Srinivas Rao
Srinivas Rao, Columbia, MD US
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20110081377 | AEROSOLIZED GENETIC VACCINES AND METHODS OF USE - The present invention generally features methods for the mucosal delivery of immunogenic compositions and methods for treating or preventing diseases featuring such immunogenic compositions. In particular embodiments, the immunogenic compositions are genetic vaccines formulated as aerosols. | 04-07-2011 |
20110171260 | INFLUENZA DNA VACCINATION AND METHODS OF USE THEREOF - The present invention relates to an influenza immunogen that includes one or more DNA constructs encoding at least two divergent influenza HAs, wherein each of such one or more DNA constructs encodes one or more of the at least two divergent influenza HAs. Such an immunogen, when administered to a subject, induces an immune response to a plurality of strains of influenza virus, wherein at least one strain of the plurality of strains does not encode any of the divergent influenza HAs encoded by the immunogen. The divergent influenza HAs can be swine influenza HAs or equine influenza HAs, such as influenza H1 HAs or influenza H3 HAs. The invention also relates to a method to use such an immunogen to induce such an immune response as well as to DNA constructs comprising such divergent influenza HAs. Such an immunogen can provide a heterologous as well as a homologous immune response. Such an immunogen can be used to induce an immune response against evolving influenza virus. | 07-14-2011 |
20120003266 | VIRUS LIKE PARTICLE COMPOSITIONS AND METHODS OF USE - The invention features compositions and methods for the prevention or treatment of one or more strains of Chikungunya virus, as well as other alphavirus-mediated diseases. | 01-05-2012 |
20140170186 | VIRUS-LIKE PARTICLES AND METHODS OF USE - The invention features modified alphavirus or flavivirus virus-like particles (VLPs). The invention provides methods, compositions, and kits featuring the modified VLPs. The invention also features methods for enhancing production of modified VLPs for use in the prevention or treatment of alphavirus and flavivirus-mediated diseases. The invention also provides methods for delivering agents to a cell using the modified VLPs. | 06-19-2014 |
Srinivas Rao, Escinitas, CA US
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20100204205 | TOLERABILITY OF MIRTAZAPINE AND A SECOND ACTIVE AGENT BY USING THEM IN COMBINATION - A reduction in the side effects of treating with an agent having combined 5HT2/5HT3 and alpha-2 antagonistic activity is obtained by administering an agent having histamine H1 receptor agonist activity. A combined dosage form comprising an agent having 5HT2/5HT3 and alpha-2 antagonistic activity and an agent having histamine H1 receptor agonist activity is presented. Some embodiments of the combined dosage form comprise an immediate release component comprising an agent having 5HT2/5HT3 and alpha-2 antagonistic activity and a delayed release component comprising an agent having histamine H1 receptor agonist activity. Some embodiments of the combined dosage form comprise a delayed release component comprising an agent having 5HT2/5HT3 and alpha-2 antagonistic activity and an immediate release component comprising an agent having histamine H1 receptor agonist activity. Methods of treatment and kits for administration are also provided. | 08-12-2010 |
Srinivas Rao, Encinitas, CA US
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20080293820 | METHODS FOR IMPROVING PHYSICAL FUNCTION IN FIBROMYALGIA - Methods for improving physical function in fibromyalgia syndrome by administering an NSRI such as milnacipran as disclosed. | 11-27-2008 |
20090048233 | Enhancing the Tolerability of a Seratonin Antagonist and a NSRI, a SNRI or a RIMA by Using Them in Combination - Provided are combinations of pharmaceutical agents capable of eliciting a therapeutic effect. A first therapeutic agent in the combination has 5HT | 02-19-2009 |
20090270373 | TREATMENT OF DOWN SYNDROM WITH BENZODIAZEPINE RECEPTOR ANTAGONISTS - Pharmaceutical compositions and methods of treating Down Syndrome, mental retardation or both are provided. The pharmaceutical compositions comprise one or more benzodiazepine receptor antagonists, such as flumazenil. | 10-29-2009 |
20090275562 | TOLERABILITY OF MIRTAZAPINE AND A SECOND ACTIVE BY USING THEM IN COMBINATION - A reduction in the side effects of treating with an agent having combined 5HT | 11-05-2009 |
20100160294 | TOLERABILITY OF MIRTAZAPINE AND A SECOND ACTIVE BY USING THEM IN COMBINATION - A reduction in the side effects of treating with an agent having combined 5HT | 06-24-2010 |
Srinivas Rao, Oshkosh, WI US
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20100122788 | TEMPERATURE CONTROLLED MOLD - A sand based mold and method for casting a device having a cavity. The sand based mold includes a core part including grains of sand bonded with a resin, where a shape of the core part fits a shape of the cavity of the device, and a first pipe embedded into the core part and configured to allow a compressed fluid to flow through the first pipe during a solidification process of the device, the first pipe having an inlet and an outlet that exit the mold. | 05-20-2010 |
