Patent application number | Description | Published |
20110196737 | SEMANTIC ADVERTISING SELECTION FROM LATERAL CONCEPTS AND TOPICS - Advertisements are selected for presentation on search result pages and web pages based on phrases generated from lateral concepts and topics identified for the search result pages and web pages. A search query or an indication of a web page is received for which advertisements are to be provided. Lateral concepts and topics are identified based on the search query or content of the web page. The lateral concepts and topics are used as phrases for selecting advertisements from an advertisement inventory. Selected advertisements are provided for presentation on a search results page in response to a search query or on a web page initially identified. | 08-11-2011 |
20110196851 | GENERATING AND PRESENTING LATERAL CONCEPTS - Systems, methods, and computer-storage media for generating lateral concepts are provided. The system includes a search engine to receive user queries, a storage to store content and its associated categories, and a lateral concept generator. The lateral concept generator is connected to both the search engine and storage. The lateral concept generator selects lateral concepts from categories associated with the content based on similarity scores for the stored content. | 08-11-2011 |
20110196875 | SEMANTIC TABLE OF CONTENTS FOR SEARCH RESULTS - A table of contents is generated for search results in response to a search query by identifying semantic concepts as topics for inclusion within the table of contents. When a search query is received, a search is performed to identify search results. The search results are compared to an ontology of topics to identify relevant topics. Additionally, search results are compared to an ontology of partial topics to identify relevant partial topics, which are named. Independent key-phrases are further generated from search results and identified as key-phrase topics. The identified topics, named partial topics, and key-phrase topics are ranked, and topics are selected for inclusion within a table of contents. A search results page is returned in response to the search query that includes search results and the generated table of contents. | 08-11-2011 |
20110218947 | ONTOLOGICAL CATEGORIZATION OF QUESTION CONCEPTS FROM DOCUMENT SUMMARIES - Electronic documents are analyzed to identify assertions, which are inverted to generate questions that may be answered by the assertions. A document or a corpus of electronic documents may be analyzed to identify entities and relationships among entities within the text of the document(s). Assertions are identified based on the entities and relationships among the entities. Each assertion represents a fact about an entity, and a group of assertions represents a summary of the document or document corpus. The assertions are inverted to generate questions that may be answered by the assertions. The questions may be further analyzed to identify relevant concepts and topics and to cluster the questions around the concepts and topics. A combined graph may also be generated that facilitates traversal among topics, concepts, questions, assertions, document summaries, and documents. | 09-08-2011 |
20110258032 | SEARCH ADVERTISEMENT SELECTION BASED ON USER ACTIONS - Advertisements are selected for presentation on a search results page based on the presence or absence of user activity within the search results page. When a search results page is provided to an end user, the search results page is tracked for user activity. If user activity is detected, a user context is identified and new advertisements are selected for presentation on the search results page based on the user context. In some embodiments, the search results page provides search results in clusters, and the user context corresponds with a search result cluster selected by an end user. In some embodiments, dominant concepts in the user context are identified and used to select advertisements. Alternatively, if user activity is not detected within a predetermined period of time, new advertisements are selected based on the absence of user activity within the search results page. | 10-20-2011 |
20110302149 | IDENTIFYING DOMINANT CONCEPTS ACROSS MULTIPLE SOURCES - Systems, methods, and computer-storage media for identifying dominant concepts are provided. The system includes a search engine connected to various sources, an entity extraction component, a metabase, and a ranking component. The search engine receives a contextual query and provides results in response to the contextual query. The entity extraction component parses the results and identifies entities included in the results. The metabase provides a distance between the entities included in the results and the query terms included in the contextual query. The ranking component ranks the entities based on the provided distance and selects dominant concepts within the results based on the ranks assigned to entities. | 12-08-2011 |
20110302156 | RE-RANKING SEARCH RESULTS BASED ON LEXICAL AND ONTOLOGICAL CONCEPTS - Search result re-ranking is provided by employing a concept graph from a metabase. When a search query is received, a query context of the search query is analyzed to identify dominant concepts for the search query. The dominant concepts are expanded by identifying the dominant concepts within a concept graph and identifying additional concepts having a strong relationship with the dominant concepts within the concept graph. A set of search results for the search query is analyzed to determine strength of relationship of each search result to the expanded concepts. The search results are re-ranked based on the strength of relationship of each search result to the expanded concepts and the strength of relationship of each expanded concept to the dominant concepts. | 12-08-2011 |
