Patent application number | Description | Published |
20120150155 | Instrument Control Device - Embodiments include an instrument including an end effector located near a distal end of the instrument, an elongated member connected to the end effector, and a handle located near a proximal end of the instrument. The instrument also includes a ball and socket joint including a ball rotatable in a socket. The ball and socket joint connects the elongated member to the handle, and the handle is configured to move with respect to the elongated member via the ball and socket joint. The instrument further includes a control member connected to one of the ball or the socket, and the control member extends through the elongated member and connects the ball and socket joint to the end effector to control movement of the end effector. | 06-14-2012 |
20120172662 | Snare with Retractable Engaging Members - A snare for retrieving foreign objects within the body of a patient including a hollow elongate tubular member comprising an inner surface and an outer surface and a lumen defined by the inner surface, a proximal end and a distal end, the hollow elongate tubular member forms a loop at the distal end, the loop having an open position and a closed position, the loop comprising at least one opening and a wire slidably disposed in the lumen of the elongate tubular member, the wire comprising at least one engaging member for engaging tissue, the at least one engaging member extends through the at least one opening in the hollow elongate tubular member when the wire is in a first position and the at least one engaging member retracts into the lumen of the elongate tubular member when the wire moved to a in a second position. | 07-05-2012 |
20130018384 | Medical Retrieval and Capture Device and Related Methods of Use - A medical device and related methods of use are provided for capture and removal of tissue from body lumens. The device includes an end-effector unit configured to capture tissue, having a distal end and a proximal end. The distal end and the proximal end form a substantially closed structure, and the distal end is more flexible than the proximal end. The device also includes a control member at the proximal end for holding and controlling the severing device. | 01-17-2013 |
20130018385 | Polypectomy Snare Device - Medical devices are disclosed including polypectomy snare devices. An example polypectomy snare device may include an elongated sheath having a distal end. A hollow shaft may extend through and be movable relative to the sheath. A distal portion of the shaft may have a slit formed therein. The shaft may be shiftable between a first configuration wherein the distal portion is substantially straight and a second configuration wherein the distal portion includes a bend. A snare wire may be disposed within the shaft. A distal section of the snare wire may extend through the slit when the shaft is in the second configuration. | 01-17-2013 |
20130110109 | MUCOSAL RESECTION DEVICE AND RELATED METHODS OF USE | 05-02-2013 |
20130172828 | ENDOSCOPIC GUIDE WIRE TRACK - A medical device may include an end effector configured to perform a therapeutic procedure. The medical device may further include a guide having a modifiable shape. The guide may be adapted for insertion through a lumen of an access tube. Also, the end effector may be selectively attachable to the guide and configured to move along the guide. | 07-04-2013 |
20130197490 | MEDICAL DEVICE HAVING A TENSIONABLE COUPLING - This invention is directed to a medical device having an elongate shaft having a distal end and a controller coupled to the shaft. A control member can extend through at least part of the elongate shaft and at least part of the controller, wherein the control member in a tensioned configuration can be moveable by the controller to control the distal end of the shaft and the control member can be slack in an untensioned configuration. A tensioning mechanism can be configured to move relative to at least one of the elongate shaft and the controller to tension the control member and automatically lock the control member in the tensioned configuration. | 08-01-2013 |
20130197491 | MEDICAL DEVICE HAVING A MODULAR CONTROLLER - This invention is directed to a surgical instrument having an elongate shaft with a proximal and a distal end, and including a controller coupled to a proximal region of the elongate shaft. In a first configuration, the controller can control an end-effector coupled to the distal end of the elongate shaft via a control element moveably coupled to the controller. In a second configuration, the controller can move the distal end of the elongate shaft. The surgical instrument can also have an aperture configured to receive the control element in the first configuration and receive an insert element fixedly coupled to the controller and configured to cover the aperture in the second configuration. | 08-01-2013 |
