SNL. In some examples, the density of 5-HT immunoreactive varicosities in the superficial dorsal horn of the spinal cord was lower ipsilateral to SNL. The RVM 5-HT neurons that remained after SNL appeared to facilitate nociception. When rats that had undergone SNL were treated with the 5-HT neurotoxin, 5,7-dihydroxytryptamine (5,7-DHT), mechanical withdrawal thresholds increased significantly. In some examples nerve injury induces death of antinociceptive RVM neurons which can be reduced or abolished by TUDCA. In some examples, that the loss of RVM neurons shifts the balance of descending control from pain inhibition to pain facilitation. | 10-02-2014 |
| 20150112089 | DEUTERATED BILE ACIDS - This disclosure relates to deuterated bile acid compositions. A deuterated compound is selected from the disclosed groups of bile acids and their derivatives, analogs and salts. At least one of the hydrogen atoms in the compound is replaced with deuterium. | 04-23-2015 |
Clifford J. Steer, St. Paul, MN US
| Patent application number | Description | Published |
|---|---|---|
| 20090238883 | LIVER-SPECIFIC NANOCAPSULES AND METHODS OF USING - This disclosure describes liver-specific nanocapsules for specifically targeting liver cells. This disclosure also provides methods of using such liver-specific nanocapsules to deliver one or more cargo moieties to the liver cells. | 09-24-2009 |
| 20120058180 | Liver-specific Nanocapsules and Methods of Using - This disclosure describes liver-specific nanocapsules for specifically targeting liver cells. This disclosure also provides methods of using such liver-specific nanocapsules to deliver one or more cargo moieties to the liver cells. | 03-08-2012 |
Clifford John Steer, Eagan, MN US
| Patent application number | Description | Published |
|---|---|---|
| 20140323748 | WATER-SOLUBLE URSODEOXYCHOLIC ACID PRODRUGS - Ursodeoxycholic acid (UDCA) is a bile acid with demonstrated anti-apoptotic activity in both in vitro and in vivo models. Water-soluble prodrugs of UDCA for use in indications where intravenous administration of UDCA may be preferable, such as reducing damage from stroke or acute kidney injury, are disclosed. The disclosed prodrugs showed significant anti-apoptotic activity in a series of in vitro assays. | 10-30-2014 |
David G. Steer US
| Patent application number | Description | Published |
|---|---|---|
| 20130231124 | METHOD AND SYSTEM FOR SPECTRUM SENSING AND LOW OVERHEAD FEEDBACK - A method at a network node for obtaining spectrum sensing information, the method communicating to at least one of a user equipment and a sensing node at least one event condition for spectrum sensing; providing to the at least one of the user equipment and the sensing node channel descriptors for reporting; and receiving a report from the at least one of the user equipment and the sensing node utilizing the channel descriptors, the report indicating the at least one event condition has been met. | 09-05-2013 |
Frank J. Steer, Racine, WI US
| Patent application number | Description | Published |
|---|---|---|
| 20090057331 | WIPES DISPENSER - Portable wipe dispensers are provided. In one form the wipe dispenser can be used to spray a cleaning liquid onto a wipe being dispensed from the device. Alternatively the outlet may be directed against a surface external to the dispenser. | 03-05-2009 |
Jonathan Steer, Nashua, NH US
| Patent application number | Description | Published |
|---|---|---|
| 20110292161 | Systems And Methods For Scalable Video Communication Using Multiple Cameras And Multiple Monitors - Systems and methods for performing videoconferencing using endpoints with multiple monitors and multiple cameras are disclosed herein. These endpoints are comprised of, where each node is comprised of a control unit and one or more node units, each connected to at least one monitor, camera, speaker, or microphone. Video is encoded using scalable coding, and endpoints are connected to each other over a network using an SVCS. Algorithms are described for layout management, tagging of individual streams, and use of tags for dynamic and prioritized layout management. | 12-01-2011 |
Jonathan P. Steer, Nashua, NH US
| Patent application number | Description | Published |
|---|---|---|
| 20100299385 | METHOD & APPARATUS FOR DISPLAYING THE PRESENCE OF A SHARED CLIENT COMMUNICATION DEVICE - One or more presence capable shared or non-shared client communication devices that are members of a communications group are connected to a communications network server that is capable of receiving presence information from any of the shared or non-shared client communication devices and publishing this presence information to other member of the group. The network server maintains publication instructions that are based upon a listing of the member in the group and only publishes presence information to shared and non-shared client communication devices that are members of the group. The network server also maintains permissions rules, created a primary user of a shared client communication device, that limits access by non-primary users to the shared client communication device who are member of the communications group and that controls how the presence information is displayed in a multi-level contact directory located at either a shared or non-shared client communication device. | 11-25-2010 |