20120246155 | SEMANTIC TABLE OF CONTENTS FOR SEARCH RESULTS - A table of contents is generated for search results in response to a search query by identifying semantic concepts as topics for inclusion within the table of contents. When a search query is received, a search is performed to identify search results. The search results are compared to an ontology of topics to identify relevant topics. Additionally, search results are compared to an ontology of partial topics to identify relevant partial topics, which are named. Independent key-phrases are further generated from search results and identified as key-phrase topics. The identified topics, named partial topics, and key-phrase topics are ranked, and topics are selected for inclusion within a table of contents. A search results page is returned in response to the search query that includes search results and the generated table of contents. | 09-27-2012 |
20120303444 | SEMANTIC ADVERTISING SELECTION FROM LATERAL CONCEPTS AND TOPICS - Advertisements are selected for presentation on search result pages and web pages based on phrases generated from lateral concepts and topics identified for the search result pages and web pages. A search query or an indication of a web page is received for which advertisements are to be provided. Lateral concepts and topics are identified based on the search query or content of the web page. The lateral concepts and topics are used as phrases for selecting advertisements from an advertisement inventory. Selected advertisements are provided for presentation on a search results page in response to a search query or on a web page initially identified. | 11-29-2012 |
20140379686 | GENERATING AND PRESENTING LATERAL CONCEPTS - Systems, methods, and computer-storage media for generating lateral concepts are provided. The system includes a search engine to receive user queries, a storage to store content and its associated categories, and a lateral concept generator. The lateral concept generator is connected to both the search engine and storage. The lateral concept generator selects lateral concepts from categories associated with the content based on similarity scores for the stored content. | 12-25-2014 |
Patent application number | Description | Published |
20100104561 | TYROSINE-MODIFIED RECOMBINANT rAAV VECTOR COMPOSITIONS AND METHODS FOR USE - Disclosed are tyrosine-modified rAAV vectors, as well as infectious virions, compositions, and pharmaceutical formulations that comprise them. Also disclosed are methods of preparing and methods for using the disclosed tyrosine-phosphorylated capsid protein mutant rAAV vectors in a variety of diagnostic and therapeutic applications including in vivo and ex vivo gene therapy, and large-scale production of rAAV vectors. | 04-29-2010 |
20120004284 | PDK INHIBITOR COMPOUNDS AND METHODS OF USE THEREOF - The invention relates to methods of treating or preventing acquired or congenital mitochondrial diseases or disorders, including treating cell proliferation related disorders or diseases, such as cancer. The invention further relates to pharmaceutical compositions for treating such disorders or diseases. | 01-05-2012 |
20130203841 | Transduction Efficiency, Capsid-Modified rAAV Vectors and Methods of Use - Disclosed are tyrosine-modified rAAV vectors, as well as infectious virions, compositions, and pharmaceutical formulations that comprise them. Also disclosed are methods of preparing and methods for using the disclosed tyrosine-phosphorylated capsid protein mutant rAAV vectors in a variety of diagnostic and therapeutic applications including in vivo and ex vivo gene therapy, and large-scale production of rAAV vectors. | 08-08-2013 |
20130216501 | THERAPEUTIC METHODS BASED ON TYROSINE-SUBSTITUTED, CAPSID-MODIFIED RAAV VECTORS - Disclosed are tyrosine-modified rAAV vectors, as well as infectious virions, compositions, and pharmaceutical formulations that comprise them. Also disclosed are methods of preparing and methods for using the disclosed tyrosine-phosphorylated capsid protein mutant rAAV vectors in a variety of diagnostic and therapeutic applications including in vivo and ex vivo gene therapy, and large-scale production of rAAV vectors. | 08-22-2013 |
20130295614 | NUCLEOTIDE SEQUENCES, METHODS, KIT AND A RECOMBINANT CELL THEREOF - The present disclosure relates to recombinant adeno-associated virus (AAV) vector serotype, wherein the capsid protein of AAV serotypes is mutated at single or multiple sites. The disclosure further relates to an improved transduction efficiency of these mutant AAV serotypes. The AAV serotypes disclosed are AAV1, AAV2, AAV3, AAV4, AAV5, AAV6, AAV7, AAV8, AAV9, AAV10. The instant disclosure relates to nucleotide sequences, recombinant vector, methods and kit thereof. | 11-07-2013 |
20130310443 | AAV VECTORS WITH HIGH TRANSDUCTION EFFICIENCY AND USES THEREOF FOR GENE THERAPY - The present invention provides AAV capsid proteins comprising modification of one or a combination of the surface-exposed lysine, serine, threonine and/or tyrosine residues in the VP3 region. Also provided are rAAV virions comprising the AAV capsid proteins of the present invention, as well as nucleic acid molecules and rAAV vectors encoding the AAV capsid proteins of the present invention. Advantageously, the rAAV vectors and virions of the present invention have improved efficiency in transduction of a variety of cells, tissues and organs of interest, when compared to wild-type rAAV vectors and virions. | 11-21-2013 |
