Shimizu, Shizuoka
Chikako Shimizu, Shizuoka JP
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20100093658 | Therapeutic Agent For Metabolic Syndrome and Food Containing the Therapeutic Agent - It is an object of the invention to provide a novel therapeutic agent that can reduce visceral fat accumulation to prevent or treat metabolic syndrome. In order to achieve this object, the invention provides a therapeutic agent for metabolic syndrome that comprises, as an active ingredient, dietary fiber aggregation in which water-soluble β-glucan has the highest content. Particularly effective as the water-soluble β-glucan is water-soluble β-glucan having a β-1,3 glycoside bond and β-1,4 glycoside bond in the same molecule. | 04-15-2010 |
Hidehiko Shimizu, Shizuoka JP
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20080265901 | Voltage measuring device - A pair of measuring switches S | 10-30-2008 |
20130328568 | VOLTAGE DETECTION APPARATUS AND METHOD OF REDUCING DISPERSION OF DARK CURRENTS - A voltage detection apparatus includes a plurality of voltage detection units, each of which detects cell voltages of plural cells in each of blocks in a battery module. Each of blocks includes the plural cells connected in series. The plurality of voltage detection units are respectively supplied with power via power supply lines connected to the blocks. The plurality of voltage detection units are respectively provided with a plurality of current increase units for increasing dark currents so that the dark currents flowing through the power supply lines respectively become a same target value. | 12-12-2013 |
Isanori Shimizu, Shizuoka JP
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20130075131 | SUPPORT STRUCTURE FOR BOSS - There is provided a support structure for a boss of a resin molded product. A plurality of cylindrical bosses stands up from one surface of a base plate to support a component. A plurality of reinforcing ribs extends radially from an outer circumferential surface of at least one of the bosses. The reinforcing ribs are arranged so as to be spaced apart from each other at a regular interval in a circumferential direction of the at least one of the bosses. Building-up portions are formed only on corner portions in which the outer circumferential surface of the at least one of the bosses and the reinforcing ribs intersect with each other. | 03-28-2013 |
Kaoru Shimizu, Shizuoka JP
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20100179505 | MULTI-CHAMBER CONTAINER - A multi-chamber container having an outlet port, which is usually closed and is opened in cooperation with an expanded deformation of the bag upon the opening of the medical bag and aiming to obtain more reliable opening of the medical bag upon the separation of the partition wall. The outlet port firmly welded to a strong seal | 07-15-2010 |
20100185171 | PROCESS OF FUSION-BONDING PLASTIC FILM AND DRUG BAG - The present invention relates to a process of fusion-bonding a plastic film ( | 07-22-2010 |
Kazuki Shimizu, Shizuoka JP
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20090137609 | VITAMIN D-LIKE COMPOUND - The present invention provides a compound represented by the following general formula (I): | 05-28-2009 |
20110060146 | VITAMIN-D-LIKE COMPOUNDS - The present invention provides a compound represented by the following general formula (I): | 03-10-2011 |
Kentaro Shimizu, Shizuoka JP
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20120004319 | PROCESS FOR PRODUCING CAROTENOID - The present invention provides a method for producing a carotenoid-containing composition, comprising the steps of: subjecting a culture of a carotenoid-producing microorganism to an extraction treatment using a water-soluble organic solvent; dispersing the resulting extract solution in water for micellization; heat stirring the resulting micellized solution in a solvent break the micelles and precipitate the carotenoid component of interest to obtain the precipitate; collecting and heat washing the precipitate with ethanol; and further subjecting the precipitate to pulverization/drying; and food, a pharmaceutical composition and a cosmetic product comprising the carotenoid-containing composition. | 01-05-2012 |
Masafumi Shimizu, Shizuoka JP
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20090038432 | Straddle Type Vehicle - A vehicle includes a handlebar and a handlebar cover. The handlebar cover includes a front cover for covering a front side of the handlebar and a rear cover for covering a rear side of the handlebar. The front and rear covers are fastened to each other by a fastener member. The fastener member is covered by a cover attached to the handlebar cover. | 02-12-2009 |
Masaru Shimizu, Shizuoka JP
