Sever, US
Christina Sever, Old Bridge, NJ US
Patent application number | Description | Published |
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20100040668 | Biomimetic Hydroxyapatite Composite Materials and Methods for the Preparation Thereof - The present invention is related to methods for preparing composite materials, which include nanoscale hydroxyapatite, and the composite materials and articles prepared therewith. | 02-18-2010 |
20130022527 | BIOMIMETIC HYDROXYAPATITE SYNTHESIS - A method for preparing nanoscale hydroxyapatite particles by combining an amount of a calcium ion source, which includes calcium acetate, and an amount of a phosphate ion source, wherein the amounts are sufficient to produce nanoscale hydroxyapatite particles and the amounts are combined under ambient conditions to produce the hydroxyapatite particles. Nanoscale hydroxyapatite particles are also presented. | 01-24-2013 |
20130022653 | BIOMIMETIC HYDROXYAPATITE SYNTHESIS - A method for preparing nanoscale hydroxyapatite particles by combining an amount of a calcium ion source, which includes calcium acetate, and an amount of a phosphate ion source, wherein the amounts are sufficient to produce nanoscale hydroxyapatite particles and the amounts are combined under ambient conditions to produce the hydroxyapatite particles. Nanoscale hydroxyapatite particles are also presented. | 01-24-2013 |
Clinton Sever, San Diego, CA US
Patent application number | Description | Published |
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20140336083 | SYSTEM FOR PORTABLE AND EASY-TO-USE DETECTION OF ANALYTES WITH MOBILE COMPUTING DEVICE - This system takes in raw cellular material collected using a provided swab, blood collection device, urine collection device, or other sample collection device and transforms that biological material into a digital result, identifying the presence, absence and/or quantity of nucleic acids, proteins, and/or other molecules of interest. | 11-13-2014 |
20150064693 | SYSTEMS AND METHODS FOR DETECTION AND QUANTIFICATION OF ANALYTES - Devices, systems, and methods for detecting molecules of interest within a collected sample are described herein. In certain embodiments, self-contained sample analysis systems are disclosed, which include a reusable reader component, a disposable cartridge component, and a disposable sample collection component. In some embodiments, the reader component communicates with a remote computing device for the digital transmission of test protocols and test results. In various disclosed embodiments, the systems, components, and methods are configured to identify the presence, absence, and/or quantity of particular nucleic acids, proteins, or other analytes of interest, for example, in order to test for the presence of one or more pathogens or contaminants in a sample. | 03-05-2015 |
20150068894 | SYSTEMS AND METHODS FOR DETECTION AND QUANTIFICATION OF ANALYTES - Devices, systems, and methods for detecting molecules of interest within a collected sample are described herein. In certain embodiments, self-contained sample analysis systems are disclosed, which include a reusable reader component, a disposable cartridge component, and a disposable sample collection component. In some embodiments, the reader component communicates with a remote computing device for the digital transmission of test protocols and test results. In various disclosed embodiments, the systems, components, and methods are configured to identify the presence, absence, and/or quantity of particular nucleic acids, proteins, or other analytes of interest, for example, in order to test for the presence of one or more pathogens or contaminants in a sample. | 03-12-2015 |
20150129049 | SYSTEMS AND METHODS FOR DETECTION AND QUANTIFICATION OF ANALYTES - Devices, systems, and methods for detecting molecules of interest within a collected sample are described herein. In certain embodiments, self-contained sample analysis systems are disclosed, which include a reusable reader component, a disposable cartridge component, and a disposable sample collection component. In some embodiments, the reader component communicates with a remote computing device for the digital transmission of test protocols and test results. In various disclosed embodiments, the systems, components, and methods are configured to identify the presence, absence, and/or quantity of particular nucleic acids, proteins, or other analytes of interest, for example, in order to test for the presence of one or more pathogens or contaminants in a sample. | 05-14-2015 |
