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Shih, US

Alan M. Shih, Birmingham, AL US

Patent application numberDescriptionPublished
20100295921Virtual Interactive Presence Systems and Methods - Provided herein are methods and systems for virtual interactive presence.11-25-2010

Albert Shih, Ann Arbor, MI US

Patent application numberDescriptionPublished
20100065458SPECIMEN MANAGEMENT SYSTEM - A tray system for storing and transporting specimens, such as slides and paraffin blocks, includes a first tray having a top face with a first portion including a plurality of first compartments and a second portion adjacent the first portion including a plurality of second compartments, a width of the first compartments greater than a width of the second compartments. A top rim extends upwardly from the top face along a periphery of the first portion, and a bottom rim extends downwardly from an opposed bottom face about a perimeter corresponding to the periphery of the first portion on the top face. A second tray has a top face including a plurality of generally rectangular compartments each including flanges extending only partially across the compartment. A top rim extends upwardly around a perimeter of the top face, and a bottom rim extends downwardly around a perimeter of a bottom face. Both the first and second tray top rims are configured to receive both the first and second tray bottom rims to allow for interchangeable stacking of the first and second trays.03-18-2010

Albert J. Shih, Ann Arbor, MI US

Patent application numberDescriptionPublished
20110004204Surgical Instrument and Method for Use Thereof - A surgical instrument for treating a tissue includes a handpiece and a tissue engaging portion arranged to be received by the handpiece. The tissue engaging portion includes first and second opposed jaw members having an open position and a closed position for engaging the tissue therebetween, where the first and second jaw members are arranged to receive surgical energy from a surgical generator. The tissue engaging portion further includes at least one cooling member spaced from at least one of the first and second jaw members, where the cooling member has an open position and a closed position for engaging the tissue. Positioning the jaw members in their closed position and applying surgical energy to the tissue allows for treatment of the tissue, and positioning the cooling member in its closed position provides at least one of a pressure gradient or a thermal gradient between the jaw members and the cooling member.01-06-2011
20140039371ACTIVE EXOSKELETAL SPINAL ORTHOSIS AND METHOD OF ORTHOTIC TREATMENT - An active exoskeletal spinal orthosis that can reduce the spinal compression and muscle effort involved in resisting gravitational bending moments. The spinal orthosis includes upper and lower members that fit around the body in the area of the spine. Actuators extend between the upper and lower members. By applying a corrective moment, a distraction force, or both to a user via the actuators, the spinal orthosis allows for supported multi-planar maneuverability within a set range of motion. A controller activates the actuators based on sensor feedback that is indicative of pressure or some other sensed physical parameter related to the bending moment.02-06-2014
20140128678AMBIDEXTROUS ERGONOMIC FACE MASK - A face mask that may be used for bag-mask ventilation, during the induction of general anesthesia for example, and allows for two-handed or ambidextrous use. The face mask includes a dome connected to a deformable rim, which forms an enclosed air space when the rim is pressed against a patient's face. The dome has a connection port and a contoured outer surface adjacent the connection port. The contoured outer surface includes contour features such as a pair of crossed composite recesses which may each receive a different one of a user's thumbs. The connection port is aligned with the patient's mouth when the mask is in use and an adapter may be included that attaches to the connection port and provides a ventilation port as well as an intubation port that is aligned with the mouth.05-08-2014

Patent applications by Albert J. Shih, Ann Arbor, MI US

Amy Shih, Ann Arbor, MI US

Patent application numberDescriptionPublished
20090143476Antimicrobial Nanoemulsion Compositions and Methods - The present invention relates to compositions and methods for decreasing the infectivity, morbidity, and rate of mortality associated with a variety of pathogenic organisms and viruses. The present invention also relates to methods and compositions for decontaminating areas colonized or otherwise infected by pathogenic organisms and viruses. Moreover, the present invention relates to methods and compositions for decreasing the infectivity of pathogenic organisms in foodstuffs.06-04-2009
20090143477Antimicrobial Nanoemulsion Compositions and Methods - The present invention relates to compositions and methods for decreasing the infectivity, morbidity, and rate of mortality associated with a variety of pathogenic organisms and viruses. The present invention also relates to methods and compositions for decontaminating areas colonized or otherwise infected by pathogenic organisms and viruses. Moreover, the present invention relates to methods and compositions for decreasing the infectivity of pathogenic organisms in foodstuffs.06-04-2009
20100003330ANTIMICROBIAL NANOEMULSION COMPOSITIONS AND METHODS - The present invention relates to compositions and methods for decreasing the infectivity, morbidity, and rate of mortality associated with a variety of pathogenic organisms and viruses. The present invention also relates to methods and compositions for decontaminating areas colonized or otherwise infected by pathogenic organisms and viruses. Moreover, the present invention relates to methods and compositions for decreasing the infectivity of pathogenic organisms in foodstuffs.01-07-2010
20110070306Antimicrobial nanoemulsion compositions and methods - The present invention relates to compositions and methods for decreasing the infectivity, morbidity, and rate of mortality associated with a variety of pathogenic organisms and viruses. The present invention also relates to methods and compositions for decontaminating areas colonized or otherwise infected by pathogenic organisms and viruses. Moreover, the present invention relates to methods and compositions for decreasing the infectivity of pathogenic organisms in foodstuffs.03-24-2011
20110091556Antimicrobial compositions and methods of use - The present invention relates to compositions and methods for decreasing the infectivity, morbidity, and rate of mortality associated with a variety of pathogenic organisms and viruses. The present invention also relates to methods and compositions for decontaminating areas colonized or otherwise infected by pathogenic organisms and viruses. Moreover, the present invention relates to methods and compositions for decreasing the infectivity of pathogenic organisms in foodstuffs. In particular, decreased pathogenic organism infectivity, morbidity, and mortality is accomplished by contacting the pathogenic organism with an oil-in-water nanoemulsion comprising an oil, an organic solvent, and a surfactant dispersed in an aqueous phase.04-21-2011

Patent applications by Amy Shih, Ann Arbor, MI US

Chuan Shih, Carmel, IN US

Patent application numberDescriptionPublished
20080269244Kinase Inhibitors - The present invention provides kinase inhibitors of Formula (I). Wherein R10-30-2008
20080275056Pyrazole-Isoquinoline Urea Derivatives as P38 Kinase Inhibitors - The present invention provides kinase inhibitors of Formula (I) wherein R1, R2, and X are as described herein, or a pharmaceutically acceptable salt thereof.11-06-2008
20080306068Kinase Inhibitors - The present invention provides kinase inhibitors of Formula I:12-11-2008
20080306082[4-(Benzo[B]Thiophen-2-Yl) Pyrimidin-2-Yl]-Amine Derivatives As Ikk-Beta Inhibitors For The Treatment Of Cancer And Inflammatory Diseases - The present invention provides compounds of Formula I: useful in the treatment of cancer and inflammatory diseases.12-11-2008
20090036445KINASE INHIBITORS - The present invention provides kinase inhibitors of Formula I.02-05-2009
20090318443KINASE INHIBITORS - The present invention provides kinase inhibitors of Formula I.12-24-2009
20100022529AMIDOPHENOXYINDAZOLES USEFUL AS INHIBITORS OF C-MET - The present invention provides amidophenoxyindazole compounds useful in the treatment of cancer.01-28-2010