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20110172153 | SCREENING METHODS USING G-PROTEIN COUPLED RECEPTORS AND RELATED COMPOSITIONS - The present invention provides screening methods for GPCRs based on the discovery that the affinity of a receptor agonist for a GPCR (such as the parathyroid hormone receptor) when not bound to a G-protein is correlated with the length of time over which the agonist is effective, independently of its pharmacokinetic properties. The invention also provides PTH- and PTHrP-derived polypeptides. | 07-14-2011 |
20130244508 | TERMINAL CONNECTION STRUCTURE - A terminal connection structure comprises a first terminal made in a plate shape and formed with a through-opening, a supporting section supporting the first terminal, a second terminal made in a plate shape and to be a connection counterpart of the first terminal, and a clip made of a plate-like material having an electrical conductivity, and having a central piece formed into a U-shape and opposed pieces continued from the central piece, the central piece being provided with a pair of projection portions projected from both side portions of the central piece to prevent the clip from excessively entering into the through-opening. The first terminal is interposed between the opposed pieces facing to each other with the central piece inserted into the through-opening, and the second terminal is inserted between a surface of the first terminal facing the pair of projection portions and the clip. | 09-19-2013 |
20130316584 | BUS BAR FOR FORMING FUSIBLE LINK BLOCK CIRCUIT, FUSIBLE LINK BLOCK, AND METHOD FOR MANUFACTURING FUSIBLE LINK BLOCK | 11-28-2013 |
20140086842 | SCREENING METHODS USING G-PROTEIN COUPLED RECEPTORS AND RELATED COMPOSITIONS - The present invention provides screening methods for GPCRs based on the discovery that the affinity of a receptor agonist for a GPCR (such as the parathyroid hormone receptor) when not bound to a G-protein is correlated with the length of time over which the agonist is effective, independently of its pharmacokinetic properties. The invention also provides PTH- and PTHrP-derived polypeptides. | 03-27-2014 |
20140183310 | STRUCTURE FOR FIXING ELECTRICAL JUNCTION BOX - A structure for fixing an electrical junction box is provided which makes it possible to fix the same electrical junction box, irrespective of the sizes, shapes and the like of batteries, and to commonly use the electrical junction box. The structure includes a bracket including a junction box fixing part which fixes the electrical junction box and a battery fixing part which is fixed to the battery. The electrical junction box is fixed to the battery via the bracket. | 07-03-2014 |
Naoto Shimizu, Shizuoka JP
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20090264365 | CONFORMATIONALLY CONSTRAINED PARATHYROID HORMONE (PTH) ANALOGS - The present invention relates to conformationally constrained parathyroid hormone (PTH) analogs, and methods of preparing and using the PTH analogs. The invention provides novel PTH polypeptide derivatives containing amino acid substitutions at selected positions in the polypeptides. The invention provides derivatives of PTH(1-34), PTH(1-21), PTH(1-20), PTH(1-19), PTH(1-18), PTH(1-17), PTH(1-16), PTH(1-15), PTH(1-14), PTH(1-13), PTH(1-12), PTH(1-11), and PTH(1-10) polypeptides, wherein at least one residue in each polypeptide is a helix, preferably an α-helix, stabilizing residue. The invention also provides methods of making such peptides. Further, the invention encompasses compositions and methods for use in limiting undesired bone loss in a vertebrate at risk of such bone loss, in treating conditions that are characterized by undesired bone loss or by the need for bone growth, e.g., in treating fractures or cartilage disorders and for raising cAMP levels in cells where deemed necessary. | 10-22-2009 |
Shun Shimizu, Shizuoka JP
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20140234340 | ANTIGEN-BINDING MOLECULE CAPABLE OF BINDING TO PLURALITY OF ANTIGEN MOLECULES REPEATEDLY - An objective of the present invention is to provide methods for promoting antigen uptake into cells by antigen-binding molecules, methods for increasing the number of times of antigen binding by one antigen-binding molecule, methods for promoting reduction of the antigen concentration in plasma by administering antigen-binding molecules, and methods for improving the plasma retention of an antigen-binding molecule, as well as antigen-binding molecules that allow enhanced antigen uptake into cells, antigen-binding molecules having an increased number of times of antigen binding, antigen-binding molecules that can promote reduction of the antigen concentration in plasma when administered, antigen-binding molecules with improved plasma retention, pharmaceutical compositions comprising the above antigen-binding molecules, and methods for producing them. The present inventors revealed that the above objective can be achieved by using antigen-binding molecules that show calcium-dependent antigen-antibody reaction. | 08-21-2014 |