20140050701 | CAPSID-MODIFIED rAAV VECTOR COMPOSITIONS HAVING IMPROVED TRANSDUCTION EFFICIENCIES, AND METHODS OF USE - Disclosed are capsid-modified rAAV expression vectors, as well as infectious virions, compositions, and pharmaceutical formulations that include them. Also disclosed are methods of preparing and using novel capsid-protein-mutated rAAV vector constructs in a variety of diagnostic and therapeutic applications including, inter alia, as delivery agents for diagnosis, treatment, or amelioration of one or more symptoms of disease or abnormal conditions via in situ and/or ex vivo mammalian gene therapy methods. Also disclosed are large-scale production methods for capsid-modified rAAV expression vectors, viral particles, and infectious virions having improved transduction efficiencies over those of the corresponding, un-modified, rAAV vectors, as well as use of the disclosed compositions in the manufacture of medicaments for a variety of in vitro and/or in vivo applications. | 02-20-2014 |
20140341852 | CAPSID-MODIFIED RAAV VECTOR COMPOSITIONS AND METHODS THEREFOR - Disclosed are capsid-modified rAAV expression vectors, as well as infectious virions, compositions, and pharmaceutical formulations containing them. Also provided are methods of preparing and using the disclosed capsid-protein-mutated rAAV constructs in a variety of diagnostic and therapeutic modalities, including, inter alia, as mammalian cell-targeting delivery agents, and as human gene therapy vectors. Also disclosed are large-scale production methods for capsid-modified rAAV expression vectors, viral particles, and infectious virions having improved transduction efficiencies over those of the corresponding, un-modified, rAAV vectors, as well as use of the disclosed compositions in the manufacture of medicaments for a variety of in vitro and/or in vivo applications. | 11-20-2014 |
Patent application number | Description | Published |
20120116772 | Method and System for Providing Speech Therapy Outside of Clinic - A system and method for speech therapy is provided that includes a mobile device, a server and a web-client. The mobile device captures and processes voice signals analyzed locally and on the server and from which a speech therapy is coordinated and delivered. The web-client through interaction with the mobile device and through the server implements a speech therapy that can be monitored and managed thereon through specified clinical moderation. The web-client also provides an alternative method to capture and transmit voice signals to the server for analysis and from which a speech therapy is coordinated and delivered. Speech therapy management can implement therapy procedures, guidelines and one-to-one communication sessions between users and providers in a non-clinical setting in real-time or at scheduled times. Other embodiments are disclosed. | 05-10-2012 |
20120209131 | Method and System of a Cardio-acoustic Classification system for Screening, Diagnosis and Monitoring of Cardiovascular Conditions - A method and system are provided for a portable cardio-acoustic device. The device includes a display with user input, a sensor array to capture heart related vibrations from infrasound and acoustically transmitted audible sound, and a processor to extract salient features in accordance with human factor analysis, separate heart sounds as a function of sound patterns modeled from mechanical and physiological processes of the heart, classify heart sound patterns in accordance with biologically based signal processing models of the auditory cortex and cerebellum, and diagnose and monitor cardiovascular condition based on the classification of the heart sound patterns. | 08-16-2012 |
20120209132 | Method and System of an Acoustic Scene Analyzer for Body Sounds - A system and method for visualizing auditory scene analysis by way of a portable device is provided. In one embodiment, the method steps include capturing multiple sounds from a sensor array of microphones connected to the portable device, performing auditory scene analysis on detected body sounds in accordance with a psychoacoustic representation of body organ functions, and rendering to a display of the portable device a visualization of auditory scene auscultation of the body sounds, including user input functionality for separated sound source tracks, sound source identifier tracks, and sound source location trajectories. | 08-16-2012 |
Patent application number | Description | Published |
20080276317 | Detection of Multi-Step Computer Processes Such as Network Intrusions - Multi-step processes such as intrusions into computer networks are detected from individual activities or events such as communications by identifying anchor points (FIG. | 11-06-2008 |
20110218045 | PREDICTING GAME PLAYER MONETIZATION BASED ON PLAYER LOGS - A massively multiplayer online game (MMOG) monetization analysis computer system may include an electronic data processing system configured to electronically analyze data, including player behavioral logs, in accordance with one or more algorithms. Based on the analysis, the electronic data processing system may predict player changes that are relevant to monetization of the MMOG and generate a report relating to these predicted changes. The analysis may identify players whom are predicted to terminate their subscriptions to the MMOG, an amount of time each of several players is likely to spend playing the MMOG, and/or a number of transactions each of a several players is likely to engage in while playing the MMOG. | 09-08-2011 |