Patent applications by Chuan Shih, Carmel, IN US

Chuang-Tsair Shih US

Patent application numberDescriptionPublished
20130253968FACILITY CONTROL SYSTEM (FCS, C1) TO MANAGE ASSETS PLANNING, DESIGN, CONSTRUCTION, FABRICATION, OPERATING, MAINTENCE AND PRODUCTS - A facility control system includes lab, field and construction equipment with a wireless transceiver to transmit machine generated actual initial measurement (AIM) data including GPS information from a field activity to a wide area network; a mobile computer with a wireless transceiver to transmit human generated data from an office, a remote lab, or a field test or inspection to the network; and a server coupled to the network, the server including a database to receive machine and human generated AIM data, wherein the server applies statistics and engineering methods to predict specification compliance and performance, wherein the AIM data is used with pre-formatted engineered designed data sheets that reflect the exact location of the event and required standards including incorporating best construction practices for installation of one or more construction items and materials quality to promote standardization, uniformity that insures contract compliance and minimizes non-conforming items in real time.09-26-2013
20140058963FACILITY CONTROL SYSTEM (FCS-C2) (INTRODUCTION OF TRAVELER FORM) TO MANAGE ASSETS PLANNING, DESIGN, CONSTRUCTION, FABRICATION, OPERATING, MAINTENCE AND PRODUCTS FABRICATION - A facility control system includes lab, field and construction equipment with a wireless transceiver to transmit machine generated actual initial measurement (AIM) data including GPS information from a field activity to a wide area network; a mobile computer with a wireless transceiver to transmit human generated data from an office, a remote lab, or a field test to the network; and a server coupled to the network, the server including a database to receive machine and human generated AIM data, wherein the server applies statistics and engineering methods to predict specification compliance and performance, wherein the AIM data is used with pre-formatted engineered designed data sheets, including checklist/traveler form, that reflect the exact location of the event and required standards including incorporating best construction practices for installation of construction items and materials quality to promote standardization, uniformity that insures contract compliance and minimizes non-conforming items in real time.02-27-2014

Chuming Shih, Acton, MA US

Patent application numberDescriptionPublished
20130037924ANTENNA SWITCH MODULES AND METHODS OF MAKING THE SAME - Antenna switch modules and methods of making the same are provided. In certain implementations, an antenna switch module includes a package substrate, an integrated filter, and a silicon on insulator (SOI) die attached to the package substrate. The SOI die includes a capacitor configured to operate in the integrated filter and a multi throw switch for selecting amongst the RF signal paths. In some implementations, a surface mount inductor is attached to the package substrate adjacent the SOI die and is configured to operate in the integrated filter with the capacitor. In certain implementations, the inductor is formed from a conductive layer of the package substrate disposed beneath a layer of the package substrate used to attach the SOI die.02-14-2013

Chuming Shih, Chandler, AZ US

Patent application numberDescriptionPublished
20140009213BODY-GATE COUPLING TO REDUCE DISTORTION IN RADIO-FREQUENCY SWITCH - Radio-frequency (RF) switch circuits are disclosed having one or more transistors coupled to provide improved harmonic management. The RF switch circuits including at least one field-effect transistor (FET) disposed between first and second nodes, each of the at least one FET having a respective body and gate. A coupling circuit can be configured to couple the respective body and gate of each of the at least one FET. The coupling circuit can include a capacitor electrically parallel with a diode.01-09-2014
20140009214CIRCUITS, DEVICES, METHODS AND APPLICATIONS RELATED TO SILICON-ON-INSULATOR BASED RADIO-FREQUENCY SWITCHES - Radio-frequency (RF) switch circuits are disclosed providing improved switching performance. An RF switch system includes a plurality of field-effect transistors (FETs) connected in series between first and second nodes, each FET having a gate and a body. A compensation network including a gate-coupling circuit couples the gates of each pair of neighboring FETs. The compensation network may further including a body-coupling circuit that couples the bodies of each pair of neighboring FETs.01-09-2014
20140300525METHODS FOR ANTENNA SWITCH MODULES - Methods for antenna switch modules are disclosed. In certain implementations, a method of making an antenna switch module is provided. The method includes providing a package substrate implemented to receive one or more electrical components, attaching a silicon on insulator (SOI) die to the package substrate, and providing an integrated filter. The SOI die includes a capacitor and a switch coupled to a plurality of radio frequency (RF) signal paths. The integrated filter filters an RF signal received on a first RF signal path of the plurality of RF signal paths, and includes the capacitor of the SOI die and an inductor.10-09-2014

Chung Shih, Sandy, UT US

Patent application numberDescriptionPublished
20090048346THERAPEUTIC FORMULATIONS - The present invention features pharmaceutical compositions that improve the bioavailability of hydrophobic pharmaceutical agents that induce apoptosis in mammalian cells. Also featured are injectable formulations for the parenteral delivery of such hydrophobic pharmaceutical agents into patients in need of such treatment, as well as methods of making and using both the compositions and formulations, including methods for the treatment of cell proliferation or hyperproliferative diseases and disorders.02-19-2009
20090069350PHARMACEUTICAL COMPOSITIONS AND USE THEREOF - The present invention relates to pharmaceutical compositions and dosage compositions of compounds, including injectable formulations for the parenteral delivery of such compounds into patients in need of such treatment. Also featured are methods of making and using the compositions, including methods for the treatment of neoplastic diseases.03-12-2009
20090075962GROWTH STIMULANT COMPOSITIONS - An improved weight and growth stimulant for domesticated animals such as cattle, pigs and sheep is comprised of an anabolic agent that is subcutaneously administered in the form of a dual release implant formulation. Increased gains are particularly improved when zeranol is administered in an immediate-release and controlled-release formulation which allows for a one-time dosage injection.03-19-2009
20090264537BIODEGRADABLE BLOCK COPOLYMERIC COMPOSITIONS FOR DRUG DELIVERY - An improved drug delivery composition and method of use is disclosed. The composition comprises one or more biodegradable block copolymer drug carriers; and a reconstitution enhancing and enabling agent comprising polyethylene glycol (PEG), a PEG derivative or a mixture of PEG and a PEG derivative. The composition can be administered as is or after being be dissolved or rapidly reconstituted in an aqueous vehicle to afford a homogeneous solution or uniform colloidal systems.10-22-2009
20100076067BIODEGRADABLE BLOCK COPOLYMERIC COMPOSITIONS FOR DRUG DELIVERY - An improved drug delivery composition and method of use is disclosed. The composition comprises one or more biodegradable block copolymer drug carriers; and a reconstitution enhancing and enabling agent comprising polyethylene glycol (PEG), a PEG derivative or a mixture of PEG and a PEG derivative. The composition can be administered as is or after being be dissolved or rapidly reconstituted in an aqueous vehicle to afford a homogeneous solution or uniform colloidal systems.03-25-2010
20140105857COMPOSITIONS AND METHODS FOR ENHANCING ACTIVE AGENT ABSORPTION - Compositions and methods for enhancing the absorption of active agents across the mucosa of animal subjects are provided. Methods of administration and appropriate dosage forms are also provided.04-17-2014
20140113975BIODEGRADABLE BLOCK COPOLYMERIC COMPOSITIONS FOR DRUG DELIVERY - An improved drug delivery composition and method of use is disclosed. The composition comprises one or more biodegradable block copolymer drug carriers; and a reconstitution enhancing and enabling agent comprising polyethylene glycol (PEG), a PEG derivative or a mixture of PEG and a PEG derivative. The composition can be administered as is or after being be dissolved or rapidly reconstituted in an aqueous vehicle to afford a homogeneous solution or uniform colloidal systems.04-24-2014

Patent applications by Chung Shih, Sandy, UT US

Daniel Tzu-Bi Shih, Lake Oswego, OR US

Patent application numberDescriptionPublished
20110052622REISHI-MEDIATED ENHANCEMENT OF HUMAN TISSUE PROGENITOR CELL ADHESION AND DIFFERENTIATION - The present disclosure provides medicinally active extracts and fractions, and methods for using the same to increase eukaryotic cell adhesion, to increase differentiation of eukaryotic cells to produce increased numbers of immature dendritic cells, to enhance or accelerate condrogenesis of MSCs, to maintain undifferentiated CD03-03-2011
20120094380HUMAN MULTIPOTENT EMBRYONIC STEM CELL-LIKE PROGENITOR CELLS - The invention provides a plurality of embryonic stem cell-like progenitor cells, which are isolated from a human tissue by a systemic screening of human mesenchymal stromal stem/progenitor cells and a cell sorting by a cell antigen selected from the group consisting of CD34, CD117, CD133, CD201, GloboH and combination thereof, and cultured in a medium supplemented with at least one or more steroids and one or more growth factors. The cells of the invention express CD34 and exhibit sphere-like clonogenicity in early passages and express multipotent embryonic stem cells (ESCs) like characteristics.04-19-2012

