Patent application number | Description | Published |
20110051891 | COMPUTED TOMOGRAPHY EXAMINATION AND PARTICLE THERAPY TREATMENT - An operation room may comprise both an object scanning apparatus for examining an object using x-ray radiation and an irradiation component for treating an object using particle radiation. A support article upon which the object may reside during (both) the examination and treatment may be configured to rotate about an axis substantially perpendicular to a plane through which x-ray radiation travels, may be configured to tilt with respect to the axis, and/or may be configured to yaw with respect to the axis. In this way, the relative orientation of the support article and the object remain substantially constant during the examination and treatment to facilitate treating a desired area of the object. | 03-03-2011 |
20110176663 | FOCAL SPOT POSITION DETERMINER - One or more systems and/or techniques are disclosed herein for determining the orientation of a focal spot of a radiation source based upon shadows that are imposed on channels of a detector array from an anti-scatter grid. The anti-scatter grid is comprised of one or more anti-scatter plates that are focused on a point other than an intended focal spot of the radiation source. Such anti-scatters plates cast shadows on the detector array (even when the focal spot is located at the intended focal spot). By measuring changes in the signals generated by channels of the detector array that detect the shadows, it may be determined how the orientation of the focal spot has changed throughout an examination or between a calibration scan and an examination scan, for example. | 07-21-2011 |
20120056092 | X-RAY DETECTOR WITH IMPROVED QUANTUM EFFICIENCY - Among other things, one or more systems and/or techniques for integrating electrical charge yielded from an indirect conversion detector array of a pulsating radiation system are provided. The integration begins during a resting period between a first and second pulse and ends before the second pulse is emitted. Electrical charge that is measured during a resting period is integrated, while electrical charge measured during a pulse is not integrated. In this way, parasitic contributions caused by the direct interaction of radiation photons with a photodiode are reduced and a quantum efficiency of the indirect conversion detector array is increased, for example. Moreover, the period of integration can be adjusted such that a voltage gain related to the indirect conversion detector array can be varied to a predetermined level. | 03-08-2012 |
20120195410 | CLEANING APPARATUS AND/OR CLEANING TECHNIQUES FOR USE WITH A RADIOGRAPHIC EXAMINATION DEVICE - One or more techniques and/or systems are described herein for cleaning a portion of a radiographic examination apparatus whereon debris may accumulate. Typically, the portion being cleaned is within a scanning field of the radiographic examination device (e.g., within a portion of the radiographic examination device through which radiation traverses). Activation of a cleaning mechanism, or a portion thereof, may be timed to miss radiation emitted during a scan, and thus not interfere with a scan. Also, the cleaning mechanism, or a portion thereof, may be located so as to not attenuate radiation. If radiation is attenuated by the cleaning mechanism corrective techniques can be implemented to account for such attenuation. | 08-02-2012 |
Patent application number | Description | Published |
20100328670 | SYSTEM AND METHOD FOR PERFORMING PHOTOTHERMAL MEASUREMENTS AND RELAXATION COMPENSATION - A device and methods for performing a photothermal measurement and relaxation compensation of a sample are disclosed. The device may include a probe beam source, a pump beam source, a sample, and a detector array. A method may include adjusting an intensity modulated pump beam power, adjusting a probe beam power to increase a response measurement location temperature and increase a modulated optical reflectance signal, directing the intensity modulated pump beam and the probe beam along a measurement path to a response measurement location on a sample for periodically exciting a region on the sample, detecting a reflected portion of the probe beam, and calculating an implantation dose. | 12-30-2010 |
20130003050 | SYSTEM AND METHOD FOR NONDESTRUCTIVELY MEASURING CONCENTRATION AND THICKNESS OF DOPED SEMICONDUCTOR LAYERS - The disclosure is directed to nondestructive systems and methods for simultaneously measuring active carrier concentration and thickness of one or more doped semiconductor layers. Reflectance signals may be defined as functions of active carrier concentration and thickness varying over different wavelengths and over different incidence angles of analyzing illumination reflected off the surface of an analyzed sample. Systems and methods are provided for collecting a plurality of reflectance signals having either different wavelengths or different incidence angle ranges to extract active carrier density and thickness of one or more doped semiconductor layers. | 01-03-2013 |
