Sorenson, MN
Brent R. Sorenson, Minneapolis, MN US
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20150344537 | Non-Transgene Transfection for Therapeutic Purposes - This disclosure describes compositions and methods involved in tumor suppression and inhibiting infection of cells by pathogens. Generally, the compositions include an mRNA cargo that can provide a therapeutic benefit after being introduced into an epithelial cell. In some cases, the mRNA can encode a polypeptide. In some cases, the polypeptide can suppress epithelial cell proliferation. In other embodiments, the polypeptide can be involved in innate immunity. In various embodiments, the polypeptide can include cathelicin antimicrobial protein (CAMP), calprotectin, S100A8, S100A9, a β-defensin, S100A7, secretory leukocyte inhibitor, lipocalin 2, or lysozyme. In some embodiments, the mRNA can include a stabilizing moiety such as, for example, a 5′ cap or a 3′ extension. | 12-03-2015 |
Brent R. Sorenson, Maplewood, MN US
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20150344537 | Non-Transgene Transfection for Therapeutic Purposes - This disclosure describes compositions and methods involved in tumor suppression and inhibiting infection of cells by pathogens. Generally, the compositions include an mRNA cargo that can provide a therapeutic benefit after being introduced into an epithelial cell. In some cases, the mRNA can encode a polypeptide. In some cases, the polypeptide can suppress epithelial cell proliferation. In other embodiments, the polypeptide can be involved in innate immunity. In various embodiments, the polypeptide can include cathelicin antimicrobial protein (CAMP), calprotectin, S100A8, S100A9, a β-defensin, S100A7, secretory leukocyte inhibitor, lipocalin 2, or lysozyme. In some embodiments, the mRNA can include a stabilizing moiety such as, for example, a 5′ cap or a 3′ extension. | 12-03-2015 |
Brent Wayne Sorenson, Prior Lake, MN US
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20150348187 | SYSTEMS AND METHODS FOR DETERMINING OCCUPANCY - Certain implementations may include systems and methods for determining occupancy. According to an example implementation, a method is provided. The method includes receiving identifying information related to occupancy of a target property by a subject. The identifying information may include a name of the subject and an address of the target property. In certain embodiments, the identifying information may include an actual or approximate investigation date to allow a historical evaluation of occupancy at a specific time in the past. The method includes querying one or more public or private databases with the identifying information and receiving, in response to the querying, subject and property information. The method includes determining one or more indicators of occupancy of the target property. The method includes determining, with the one or more computer processors, a score based on the one or more indicators of occupancy; and outputting an indication of the score. | 12-03-2015 |
Brian Sorenson, New Brighton, MN US
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20100076525 | AUTOMATIC VALIDATION TECHNIQUES FOR VALIDATING OPERATION OF MEDICAL DEVICES - Techniques for validating operation of a medical device are disclosed. A data collection phase utilizes a first sensor carried by a patient to record patient parameter values indicative of conditions experienced by the patient (e.g, posture states.) Therapy parameter values describing therapy adjustments requested by the patient in response to the conditions are also recorded. Associations formed between the therapy parameter values and the patient parameter values are used to develop a closed-loop algorithm for control of an IMD having a sensor similar to the first sensor. An automated device such as a robotic arm uses the recorded patient parameter values to automatically reproduce, and to subject the IMD to, conditions present during the data collection phase. Therapy delivered by the IMD while under control of the closed-loop algorithm and while being subjected to the conditions is compared to the recorded therapy parameter values e to validate IMD operation. | 03-25-2010 |
Bryant Sorenson, Eden Prairie, MN US
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20140177886 | METHOD AND APPARATUS FOR HEARING AID LOCATION - A hearing aid includes electronics, a physically manipulable member, and a receiver. The receiver is configured to output sound in a first mode at a first decibel level and in a second mode at a second decibel level higher than the first decibel level. The first mode is based on an input from a microphone. The second mode is based on the physically manipulable member not having been manipulated over a selected period of time. In various examples, wireless approaches are used to perform location identification. Examples using antennas and radio frequency identification (RFID) are provided. Various location approaches are possible using different location tones and methods for generation of such tones. Other apparatus are provided for location identification in a system with one or more hearing aids. | 06-26-2014 |
Derek Sorenson, Erskine, MN US
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20130319785 | Off-Highway Recreational Vehicle - A recreational off-highway vehicle includes side-by-side passenger and driver seats held within a chassis that is approximately 50 inches wide. The seats sit low in the chassis and are covered by a roll cage. Grab handles are positioned on the sides of the passenger seat. Select large round tubing protects the vehicle, while rectangular tubing frames the portions of the vehicle beneath body panels. The vehicle is powered by an engine rearward of the seats that is connected to a transaxle. The engine and transaxle are isolation mounted together with a portion of the air intake assembly. The vehicle is suited for rough terrain travel. | 12-05-2013 |
Ellen L. Sorenson, Mounds View, MN US