20150133337 | SYSTEMS AND METHODS FOR DETECTION AND QUANTIFICATION OF ANALYTES - Devices, systems, and methods for detecting molecules of interest within a collected sample are described herein. In certain embodiments, self-contained sample analysis systems are disclosed, which include a reusable reader component, a disposable cartridge component, and a disposable sample collection component. In some embodiments, the reader component communicates with a remote computing device for the digital transmission of test protocols and test results. In various disclosed embodiments, the systems, components, and methods are configured to identify the presence, absence, and/or quantity of particular nucleic acids, proteins, or other analytes of interest, for example, in order to test for the presence of one or more pathogens or contaminants in a sample. | 05-14-2015 |
20150136599 | SYSTEMS AND METHODS FOR DETECTION AND QUANTIFICATION OF ANALYTES - Devices, systems, and methods for detecting molecules of interest within a collected sample are described herein. In certain embodiments, self-contained sample analysis systems are disclosed, which include a reusable reader component, a disposable cartridge component, and a disposable sample collection component. In some embodiments, the reader component communicates with a remote computing device for the digital transmission of test protocols and test results. In various disclosed embodiments, the systems, components, and methods are configured to identify the presence, absence, and/or quantity of particular nucleic acids, proteins, or other analytes of interest, for example, in order to test for the presence of one or more pathogens or contaminants in a sample. | 05-21-2015 |
20150140646 | SYSTEMS AND METHODS FOR DETECTION AND QUANTIFICATION OF ANALYTES - Devices, systems, and methods for detecting molecules of interest within a collected sample are described herein. In certain embodiments, self-contained sample analysis systems are disclosed, which include a reusable reader component, a disposable cartridge component, and a disposable sample collection component. In some embodiments, the reader component communicates with a remote computing device for the digital transmission of test protocols and test results. In various disclosed embodiments, the systems, components, and methods are configured to identify the presence, absence, and/or quantity of particular nucleic acids, proteins, or other analytes of interest, for example, in order to test for the presence of one or more pathogens or contaminants in a sample. | 05-21-2015 |
Edward J. Sever, Littleton, NC US
Patent application number | Description | Published |
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20110014427 | METHODS FOR FORMING FRITTED COVER SHEETS AND GLASS PACKAGES COMPRISING THE SAME - A method for forming a fritted cover sheet includes providing a substrate and depositing an initial frit bead on the substrate. Thereafter, at least one additional frit bead is deposited on the substrate such that a base of the at least one additional frit head contacts a base of an adjacent frit bead thereby forming a frit seal on the substrate. | 01-20-2011 |
Isaac Sever, Beaverton, OR US
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20160006289 | APPARATUS, SYSTEM AND METHOD OF WIRELESS POWER TRANSFER - Some demonstrative embodiments include apparatuses, systems and/or methods of wireless power transfer. For example, a Wireless Power Receiver (WPR) may include a rectifier to convert a wireless charging signal received from Wireless Power Transmitter (WPT into a Direct Current (DC) power signal; a voltage regulator to regulate a voltage of the DC power signal according to a voltage range; a bypass path to bypass the voltage regulator; and a bypass controller to select between directing the DC power signal to the voltage regulator or to the bypass path, based on a voltage level of the DC power signal and the voltage range. | 01-07-2016 |
John Sever, Pacific, MI US
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20110084432 | Fuel nozzle servicing tool - A tool for servicing a fuel dispensing nozzle, said tool comprising a substantially semicircular base plate with two uprights protruding from the top to receive a fuel pump nozzle therein; said base plate being formed to fit on the mouth of a bucket and substantially cover the mouth of said bucket, while leaving open a portion of the bucket; said base plate having on its bottom surface protruding guides to ensure a snug fit on the mouth of said bucket; so that a fuel dispensing nozzle may be easily secured for separation from a hose and residual fuel may be easily drained from said nozzle and said hose. | 04-14-2011 |