20130169966 | Optical Metrology Tool Equipped with Modulated Illumination Sources - The present invention may include a modulatable illumination source configured to illuminate a surface of a sample disposed on a sample stage, a detector configured to detect illumination emanating from a surface of the sample, illumination optics configured to direct illumination from the modulatable illumination source to the surface of the sample, collection optics configured to direct illumination from the surface of the sample to the detector, and a modulation control system communicatively coupled to the modulatable illumination source, wherein the modulation control system is configured to modulate a drive current of the modulatable illumination source at a selected modulation frequency suitable for generating illumination having a selected coherence feature length. In addition, the present invention includes the time-sequential interleaving of outputs of multiple light sources to generate periodic pulses trains for use in multi-wavelength time-sequential optical metrology. | 07-04-2013 |
20140240951 | Systems for Providing Illumination in Optical Metrology - The disclosure is directed to systems for providing illumination to a measurement head for optical metrology. In some embodiments of the disclosure, illumination beams from a plurality of illumination sources are combined to deliver illumination at one or more selected wavelengths to the measurement head. In some embodiments of the disclosure, intensity and/or spatial coherence of illumination delivered to the measurement head is controlled. In some embodiments of the disclosure, illumination at one or more selected wavelengths is delivered from a broadband illumination source configured for providing illumination at a continuous range of wavelengths. | 08-28-2014 |
Patent application number | Description | Published |
20080234138 | TP53 gene expression and uses thereof - The present invention is drawn to diagnosis, prognosis and treatment of multiple myeloma. In this regard, the present invention discloses importance of down-regulation of TP3 gene in multiple myeloma and its use as an independent progostic indicator of multiple myeloma. Additionally, the present invention also discloses novel-TP53 associated genes and demonstrates the clinical relevance of these alterations to disease progression. | 09-25-2008 |
20080267950 | Molecular determinants of myeloma bone disease and uses thereof - The present invention is drawn to understanding lytic bone diseases. In this regard, the present invention discloses mechanism by which Wnt signaling antagonist inhibits bone differentiation. Also disclosed herein are methods to control bone loss, treat bone disease and prevent tumor growth in bones of individual. | 10-30-2008 |
20080274911 | Gene expression profiling based identification of genomic signature of high-risk multiple myeloma and uses thereof - The present invention discloses a method of applying novel bioinformatics and computational methodologies to data generated by high-resolution genome-wide comparative genomic hybridization and gene expression profiling on CD138-sorted plasma cells from a cohort of 92 newly diagnosed multiple myeloma patients treated with high dose chemotherapy and stem cell rescue. The results revealed that gains the q arm and loss of the p arm of chromosome 1 were highly correlated with altered expression of resident genes in this chromosome, with these changes strongly correlated with 1) risk of death from disease progression, 2) a gene expression based proliferation index, and 3) a recently described gene expression-based high-risk index. Importantly, we also found a strong correlation between copy number gains of 8q24, and increased expression of Argonate 2 (AGO2) a gene coding for a master regulator of microRNA expression and maturation, also being significantly correlated with outcome. Our novel findings significantly improve our understanding of the genomic structure of multiple myeloma and its relationship to clinical outcome. | 11-06-2008 |