20120158455 | ESTIMATING VALUE OF USER'S SOCIAL INFLUENCE ON OTHER USERS OF COMPUTER NETWORK SYSTEM - The social influence that each person in a computer network system exercises over others in the system may be valued by aggregating the differences in value of each of the others to the network both with and without the person being present. This calculated influence may be used as a basis for charging advertisers for advertisements to the users, as well as for providing preferential treatment to users that exert the greatest influence. | 06-21-2012 |
20130123003 | AUTOMATIC DETECTION OF DEVIANT PLAYERS IN MASSIVELY MULTIPLAYER ONLINE ROLE PLAYING GAMES (MMOGS) - Gold farming refers to the illicit practice of gathering and selling virtual goods in online games for real money. Although around one million gold farmers engage in gold farming related activities, to date a systematic study of identifying gold farmers has not been done. Here data is used from the Massively Multiplayer Online Role Playing Game (MMOG) EverQuest II to identify gold farmers. This is posed as a binary classification problem and a set of features is identified for classification purposes. Given the cost associated with investigating gold farmers, criteria are also given for evaluating gold farming detection techniques, and suggestions provided for future testing and evaluation techniques. | 05-16-2013 |
20140057244 | Predictive Executive Functioning Models Using Interactive Tangible-Graphical Interface Devices - A method of diagnosing attention deficit hyperactivity disorder (ADHD). The method employs a tangible graphical interactive game wherein the interactive game employs a plurality of tangible graphical cubes. The game induces stimuli, measures responses and accumulates the responses using a predefined set of variables into a predefined set of metrics, wherein the variables are determined using an interactive machine learning feedback algorithm. | 02-27-2014 |
Patent application number | Description | Published |
20120189194 | MITIGATING USE OF MACHINE SOLVABLE HIPS - One or more techniques and/or systems are disclosed for mitigating machine solvable human interactive proofs (HIPs). A classifier is trained over a set of one or more training HIPs that have known characteristics for OCR solvability and HIP solving pattern from actual use. A HIP classification is determined for a HIP (such as from a HIP library used by a HIP generator) using the trained classifier. If the HIP is classified by the trained classifier as a merely human solvable classification, such that it may not be solved by a machine, the HIP can be identified for use in the HIP generation system. Otherwise, the HIP can be altered to (attempt to) be merely human solvable. | 07-26-2012 |
20120296965 | DETECTING POTENTIALLY ABUSIVE ACTION IN AN ONLINE SOCIAL NETWORK - One or more techniques and/or systems are disclosed for detecting a potentially abusive action for an online social network of a user. A network expansion profile and/or communications profile may be determined for the online social network of the user, by tracking user actions while building and/or maintaining the online social network. A reputation profile, such as a rating, for the online social network can be determined by combining information from the network expansion profile for the online social network and/or the communication profile for the online social network. Based upon the determined reputation profile, an action of the online social network, such as sending a communication, may be identified as potentially abusive and thus be treated as such (e.g., be accompanied by a warning to intended recipients that the communication may be from a spammer). | 11-22-2012 |
20120297484 | DETECTING A COMPROMISED ONLINE USER ACCOUNT - One or more techniques and/or systems are disclosed for detecting and/or mitigating a potentially compromised online user account. One or more baselines can be established for a user's online account to determine a normal usage pattern for the account by the user (e.g., frequency of incoming/outgoing emails, text messages, etc.). The online user account can be periodically or continually monitored for use of the same resources used to determine the baseline(s). If a deviation from the baseline is detected, the deviation may be compared against a threshold to determine whether the deviation indicates that the account may be compromised. When an indication of a potentially compromised account is detected, the user can be notified of the indication, so that one or more actions can be taken to mitigate the potentially compromised account. | 11-22-2012 |
Patent application number | Description | Published |
20090099939 | CONFIGURABLE INTELLIGENT COUNTDOWN CLOCK FOR ONLINE AUCTIONS - This disclosure describes, generally, methods and systems for dynamically counting down to an on-line auction end time. The method includes initiating a countdown clock with an end time that corresponds to the on-line auction end time, and accessing an auction server to obtain data used to refresh a current time of the countdown clock. The auction server is accessed at an incrementally faster refresh rate as the on-line auction end time is approached. The method further includes presenting, based on the refresh data obtained from accessing the auction server, an updated countdown clock. | 04-16-2009 |
20090198609 | FACILITATING MULTI-PHASE ELECTRONIC BID EVALUATION - A computer implemented approach to facilitate multi-phase bid evaluation. In one embodiment, a digital processing system receives information packets (corresponding to bids) from different suppliers containing information elements associated with one of a sequence of phases. On receiving an indication (from a buyer) that a specific phase of the bidding is to be evaluated starting at a time instance, the system allows the buyer access of elements associated with the specific phase only after the time instance, while allowing access to elements associated with a previous phase (occurring prior to the specific phase in the sequence of phases) even before the time instance. In a scenario where the suppliers who have successfully qualified in the previous phase are received, the system allows access of elements associated with the specific phase corresponding only to the qualified suppliers in response to the indication. | 08-06-2009 |