| 20110289496 | METHOD & APPARATUS FOR LOAD BALANCING SOFTWARE UPDATE ACROSS A PLURALITY OF PUBLISH/SUBSCRIBE CAPABLE CLIENT DEVICES - A plurality of client communication devices, such as robotic devices, are in communication over a network with a software update service that periodically provides update software files to the client devices. The client devices register with the update service and are assigned a database queue in which an update software file is stored for the client device. Periodically, and according to a selected set of rules, the update service notifies the client devices that they can retrieve update software from a database maintained by the update service. In response to notification of the availability of a software update by the service, the client devices can send a request to the database to download the latest version of a software file. | 11-24-2011 |
K. Michael Steer, Bellevue, WA US
| Patent application number | Description | Published |
|---|---|---|
| 20130177120 | APPARATUS AND METHODS FOR CONTROLLING REACTIVITY IN A NUCLEAR FISSION REACTOR, NUCLEAR FISSION REACTORS, AND METHODS OF FABRICATING A REACTIVITY CONTROL APPARATUS - Illustrative apparatuses, assemblies, and methods for controlling reactivity in a nuclear fission reactor are disclosed, illustrative nuclear fission reactors are disclosed, and illustrative methods for fabricating a reactivity control apparatus are disclosed. | 07-11-2013 |
Marc A. Steer, San Diego, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20100197358 | SYSTEMS AND METHODS FOR VISUAL ALERTING MECHANISMS ON A MOBILE COMMUNICATION DEVICE - A mobile communication device includes an alerting mechanism comprising a light source, wherein the light source is configured to alert the user via a visual alert that an event has, or is, occurring. The event can be an incoming communication, a voice message, an alarm etc. The visual alert can be synchronized with an audible alert also included in the mobile communication device. | 08-05-2010 |
Michael Steer, Raleigh, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20150309202 | Constant Phase - Various embodiments are described that relate to a loop with a constant phase. The loop can function as an antenna and be used in object detection. A current source can be used to power the loop such that the loop produces a magnetic field and electric field. The magnetic field can be powerful enough to detect a dielectric while the electric field is so small that it does not interfere with nearby communication equipment. Thus, detection can occur without disruption of other important devices. | 10-29-2015 |
Michael Bernard Steer, Raleigh, NC US
| Patent application number | Description | Published |
|---|---|---|
| 20110210895 | MOTOR VEHICLE ANTENNA SYSTEM - A covert antenna or radio frequency probe assembly for a motor vehicle includes a substantially planar antenna or probe element including a sheet of electrically conductive material, a first dielectric substrate, and a second dielectric substrate. A connector is coupled to the antenna element and is adapted to supply electrical energy to the antenna or probe element from an electrical power source. The antenna or probe element is disposed between the first substrate and the second substrate, and the first substrate is bonded to the second substrate to form a substantially planar antenna or probe assembly. The antenna or probe assembly has the form of a motor vehicle mud guard or another substantially planar motor vehicle component. | 09-01-2011 |
Randolph C. Steer, Rancho Mirage, CA US
| Patent application number | Description | Published |
|---|---|---|
| 20110105400 | METHODS FOR TREATING ACUTE MYOCARDIAL INFARCTION - The present invention includes methods of treating acute myocardial infarction in a subject, comprising administering to the subject a therapeutically effective amount of a non-proteolytically activated thrombin receptor agonist. | 05-05-2011 |
| 20110165142 | METHOD OF TREATING DEGENERATIVE DISEASES - Agonists of a non-proteolytically activated receptor can be used in methods for treating a disease or disorder in a subject. The methods comprise administering to the subject a therapeutically effective amount of an agonist, wherein the disease or disorder is scleroderma, macular degeneration, diabetic retinopathy, Huntington's disease, Parkinson's disease, closed head trauma, glaucoma, optic neuritis or allograft vasculopathy. | 07-07-2011 |
Tom Steer, Madison, WI US
| Patent application number | Description | Published |
|---|---|---|
| 20150326020 | CONTROL OF POWER DISTRIBUTION SYSTEM - A method of controlling a plurality of outlets and a first and a second non-transitory medium for use in connection with in a power distribution. The power distribution system includes a handheld device, a power distribution device, and the plurality of outlets. The handheld device includes a first controller. The power distribution device includes a second controller and is coupled to the plurality of outlets to provide electrical power thereto. The power distribution device is physically separated from the plurality of outlets and is located not in close proximity to an outlet of the plurality of outlets. Each outlet of the plurality of outlets includes a socket and indicia located proximate to the socket. The first non-transitory medium includes instructions that when executed by the first controller cause the first controller to scan indicia of a first outlet and receive a set of input data. The first non-transitory medium also includes instructions that when executed by the first controller cause the first controller to determine and transmit a target setting of the first outlet based on the first set of input data and the scanned indicia. The second non-transitory medium includes instructions that when executed by the second controller cause the second controller to receive the target setting, and provide electrical power to the first outlet based on the target setting. | 11-12-2015 |