20140066952 | ARTICULATION JOINT WITH BENDING MEMBER - The present disclosure provides an articulation joint that can include a plurality of articulation links, wherein each articulation link can include an elongate body having a proximal end, a distal end, an outer surface, and a first lumen extending from the proximal end to the distal end. Each articulation link can further include a plurality of arms extending radially outward from the elongate body, wherein each arm includes an inner end attached to the outer surface of the elongate body and a second lumen extending from a proximal side of the arm to a distal side of the arm. The articulation joint can also include a bending member positioned within the first lumen of the elongate body and a control member positioned within a plurality of second lumens, wherein each of the plurality of second lumens includes a common longitudinal axis. | 03-06-2014 |
20140276911 | TISSUE RESECTION SNARES - A tissue resection device for resecting tissue from a target site within a patient's body. The device includes an elongate shaft having a proximal end and a distal end. An actuation member extends partially through the shaft, and reciprocates within the shaft between a retracted position and an extended position. Multiple snare wires extend through the actuation member, and emerge outwards from a distal portion of the actuation member. The snare wires cooperate and join to form a snare loop, which engages the tissue intended to be resected. The snare loop is configured to enhance friction while engaging the tissue, to resect the tissue. | 09-18-2014 |
Patent application number | Description | Published |
20090053138 | Stabilized Aptamers to Platelet Derived Growth Factor and their Use as Oncology Therapeutics - Materials and methods are provided for producing and using aptamers as oncology therapeutics capable of binding to PDGF, PDGF isoforms, PDGF receptor, VEGF, and/or VEGF receptor or any combination thereof with affinity and specificity. The compositions of the present invention are particularly useful in solid tumor therapy and can be used alone or in combination with known cytotoxic agents for the treatment of solid tumors. Also disclosed are aptamers having one or more CpG motifs embedded therein or appended thereto. | 02-26-2009 |
20090262893 | METHODS AND APPARATUS FOR OBTAINING LOW-DOSE IMAGING - In one aspect, a method of obtaining projection data of an object from a plurality of view angles with respect to the object is provided. The method comprises acts of providing radiation, at each of the plurality of view angles, to an exposure area in which the object is positioned, controlling a radiation energy of the radiation provided at each of the plurality of view angles such that the respective radiation energy is different for at least two of the plurality of view angles, and detecting at least some of the radiation passing through the exposure area at each of the plurality of view angles to obtain the projection data. | 10-22-2009 |
20110012897 | Methods and apparatus for displaying images - In one aspect, a method of displaying data is provided. The method comprises obtaining projection data of an object by exposing an object to radiation at a plurality of view angles and detecting at least some of the radiation exiting the object to form the projection data, operating a computer to reconstruct the projection data at a reconstruction resolution to form image data comprising a plurality of voxels representing locations within the object, each of the plurality of voxels being assigned an associated intensity indicative of a density of the subject matter at the respective location, determining a maximum resolution for display, above which variation in intensity between adjacent voxels is not supported by information in the projection data, the maximum resolution being less than the reconstruction resolution, and displaying the image data at or below the maximum resolution. | 01-20-2011 |
20120219202 | METHODS AND APPARATUS FOR DISPLAYING IMAGES - In one aspect, a method of displaying data is provided. The method comprises obtaining projection data of an object by exposing an object to radiation at a plurality of view angles and detecting at least some of the radiation exiting the object to form the projection data, operating a computer to reconstruct the projection data at a reconstruction resolution to form image data comprising a plurality of voxels representing locations within the object, each of the plurality of voxels being assigned an associated intensity indicative of a density of the subject matter at the respective location, determining a maximum resolution for display, above which variation in intensity between adjacent voxels is not supported by information in the projection data, the maximum resolution being less than the reconstruction resolution, and displaying the image data at or below the maximum resolution. | 08-30-2012 |
Patent application number | Description | Published |