20130073409 | DYNAMIC AUCTION MONITOR WITH GRAPHIC INTERPRETIVE DATA CHANGE INDICATORS - A method, system, and computer program product for updating an auction monitor display with highlighting or emphasis in the form of graphic data change indicators. The method commences by capturing a first set of auction variables, the auction variables pertaining to an ecommerce auction involving a plurality of auction participants in the ecommerce auction. Then, for ongoing real-time display, the method introduces a delay of a variable duration of time, the variable duration of time based on the length of time before the end of the auction. At various points within each delay period, the method captures a second set of auction variables which are compared to the first set of auction variables to identify a candidate set of changed auction variables for emphasis. The determination of the manner of emphasis is based on the changed auction variable and characteristics of the type of change of the changed auction variable. | 03-21-2013 |
20130073518 | INTEGRATED TRANSACTIONAL AND DATA WAREHOUSE BUSINESS INTELLIGENCE ANALYSIS SOLUTION - A system, computer-implemented method, and computer program product for performing integrated transactional and data warehouse business intelligence analysis using a correlated report constructed from data correlations between current transactional data and historical data from a data warehouse. The method commences by retrieving a transactional data record from an online transactional processing (OLTP) system, the transactional data record comprising at least one OLTP business intelligence value of a particular business intelligence attribute, then receiving from a storage system, results of a query to a data warehouse, the results comprising a historical business intelligence value of the same business intelligence attribute. Modules within the system (e.g., a business intelligence application) perform processing to combine the OLTP business intelligence value with the historical business intelligence value to form a correlated report and transmit the correlated report for displaying on a single surface. | 03-21-2013 |
20130073935 | PREDICTIVE SYSTEM RECOMMENDED ACTIONS BASED ON RECENT ACTIVITIES - Embodiments of the invention provide systems and methods for tracking recent activities of processes and presenting recommended next actions based thereon. According to one embodiment, a method of tracking and interacting with one or more processes can comprise detecting one or more activities, each activity related to at least one of a plurality of ongoing transactions of the one or more processes. The one or more activities can be recorded in records of an activity log. At a later point in time, relevant records of the activity log for a particular user can be identified. A determination of a recommended next action can be made for each identified relevant record based on the recorded activity and the related transaction. A list of the identified relevant records of the activity log and the determined recommended next actions can be generated and presented to the user. | 03-21-2013 |
20140218383 | VISUAL DATA ANALYSIS FOR LARGE DATA SETS - A system and method for illustrating enterprise data. An example method includes accessing data from an enterprise application, wherein the data is organized into one or more objects; categorizing the one or more objects based on a grouping criterion, resulting in one or more groups of one or more categorized objects in response thereto; displaying representations of the one or more categorized objects as nodes of a visualization such that each node is positioned in a section of the visualization according to a group associated with the node, resulting in one or more sections of nodes corresponding to the one or more groups; and adjusting a luminance of each node based on a node-appearance criterion. The visualization may be automatically sectioned based on a select combination of user-specified data attributes or criteria, where the selected combination yields a visualization with the most dark nodes in a given section. | 08-07-2014 |
Patent application number | Description | Published |
20130066977 | MESSAGE QUEUE BEHAVIOR OPTIMIZATIONS - Network and storage calls are reduced by batching messages. Messages are collected from a client and sent to the gateway or backend application in one round trip. Alternatively, the messages are collected for different entities, and the batched messages are durably stored. Related messages, which may have the same sessionID, are grouped into a logical unit or session. This session may be locked to a single message consumer. A session may be associated with an application processing state as an atomic unit of work while other operations are performed on the messages in the session. Acknowledgements are accumulated by a broker on a message server, but the messages are not immediately deleted. Instead, multiple messages in a selected range are periodically truncated from a message store in a single operation. Expired messages for active sessions are proactive cleaned up to prevent sessions from reaching a quota or limit. | 03-14-2013 |