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20130246347 | DATABASE FILE GROUPS - Files may be assigned to groups for processing in an efficient manner. For example, a group may include a list of file names for processing together. The file names are assigned to the group by a user. When a command is executed on the system for modifying a file, the group name is provided along with the command rather than the file name or list of individual file names. The command automatically executes repeatedly for each file name associated with the group name. | 09-19-2013 |
20130246363 | IDLE POINT AUDITING FOR DATABASES - Idle points for a database, such as a database management system or a relational database management system (RDMS), may be marked in an audit log of a backup device coupled to the database. The backup device may receive an indication that the database has reached an idle point and verify the idle point through a data control system coupled to the database and the backup device. Once the idle point is verified, the idle point is logged in the audit log along with the date and time of the idle point. The idle point information may be used during recovery of the database from the backup device. | 09-19-2013 |
20130246700 | DEVICE TYPE OVERRIDE - A backup system override may be specified to allow a backup system to access a backup created on an old storage device. For example, an archival backup may be accessed long after the storage device that created the backup has been decommissioned. The file history information in the backup may specify a storage device no longer accessible by the backup system. An override in the backup system allows the backup system to access the backup with the file history information through a different storage device than the storage device that created the backup. The different storage device may have a different name and/or be of a different type than the original storage device that created the backup. The override may also allow access to command scripts and links in the backup. | 09-19-2013 |
20130262388 | DATABASE BACKUP TO HIGHEST-USED PAGE - Database backup performance may be improved by copying only used portions of a database file. When the database file includes allocated but un-used pages, the unused pages are not replicated during a database backup. By replicating only the allocated and used pages in the database, the backup time may be decreased and the amount of storage required in the second file may be decreased. | 10-03-2013 |
Ellen L. Sorenson, Roseville, MN US
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20140250085 | ROLLBACK COUNTERS FOR STEP RECORDS OF A DATABASE - A rollback record may be created for each step identifier (ID). The rollback record indicates how many times the step record identified by the step ID has been rolled back during operation of the database. The rollback record may be stored in a periodic save record (PSR), separate from or stored in an audit trail containing the step records. By processing the rollback records in the periodic save record during a recovery, a database may identify a time on an audit trail for initiating a recovery prior to the last resume point for a step without going back in the audit trail to a time before the initial start of the step. | 09-04-2014 |
20140250094 | STEP IDENTIFIER BASED ON A UNIVERSAL TIMESTAMP - One or more transactions, and their audited update actions, operating on a database may be identified by a step ID. The step ID may include a first set of bits identifying a time the step was created. The step ID may also include a second set of bits uniquely identifying a step created at a certain time from other step created at the same time. The first set of bits may be generated from a coordinated universal time (UTC) that does not change with local seasons, such as daylight saving time. | 09-04-2014 |
20140324780 | DATABASE COPY TO MASS STORAGE - Databases may be copied to a shadow database on amass storage device. The structure of the files containing the database, such as blocking information and a dump history, may be copied in whole to the mass storage device. The method may include creating a shadow database on a mass storage device, populating the shadow database with data from a production database, idling an application accessing the production database to create an idle point in the production database, and updating the shadow database to the production database. | 10-30-2014 |
20140324781 | INPUT/OUTPUT (I/O) PROCEDURE FOR DATABASE BACKUP TO MASS STORAGE - Databases may be backed up on a mass storage device. Storing the database backup on mass storage, rather than tape drive, allows operations, such as from a database manager, with large input/output to improve performance. A method of backing up a database to a mass storage device may include receiving, at a database manager, a call from a backup utility to copy data from a source file to a destination file, performing, at the database manager, a plurality of input/output requests, in response to the call, to copy data from the source file to the destination file, and returning, to the backup utility, status information regarding completion of the call Placing the database backup on mass storage can further enable use of that backup as a shadow or alternate database. | 10-30-2014 |
Joseph A. Sorenson, Coon Rapids, MN US
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20090251529 | NETWORK MANAGEMENT SERVER FOR MANAGING MULTIPLE OPERATING MODES OF A CONFERENCING NETWORK WITH DIFFERENT SETS OF POLICIES - A method, system, and computer program product are disclosed to manage multiple operating modes in a video conferencing network under which different sets of policies can operate. The system is a network management server, designated herein as the Elastic Gatekeeper, that includes a Conference Management System, which selectively implements one or more different sets of operating policies. The Conference Management System is integrated and linked with a gatekeeper, which is responsible for setting up calls that are using end point alias addresses. The gatekeeper works with the Conference Management System to control access to network resources. Upon receiving a request to access a call, the gatekeeper passes the request to the Conference Management System for its approval. The Conference Management System has access to a robust set of policies, a detailed description of the network resources, and an awareness of the current System Operational Mode upon which to base a decision about the conditions and resources that can be granted to the requested call. | 10-08-2009 |