20090069391 | Benzothiophene hydroxamic acid derivatives - The present invention relates to a novel class of hydroxamic acid derivatives. The hydroxamic acid compounds can be used to treat cancer. The hydroxamic acid compounds can also inhibit histone deacetylase and are suitable for use in selectively inducing terminal differentiation, and arresting cell growth and/or apoptosis of neoplastic cells, thereby inhibiting proliferation of such cells. Thus, the compounds of the present invention are useful in treating a patient having a tumor characterized by proliferation of neoplastic cells. The compounds of the invention are also useful in the prevention and treatment of TRX-mediated diseases, such as autoimmune, allergic and inflammatory diseases, and in the prevention and/or treatment of diseases of the central nervous system (CNS), such as neurodegenerative diseases. The present invention further provides pharmaceutical compositions comprising the hydroxamic acid derivatives and safe dosing regimens of these pharmaceutical compositions, which are easy to follow, and which result in a therapeutically effective amount of the hydroxamic acid derivatives in vivo. | 03-12-2009 |
20100160327 | Modified Malonate Derivatives - The present invention relates to a novel class of modified malonate derivatives. The modified malonate compounds can be used to treat cancer. The modified malonate compounds can also inhibit histone deacetylase and are suitable for use in selectively inducing terminal differentiation, and arresting cell growth and/or apoptosis of neoplastic cells, thereby inhibiting proliferation of such cells. Thus, the compounds of the present invention are useful in treating a patient having a tumor characterized by proliferation of neoplastic cells. The compounds of the invention may also be useful in the prevention and treatment of TRX-mediated diseases, such as autoimmune, allergic and inflammatory diseases, and in the prevention and/or treatment of diseases of the central nervous system (CNS), such as neurodegenerative diseases. The present invention further provides pharmaceutical compositions comprising the modified malonate derivatives and safe dosing regimens of these pharmaceutical compositions, which are easy to follow, and which result in a therapeutically effective amount of the modified malonate derivatives in vivo. | 06-24-2010 |
20100240647 | Treatment of Alzheimer's Disease and Related Conditions - Compounds of formula (I) inhibit microtubule affinity regulating kinase (MARK), and hence are suitable for treating diseases associated with abnormal phosphorylation of tau. | 09-23-2010 |
Patent application number | Description | Published |
20110222667 | DRIVE SYSTEM FOR IMAGING DEVICE - A drive mechanism for a mobile imaging system comprises a main drive geared into a drive wheel for propelling the imaging system, including a base and one or more imaging components, across a surface. The drive mechanism can also include a scan drive that moves the drive mechanism and the one or more imaging components along an axis relative to the base to provide an imaging scan, and a suspension drive that extends the drive wheel relative to a bottom surface when the imaging system is in a transport mode and retracts the drive wheel relative to the bottom surface of the base when the imaging system is in an imaging mode. The drive wheel supports the weight of the imaging components, but does not directly support the base assembly, which can include pedestal and tabletop support. One or more casters located on the base can support the weight of the base assembly. | 09-15-2011 |
20110228910 | DIAGNOSTIC IMAGING APPARATUS WITH AIRFLOW COOLING SYSTEM - A diagnostic imaging system, which can be a mobile or stationary surgical CT imaging system or an MRI system, comprises an internal airflow cooling system that includes an air intake opening and an air outtake opening that are positioned near the ground and direct air flow away from the sterile surgical field. | 09-22-2011 |
20120256099 | MOBILE X-RAY IMAGING SYSTEM - A mobile diagnostic imaging system includes a battery system and charging system. The battery system is located in the rotating portion of the imaging system, and includes one or more battery packs, comprising electrochemical cells. Each battery pack includes a control circuit that controls the state of charge of each of the electrochemical cells, and implements a control scheme that causes the electrochemical cells to have a similar charge state. The battery system communicates with a charging system on the non-rotating portion to terminate charge when one or more of the electrochemical cells reach a full state of charge. The imaging system also includes a docking system that electrically connects the charging system to the battery system during charging and temporarily electrically disconnects the rotating and non-rotating portions during imaging, a drive mechanism for rotating the rotating portion relative to the non-rotating portion. | 10-11-2012 |
20130343507 | DETECTOR SYSTEM FOR IMAGING DEVICE - A detector system for an imaging system includes an airflow cooling system. The detector system includes a detector chassis, a duct extending along the length of the chassis, and a manifold that couples the duct to the interior of the chassis. A vacuum source, such as a suction fan, is coupled to the duct and generates a vacuum force within the duct. The chassis includes a plurality of inlet openings, with an airflow path being defined through the interior of the chassis between the inlet openings and the manifold. The suction fan pulls cooling air through the inlet openings, through the chassis and manifold to the duct, and then expels the air through an exhaust opening The airflow is directed into thermal contact with detector elements and associated electronics in the detector chassis to provide cooling of these components. | 12-26-2013 |