Da-Yuan Shih, Armonk, NY US

Patent application numberDescriptionPublished
20110156256ELECTROMIGRATION-RESISTANT UNDER-BUMP METALLIZATION OF NICKEL-IRON ALLOYS FOR SN-RICH SOLDER BUMPS OF PB-FREE FLIP-CHIP APPLICATIONS - A process comprises manufacturing an electromigration-resistant under-bump metallization (UBM) flip chip structure comprising a Cu layer by applying to the Cu layer a metallic reaction barrier layer comprising NiFe. The solder employed in the flip chip structure comprise substantially lead-free tin. A structure comprises a product produced by this process. In another embodiment a process comprises manufacturing an electromigration-resistant UBM Sn-rich Pb-free solder bump flip chip structure wherein the electromigration-resistant UBM structure comprises a four-layer structure, or a three-layer structure, wherein the four layer structure is formed by providing 1) an adhesion layer, 2) a Cu seed layer for plating, 3) a reaction barrier layer, and 4) a wettable layer for joining to the solder, and the three-layer structure is formed by providing 1) an adhesion layer, 2) a reaction barrier layer, and 3) a wettable layer. In a further embodiment, the reaction barrier layer comprises metals selected from Ni, Fe, Pd, Pt, Co, Cu and their alloys, and combinations thereof. A structure comprises a product produced by the immediately foregoing process.06-30-2011
20120252168Copper Post Solder Bumps on Substrate - A method comprises forming semiconductor flip chip interconnects where the flip chip comprises a wafer and a substrate having electrical connecting pads and electrically conductive posts operatively associated with the pads and extending away from the pads to terminate in distal ends. Solder bumping the distal ends by injection molding solder onto the distal ends produces a solder bumped substrate. Another embodiment comprises providing the substrate having the posts on the pads with a mask having a plurality of through hole reservoirs and aligning the reservoirs in the mask to be substantially concentric with the distal ends. This is followed by injecting liquid solder into the reservoirs to provide a volume of liquid solder on the distal ends, cooling the liquid solder in the reservoirs to solidify the solder, removing the mask to expose the solidified solder after the cooling and thereby provide a solder bumped substrate. This is followed by positioning the solder bumped substrate on a wafer in a manner that leaves a gap between the wafer and the substrate. The wafer has electrically conductive sites on the surface for soldering to the posts. Abutting the sites and the solder bumped posts followed by heating the solder to its liquidus temperature joins the wafer and substrate, after which, the gap is optionally filled with a material comprising an underfill.10-04-2012
20130062757No Flow Underfill or Wafer Level Underfill and Solder Columns - A preassembly semiconductor device comprises substrate soldering structures extending toward chip soldering structures for forming solder connections with the chip soldering structures, i.e., the chip and the substrate are in preassembly positions relative to one another. The height of the substrate soldering structures is greater than the height of the chip soldering structures. A pre-applied underfill is contiguous with the substrate and is sufficiently thick so as to extend substantially no further than the full height of the substrate soldering structures. In another embodiment the height of the chip soldering structures is greater than the height of the substrate soldering structures and the pre-applied underfill is contiguous with the semiconductor chip and sufficiently thick so as to extend substantially no further than the full height of the chip soldering structures. A process comprises manufacturing semiconductor assemblies from these devices by soldering the semiconductor chip and the substrate to one another.03-14-2013
20140057392Copper Post Solder Bumps on Substrates - A method comprises forming semiconductor flip chip interconnects having electrical connecting pads and electrically conductive posts terminating in distal ends operatively associated with the pads. We solder bump the distal ends by injection molding, mask the posts on the pads with a mask having a plurality of through hole reservoirs and align the reservoirs in the mask to be substantially concentric with the distal ends. Injecting liquid solder into the reservoirs and allowing it to cool provides solidified solder on the distal ends, which after mask removal produces a solder bumped substrate which we position on a wafer to leave a gap between the wafer and the substrate. The wafer has electrically conductive sites on the surface for soldering to the posts. Abutting the sites and the solder bumped posts followed by heating joins the wafer and substrate. The gap is optionally filled with a material comprising an underfill.02-27-2014
20140170816Copper Post Solder Bumps on Substrates - A method comprises forming semiconductor flip chip interconnects having electrical connecting pads and electrically conductive posts terminating in distal ends operatively associated with the pads. We solder bump the distal ends by injection molding, mask the posts on the pads with a mask having a plurality of through hole reservoirs and align the reservoirs in the mask to be substantially concentric with the distal ends. Injecting liquid solder into the reservoirs and allowing it to cool provides solidified solder on the distal ends, which after mask removal produces a solder bumped substrate which we position on a wafer to leave a gap between the wafer and the substrate. The wafer has electrically conductive sites on the surface for soldering to the posts. Abutting the sites and the solder bumped posts followed by heating joins the wafer and substrate. The gap is optionally filled with a material comprising an underfill.06-19-2014
20140370662Copper Post Solder Bumps on Substrates - A method comprises forming semiconductor flip chip interconnects having electrical connecting pads and electrically conductive posts terminating in distal ends operatively associated with the pads. We solder bump the distal ends by injection molding, mask the posts on the pads with a mask having a plurality of through hole reservoirs and align the reservoirs in the mask to be substantially concentric with the distal ends. Injecting liquid solder into the reservoirs and allowing it to cool provides solidified solder on the distal ends, which after mask removal produces a solder bumped substrate which we position on a wafer to leave a gap between the wafer and the substrate. The wafer has electrically conductive sites on the surface for soldering to the posts. Abutting the sites and the solder bumped posts followed by heating joins the wafer and substrate. The gap is optionally filled with a material comprising an underfill.12-18-2014
20150031173COPPER POST SOLDER BUMPS ON SUBSTRATES - A method comprises forming semiconductor flip chip interconnects having electrical connecting pads and electrically conductive posts terminating in distal ends operatively associated with the pads. We solder bump the distal ends by injection molding, mask the posts on the pads with a mask having a plurality of through hole reservoirs and align the reservoirs in the mask to be substantially concentric with the distal ends. Injecting liquid solder into the reservoirs and allowing it to cool provides solidified solder on the distal ends, which after mask removal produces a solder bumped substrate which we position on a wafer to leave a gap between the wafer and the substrate. The wafer has electrically conductive sites on the surface for soldering to the posts. Abutting the sites and the solder bumped posts followed by heating joins the wafer and substrate. The gap is optionally filled with a material comprising an underfill.01-29-2015

Patent applications by Da-Yuan Shih, Armonk, NY US

Eugene I. Shih, Cambridge, MA US

Patent application numberDescriptionPublished
20090082689METHOD AND APPARATUS FOR REDUCING THE NUMBER OF CHANNELS IN AN EEG-BASED EPILEPTIC SEIZURE DETECTOR - An ambulatory patient-specific epileptic seizure detector based on scalp EEG signals is presented. A method for selecting a patient-specific subset of electrodes from a plurality of m EEG channels needed to detect an epileptic seizure in the patient is also presented. Seizure EEG data is collected from the plurality of m EEG channels. An effective subset n of the channels of the plurality of m EEG channels is selected using recursive feature processing and a detector is constructed in response to the subset n of channels. The performance of the detector in detecting seizures is then estimated.03-26-2009

Eugene Inghaw Shih, Brookline, MA US

Patent application numberDescriptionPublished
20140072190Linear-Based Eulerian Motion Modulation - In one embodiment, a method of amplifying temporal variation in at least two images comprises examining pixel values of the at least two images. The temporal variation of the pixel values between the at least two images can be below a particular threshold. The method can further include applying signal processing to the pixel values.03-13-2014
20140267919MODIFYING A DIGITAL VIDEO SIGNAL TO MASK BIOLOGICAL INFORMATION - Techniques are disclosed to process certain information contained in a digital video signal. In particular, a time-varying signal present in the digit video signal may be supplanted with a replacement time-varying signal, negated, or obfuscated with a noise signal. Negation of the time-varying signal may include extracting said time-varying signal from the digital video signal, inverting the time-varying signal, and adding the inverted time-varying signal to the original digital video signal. Obfuscation of the time-varying signal may be accomplished by introducing a suitable noise signal to the original digital video signal. Supplanting the time-varying signal with a replacement signal may include negating the time-varying signal and introducing a desired replacement signal to the digital video signal.09-18-2014

