Patent application number | Description | Published |
20120129853 | METHODS OF TREATMENT USING SELECTIVE BCL-2 INHIBITORS - This invention pertains to methods of treating systemic lupus erythematosus, lupus nephritis or Sjogren's Syndrome with compounds that selectively inhibit the activity of Bcl-2 anti-apoptotic proteins. Specifically, the current invention is directed to treatment with compounds that selectively inhibit the activity of Bcl-2 proteins, with a lesser affinity for inhibiting the activity of other BCL-2 family proteins, including Bcl-x | 05-24-2012 |
20130096120 | APOPTOSIS-INDUCED AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES - Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-xL proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-xL protein. | 04-18-2013 |
20130096121 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES - Disclosed are compounds which inhibit the activity of anti-apoptotic Bc1-xL proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bc1-xL protein. | 04-18-2013 |
20140275082 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES - Disclosed herein are compounds that inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases using the compounds. | 09-18-2014 |
20150150870 | METHODS OF TREATMENT USING SELECTIVE BCL-2 INHIBITORS - This invention pertains to methods of treating systemic lupus erythematosus and Sjogren's Syndrome with compounds that selectively inhibit the activity of Bcl-2 anti-apoptotic proteins. Specifically, the current invention is directed to treatment with compounds that selectively inhibit the activity of Bcl-2 proteins, with a lesser affinity for inhibiting the activity of other BCL-2 family proteins, including Bcl-x | 06-04-2015 |
20150152097 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES - Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-xL proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-xL protein. | 06-04-2015 |
Patent application number | Description | Published |
20130046640 | CENTRALIZED MANAGEMENT OF MARKETING ACTIVITIES AMONG PARTICIPANTS OF MULTIPLE CHANNEL MARKETING NETWORKS - A marketing system, also referred to as a platform, is disclosed which facilitates centralized management of marketing activities among multiple participants of multiple channel marketing networks, where the marketing activities may include determination of one or more consumers to which marketing content is to be presented and a provision of marketing content thereto. In particular, the disclosed technology platform allows members of a channel marketing network, including, for example, sponsors/OEMs, distributors, buying groups, and resellers, to link to each other to create connections that allow a secure and managed exchange of marketing content, funding and contact data, for the purpose of executing shared business processes, such as co-marketing related processes, and having access to the results thereof. An advertising platform is provided which facilitates participant discovery and channel network formation, segregates marketing activities between channel marketing networks and among the participants of a particular channel marketing network, generates and conducts marketing campaigns on behalf of participants based on internally generated and/or participant provided marketing content and directed to participant identified contacts, facilitates the funding of those marketing campaigns by one or more participants, and facilitates gathering and evaluation of the results thereof. | 02-21-2013 |
20140122237 | CENTRALIZED MANAGEMENT OF MARKETING ACTIVITIES AMONG PARTICIPANTS OF MULTIPLE CHANNEL MARKETING NETWORKS - A marketing system, also referred to as a platform, is disclosed which facilitates centralized management of marketing activities among multiple participants of multiple channel marketing networks, where the marketing activities may include determination of one or more consumers to which marketing content is to be presented and a provision of marketing content thereto. In particular, the disclosed technology platform allows members of a channel marketing network, including, for example, sponsors/OEMs, distributors, buying groups, and resellers, to link to each other to create connections that allow a secure and managed exchange of marketing content, funding and contact data, for the purpose of executing shared business processes, such as co-marketing related processes, and having access to the results thereof. An advertising platform is provided which facilitates participant discovery and channel network formation, segregates marketing activities between channel marketing networks and among the participants of a particular channel marketing network, generates and conducts marketing campaigns on behalf of participants based on internally generated and/or participant provided marketing content and directed to participant identified contacts, facilitates the funding of those marketing campaigns by one or more participants, and facilitates gathering and evaluation of the results thereof. | 05-01-2014 |
Patent application number | Description | Published |
20120014847 | MULTIPHASE CONTACT AND DISTRIBUTION APPARATUS FOR HYDROPROCESSING - Systems and apparatus for mixing, cooling, and distributing multiphase fluid mixtures within a reactor, wherein reactor internal apparatus of the present invention provides not only improved fluid mixing and distribution to each underlying catalyst bed surface, but also offers other advantages including: decreased mixing tray height; easier maintenance, assembly and disassembly; and decreased amounts of fabrication material. In an embodiment, fluid may be evenly distributed to a catalyst bed from a fluid distribution unit comprising a nozzle tray including a plurality of nozzles, wherein the nozzles include at least one liquid inlet disposed tangentially to an inner surface of the nozzle. | 01-19-2012 |
20120014849 | MULTIPHASE CONTACT AND DISTRIBUTION APPARATUS FOR HYDROPROCESSING - Systems and apparatus for mixing, cooling, and distributing multiphase fluid mixtures within a reactor, wherein reactor internal apparatus of the present invention provides not only improved fluid mixing and distribution to each underlying catalyst bed surface, but also offers other advantages including: decreased mixing tray height; easier maintenance, assembly and disassembly; and decreased amounts of fabrication material. In an embodiment, fluid may be evenly distributed to a catalyst bed from a fluid distribution unit comprising a nozzle tray including a plurality of nozzles, wherein the nozzles include at least one liquid inlet disposed tangentially to an inner surface of the nozzle. | 01-19-2012 |