Larry Sorenson, New Prague, MN US
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20090100674 | Cable splint - A device used to secure a section of cable while one or more fiber is broken out from the cable. The device includes spaced apart clamp assemblies that hold a cable during the splicing process to protect the fairly delicate fibers within the sheathing. The disclosure also relates to a method of splicing using a clamp assembly. | 04-23-2009 |
20110154643 | CABLE SPLINT - A device used to secure a section of cable while one or more fiber is broken out from the cable. The device includes spaced apart clamp assemblies that hold a cable during the splicing process to protect the fairly delicate fibers within the sheathing. The disclosure also relates to a method of splicing using a clamp assembly. | 06-30-2011 |
Ronald Sorenson, Blaine, MN US
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20130159267 | PROVIDING COMBUSTION SYSTEM MANAGEMENT INFORMATION - The present disclosure provides methods, devices, and computer readable media for providing combustion system management information. One or more embodiments include receiving a prompt to access management information associated with a combustion system, accessing the management information associated with the combustion system in response to the prompt, and communicating the management information associated with the combustion system. | 06-20-2013 |
Scott G. Sorenson, Lakeville, MN US
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20130100551 | METHOD AND APPARATUS FOR REFLECTION CANCELLATION - A method for calibrating a reflection compensator is provided. A delay is initially set to a predetermined minimum, and an input pulse is transmitted across a transmission line. A compensation current is then applied after the delay. The reflection from the transmission line is digitized to generate a measurement, and a determination is made as to whether the compensation current substantially compensates for the reflection. If the compensation current does not substantially compensate for the reflection, then the delay is adjusted, and the process is repeated until the compensation current substantially compensates for the reflection. | 04-25-2013 |
Scott Gary Sorenson, Lakeville, MN US
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20080239543 | METHODS AND APPARATUS FOR GENERATING A HARD DRIVE WRITE SIGNAL - Methods and apparatus for generating a hard drive write signal are here in disclosed. A disclosed method comprises generating a hard drive write signal on an output of a switch based on an edge of the first control signal and reducing the hard drive write signal based on an edge of a second control signal via a second switch. | 10-02-2008 |
20080265950 | LOW-POWER IMPEDANCE-MATCHED DRIVER - One embodiment of the invention includes a driver circuit. The driver circuit comprises a high-side switch that is activated in response to a positive driver input signal to provide a positive output signal at a driver output. The driver circuit also comprises a low-side switch that is activated in response to a negative driver input signal to provide a negative output signal at the driver output. The positive and negative driver input and output signals can be relative to respective cross-over magnitudes. The driver circuit further comprises at least one impedance-matching device configured to activate the low-side switch in response to a positive signal reflection at the driver output and to activate the high-side switch in response to a negative signal reflection at the driver output. | 10-30-2008 |
Shawn Sorenson, Maple Grove, MN US
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20090118820 | DEFORMABLE UNDERLAYER FOR STENT - An endoprosthesis includes a brittle layer, e.g. a ceramic and an underlayer to accommodate dimensional changes as the endoprosthesis is flexed. | 05-07-2009 |
20090192593 | Stent for Delivery a Therapeutic Agent from a Side Surface of a Stent StSrut - Described herein are implantable medical devices, such as implantable or intravascular stents, for delivering a therapeutic agent, and methods for making such medical devices. In one embodiment, the medical device comprises a stent having a plurality of struts, at least one of which has a cavity disposed therein. A therapeutic agent is delivered from the cavity through and opening in a strut surface. In another embodiment, the medical device is a stent having a coating disposed on the side surface(s) of at least one strut for deliver of a therapeutic agent from the coating. | 07-30-2009 |
20090240322 | Bifurcation Stent Pattern - A stent may comprise a plurality of serpentine bands connected by connector struts. The stent may further comprise a side branch cell having a plurality of outwardly deployable petals. Each serpentine band may have an approximate longitudinal axis. A portion of the serpentine bands may be flared in the unexpanded state, wherein a portion of the axis of each flared band is oriented helically about a portion of the stent. The bands may reorient during stent expansion, whereafter the axis of each band is oriented in a circumferential direction. | 09-24-2009 |
20100137977 | Coating for Medical Device Having Increased Surface Area - Described herein are implantable medical devices for delivering a therapeutic agent to the body tissue of a patient, and methods for making such medical devices. In particular, the implantable medical devices, such as intravascular stents, have a coating which includes at least one coating composition and has an exposed abluminal surface and an exposed luminal surface or exposed side surface. | 06-03-2010 |