20130204934 | EFFICIENTLY RECEIVING MESSAGES ACROSS A LARGE NUMBER OF MESSAGING ENTITIES - A messaging service is described that facilitates the efficient receipt of messages by a client from across a large number of messaging entities hosted by different messaging hosts within a distributed messaging system. A gateway in the distributed messaging system forwards a request for an available message or set of related messages from the client to each of the messaging hosts. Each messaging host provides a response to a request if a messaging entity hosted thereby includes at least one available message or set of related messages. The messaging host manages the order in which responses from different messaging entities are provided to ensure fairness. The gateway forwards a selected one of the responses to the consumer, while caching the other responses to service future requests from the consumer. | 08-08-2013 |
20130246561 | HIGH DENSITY HOSTING FOR MESSAGING SERVICE - Aspects of the subject matter described herein relate migrating message for a messaging service. In aspects, a determination is made that messages need to be migrated based on a threshold being crossed. In response, an agent is instructed to migrate data associated with the messages to another location. The agent uses various factors to determine one or more queues to migrate. While a queue is being migrated, during a first portion of the migration, messages may be added to and removed from the queue as senders send new messages and receivers consume messages. During a second portion of the migration, the queue is frozen to disallow the queue to be used for receiving new messages and delivering queued messages. The migration may be orchestrated to attempt to achieve certain goals. | 09-19-2013 |
20130304826 | SCHEDULED MESSAGES IN A SCALABLE MESSAGING SYSTEM - Techniques are provided for scheduled and non-scheduled delivery of messages. A message directed to at least one consumer is received at a message entity. The message is determined to include a scheduled delivery time. The received message is stored in a scheduled sub-queue of the message entity. Activation metadata is retrieved and stored for any messages stored in the scheduled sub-queue that include a scheduled delivery time within a predetermined upcoming time period. If when the message is received, the scheduled delivery time of the message is within a current activation window, the activation metadata for the message may be extracted and stored immediately. The stored activation metadata is analyzed to determine a batch of messages in the scheduled sub-queue ready for delivery. The determined batch of messages is stored in an active sub-queue of the message entity, to be ready for delivery at the request of a consumer. | 11-14-2013 |
Patent application number | Description | Published |
20080235141 | License manager and schema - A license management system may have an adapter or interface that enables any type of licensed software or service to be managed through a common administrative view. The adapters may use a common schema that includes various parameters about a license as well as information that may enable a license management system to interact with a license vendor or license provider. The licenses may include locally operating software, software operating over a local area network, and various services that may be provided over a network including the Internet. The license management system may support many types of licenses and may be able to consolidate license management of many different devices and types of devices. The license management system may display the various licenses, as well as provide some other functions including alerting, usage monitoring, and managing licenses. | 09-25-2008 |
20080243699 | License optimization and automated management - A license management system may include a license analyzer that is capable of evaluating different licensing strategies for software products or services on a single device or a group of devices. Rules for licensing options are coupled with actual usage data and forecasts to determine various licensing options. The options may be implemented by an automated system for renewing licenses or changing licenses and installing updated licenses. | 10-02-2008 |
20130138813 | ROLE INSTANCE REACHABILITY IN DATA CENTER - Individual role instance reachability and load balancing are simultaneously provided for role instances of an application running in a hosting environment. Instance endpoints may be assigned to each role instance. Each instance endpoint may comprise a combination of an IP address, a transport protocol, and a unique port number. Additionally, a load balanced endpoint may be assigned to the group of role instances. The load balanced endpoint may comprise a combination of an IP address, transport protocol, and another unique port number. When application messages are issued to the data center, the messages are routed in accordance with endpoints used by the messages. For an instance endpoint, the message is routed to a role instance corresponding with the instance endpoint without load balancing. For the load balanced endpoint, the message is routed to any one of the role instances using load balancing. | 05-30-2013 |
Patent application number | Description | Published |