20110232803 | Modularized components assembled fluid dispensing nozzle - Modularized components assembled dispensing nozzle, including operating components in the category of a poppet valve assembly, an automatic shutoff device, a hand operating lever for providing a turn on or shutoff of the dispensing of fluid through the nozzle, and a connected spout that delivers fluid to the fill pipe and fuel tank for a vehicle or fluid accepting container. Each of the identified components having been redesigned for assembly in modularized form, such as a modular cartridge for the poppet valve, a modular cartridge for the automatic shutoff device, a modularized operating hand lever, and a spout and its gland and retaining nut that provide for high speed interconnection with the nozzle body, during assembly, or servicing. Each of these modularized components can be installed, during assembly of the manufactured nozzle, or can be replaced, out in the field, by a service person, as a modularized component or cartridge assembly. | 09-29-2011 |
20150007907 | Modularized components assembled fluid dispensing nozzle - Modularized components assembled dispensing nozzle, including operating components in the category of a poppet valve assembly, an automatic shutoff device, a hand operating lever for providing a turn on or shutoff of the dispensing of fluid through the nozzle, and a connected spout that delivers fluid to the fill pipe and fuel tank for a vehicle or fluid accepting container. Each of the identified components having been redesigned for assembly in modularized form, such as a modular cartridge for the poppet valve, a modular cartridge for the automatic shutoff device, a modularized operating hand lever, and a spout and its gland and retaining nut that provide for high speed interconnection with the nozzle body, during assembly, or servicing. Each of these modularized components can be installed, during assembly of the manufactured nozzle, or can be replaced, out in the field, by a service person, as a modularized component or cartridge assembly. | 01-08-2015 |
John C. Sever, Pacific, MO US
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20110114221 | Breakaway fuel hose cup - A cup for draining residual fuel from a breakaway hose coupling. The cup features a substantially cylindrical rigid stem extending upward from the floor of the cup reservoir, said stem featuring a cavity for receiving the pin of a breakaway hose valve. When the stem is pressed against the valve pin, the valve is opened, relieving pressure within the hose and releasing residual fuel within the hose. The residual fuel drains directly from the hose into the cup, facilitating safe and convenient disposal of the fuel, which may be poured using an integral pour spout in the cup rim. | 05-19-2011 |
John M. Sever, Lino Lakes, MN US
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20080202675 | Method for Handling Adhesive Laminate Sections - A method of handling an adhesive laminate, wherein the adhesive laminate is provided releasably adhered to a first web, comprising a plurality of cut or punched sections and wherein adjacent sections of the adhesive laminate remain joined to one another in the longitudinal direction of the web through one or more tie points. A first supporting structure and a second supporting structure adjacent to the first supporting structure are provided. The first web is led over the first supporting structure. A second web is provided and led over the second supporting structure, wherein the second web is oriented such that the release surface of the second web faces the first supporting structure. A leading portion of a first section of adhesive laminate from the first web is attached to the release surface of the second web and the second web is advanced such that the first section of the adhesive laminate is detached from a second section of adhesive laminate and the leading edge of the second section of adhesive laminate is adhered to the second web in a spaced apart configuration from the trailing edge of the first section of the adhesive laminate. A transdermal drug delivery device prepared by such a method. | 08-28-2008 |
20140066866 | METHOD FOR HANDLING ADHESIVE LAMINATE SECTIONS - A method of handling an adhesive laminate, wherein the adhesive laminate is provided releasably adhered to a first web, comprising a plurality of cut or punched sections and wherein adjacent sections of the adhesive laminate remain joined to one another in the longitudinal direction of the web through one or more tie points. A first supporting structure and a second supporting structure adjacent to the first supporting structure are provided. The first web is led over the first supporting structure. A second web is provided and led over the second supporting structure, wherein the second web is oriented such that the release surface of the second web faces the first supporting structure. A leading portion of a first section of adhesive laminate from the first web is attached to the release surface of the second web and the second web is advanced such that the first section of the adhesive laminate is detached from a second section of adhesive laminate and the leading edge of the second section of adhesive laminate is adhered to the second web in a spaced apart configuration from the trailing edge of the first section of the adhesive laminate. A transdermal drug delivery device prepared by such a method. | 03-06-2014 |