Eugen Inghaw Shih, Brookline, MA US

Patent application numberDescriptionPublished
20140072229Complex-Valued Phase-Based Eulerian Motion Modulation - In one embodiment, a method of amplifying temporal variation in at least two images includes converting two or more images to a transform representation. The method further includes, for each spatial position within the two or more images, examining a plurality of coefficient values. The method additionally includes calculating a first vector based on the plurality of coefficient values. The first vector can represent change from a first image to a second image of the at least two images describing deformation. The method also includes modifying the first vector to create a second vector. The method further includes calculating a second plurality of coefficients based on the second vector.03-13-2014

Fuming Shih, Cambridge, MA US

Patent application numberDescriptionPublished
20120265717LEARNING SITUATIONS VIA PATTERN MATCHING - Example methods, apparatuses, or articles of manufacture are disclosed herein that may be utilized, in whole or in part, to facilitate or support one or more operations or techniques for machine learning of situations via pattern matching or recognition.10-18-2012

Garret Shih, Brookline, MA US

Patent application numberDescriptionPublished
20130177058Method And Apparatus To Track Gain Variation In Orthogonal Frequency Division Multiplexing (OFDM)Systems - Gain variations during a packet can lead to significant performance degradation in communications systems that use high order quadrature amplitude modulation (QAM). A method and the associated apparatus track such variations in an OFDM system and completely eliminate any performance degradation. Gain estimation and compensation is employed with the use of pilot subcarriers in the payload of an OFDM data packet. Estimated pilot magnitude ratios are averaged, throughout the processing life of a packet, to yield accurate gain estimations. A gain compensation factor is used to adjust data carriers. An exclusion method is also employed to eliminate pilot carriers which contribute to noise.07-11-2013
20130279635Automatic Gain Control (AGC) For Multichannel/Wideband Communications System - Automatic Gain Control (AGC) system for multi-channel signals attenuates an incoming multi-channel signal by providing a gain. The system further adjusts each individual channel, of the multi-channel signal, by supplying a second gain if needed. The AGC system is designed to ensure a received signal power is at an optimal level for analog to digital conversion or any other form of signal processing. The system also enables elimination of mid-packet gain adjustments.10-24-2013

Garret Webster Shih, Brookline, MA US

Patent application numberDescriptionPublished
20140006908INTERPROCESSOR COMMUNICATIONS SYSTEMS AND METHODS01-02-2014
20140071869DYNAMIC POWER SCALING OF DIGITAL MODEMS - A system and method dynamically scale power consumed by the circuitry of an electronic device based on channel state and/or data rate. The electronic device then operates according to the power scaling. The scaling may be in accordance with an effective data rate, a number of multiple input multiple output (MIMO) layers, receiver type, a cell scenario, or a number of carriers. A number of MIMO layers can be predicted based on at least one of channel conditions or a channel quality index (CQI).03-13-2014

George Shih, New York, NY US

Patent application numberDescriptionPublished
20100088121MEDICAL INFORMATION NOTIFICATION SYSTEM USING SECURE WIRELESS AND/OR WIRED COMMUNICATION - A system for reporting medical information to healthcare provider users may require users to acknowledge receipt of information. Information may be sent using a secure instant messaging (SIM) protocol, and users may acknowledge receipt, e.g., by sending a message, or clicking on a uniform resource locator (URL) or button included in the information. Unacknowledged information may be re-sent at designated time intervals, and may have different levels of urgency indicated in the message. Acknowledgement may be tracked by the system, e.g., by recording the user and timestamp of acknowledgement. Feeds or syndications (e.g., RSS, RDF, Atom, etc.) may be used to provide medical information, allowing users to subscribe to feeds for one or more patients. Feeds may be continuously aggregated and updated with the most recent information for each of the patients. Users can easily distinguish new information from information already accessed, thereby allowing the healthcare provider to efficiently sort through the medical data.04-08-2010
20120106817SYSTEM AND METHOD FOR RADIATION DOSE REPORTING - Systems and method can be employed to automatically extract radiation dose information from medical images, particularly a plurality of heterogeneous CT images including those from legacy CT scanners. A report including the extracted radiation dose information can be generated, and alerts can be sent to reduce the possibility of overexposures.05-03-2012

Han-Jung Shih US

Patent application numberDescriptionPublished
20100177004Multi-band printed antenna - The present invention discloses a multi-band printed antenna, comprising: a grounding plane; and an antenna part, including a shorted arm electrically connected to the grounding plane, a folded arm connected to the shorted arm, and a feeding arm connected to the folded arm, feeding arm being for providing signals to the folded arm and shorted arm; wherein the folded arm includes at least one turning corner and provides at least two resonant frequencies according to the turning corner and the total length of the folded arm.07-15-2010

Heather H. Shih, Andover, MA US

Patent application numberDescriptionPublished
20100158924Expression of the cysteine protease legumain in vascular and inflammatory diseases - The present invention provides isolated and purified polynucleotides, polypeptides, and antibodies related to mammalian (e.g., mouse and human) legumain and the novel legumain splice variant, ZB-1. The invention further relates to the use of these isolated and purified polynucleotides, polypeptides, and antibodies, as well as other legumain and ZB-1 agonists and antagonists, in modulating legumain and/or ZB-1 activity, expression, and/or secretion in a cell or cell population, e.g., monocytes, macrophages, foam cells, vascular endothelial cells, kidney proximal tubule cells, arterial endothelial cells, sites of inflammatory cell invasion into a vessel intima, and neointimal lesional areas of an artery. The invention also provides legumain and ZB-1 antagonists, e.g., antagonistic small molecules, antibodies and antibody fragments to legumain and ZB-1, legumain and ZB-1 inhibitory polypeptides, and legumain and ZB-1 inhibitory polynucleotides. The present invention is also directed to novel methods for diagnosing, prognosing, monitoring, treating, ameliorating and/or preventing vascular disorders/diseases and inflammatory disorders/diseases.06-24-2010

Ie-Ming Shih, Baltimore, MD US

Patent application numberDescriptionPublished
20110171741DNA INTEGRITY ASSAY (DIA) FOR CANCER DIAGNOSTICS, USING CONFOCAL FLUORESCENCE SPECTROSCOPY - The present invention relates, e.g., to a method for determining the size distribution of DNA molecules in a sample comprising cell-free nucleic acid, comprising labeling the DNA with a fluorescent dye in a stoichiometric manner, subjecting the DNA to molecular spectroscopy (e.g., cylindrical illumination confocal spectroscopy), analyzing suitable fluorescent burst parameters of the labeled DNA, and conducting single molecule DNA integrity analysis of the labeled DNA molecules in the sample. In one embodiment of the invention, the method is used as a diagnostic method for detecting cancer.07-14-2011

Jason C.h. Shih, Cary, NC US

Patent application numberDescriptionPublished
20110286994METHODS AND COMPOSITIONS FOR IMPROVING GROWTH OF MEAT-TYPE POULTRY - The present invention provides methods of improving growth performance, improving the efficiency of feed utilization, increasing feed digestibility, and decreasing mortality of immature and developing animals receiving animal feed. Methods of producing a crude keratinase enzyme extract and animal feed supplements for achieving the same are also provided.11-24-2011
20140044700METHODS AND COMPOSITIONS FOR IMPROVING GROWTH OF MEAT-TYPE POULTRY - The present invention provides methods of improving growth performance, improving the efficiency of feed utilization, increasing feed digestibility, and decreasing mortality of immature and developing animals receiving animal feed. Methods of producing a crude keratinise enzyme extract and animal feed supplements for achieving the same are also provided.02-13-2014
20150037458METHODS AND COMPOSITIONS FOR IMPROVING GROWTH OF MEAT-TYPE POULTRY - The present invention provides methods of improving growth performance, improving the efficiency of feed utilization, increasing feed digestibility, and decreasing mortality of immature and developing animals receiving animal feed. Methods of producing a crude keratinise enzyme extract and animal feed supplements for achieving the same are also provided.02-05-2015