20090208524 | USING HEAT SHOCK PROTEINS TO IMPROVE THE THERAPEUTIC BENEFIT OF A NON-VACCINE TREATMENT MODALITY - The present invention relates to methods of improving a treatment outcome comprising administering a heat shock protein (HSP) preparation or an α-2-macroglobulin (α2M) preparation with a non-vaccine treatment modality. In particular, an HSP preparation or an α2M preparation is administered in conjunction with a non-vaccine treatment modality for the treatment of cancer or infectious diseases. In the practice of the invention, a preparation comprising HSPs such as but not limited to, hsp70, hsp90 and gp96 alone or in combination with each other, noncovalently or covalently bound to antigenic molecules or α2M, noncovalently or covalently bound to antigenic molecules is administered in conjunction with a non-vaccine treatment modality. | 08-20-2009 |
20090247456 | Complexes of alpha (2) macroglobulin and antigenic molecules for immunotherapy - The present invention relates to complexes of alpha (2) macroglobulin associated with antigenic molecules for use in immunotherapy. The invention relates to methods for using such compositions in the diagnosis and treatment of immune disorders, proliferative disorders, and infectious diseases. | 10-01-2009 |
20120021996 | USING HEAT SHOCK PROTEINS TO IMPROVE THE THERAPEUTIC BENEFIT OF A NON-VACCINE TREATMENT MODALITY - The present invention relates to methods of improving a treatment outcome comprising administering a heat shock protein (HSP) preparation or an α-2-macroglobulin (α2M) preparation with a non-vaccine treatment modality. In particular, an HSP preparation or an α2M preparation is administered in conjunction with a non-vaccine treatment modality for the treatment of cancer or infectious diseases. In the practice of the invention, a preparation comprising HSPs such as but not limited to, hsp70, hsp90 and gp96 alone or in combination with each other, noncovalently or covalently bound to antigenic molecules or α2M, noncovalently or covalently bound to antigenic molecules is administered in conjunction with a non-vaccine treatment modality. | 01-26-2012 |
20120021997 | USING HEAT SHOCK PROTEINS TO IMPROVE THE THERAPEUTIC BENEFIT OF A NON-VACCINE TREATMENT MODALITY - The present invention relates to methods of improving a treatment outcome comprising administering a heat shock protein (HSP) preparation or an α-2-macroglobulin (α2M) preparation with a non-vaccine treatment modality. In particular, an HSP preparation or an α2M preparation is administered in conjunction with a non-vaccine treatment modality for the treatment of cancer or infectious diseases. In the practice of the invention, a preparation comprising HSPs such as but not limited to, hsp70, hsp90 and gp96 alone or in combination with each other, noncovalently or covalently bound to antigenic molecules or α2M, noncovalently or covalently bound to antigenic molecules is administered in conjunction with a non-vaccine treatment modality. | 01-26-2012 |
20140107391 | USING HEAT SHOCK PROTEINS TO IMPROVE THE THERAPEUTIC BENEFIT OF A NON-VACCINE TREATMENT MODALITY - The present invention relates to methods of improving a treatment outcome comprising administering a heat shock protein (HSP) preparation or an α-2-macroglobulin (α2M) preparation with a non-vaccine treatment modality. In particular, an HSP preparation or an α2M preparation is administered in conjunction with a non-vaccine treatment modality for the treatment of cancer or infectious diseases. In the practice of the invention, a preparation comprising HSPs such as but not limited to, hsp70, hsp90 and gp96 alone or in combination with each other, noncovalently or covalently bound to antigenic molecules or α2M, noncovalently or covalently bound to antigenic molecules is administered in conjunction with a non-vaccine treatment modality. | 04-17-2014 |
Patent application number | Description | Published |
20130272269 | HANDOFFS BETWEEN ACCESS POINTS IN A WI-FI ENVIRONMENT - Techniques disclosed herein include systems and methods for providing active mobility of Wi-Fi enabled devices within a given wireless local area network (WLAN). In general, techniques include dynamically commanding Wi-Fi enabled devices to disconnect from a corresponding access point in response to meeting predetermined conditions. A forced disconnect can be based on various criteria such as low-power or lost packet thresholds triggering the forced disconnect. Such techniques cause a Wi-Fi enabled device to disconnect from one access point and connect to another access point before a connection quality deteriorates to a point that causes noticeable interruptions in connectivity or a generally poor experience, thereby enabling a smooth transition among access points. | 10-17-2013 |
20140051451 | Resource Installation Management in a Wireless Network - A graphical user interface displays a proposed site plan of one or more new base stations with respect to existing network infrastructure in a geographical region. While in the field, an installation specialist can perform an in-person survey of the geographical region to determine whether a proposed location is suitable for installation of a wireless base station. The installation specialist may identify an obstacle that would inhibit a newly proposed wireless base station from providing desired coverage if installed at the proposed location. Via input to the graphical user interface, the installation specialist proposes an alternative location in which to install the new base station. A processor performs a validity check and provides feedback indicating whether installation of the new base station at the alternative location is acceptable. The graphical user interface also can support collection of site survey data to monitor progress of the installation. | 02-20-2014 |