Julie Sever, Poqouson, VA US
Patent application number | Description | Published |
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20120304388 | THERAPEUTIC BLOCKS AND THEIR METHODS OF MANUFACTURE AND USE - An improved block system may comprise a plurality of individual members, each member geometrically equivalent in shape and equivalent in size in two dimensions, while being of varying thickness. The plurality of blocks may be of malleable and/or semi-compressible material, and covered with fabric or material suitable to easy cleaning and sterilization. The plurality of blocks are utilized in a manner either singly or in groups to accommodate and support a individual's head and neck while the individual is being treated for musculoskeletal disorders. The invention may be utilized with a standing or supine individual. The plurality of blocks are further of a shape making them easily handleable and stackeable by a therapist, physical trainer, or other professional. The invention may also be utilized in a like manner to support an individual's head and neck while performing other exercises or tasks requiring head support. | 12-06-2012 |
Michael D. Sever, Franklin, IN US
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20110297010 | Portable Grilling Apparatus - A portable grilling apparatus includes a power adapter having first and second receiving areas each configured to respectively receive a battery, the power adapter having circuitry for receiving electricity at the first and second receiving areas and producing a single electrical output. The apparatus includes a grill portion having a lower grill housing, a support element having a cooking surface for receiving food thereon, and an electrical heating element in the lower grill housing. The electrical heating element is positioned below the cooking surface and the electrical heating element is in electrical communication with the single electrical output circuitry. The apparatus includes a positioning portion operatively coupling the power adapter to the grill portion, the positioning portion having an attachment member for securement to an object. | 12-08-2011 |
Nancy E. Sever, Arlington Heights, IL US
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20120258909 | Solid Compositions - The present invention features solid compositions comprising amorphous Compound I. For instance, Compound I may be formulated in an amorphous solid dispersion which comprises a pharmaceutically acceptable hydrophilic polymer and preferably a pharmaceutically acceptable surfactant. | 10-11-2012 |
20140171481 | SOLID COMPOSITIONS - The present invention features solid compositions comprising amorphous Compound I. For instance, Compound I may be formulated in an amorphous solid dispersion which comprises a pharmaceutically acceptable hydrophilic polymer and preferably a pharmaceutically acceptable surfactant. | 06-19-2014 |
Nancy E. Sever, Northbrook, IL US
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20150258093 | SOLID ANTIVIRAL DOSAGE FORMS - The present disclosure relates to solid dosage forms comprising antiviral compounds and methods of using such dosage forms to treat antiviral infection. | 09-17-2015 |
Nicholas Joseph Sever, Portage, IN US
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20110258911 | BIOFUEL PRODUCTION METHOD AND SYSTEM - In an embodiment of the present invention, a renewable energy fuel is prepared by a process including the steps of: a) providing a renewable energy feedstock; b) providing an alcohol; c) providing a catalyst; d) mixing (a), (b), and (c) to form a blend; and e) homogenizing the blend at a pressure greater than 400 kilogram-force per square centimeter (Kg/cm2). | 10-27-2011 |
20140290128 | BIOFUEL PRODUCTION METHOD AND SYSTEM - In an embodiment of the present invention, a renewable energy fuel is prepared by a process including the steps of: a) providing a renewable energy feedstock; b) providing an alcohol; c) providing a catalyst; d) mixing (a), (b), and (c) to form a blend; and e) homogenizing the blend at a pressure greater than 400 kilogram-force per square centimeter (Kg/cm2). | 10-02-2014 |
Paul Sever, Cranberry Township, PA US