20130343509 | Multi-Plane X-Ray Imaging System and Method - Imaging systems having multiple radiation sources, such as x-ray sources, and multiple radiation detectors, such as flat-panel x-ray detectors and/or diagnostic-quality CT detectors, housed within an imaging gantry, for obtaining simultaneous images of an object positioned within a bore of the gantry in multiple imaging planes. | 12-26-2013 |
20140139215 | Vertical Scan Imaging System - An imaging system and methods including a gantry defining a bore and an imaging axis extending through the bore, and at least one support member that supports the gantry such that the imaging axis has a generally vertical orientation, where the gantry is displaceable with respect to the at least one support member in a generally vertical direction. The imaging system may be configured to obtain a vertical imaging scan (e.g., a helical x-ray CT scan), of a patient in a weight-bearing position. The gantry may be rotatable between a first position, in which the gantry is supported such that the imaging axis has a generally vertical orientation, and a second position, such that the imaging axis has a generally horizontal orientation. The gantry may be displaceable in a horizontal direction and the system may perform a horizontal scan of a patient or object positioned within the bore. | 05-22-2014 |
20140265182 | CASTER SYSTEM FOR MOBILE APPARATUS - A mobile imaging device includes a base having at least one caster, a first drive mechanism that moves the system in a transport mode and translates an imaging component relative to the base in a scan mode, and a second drive mechanism that extends caster relative to the base to raise the base off the ground in the transport mode, and retracts the caster relative to the base to lower the base to the ground in the scan mode. A caster system for a mobile apparatus includes a base containing a housing and a caster, attached to the base, the caster having a wheel defining a wheel axis and a swivel joint defining a swivel axis and a pivot point defining a pivot axis, wherein the caster pivots on the pivot axis as the caster is retracted into the housing and extended out of the housing. | 09-18-2014 |
20140275953 | MOBILE X-RAY IMAGING SYSTEM - An imaging system includes a first portion and a second portion that translates and/or rotates with respect to the first portion. A first locking mechanism may prevent the second portion from translating with respect to the first portion, such as during transport of the system. A second locking mechanism may prevent the second portion from rotating with respect to the first portion, such as during transport and/or during an imaging scan. Further embodiments include a cable management system between the first and second portions, a spherically-shaped surface of a support gimbal and a user interface device for an imaging system. | 09-18-2014 |
20140294159 | DRIVE SYSTEM FOR IMAGING DEVICE - A drive mechanism for a mobile imaging system comprises a main drive geared into a drive wheel for propelling the imaging system, including a base and one or more imaging components, across a surface. The drive mechanism can also include a scan drive that moves the drive mechanism and the one or more imaging components along an axis relative to the base to provide an imaging scan, and a suspension drive that extends the drive wheel relative to a bottom surface when the imaging system is in a transport mode and retracts the drive wheel relative to the bottom surface of the base when the imaging system is in an imaging mode. The drive wheel supports the weight of the imaging components, but does not directly support the base assembly, which can include pedestal and tabletop support. One or more casters located on the base can support the weight of the base assembly. | 10-02-2014 |
20140378817 | DIAGNOSTIC IMAGING APPARATUS WITH AIRFLOW COOLING SYSTEM - A diagnostic imaging system, which can be a mobile or stationary surgical CT imaging system or an MRI system, comprises an internal airflow cooling system that includes an air intake opening and an air outtake opening that are positioned near the ground and direct air flow away from the sterile surgical field. | 12-25-2014 |
20150374322 | DETECTOR SYSTEM FOR IMAGING DEVICE - A detector system for an imaging system includes an airflow cooling system. The detector system includes a detector chassis, a duct extending along the length of the chassis, and a manifold that couples the duct to the interior of the chassis. A vacuum source, such as a suction fan, is coupled to the duct and generates a vacuum force within the duct. The chassis includes a plurality of inlet openings, with an airflow path being defined through the interior of the chassis between the inlet openings and the manifold. The suction fan pulls cooling air through the inlet openings, through the chassis and manifold to the duct, and then expels the air through an exhaust opening. The airflow is directed into thermal contact with detector elements and associated electronics in the detector chassis to provide cooling of these components. | 12-31-2015 |