Shizuya
Hiroaki Shizuya, South Pasadena, CA US
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20110119779 | METHODS FOR SEQUENTIAL REPLACEMENT OF TARGETED REGION BY HOMOLOGOUS RECOMBINATION - The invention provides methods and compositions for generating non-human transgenic cells and organisms that are transgenic at one or more gene sequences by separately recombining fragments of a complete gene in temporal sequence. According to the methods of the invention, a set of DNA constructs containing a non-endogenous DNA sequence flanked and/or operably linked at its ends by sequences from the non-human organism are generated by recombination in a bacterial cell, for example, in | 05-19-2011 |
20110123527 | METHOD OF GENERATING SINGLE VL DOMAIN ANTIBODIES IN TRANSGENIC ANIMALS - The present invention describes methods of generating single VL domain antibodies, including chimeric single chain antibodies that comprise of a variable region of a human immunoglobulin κ or λ light chain and a non-human constant region. The non-human constant region is devoid of a first constant domain CH1, and the variable region is devoid of a heavy chain variable domain. | 05-26-2011 |
20110236378 | NON-HUMAN MAMMALS FOR THE PRODUCTION OF CHIMERIC ANTIBODIES - The invention provides knock-in non-human cells and mammals having a genome encoding chimeric antibodies and methods of producing knock-in cells and mammals. Certain aspects of the invention include chimeric antibodies, humanized antibodies, pharmaceutical compositions and kits. Certain aspects of the invention also relate to diagnostic and treatment methods using the antibodies of the invention. | 09-29-2011 |
20130167256 | GENETIC ENGINEERING OF NON-HUMAN ANIMALS FOR THE PRODUCTION OF CHIMERIC ANTIBODIES - The invention provides non-human cells and mammals having a genome encoding chimeric antibodies and methods of producing transgenic cells and mammals. Certain aspects of the invention include chimeric antibodies, humanized antibodies, pharmaceutical compositions and kits. Certain aspects of the invention also relate to diagnostic and treatment methods using the antibodies of the invention. | 06-27-2013 |
Hiroki Shizuya, Sendai JP
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20110265180 | TAMPERING MONITORING SYSTEM, MANAGEMENT APPARATUS, AND MANAGEMENT METHOD - An information security apparatus ( | 10-27-2011 |
Ken Shizuya, Tokyo JP
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20160061098 | UNIFLOW SCAVENGING 2-CYCLE ENGINE - A uniflow scavenging 2-cycle engine includes a cylinder inside in which a combustion chamber is formed; a piston which slides within the cylinder; a scavenge port which is provided on one end side in a stroke direction of the piston in the cylinder to suck an active gas into the combustion chamber in accordance with the sliding movement of the piston; and an injection unit which injects a fuel gas into the active gas suctioned to the scavenge port and is provided on an inner circumferential surface of the scavenge port or on the outside of the cylinder rather than the inner circumferential surface. Further, the amount of the fuel gas injected by the injection unit on the other end side in the stroke direction is larger than the amount of fuel gas injected by the injection unit on one end side in the stroke direction. | 03-03-2016 |
20160061099 | UNIFLOW SCAVENGING 2-CYCLE ENGINE - A uniflow scavenging two-cycle engine includes a scavenge port and a plurality of injection units which inject a fuel gas into the active gas sucked into the scavenge port and have different positions of the piston in the stroke direction. The plurality of injection units are divided into at least two sets of injection unit groups include first and second injection unit groups, the first injection unit group being a set of one or a plurality of injection units located on the other end side in the stroke direction, and the second injection unit group being a set of one or a plurality of injection units located on one end side in the stroke direction, and the injection stop of the fuel gas is later in the injection unit of the first injection unit group than in the injection unit of the second injection unit group. | 03-03-2016 |
Osamu Shizuya, Osaka JP
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20110133764 | APPARATUS AND METHOD FOR DETECTING ABNORMALITY IN SOLAR CELL POWER GENERATION SYSTEM - The present invention provides an apparatus for easily detecting an abnormal status of power generation of a solar cell panel in a solar cell power generation system having the power generation of 1 MW or higher. | 06-09-2011 |
20120268158 | FAILURE DETECTING METHOD FOR A SOLAR POWER GENERATION SYSTEM - The present invention discloses a failure detecting method for a solar power generation system having plural solar cell strings in each of which plural solar cell modules are connected to each other in series. In this method, made is a measurement of the current value of each of the solar cell modules or the current value of each of the solar cell strings and the total current value of the whole of the solar power generation system; the measured current value of each of the solar cell modules or the measured current value of each of the solar cell strings is compared with an average current value per one solar cell module or an average current value per one solar cell string that are calculated out from the measured total current value of the whole of the solar power generation system; when the measured current value(s) of one or more of the solar cell modules or the measured current value(s) of one or more of the solar cell strings is/are (each) lower than the calculated average current value per one solar cell module or the calculated average current value per one solar cell string by a predetermined percentage or more, the solar cell module(s) or the solar cell string(s) in the low current value state is/are extracted as failure candidate(s); and then the extracted module(s) or string(s) is/are displayed or notified. | 10-25-2012 |
20130099760 | DIRECT-CURRENT STABILIZED POWER SUPPLY DEVICE - A direct-current stabilized power supply device that drops a voltage from a power supply of a solar cell in which output power is unstable, and supplies a stable voltage necessary for measurement equipment and the like. | 04-25-2013 |