20140271617 | ION CONCENTRATION-DEPENDENT BINDING MOLECULE LIBRARY - Disclosed is a library consisting essentially of a plurality of antigen-binding molecules differing in sequence from each other, wherein an antigen-binding domain in each of the antigen-binding molecules comprises at least one amino acid residue that changes the antigen-binding activity of the antigen-binding molecule depending on ion concentration conditions. Also disclosed are a composition comprising a plurality of polynucleotide molecules each encoding the antigen-binding molecules, a composition comprising a plurality of vectors each comprising the polynucleotide molecules, a method for selecting the antigen-binding molecules, a method for isolating the polynucleotide molecules, a method for producing the antigen-binding molecules, and a pharmaceutical composition comprising any of the antigen-binding molecules. | 09-18-2014 |
Takayoshi Shimizu, Shizuoka JP
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20110027695 | RESIN COMPOSITION FOR FUEL CELL SEPARATOR, PROCESS FOR PRODUCING SAME, AND FUEL CELL SEPARATOR - A fuel cell separator is produced by forming a fuel cell separator resin composition including, as essential components, (A) an epoxy resin; (B) a curing agent; (C) a curing accelerator; and (D) a carbon material, in which the content of the (D) is 50 to 85% by mass based on the total amount of the composition, in which the (D) includes high crystalline artificial graphite having an average particle size of 100 μm or more and less than 150 μm in an amount of 5 to 100% by mass based on the total amount of the (D), and in which the content of the (C) is 0.1 to 20 parts by weight per 100 parts by weight of the (B). The resin composition is excellent in electric conductivity and fluidity and contains little impurities, and can provide a fuel cell separator which is excellent in electric conductivity and dimensional accuracy, and has no fear of causing deterioration in performance of a solid electrolyte. | 02-03-2011 |
Tomohiko Shimizu, Shizuoka JP
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20140106600 | LEVER CONNECTOR - A lever connector includes a female connector, a male connector and a layer. The female connector includes a frame having a flange portion protruding toward a straight direction perpendicular to a direction in which the female connector and the male connector are to be fitted with each other. The flange portion includes a locking portion with flexibility. The lever includes a locked portion locked with the locking portion in a normal fitted state. The locking portion does not abut on a hole edge of an attachment hole formed on a panel in a state where the locked portion is locked with the locking portion, and abuts on the hole edge of the attachment hole in a state where the locked portion is not locked with the locking portion. | 04-17-2014 |
20140113469 | LEVER-TYPE CONNECTOR - A lever-type connector ( | 04-24-2014 |
20140113476 | LEVER-FITTING-TYPE CONNECTOR - A boss drawing-in groove of a lever includes: a lever inversion groove portion configured to cause the lever drawing-in boss to rotate the lever in an opposite direction opposite to a fitting rotation direction, in response to an insertion of a male connector into a hood with the lever being positioned at an initial rotation position; a drawing-in groove portion configured to guide the lever drawing-in boss by a rotating operation of the lever in the fitting rotation direction and cause the male connector to be fitted into a female connector; and a lever inertial rotation portion configured to rotate in the fitting rotation direction due to an inertial force of the lever after rotation of the lever in the opposite direction and cause the lever drawing-in boss to move to the drawing-in groove portion. | 04-24-2014 |
20140148031 | LEVER-TYPE CONNECTOR - A lever-type connector includes a first connector, a second connector, and a lever that rotates to fit the first connector and the second connector together, the first connector and the second connector being mounted into a mounting hole of a panel when the first and second connectors are in a fitted state. The lever includes a flexible locking portion. The first connector includes a locked portion with which the locking portion is engaged in a manner such that the lever rotates to bend the locking portion when the first and second connectors are properly fitted together. The locking portion includes a regulating portion positioned to face an edge portion of the mounting hole of the panel when the first connector and the second connector properly fitted together are mounted in the mounting hole so as to prevent the engagement between the locking portion and the locked portion from being released. | 05-29-2014 |
20140235081 | LEVER-TYPE CONNECTOR - This lever-type connector ( | 08-21-2014 |