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20090245964 | Metal Coil Securing Apparatus and Method - A metal coil securing device is disclosed including a coil cover adapted to encompass a metal coil and a plurality of tie down straps affixed to the coil cover, with each tie down secured along a portion of its length to the coil cover such that each tie down has two free ends extending outward from the periphery of the coil cover. In one embodiment, the tie down straps are secured to a circular coil cover to intersect at an approximate center of the coil cover and extend radially outward therefrom. A method of securing a metal coil to a transport trailer is also disclosed generally including associating and securing the coil cover with the metal coil, loading the metal coil with the secured coil cover onto the transport trailer, and using the free ends of the tie down straps to secure the metal coil to the transport trailer. | 10-01-2009 |
Penny A. Sever, Palm Desert, CA US
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20090070951 | Hairbrush - A hairbrush includes a bristle holding member having a first end and a second end. A plurality of brush bristles are operably connected to such bristle holding member at predetermined locations thereon. A first handle member is operably connected to the first end of such bristle holding member. A second handle member is releasably securable to the second end of such bristle holding member. A securing mechanism has a first portion disposed on such bristle holding member and a second mating portion disposed on such second handle member for releasably securing such bristle holding member to such second handle member. | 03-19-2009 |
Robert Sever, Arlington Heights, IL US
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20090001042 | CONTAINER-CLOSURE SYSTEM FOR USE IN LYOPHILIZATION APPLICATIONS - A container closure system for use in lyophilization processes employing depressurization to initiate nucleation is provided. The present container closure system includes a container and a closure element disposed proximate to and adapted for sealing the opening of the container. The closure element includes a first sealing surface adapted for sealably contacting an interior surface of the container and a second sealing surface adapted for sealably contacting the top surface of the container when the container closure system is in a closed position. The closure element also includes a plurality of closure legs extending from the second sealing surface that define a plurality of side vents between each of the closure legs when the container closure system is in the open position. The length, thickness, number, and shape of the legs are chosen to produce an effective total side vent area that is at least 50% of the area of the container opening. Alternatively, the length, thickness, number, and shape of the legs are chosen to produce an effective total side vent area that is greater than the cumulative surface area of the outwardly facing surface of the closure legs. | 01-01-2009 |
20130236358 | SYSTEM AND METHOD FOR VIRUS INACTIVATION - Methods and systems for virus inactivation in the production or processing of biological or other sensitive substances are provided. The disclosed methods and systems for virus inactivation involve the key steps of dissolving carbon dioxide into biological or other sensitive substances; and treating the substance with the dissolved carbon dioxide at conditions which are less than critical pressure and temperature for a prescribed treatment time to inactivate at least 80% of the target virus or viruses contained within the biological or other sensitive substances. The disclosed carbon dioxide treatments for virus inactivation may optionally include concurrently or sequentially subjecting the substances with an acid treatment to lower the pH of the substance and inactivate viruses contained within the biological or other sensitive substance. Operating conditions for the disclosed carbon dioxide treatments preferably involve sparging carbon dioxide gas into the substance until the composition is saturated with carbon dioxide and is conducted at pressures below about 5 MPa; at temperatures of less than or equal to 30° C.; and for a treatment time of between about one minute and about 2000 minutes. | 09-12-2013 |