20130338025 | USE OF GENE EXPRESSION PROFILING TO PREDICT SURVIVAL IN CANCER PATIENT - Gene expression profiling in multiple myeloma patients identifies genes that distinguish between patients with subsequent early death or long survival after treatment. Poor survival is linked to over-expression of genes such as ASPM, OPN3 and CKS1B which are located in chromosome 1q. Given the frequent amplification of 1q in many cancers, it is possible that these genes can be used as powerful prognostic markers and therapeutic targets for multiple myeloma and other cancer. | 12-19-2013 |
Patent application number | Description | Published |
20110047668 | SURGICAL PROTECTIVE SYSTEM HEAD GEAR ASSEMBLY INCLUDING HIGH VOLUME AIR DELIVERY SYSTEM - A surgical protective assembly having an air movement device and a head gear assembly carrying the air movement device. The head gear assembly includes an outer wall, an inner wall, a front end, a back end and a middle portion between the front end and the back end. The outer wall has an upper opening, the inner wall has an array of openings, and the inner and outer wall define a front opening at the front end. The head gear assembly has a passageway that fluidly connects together, the upper opening, the array and the front opening. | 03-03-2011 |
20110230828 | TUBING ASSEMBLY AND SIGNAL GENERATOR PLACEMENT CONTROL DEVICE AND METHOD FOR USE WITH CATHETER GUIDANCE SYSTEMS - A tubing assembly having a signal generator placement control device for use in conjunction with electronic catheter guidance systems. The control device facilitates control of the position the guidance systems' signal generator relative to the end of the tubing assembly. The tubing assembly includes a tubular insulator coupled to one end of the control device, and the tubing assembly includes a tubular connector attached to the other end of control device. Also, the tubing assembly includes a catheter attached to the tubular connector and an end member attached to the catheter. | 09-22-2011 |
20120216341 | SURGICAL PROTECTIVE SYSTEM HEAD GEAR ASSEMBLY INCLUDING HIGH VOLUME AIR DELIVERY SYSTEM - A surgical protective assembly having an air movement device and a head gear assembly carrying the air movement device. The head gear assembly includes an outer wall, an inner wall, a front end, a back end and a middle portion between the front end and the back end. The outer wall has an upper opening, the inner wall has an array of openings, and the inner and outer wall define a front opening at the front end. The head gear assembly has a passageway that fluidly connects together, the upper opening, the array and the front opening. | 08-30-2012 |
20120226148 | MEDICAL DEVICE POSITION GUIDANCE SYSTEM WITH WIRELESS CONNECTIVITY BETWEEN A NONINVASIVE AND AN INVASIVE DEVICE - A medical device position guidance system having a noninvasive medical device communicable with an invasive medical device. The system provides outputs useful to assess the position of an invasive medical device in an animal, such as a human. A magnetic field is used to gather information about the position of the invasive device. Radio waves are used to communicate this information between the noninvasive device and the invasive device. | 09-06-2012 |
20140196723 | BRIDLE DELIVERY SYSTEM, METHOD, AND APPARATUS FOR SECURING NASAL TUBES - Systems, methods, and apparatus for securing nasal tubes are disclosed. An exemplary system includes a bridle, a magnetic portion connected to the bridle, a delivery probe, a retrieval probe, and a clamp. The delivery probe includes an elongated member having proximal and distal ends, the distal end configured to deliver the magnetic portion, and a bridle lock configured to release the bridle upon actuation of an actuator. The retrieval probe includes an elongated member having proximal and distal ends, the distal end including a magnetic portion configured to magnetically couple with the other magnetic portion, and a magnetic coupling indicator configured to provide an indication in response to a magnetic coupling. The clamp includes a channel portion with an inside diameter larger than an outside diameter of a nasal tube. The clamp is configured to secure the nasal tube following placement of the bridle by the delivery and retrieval probes. | 07-17-2014 |
20160001043 | TUBING ASSEMBLY AND SIGNAL GENERATOR PLACEMENT CONTROL DEVICE AND METHOD FOR USE WITH CATHETER GUIDANCE SYSTEMS - A tubing assembly having a signal generator placement control device for use in conjunction with electronic catheter guidance systems. The control device facilitates control of the position the guidance systems' signal generator relative to the end of the tubing assembly. The tubing assembly includes a tubular insulator coupled to one end of the control device, and the tubing assembly includes a tubular connector attached to the other end of control device. Also, the tubing assembly includes a catheter attached to the tubular connector and an end member attached to the catheter. | 01-07-2016 |