Patent applications by Jason C.h. Shih, Cary, NC US

Jen-Chieh Shih US

Patent application numberDescriptionPublished
20110244378DEVICE AND METHOD FOR PROVIDING WAVELENGTH REDUCTION WITH A PHOTOMASK - Disclosed is a photomask having a wavelength-reducing material that may be used during photolithographic processing. In one example, the photomask includes a transparent substrate, an absorption layer having at least one opening, and a layer of wavelength-reducing material (WRM) placed into the opening. The thickness of the WRM may range from approximately a thickness of the absorption layer to approximately ten times the wavelength of light used during the photolithographic processing. In another example, the photomask includes at least one antireflection coating (ARC) layer.10-06-2011

Jennifer Shih, Corvallis, OR US

Patent application numberDescriptionPublished
20080280398System And Method For Direct Bonding Of Substrates - A method of forming a MEMS (Micro-Electro-Mechanical System), includes forming an ambient port through a MEMS cap which defines a cavity containing a plurality of MEMS actuators therein; and bonding a lid arrangement to the MEMS cap to hermetically seal the ambient port.11-13-2008

Patent applications by Jennifer Shih, Corvallis, OR US

Jerry Shih, Cumming, GA US

Patent application numberDescriptionPublished
20140040405Method and Apparatus for Messaging Service Internetworking - A method and system for converting data message formats in a message server is provided. The message server receives a first data message including origin format information from a first user. The message server then sends the first data message including origin format information to a second user. The message server receives a second data message from a second user, the second data message including the origin format. The second data message is converted to the origin format if the first user is unable to receive the second data message. The message server then sends the converted second data message to the first user.02-06-2014

Jessie W. Shih, Lake Forest, IL US

Patent application numberDescriptionPublished
20080280377HUMAN B-TYPE NATRIURETIC PEPTIDE ASSAY HAVING REDUCED CROSS-REACTIVITY WITH OTHER PEPTIDE FORMS - The present disclosure provides among other things assays, methods and kits for assessing the presence or amount of human B-type natriuretic peptide in a test sample wherein the assay exhibits reduced cross-reactivity with other forms of the peptide.11-13-2008
20080286818BLOOD SAMPLE HANDLING METHODS FOR IMPROVED ASSAYS FOR MYELOPEROXIDASE - The invention provides a method for determining concentration of myeloperoxidase (MPO) in a human blood sample comprising: (a) providing a human peripheral blood sample stored under MPO preservation conditions; and (b) determining concentration of MPO in a plasma sample derived from the human peripheral blood sample. In a preferred embodiment, the MPO preservation conditions used in the invention comprise storage of the human peripheral blood sample in a plasma collection tube containing a leukocyte MPO secretion inhibitor. In this embodiment, the leukocyte MPO secretion inhibitor is preferably ethylene diamine tetraacetic acid (EDTA). The assays used in the inventive methods can comprise any clinically useful assay for determining MPO plasma concentration, including sandwich and competitive immunoassays, clinical chemistry assays and enzymatic assays.11-20-2008
20090123473HUMAN BNP IMMUNOSPECIFIC ANTIBODIES - The present invention relates to antibodies that immunospecifically bind to human brain natriuretic peptide or a human brain natriuretic peptide fragment with a high binding affinity, methods for producing and selecting said antibodies, immunoassays for human brain natriuretic peptide or a human brain natriuretic peptide fragment that employ said antibodies and therapeutic compositions containing said antibodies.05-14-2009
20090148866Antibodies and Improved Test Sample Handling Methods for Use in Assays for Myeloperoxidase - The present disclosure relates to isolated antibodies that can be used in an assay to determine the concentration levels of myeloperoxidase (MPO) in a test sample. Additionally, the present disclosure also relates to the use of improved test sample handling methods in assays in order to preserve the original MPO levels in the test sample.06-11-2009
20110053179Biomarkers For Prediction Of Major Adverse Cardiac Events And Uses Thereof - The present invention relates to combinations of biomarkers and levels thereof that may be used, for example, in the determination of risk associated with the occurrence of a major adverse cardiac event (MACE) in a patient.03-03-2011
20110201130HUMAN B-TYPE NATRIURETIC PEPTIDE ASSAY HAVING REDUCED CROSS-REACTIVITY WITH OTHER PEPTIDE FORMS - The present disclosure provides among other things assays, methods and kits for assessing the presence or amount of human B-type natriuretic peptide in a test sample wherein the assay exhibits reduced cross-reactivity with other forms of the peptide.08-18-2011
20130288269Biomarkers For Prediction Of Major Adverse Cardiac Events And Uses Thereof - The present invention relates to combinations of biomarkers and levels thereof that may be used, for example, in the determination of risk associated with the occurrence of a major adverse cardiac event (MACE) in a patient.10-31-2013

Patent applications by Jessie W. Shih, Lake Forest, IL US

Joanna L. Shih, Downers Grove, IL US

Patent application numberDescriptionPublished
20110092743PRODUCTION AND COMPOSITION OF GLYCEROL BASED POLYOLS - The invention provides a method of efficiently producing branched, cyclic glycerol-based polyols with a co-product as anti-biodegrading agent from inexpensive readily available glycerol monomer. The method involves polymerizing glycerol or glycerol with at least another monomer to multiple other monomers in the presence of particular amount of a strong base as the catalyst under a particular distillation environment. The polyol produced by the inventive method is beneficial of reducing scales in Bayer liquid for aluminum production process and improving brightness of coated paper substrates without greening effect.04-21-2011
20120238776GLYCEROL BASED POLYMER SURFACE ACTIVE CHEMISTRY AND PRODUCTION - The invention provides a method of efficiently producing branched, cyclic glycerol-based polymer surface active products having ester and alkyl functional groups with a co-product as anti-biodegrading agent from inexpensive readily available glycerol monomer. The method involves polymerizing glycerol or glycerol with at least another monomer to multiple other monomers in the presence of particular amount of a strong base as the catalyst under a particular distillation environment. The polyol then undergoes esterification, alkylation and crosslinking in presence of particular amount of a catalyst under a particular low activity atmospheric environment. The glycerol-based polymer surface active products produced by the inventive method are beneficial for reducing lignin, extractives and rejects levels in pulping process of papermaking industry.09-20-2012

Keith S. Shih, Loveland, OH US

Patent application numberDescriptionPublished
20080271866Paper substrate containing a functional layer and methods of making and using the same - The invention relates to the papermaking art and, in particular, to the manufacture of paper or paperboard substrates, paper-containing articles such as multilayered paper or paperboard or corrugated-based packaging, having a functional layer, as well as methods of making and using the same.11-06-2008

Min-Yi Shih, Carson City, NV US

Patent application numberDescriptionPublished
20080239306SYSTEM AND METHOD FOR OPTICAL POWER MANAGEMENT - A system and method for managing optical power for controlling thermal alteration of a sample undergoing spectroscopic analysis is provided. The system includes a moveable laser beam generator for irradiating the sample and a beam shaping device for moving and shaping the laser beam to prevent thermal overload or build up in the sample. The moveable laser beam generator includes at least one beam shaping device selected from the group consisting of at least one optical lens, at least one optical diffractor, at least one optical path difference modulator, at least one moveable mirror, at least one Micro-Electro-Mechanical Systems (MEMS) integrated circuit (IC), and/or a liquid droplet. The system also includes an at least two degree of freedom (2 DOF) moveable substrate platform and a controller for controlling the laser beam generator and the substrate platform, and for analyzing light reflected from the sample.10-02-2008