20140064181 | WIRELESS MESH NETWORK CONFIGURATION - A wireless mesh network employs an integrated interface between a plurality of access points for mitigating throughput degradation of multiple consecutive “daisy chain,” or mesh, links. The mesh network employs a plurality of access points, each linked back to a root access point by a series of “hops” through other access points. The wireless mesh network, therefore, employs a plurality of access points operable for wireless links to subscriber, or user, devices, including cellular phones, smart phones, tablet and laptop computing devices, or any suitable portable or handheld computing device. Access points establish an integrated interface with an adjacent access point for direct coupling of the access points for message traffic. The resulting integrated access point establishes a wireless link to a root access point connected to a backhaul network from which media services emanate. | 03-06-2014 |
Patent application number | Description | Published |
20130296694 | SURGICAL INSTRUMENTS FOR OCT ASSISTED PROCEDURES - Assemblies are provided for use as surgical instruments in optical coherence tomography (OCT) assisted surgical procedures. Each assembly includes a working assembly, formed from a material selected for desirable optical properties or modified to increase the visibility of the material in an OCT scan, and a handle attached to the working assembly. | 11-07-2013 |
20140085714 | APPARATUS FOR SELECTIVELY CONNECTING ITEMS - An apparatus for selectively connecting an accessory item to a surgical microscope includes a center pivot. An adapter arm includes an adapter support having a substantially planar support body which extends laterally in an outboard direction from the center pivot and has laterally spaced inboard and outboard support regions separated by a laterally oriented centerline. The adapter arm is configured to accept at least a portion of the accessory item in a supporting relationship. An undermount adapter includes a substantially planar undermount body having laterally spaced inboard and outboard body regions separated by a laterally oriented centerline. A plurality of microscope attachment throughholes each throughhole extend through the undermount body. Each throughhole is configured to accept a fastener for securement of the undermount adapter to the surgical microscope. An arm receiver is configured to accept the adapter tongue of the adapter arm in a supporting relationship. | 03-27-2014 |
20140119624 | VOLUMETRIC ANALYSIS OF PATHOLOGIES - Systems and methods are provided for volumetric analysis of pathologies. A segmentation component is configured to determine, for each of a series of images of a region of interest containing a pathological feature, a set of segmentation boundaries within the image representing a cross-section of the pathological feature. A mesh generation component is configured to link the sets of segmentation boundaries from adjacent images in the series of images to generate a polygonal mesh representing a volumetric reconstruction of the pathological feature. A volumetric measurement component is configured to calculate volumetric parameters from the volumetric reconstruction representing the pathological feature. A user interface is configured to provide the calculated volumetric parameters to an associated display. | 05-01-2014 |
20140221822 | INSTRUMENT DEPTH TRACKING FOR OCT-GUIDED PROCEDURES - Systems and methods are provided for tracking a depth of a surgical instrument in an optical coherence tomography (OCT) guided surgical procedure. An OCT device is configured to image a region of interest to provide OCT data. A scan processor is configured to determine a relative position of the instrument and a target within the region of interest from at least the OCT data, where the instrument is one of in front of the target, within the target, or below the target. A feedback element is configured to communicate the relative position of the instrument and the target to a user in a human comprehensible form. | 08-07-2014 |
20150055093 | MICROSCOPE-INTEGRATED OCT SYSTEM WITH AN ELECTRICALLY TUNABLE FOCUS - A surgical imaging system is provided. The surgical imaging system includes a surgical microscope and a telecentric optical coherence tomography scanning unit configured to scan a sample through at least one optical component associated with the surgical microscope. | 02-26-2015 |
Patent application number | Description | Published |
20110136737 | DPP-IV Resistant GIP Hybrid Polypeptides with Selectable Properties - The Present invention relates generally to novel GIP analogs and GIP hybrid polypeptides with selectable properties, useful as agents for the treatment and prevention of metabolic diseases and disorders, for example those which can be alleviated by control plasma glucose levels, insulin levels, and/or insulin secretion, positive inotropic effects, reduction of catabolic effects, slowing of gastric emptying. Such conditions and disorders include, but are not limited to, hypertension, dyslipidemia, cardiovascular disease, eating disorders, critical care, insulin-resistance, obesity, and diabetes mellitus of any kind, including type 1, type 2, and gestational diabetes. | 06-09-2011 |
20130281374 | DPP-IV RESISTANT GIP HYBRID POLYPEPTIDES WITH SELECTABLE PROPERTIES - The present invention relates generally to novel GIP analogs and GIP hybrid polypeptides with selectable properties, useful as agents for the treatment and prevention of metabolic diseases and disorders, for example those which can be alleviated by control plasma glucose levels, insulin levels, and/or insulin secretion, positive inotropic effects, reduction of catabolic effects, slowing of gastric emptying. Such conditions and disorders include, but are not limited to, hypertension, dyslipidemia, cardiovascular disease, eating disorders, critical care, insulin-resistance, obesity, and diabetes mellitus of any kind, including type 1, type 2, and gestational diabetes. | 10-24-2013 |