Patent application number | Description | Published |
20120290642 | DYNAMIC NETWORK LINK ACCELERATION FOR NETWORK INCLUDING WIRELESS COMMUNICATION DEVICES - A method and apparatus for dynamic network link acceleration provides a managed communication link for accelerated and reliable network communication between a client and other network devices. In one or more embodiments, a client computing device which generates communication packets of a first type is enhanced with a front end mechanism which selectively encodes the data packets into packets of a second type. The data packets which are encoded into a second type are transmitted over a managed communication link which may provide error correction, security, quality of service, and other services including acceleration of communications. | 11-15-2012 |
20140289381 | OPTIMIZATION OF ENHANCED NETWORK LINKS - A method and apparatus for dynamic network link acceleration provides a managed communication link for accelerated and reliable network communication between a client and other network devices. In one or more embodiments, a client computing device which generates communication packets of a first type is enhanced with a front end mechanism which selectively encodes the data packets into packets of a second type. The data packets which are encoded into a second type are transmitted over a managed communication link which may provide error correction, security, quality of service, and other services including acceleration of communications. | 09-25-2014 |
20150381753 | OPTIMIZATION OF ENHANCED NETWORK LINKS - A method and apparatus for dynamic network link acceleration provides a managed communication link for accelerated and reliable network communication between a client and other network devices. In one or more embodiments, a client computing device which generates communication packets of a first type is enhanced with a front end mechanism which selectively encodes the data packets into packets of a second type. The data packets which are encoded into a second type are transmitted over a managed communication link which may provide error correction, security, quality of service, and other services including acceleration of communications. | 12-31-2015 |
Patent application number | Description | Published |
20130280671 | INTRA-ORAL LIGHT THERAPY APPARATUSES AND METHODS FOR THEIR USE - In some embodiments, an apparatus comprises a housing, an emitter, and an electronic circuit. The housing is configured to fit within a patient's mouth. The emitter is at least partially encased within the housing. The emitter is configured to emit an effective amount of light to the alveolar soft tissue when the housing is disposed within the mouth. The electronic circuit is operatively coupled to the emitter. The electronic circuit is configured to control the emitter when the housing is disposed within the mouth and the apparatus is in use during orthodontic treatment. The apparatus and its use for regulating tooth movement or maintaining or improving oral tissue health are disclosed herein. | 10-24-2013 |
20140072932 | INTRA-ORAL LIGHT THERAPY APPARATUSES AND METHODS FOR THEIR USE - In some embodiments, an apparatus comprises a housing, an emitter, and an electronic circuit. The housing is configured to fit within a patient's mouth. The emitter is at least partially encased within the housing. The emitter is configured to emit an effective amount of light to the alveolar soft tissue when the housing is disposed within the mouth. The electronic circuit is operatively coupled to the emitter. The electronic circuit is configured to control the emitter when the housing is disposed within the mouth and the apparatus is in use during orthodontic treatment. The apparatus and its use for regulating tooth movement or maintaining or improving oral tissue health are disclosed herein. | 03-13-2014 |
20150140502 | INTRA-ORAL LIGHT-THERAPY APPARATUSES AND METHODS FOR THEIR USE - In some embodiments, an apparatus comprises a housing, an emitter, and an electronic circuit. The housing is configured to fit within a patient's mouth. The emitter is at least partially encased within the housing. The emitter is configured to emit an effective amount of light to the alveolar soft tissue when the housing is disposed within the mouth. The electronic circuit is operatively coupled to the emitter. The electronic circuit is configured to control the emitter when the housing is disposed within the mouth and the apparatus is in use during orthodontic treatment. The apparatus and its use for regulating tooth movement or maintaining or improving oral tissue health are disclosed herein. | 05-21-2015 |