Min-Yi Shih, Niskayuna, NY US

Patent application numberDescriptionPublished
20090201497OPTOFLUIDIC DEVICES AND METHODS OF USING THE SAME - An optofluidic device is provided. The device includes a cladding region having a first refractive index, and a channel defined by the cladding region such that the cladding region forms an inner surface or an interface of the channel. The channel is configured to house one or more of a liquid, a solid, a gas, a colloidal, or a suspension sample, wherein the sample has a second refractive index, where the channel is configured to guide radiation, and where the first refractive index is lower than the second refractive index.08-13-2009

Patent applications by Min-Yi Shih, Niskayuna, NY US

Neng-Yang Shih, Cambridge, MA US

Patent application numberDescriptionPublished
20110189192NOVEL COMPOUNDS THAT ARE ERK INHIBITORS - Disclosed are the ERK inhibitors of formula 1.0: and the pharmaceutically acceptable salts, and solvates thereof. Q is a tetrahydropyridinyl ring. All other substitutents are as defined herein. Also disclosed are methods of treating cancer using the compounds of formula 1.0.08-04-2011

Peter Shih, Ellicott City, MD US

Patent application numberDescriptionPublished
20110051883RACK SYSTEMS AND ASSEMBLIES FOR FUEL STORAGE - A rack assembly for nuclear fuel assemblies generally includes a frame assembly and a container assembly including a plurality of individual fuel containers designed to contain individual fuel assemblies, wherein the individual fuel containers are received within and supported by the frame assembly. The rack assembly further includes a shielding assembly including at least one of an inner shielding assembly comprising a substantially continuous shield between the individual fuel containers and an outer shielding assembly comprising a substantially continuous shield around at least a portion of the outer surfaces of the rack assembly. A rack storage system generally includes a plurality of rack assemblies.03-03-2011

Po-Jen Shih, Columbia, MD US

Patent application numberDescriptionPublished
20080227107COMPOSITIONS AND METHODS FOR LABELING OF NUCLEIC ACID MOLECULES - The present invention is generally related to compositions, kits and methods for labeling nucleic acid molecules using reverse transcriptases, preferably multi-subunit reverse transcriptases such as ASLV reverse transcriptases. Specifically, the invention relates to methods, kits and compositions for fluorescently labeling nucleic acid molecules during nucleic acid synthesis. The labeled nucleic acid molecules produced in accordance with the invention are particularly suited as labeled probes for nucleic acid detection and diagnostics.09-18-2008
20090176242COMPOSITIONS AND METHODS FOR LABELING OF NUCLEIC ACID MOLECULES - The present invention is generally related to compositions, kits and methods for labeling nucleic acid molecules using reverse transcriptases, preferably multi-subunit reverse transcriptases such as ASLV reverse transcriptases. Specifically, the invention relates to methods, kits and compositions for fluorescently labeling nucleic acid molecules during nucleic acid synthesis. The labeled nucleic acid molecules produced in accordance with the invention are particularly suited as labeled probes for nucleic acid detection and diagnostics.07-09-2009
20100168408COMPOSITIONS AND METHODS FOR LABELING OF NUCLEIC ACID MOLECULES - The present invention is generally related to compositions, kits and methods for labeling nucleic acid molecules using reverse transcriptases, preferably multi-subunit reverse transcriptases such as ASLV reverse transcriptases. Specifically, the invention relates to methods, kits and compositions for to fluorescently labeling nucleic acid molecules during nucleic acid synthesis. The labeled nucleic acid molecules produced in accordance with the invention are particularly suited as labeled probes for nucleic acid detection and diagnostics.07-01-2010

Patent applications by Po-Jen Shih, Columbia, MD US

Po-Jen Shih, Webster, NY US

Patent application numberDescriptionPublished
20110159176METHOD OF MAKING FUSER MEMBER - A method of making a fuser member having an annealed outer surface comprising: providing an outer layer comprising compatible first and second fluorothermoplastics over an outer substrate surface, wherein the first fluorothermoplastic is a crosslinkable polymer and the second fluorothermoplastic is a linear polymer; curing the outer layer to crosslink the first fluorothermoplastic whereby the resulting crosslinked first fluorothermoplastic and the linear polymer second fluorothermoplastic form a semi-interpenetrating polymer network (SIPN); and annealing an outer surface of the outer layer by contacting the fuser member with applied pressure against a heated surface, without first sintering the second fluorothermoplastic linear polymer through application of heat alone.06-30-2011
20110159276FUSER MEMBER WITH FLUOROPOLYMER OUTER LAYER - A fuser member comprising: a substrate comprising an outer substrate surface; and an outer layer comprising compatible first and second fluorothermoplastics disposed over the outer substrate surface, wherein the first fluorothermoplastic is a crosslinked polymer and the second fluorothermoplastic is a linear polymer and wherein the compatible first and second fluorothermoplastics form a semi-interpenetrating polymer network (SIPN). The SIPN provides a relatively compliant layer in comparison to use of the crosslinked polymer alone, and avoids the need for sintering of a layer formed from the linear polymer alone. The SIPN may be formed from an aqueous coated composition of polyperfluoroalkoxy-tetrafluoroethylene (PFA) and THV Fluoroplastics (FLC) polymers along with a soluble organic primary amine for crosslinking the THV Fluoroplastics (FLC).06-30-2011
20120077000PROCESS FOR PRODUCING AN IMAGE FROM POROUS MARKING PARTICLES - A process of producing an image including transferring porous polymeric marking particles to a receiver, and fixing the marking particles to the receiver by applying heat and pressure by contacting the marking particles with a heated fuser member including a topcoat layer having a storage modulus of at least 10 MPa at 175° C. In particular embodiments, the invention is specifically directed towards fusing porous toner materials, and enables reducing the image relief, toner spread, and differential gloss of resulting fused toner images. Higher gloss and reduced differential gloss is obtained at similar or reduced toner spread, measured by toner particle area gain, allowing the use of reduced fusing conditions compared to solid toners.03-29-2012

Raymond Shih, Elgin, IL US

Patent application numberDescriptionPublished
20130041175PROCESS FOR OXIDIZING ALKYL AROMATIC COMPOUNDS - A process for oxidizing an alkyl-aromatic compound is described. The process includes contacting the alkyl-aromatic compound, a solvent comprising an ionic liquid, a bromine source, a catalyst, and an oxidizing agent in a first reaction zone to produce a first product comprising a first mother liquor and at least one of an aromatic alcohol, an aromatic aldehyde, an aromatic ketone, and an aromatic carboxylic acid.02-14-2013
20140100403LOW PRESSURE TRANSALKYLATION PROCESS - A process for transalkylation is described. The process operates at a lower pressure than a typical transalkylation processes, and provides higher benzene purity with comparable or lower ring loss compared to the typical transalkylation process. The xylene selectivity is comparable to or higher than the standard process, and the ethyl benzene selectivity is comparable to or lower than the standard process.04-10-2014
20140171679OXIDATION AND CRYSTALLIZATION PROCESS FOR AROMATIC CARBOXYLIC ACID PRODUCTION - A process for oxidizing and crystallizing alkyl aromatics is described. The solvent and operating conditions are controlled to maintain the aromatic carboxylic acid in solution in the reaction zone, and the aromatic carboxylic acid is crystallized in a downstream crystallizer, resulting in reduced impurity levels in the product.06-19-2014

Raymond C. Shih, Elgin, IL US

Patent application numberDescriptionPublished
20130172606PROCESS FOR PRODUCING TEREPHTHALIC ACID - Methods and apparatus for producing terephthalic acid using a p-xylene stream enriched with p-toluic acid are described. The apparatus includes first and second reactor zones. The reactor zones can be in the same reactor or in different reactors.07-04-2013
20130172610PROCESS FOR OXIDIZING ALKYL-AROMATIC COMPOUNDS - A process for oxidizing an alkyl-aromatic compound is described. The process includes oxidizing the alkyl-aromatic compound to produce a first oxidation product; contacting at least a portion of the first oxidation product, a solvent comprising an ionic liquid, a bromine source, a catalyst, and an oxidizing agent to produce a second product comprising a mother liquor and at least one of an aromatic alcohol, an aromatic aldehyde, an aromatic ketone, and an aromatic carboxylic acid; and adding at least a portion of the mother liquor in the contacting step.07-04-2013