20150126080 | CONNECTION STRUCTURE - In a connection structure, electric wire includes an inclined sheath section between an exposed core wire section and a whole circumferential sheath section. In the inclined sheath section, an end surface of the insulating sheath on one end side in a longitudinal direction inclines in a direction intersecting the longitudinal direction and thereby a portion of the core wire is exposed. Each of crimping pieces of a terminal has a core wire crimping section that crimps the exposed core wire section, a whole circumferential sheath crimping section that crimps the whole circumferential sheath section, and an inclined sheath crimping section that crimps the inclined sheath section. The terminal is crimped to the electric wire so that the end surface of the inclined sheath section faces a base plate section of the terminal. | 05-07-2015 |
Tomohito Shimizu, Shizuoka JP
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20120082796 | CURTAIN COATING METHOD AND CURTAIN COATING APPARATUS - A curtain coating method including: ejecting at least one layer of a coating liquid from a slit, and making the ejected coating liquid fall freely from a curtain nozzle lip by using a curtain edge guide which guides the coating liquid in the form of a curtain liquid film, so as to apply the coating liquid onto a continuously running web, wherein the coating liquid is applied by moving the curtain edge guide toward the depth direction when the curtain liquid film is seen from the front. | 04-05-2012 |
Tomoya Shimizu, Shizuoka JP
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20090221758 | PERFLUOROELASTOMER COMPOSITION AND MOLDED ARTICLE HEREOF - The present invention provides a perfluoroelastomer composition comprising: a perfluoroelastomer having a nitrogen-containing curing site; and a catalyst mixture comprising: a tertiary amine; and an organic dicarboxylic acid represented by general formula (1) or (2) in an amount of 0.4 to 2 mol per mol of the tertiary amine: | 09-03-2009 |
Toshiroh Shimizu, Shizuoka JP
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20080256480 | DATA GATHERING AND PROCESSING SYSTEM - A data gathering and processing system capable of efficiently gathering data and easily putting gathered data to secondary use in various applications. The data gathering and processing system includes an XML file generation unit that generates a structured document with data describing the layout of a data entry screen that includes input data, an item extraction unit that extracts, as a search item, at least a tag name from the structured document with data, an XML database that stores, in association with at least a portion of the structured document with data, the search item extracted by the item extraction unit from the structured document with data, a search criteria setting unit that receives a search item and a search criteria from a searcher, and a search execution unit that searches the XML database based on the search criteria, and presents input data obtained as a search result or a data entry screen that includes the input data. | 10-16-2008 |
Tsukasa Shimizu, Shizuoka JP
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20150122569 | SADDLE-TYPE ELECTRIC VEHICLE - An electric two-wheel vehicle includes a battery case that accommodates two batteries. The battery case is open in an upward direction. A head pipe supports a steering shaft and is connected to a front portion of the battery case. The battery case includes a beam portion that is disposed between the two batteries and extends rearward from a front wall portion of the battery case. Accordingly, it is possible to easily attach and detach the batteries with respect to a vehicle body for charging, protect the batteries, and secure the rigidity of a vehicle body frame. | 05-07-2015 |
Tsutomu Shimizu, Shizuoka JP
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20080213788 | GENE CODING FOR SCYTALONE DEHYDRATASE EXHIBITING RESISTANCE TO AGRICULTURAL FUNGICIDAL AGENT - The present invention provides a gene that can be used extensively in studies relating to resistant rice blast fungi. | 09-04-2008 |
20090300803 | GENE CODING FOR ACETOLACTATE SYNTHASE - The present invention provides a gene coding for the following protein (a) or (b) showing a high level of resistance to PC herbicides or sulfonylurea herbicides: | 12-03-2009 |
Yuzo Shimizu, Shizuoka JP
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20100178524 | POLYESTER RESIN COMPOSITION, PRODUCTION METHOD THEREOF AND LAMINATE POLYESTER FILM - The present invention is a composition containing a polyester resin containing at least an alicyclic dicarboxylic acid component and an alicyclic diol component, and it is a polyester resin composition which satisfies that a glass transition temperature is 65° C. or more and 90° C. or less, a refractive index at sodium D line is 1.500 or more and 1.570 or less, a titanium element content is 5 ppm or more and 500 ppm or less, a phosphorus element content is 50 ppm or more and 500 ppm or less and a gel fraction is 50% or less. By the present invention, it is possible to obtain a polyester resin composition having a low refractive index and photoelastic coefficient, and in which a thermally degraded foreign substance is reduced. | 07-15-2010 |