20140047851 | BULK FREEZING OF BIOPHARMACEUTICALS - A system and method for bulk freezing is provided. In one embodiment, the system and method for bulk freezing includes a bulk freezing container adapted to hold at least one and preferably a plurality of bags holding a biopharmaceutical liquid. The bulk freezing container includes at least a first and second shelf having corrugations wherein the second shelf is vertically arranged above the first shelf with the bags disposed between the shelves. The bags and the corrugations of the first and second shelves define a plurality of substantially parallel flow channels through which a cryogenic cold fluid or a warming fluid is passed to freeze and/or thaw the biopharmaceutical fluid. In another embodiment, the bulk freezing system and method includes a bulk freezing container with a plurality of adjacent elongated chambers adapted for holding the biopharmaceutical fluid. The adjacent elongated chambers have side walls defining a plurality of substantially parallel flow channels between the plurality of adjacent elongated chambers through which a heat transfer medium is passed for heat exchange through the side walls of the elongated chambers to the fluid within the elongated chambers. | 02-20-2014 |
Robert R. Sever, Arlington Heights, IL US
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20120102982 | METHOD AND SYSTEM FOR NUCLEATION CONTROL IN A CONTROLLED RATE FREEZER (CRF) - A method and system for controlled rate freezing and nucleation of materials is provided. The presently disclosed system and method provides the ability to rapidly cool the materials contained in vials or other containers within a cooling unit via forced convective cooling using a laminar and uniform flow of cryogen in proximity to the plurality of vials disposed within the cooling unit. The rapid cooling of the biological materials is achieved by precisely controlling and adjusting the temperature of the cryogen being introduced to the system as a function of time. The presently disclosed methods to systems also provide nucleation control via temperature quench and depressurized nucleation control. | 05-03-2012 |
Robert Rex Sever, Arlington Heights, IL US
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20100242301 | FREEZE-DRYER AND METHOD OF CONTROLLING THE SAME - A freeze-dryer and method of controlling the same is provided. The disclosed freeze-dryer includes a chamber adapted to hold material or product to be freeze-dried; one or more depressurization orifices; a gas pressurization circuit having a source of gas to pressurize the chamber to a prescribed pressure; a depressurization circuit coupled to the chamber via the one or more orifices and having a depressurizing control valve; and a control unit adapted to pressurize the chamber with the source of gas and actuate the depressurizing control valve to depressurize the chamber upon command. The ratio of total depressurization orifice area to the chamber volume is preferably between about 6×10 | 09-30-2010 |
20140325868 | LYOPHILIZATION SYSTEM AND METHOD - System and method for lyophilization or freeze-drying is provided. During the freezing step, the material or solution to be frozen is initially brought to a temperature near or below its freezing temperature after which the pressure in the freeze-dryer chamber is reduced to induce nucleation of the material. | 11-06-2014 |
Sanja Sever, Brookline, MA US
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20100221317 | DYNAMIN MEDIATED DISEASES AND ASSOCIATED METHODS AND PRODUCTS - This invention relates generally to the treatment of cathepsin or dynamin mediated diseases, such as proteinuria, cancer, and cognitive disease and related products. Diagnostic and other assays are also provided, as well as methods for podocyte cell gene transfer. | 09-02-2010 |
20100272709 | CATHEPSIN L MEDIATED DISEASES AND ASSOCIATED METHODS AND PRODUCTS - This invention relates generally to the treatment of cathepsin or dynamin mediated diseases, such as proteinuria, cancer, and cognitive disease and related products. Diagnostic and other assays are also provided, as well as methods for podocyte cell gene transfer. | 10-28-2010 |
20120122968 | USE OF DYNAMIN RING STABILIZERS - There is provided a method for promoting dynamin ring formation and/or maintenance of dynamin rings in a cell, comprising treating the cell with an effective amount of a dynamin ring stabilizer, or a prodrug or pharmaceutically acceptable salt of the dynamin ring stabilizer. The maintenance or accumulation of dynamin ring formation has particular application in the prophylaxis or treatment of a kidney disease or condition characterized by proteinuria. A dynamin ring stabilizer can be any agent that interacts with dynamin to promote dynamin ring assembly and/or inhibit dynamin ring disassembly. There are also provided methods for prophylaxis or treatment of podocyte dysfunction and/or maintaining or inducing actin cytoskeleton formation in a cell utilizing dynamin ring stabilizers, and for screening a test agent for use as a dynamin ring stabilizer. | 05-17-2012 |