Sheau-Ling Shih, Poughkeepsie, NY US

Patent application numberDescriptionPublished
20090077537 METHOD OF AUTOMATICALLY GENERATING TEST CASES TO TEST COMMAND LINE INTERFACES - A computer program product stored on machine readable media is provided and includes machine executable instructions for testing a command of a computer code, the instructions including instructions for: receiving input from a command description file and an options file; and assembling a plurality of modified commands for testing of the command as a script.03-19-2009

Sheng-Hong Shih, Troy, MI US

Patent application numberDescriptionPublished
20140057501ELECTRICAL-MECHANICAL FASTENING DEVICE FOR MOTOR VEHICLES - An electro-mechanical fastener includes a fastener body having a connection portion materially integrally formed with at least one mounting member. The at least one mounting member has a thickness that is no more than three-times greater than a thickness of a substrate to which the electro-mechanical fastener is joined. The at least one mounting member is configured and disposed to be joined to the substrate through a welded connection.02-27-2014

Stuart S. Shih, Gainesville, VA US

Patent application numberDescriptionPublished
20100155300Process for producing gasoline of increased octane and hydrogen-containing co-produced stream - The present invention is directed to a process for producing an increased yield of gasoline of increased octane rating by the integration of a membrane separation processing step into the gasoline production process. The integrated process also increases hydrogen production from the reformer.06-24-2010
20100155332Process for improving the cetane rating of distillate and diesel boiling range fractions - The present invention is directed to a process for producing a diesel fuel of enhanced cetane value from low cetane distillate and diesel boiling range fractions from poor crudes such as naphthenic crudes.06-24-2010
20110132803TWO STAGE HYDROPROCESSING WITH DIVIDED WALL COLUMN FRACTIONATOR - A divided wall column allows for fractionation of multiple streams while maintaining separate product qualities. Effluents from multiple stages of a reaction system can be processed in a single divided wall column. The divided wall column can produce multiple cuts from each separated area, as well as at least one output from a common area.06-09-2011
20110240521HYDROPROCESSING OF GAS OIL BOILING RANGE FEEDS - A system and method for producing fuels and lubricant basestocks from gas oil boiling range feeds is provided. Desulfurization and conversion stages are used to form fuel and lubricant products. The product from a desulfurization stage can be fractionated, and a portion of the fractionated bottoms can be used as an input feed for a conversion or hydrocracking stage. The configuration can advantageously allow for reduced amounts of catalyst in the conversion stage.10-06-2011
20110282118METHOD FOR MAKING DIESEL WITH LOW POLYAROMATIC CONTENT - Distillate feeds are hydroprocessed to produce a product having a low content of polyaromatic hydrocarbons (PAHs). The hydroprocessing includes dewaxing and aromatic saturation of the feed. The temperature of the aromatic saturation process can be controlled to make a distillate product having a desired aromatic content, such as less the 0.02 wt % of polyaromatic hydrocarbons having three or more aromatic rings.11-17-2011
20120000817Production of Low Color Middle Distillate Fuels - In a process for producing a low color diesel and/or kerosene fuel, a middle distillate feed can be supplied to a reactor having at least one first catalyst bed containing a first desulfurization and/or isomerization catalyst and at least one second catalyst bed containing a decolorization catalyst downstream from the first catalyst bed(s). The feed can be reacted with the hydrogen in the presence of the first catalyst at a temperature from about 290° C. to about 430° C. to produce a first liquid effluent, which can be cooled by about 10° C. to about 40° C. with a quench medium and cascaded to the at least one second catalyst bed. The cooled first liquid effluent can then be reacted with hydrogen in the presence of the decolorization catalyst at a temperature from about 280° C. to about 415° C. to produce a second effluent having an ASTM color less than 2.5.01-05-2012
20120080357HYDROCRACKING PROCESS SELECTIVE FOR IMPROVED DISTILLATE AND IMPROVED LUBE YIELD AND PROPERTIES - This invention relates to a process involving hydrocracking of a feedstream in which a converted fraction can exhibit relatively high distillate product yields and maintained or improved distillate fuel properties, while an unconverted fraction can exhibit improved properties particularly useful in the lubricant area.04-05-2012
20120152803INCREASING FUEL SMOKE POINT - The present invention relates to processes for increasing smoke point of a fuel. The process can be carried out using an upgrading catalyst that contains at least one noble metal supported on an inorganic, porous crystalline phase material. The catalyst is particularly effective in increasing smoke point, while minimizing reduction in total aromatics content, particularly naphthalene content.06-21-2012
20120248008FUELS HYDROCRACKING WITH DEWAXING OF FUEL PRODUCTS - This invention relates to a process involving hydrocracking and dewaxing of a feedstream in which a converted fraction can correspond to a majority of the product from the reaction system, while an unconverted fraction can exhibit improved properties. In this hydrocracking process, it can be advantageous for the yield of unconverted fraction for gasoline fuel application to be controlled to maintain desirable cold flow properties for the unconverted fraction. Catalysts and conditions can be chosen to assist in attaining, or to optimize, desirable product yields and/or properties.10-04-2012
20130112594PRODUCTION OF LOW CLOUD POINT DISTILLATES - Systems and methods are provided for producing at least one low sulfur distillate fuel product with improved low temperature properties. A potential distillate fuel feed is initially hydrotreated to reduce sulfur and nitrogen levels in the feed to desired amounts. The hydrotreated effluent is then fractionated to form several fractions, including a light diesel/distillate fraction and a heavy diesel fraction. The heavy diesel fraction is then dewaxed to improve the cold flow properties of the heavy diesel fraction. The dewaxed heavy diesel fraction can be combined with the light diesel fraction, or the dewaxed heavy diesel fraction can be fractionated as well. Optionally, the heavy diesel fraction is dewaxed under conditions effective for producing a dewaxed fraction with a cloud point that is less than or equal to the cloud point of the light diesel/distillate fraction.05-09-2013
20130341243HYDROCRACKING PROCESS SELECTIVE FOR IMPROVED DISTILLATE AND IMPROVED LUBE YIELD AND PROPERTIES - This invention relates to a process involving hydrocracking of a feedstream in which a converted fraction can exhibit relatively high distillate product yields and maintained or improved distillate fuel properties, while an unconverted fraction can exhibit improved properties particularly useful in the lubricant area. In this hydrocracking process, it can be advantageous for the yield of converted/unconverted product for gasoline fuel application to be reduced or minimized, relative to converted distillate fuel and unconverted lubricant. Catalysts and conditions can be chosen to assist in attaining, or to optimize, desirable product yields and/or properties.12-26-2013

Patent applications by Stuart S. Shih, Gainesville, VA US

Tom I-Ping Shih, Ames, IA US

Patent application numberDescriptionPublished
20080245068METHOD AND APPARATUS FOR ENERGY HARVESTING THROUGH PHASE-CHANGE INDUCED PRESSURE RISE UNDER COOLING CONDITIONS - A method and apparatus for generating power which includes a phase-change media (PCM) that expands upon cooling contained within an expandable capsule if the phase change involves solidification (if phase change is solid-solid, then capsules are not needed), a carrier liquid that does not freeze in the operating temperature range, a heat exchanger, and an engine. Alternatively, the method and apparatus can include a PCM contained within a layer next to the walls of a constant volume container, a working liquid within the container that does not freeze in the operating temperature range, a heat exchanger, and an engine. In both cases, the engine denotes a device that converts the energy in the high-pressure liquid into electrical or mechanical power.10-09-2008