20110209842 | System and Method for Enhancing Chaplet Fusion - System and method for fusing a chaplet to a casting. The method includes placing the chaplet on an upper surface of a mold; distributing a heater around the chaplet such that the heater is not exposed to the casting; placing a core on the chaplet such that the mold and the core define a component of a machine; heating the chaplet with the heater to a predetermined temperature; and pouring the casting in the mold, around the core and the chaplet, when the chaplet is at the predetermined temperature. | 09-01-2011 |
Srinivas Rao, Saratoga, CA US
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20090079528 | Thermally enhanced magnetic transformer - A planar transformer comprises a laminate substrate having an opening with metal traces wound thereabout forming a primary and a secondary winding, a core configured to fit inside the opening to enclose the laminate substrate. At least one heat sink fin is integrally formed with the top, bottom or both sides of the core. A method of forming a planar transformer comprises laminating a substrate having an opening with metal traces wound thereabout forming a primary and a secondary winding, fitting a core inside the opening, and enclosing the laminate substrate. One of the top, bottom or both sides of the core include one or more heat sink fins. | 03-26-2009 |
Srinivas Rao, Bangalore IN
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20140022887 | METHOD FOR ZERO TRAFFIC HIT SYNCHRONIZATION SWITCHOVER IN TELECOMMUNICATION NETWORK - Embodiments of the present disclosure relate to a Zero traffic hit synchronization switch over technique in a telecommunication network. The switch over is carried out by switching input reference of the receiver from one or more master ( | 01-23-2014 |
20140035635 | APPARATUS FOR GLITCH-FREE CLOCK SWITCHING AND A METHOD THEREOF - The invention relates to an apparatus and a method for glitch-free clock switching. In one embodiment this is accomplished by a first clock source, one or more second clock source and a clock switching control device configured to synchronize the receive input clock from the first clock source and the second clock source, and output at least one of the them according to control signal selection. | 02-06-2014 |
20140044119 | METHOD AND SYSTEM FOR MULTIPLEXING LOW FREQUENCY CLOCKS TO REDUCE INTERFACE COUNT - Embodiments of the present disclosure relate to a method and system for multiplexing the low frequency signals from at least one clock transmitter to at least one clock receiver to reduce interface count. The low frequency signals are multiplexed in a CLKMUX logic using selection signals. The selection signals are generated using system frame and system clocks. The multiplexed clock is received by the CLKDEMUX logic through an interface. The interface can be backplane connectors, PCB traces and cables. The CLKDEMUX logic dc-multiplexes the received clock and transmits to the SELECT LOGIC for selecting at least one low frequency clock. The SELECT LOGIC selects at least one low frequency clock based on the signals from a processor. The jitter attenuator filters jitter in the low frequency clock and the CLOCK SINK distributes system clocks to rest of system elements. | 02-13-2014 |
20140064302 | METHOD AND SYSTEM TO ENHANCE MANAGEMENT CHANNELS - Embodiments of the disclosure relate to a method and system for enhancing management channels. The method comprises operating TDM (Time Division Multiplex) clock frequency at a predefined rate higher than operating frequency based on available management channels. Transmitting data on the management channels using the TDM slots of a TDM based controller at a higher frequency rate. | 03-06-2014 |
20140086261 | SYSTEM ARCHITECTURE AND METHOD FOR COMMUNICATION BETWEEN DEVICES OVER BACKPLANE TO REDUCE INTERFACE COUNT - The present disclosure discloses a system architecture and method for reducing pin count on a backplane connecting plurality of devices. In an embodiment, the signals from the plurality of devices are multiplexed or mapped into time slots using a MapMux device. The MapMux device then sends the multiplexed or mapped signals over backplane on TDM bus. The MapMux device at the receiving end de-multiplexes or de-maps and sends the received signals to plurality of devices for further processing. The present disclosure allows a large number of signals to be passed between the devices through a single stream. | 03-27-2014 |
Srinivas Rao, Aurora CA
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20160076279 | LATCH WITH DOUBLE PULL FOR CLOSURE PANEL - A latch described herein comprises a ratchet movable between a primary closed position, a secondary closed position and an open position. The ratchet is biased towards the open position for facilitating travel of a striker in a fishmouth of the latch to the secondary closed position. The latch includes a pawl movable between a primary locking position, a secondary locking position and an unlocking position. The pawl is biased towards the primary locking position and has a pawl locking surface for holding the ratchet in the primary closed position and the secondary closed position. The latch includes a lift lever biased towards the open position for moving the striker in the fishmouth away from the secondary closed position and towards the open position when the pawl is in the unlocking position. The striker is further from the primary position when in the open position compared to the secondary closed position. | 03-17-2016 |