Wayne Ken Shih, Kingsport, TN US

Patent application numberDescriptionPublished
20110081510MELT STRENGTH ENHANCED COPOLYESTER WITH IMPROVED STABILITY AND PROFILE IN BLOWN FILM - The invention relates to blown films and methods of making blown films using a melt-strength enhanced polyester composition. The composition has a zero-shear viscosity and a degree of shear thinning that are comparable to PVC's melt rheology. The polyester composition has a branching agent and/or a fluoropolymer processing additive and an inherent viscosity of at least 0.60 dl/g. The diacid component of the polyester composition comprises 97 to 100 mole percent of residues of terephthalic acid, naphthalenedicarboxylic acid, isophthalic acid or mixtures thereof. The glycol component of the polyester composition comprises 97 to 100 mole percent of residues of ethylene glycol, 1,4-cyclohexanedimethanol, diethylene glycol, neopentyl glycol or mixtures thereof.04-07-2011
20110091705RADIO-FREQUENCY SEALABLE POLYMER AND ARTICLES THEREOF - The present invention relates to a reactor-grade copolyester composition having radio-frequency sealing capability. The present invention further relates to films and thermoformable packaging prepared from the reactor-grade copolyester composition.04-21-2011
20140162042COPOLYESTERS PLASTICIZED WITH POLYMERIC PLASTICIZER FOR SHRINK FILM APPLICATIONS - Disclosed is a shrink film containing a copolyester having a minimum crystallization half-time of at least 8.6 minutes and a polyester plasticizer having a weight-average molecular weight of 900 to 12,000 g/mol. The polyester plasticizer includes (i) a polyol component comprising residues of a polyol having 2 to 8 carbon atoms, and (ii) a diacid component comprising residues of a dicarboxylic acid having 4 to 12 carbon atoms.06-12-2014
20140238585RADIO-FREQUENCY SEALABLE POLYMER AND ARTICLES THEREOF - The present invention relates to a reactor-grade copolyester composition having radio-frequency sealing capability. The present invention further relates to films and thermoformable packaging prepared from the reactor-grade copolyester composition and the methods for making such films and articles therefrom.08-28-2014

Wei-Chuan Shih, Cambridge, MA US

Patent application numberDescriptionPublished
20090039255METHOD AND APPARATUS FOR OIL SPILL DETECTION - The invention relates to a method for detecting the presence of hydrocarbons near an unmanned offshore oil platform. The method steps include monitoring reflected atmospheric and thermal radiation, detecting the presence of hydrocarbons, and generating an alert based on the presence of hydrocarbons.02-12-2009
20120095683METHOD AND APPARATUS FOR OIL SPILL DETECTION - The invention relates to a method for detecting the presence of hydrocarbons near an unmanned offshore oil platform. The method steps include monitoring reflected atmospheric and thermal radiation, detecting the presence of hydrocarbons, and generating an alert based on the presence of hydrocarbons.04-19-2012

Patent applications by Wei-Chuan Shih, Cambridge, MA US

William Shih, Cambridge, MA US

Patent application numberDescriptionPublished
20100216978WIREFRAME NANOSTRUCTURES - The present invention generally relates to nanotechnology and, in particular, to wireframe nanostructures which may be formed from nucleic acids. In various aspects, the invention relates to molecular structures having a plurality of vertices and pathways connecting the vertices, which may be formed from nucleic acids, including bundles or tubes of nucleic acids. Such molecular structures may form shapes such as icosahedrons, octahedrons, tetrahedrons, or other polyhedra, which may define an interior space. The interior space may be used, for example, to contain a molecule for further study, or to contain a molecule for drug delivery purposes. In some cases, the molecular structure may be stabilized using relatively short nucleic acid strands that interact with two or more nucleic acid portions within the structure, thereby substantially immobilizing the portions relative to each other. Other aspects of the invention relate to techniques for forming such molecular structures, techniques for using such molecular structures, techniques of promoting such molecular structures, kits involving such molecular structures, and the like.08-26-2010

William M. Shih, Cambridge, MA US

Patent application numberDescriptionPublished
20110089944NUCLEIC ACID NANOTUBE LIQUID CRYSTALS AND USE FOR NMR STRUCTURE DETERMINATION OF MEMBRANE PROTEINS - Compositions and methods for preparing nucleic acid nanotubes using DNA origami techniques are described, which provide for nanotubes of predictable and uniform length. The nucleic acid nanotubes thus formed are suitable as liquid crystal preparations enabling liquid-crystal NMR spectroscopy of proteins solubilized in detergent.04-21-2011
20110260105NUCLEIC ACID NANOTUBE LIQUID CRYSTALS AND USE FOR NMR STRUCTURE DETERMINATION OF MEMBRANE PROTEINS - Compositions and methods for preparing nucleic acid nanotubes using DNA origami techniques are described, which provide for nanotubes of predictable and uniform length. The nucleic acid nanotubes thus formed are suitable as liquid crystal preparations enabling liquid-crystal NMR spectroscopy of proteins solubilized in detergent.10-27-2011
20130261019NUCLEIC ACID NANOSTRUCTURE BARCODE PROBES - Provided herein are, inter alia, barcode probes comprised of transiently or stably fhiorescently labeled nucleic acid nanostructures that are fully addressable and able to be read using standard fluorescent microscope and methods of use thereof including methods of use as detectable labels for probes.10-03-2013
20150024972SELECTIVE NUCLEIC ACID AMPLIFICATION FROM NUCLEIC ACID POOLS - Provided herein are nucleic acids and methods for selectively amplifying in parallel tens of thousands of high quality oligonucleotides without common sequences. The resultant oligonucleotides can be used for a variety of purposes and applications including but not limited to DNA nano structure synthesis.01-22-2015
20150064233LIPID-COATED NUCLEIC ACID NANOSTRUCTURES OF DEFINED SHAPE - The invention provides nanoparticles containing a nucleic acid nanostructure, of defined shape and size, linked to a hydrophobic moiety and coated by lipids, compositions comprising the nanoparticles, and methods of producing and methods of using the nanoparticles.03-05-2015

Patent applications by William M. Shih, Cambridge, MA US

Winston Shih, New York, NY US

Patent application numberDescriptionPublished
20090212081SLOSH CONTROLLED PERSONAL HYDRATION SYSTEM - The present invention relates to a personal hydration system. In one exemplary embodiment, the personal hydration system may comprise a hydration reservoir for containing a supply of hydrating fluid, the hydration reservoir may comprise a plurality of compartments. The hydration reservoir may have a low profile and may comprise at least one baffle.08-27-2009
20100195057PROJECTION SYSTEMS FOR ACTIVITY BASED USERS - A projection system for displaying information which may include an electronic device and a projector connected to the electronic device. The electronic device and projector can be positioned on an article of clothing and/or an outdoor recreational product to project information therefrom. The article of clothing and/or outdoor recreational device may include a screen to enhance the projected information. The projector may be in connection with a power source.08-05-2010

Yichang Shih, Cambridge, MA US

Patent application numberDescriptionPublished
20140132761Laser Speckle Photography for Surface Tampering Detection - In one embodiment, a method comprises projecting, from a projector, a diffused on an object. The method further includes capturing, with a first camera in a particular location, a reference image of the object while the diffused is projected on the object. The method further includes capturing, with a second camera positioned in the particular location, a test image of the object while the diffused is projected on the object. The method further includes comparing speckles in the reference image to the test image. The projector, first camera and second camera are removably provided to and positioned in a site of the object.05-15-2014

Yichang Shih, Boston, MA US

Patent application numberDescriptionPublished
20130293761IMAGE ENHANCEMENT VIA CALIBRATED LENS SIMULATION - The description relates to enhancing images. One device includes a lens configured to focus images on an image sensor. The device also includes point spread function (PSF) lens data relating to manufacturing specifications of the lens and a PSF measurement of the lens associated with a test image of a planar calibration pattern at a single depth of field.11-07-2013

Yi-Chun Shih, Portland, OR US

Patent application numberDescriptionPublished
20140084881LOW DROPOUT REGULATOR WITH HYSTERETIC CONTROL - Described is an apparatus comprising: an output stage having an input supply node to receive an input power supply and an output node to provide an output supply to a load; an amplifier to control current strength of the output stage according to the output supply and a reference voltage; and a hysteresis unit to monitor the output supply and operable to control the current strength of the output stage according to a voltage level of the output supply. Described is another apparatus which comprises: a plurality of charge pumps to adjust current strength of the output stage; and a logic unit to monitor the output supply and operable to control the plurality of charge pumps according to a voltage level of the output supply and one or more reference voltages.03-27-2014
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