Patent application number | Description | Published |
20090287091 | Apparatus and method for generating high resolution image of human body using terahertz electromagnetic wave and endoscope using the same - An apparatus and a method for generating a high resolution image of a human body using a terahertz electromagnetic wave and an endoscope using the same are disclosed. In accordance with the present invention, a third laser beam and a terahertz electromagnetic wave excited by a first laser beam are radiated on a portion of a human body having a contrast agent adhered thereto to generate a high resolution image based on the terahertz electromagnetic wave reflected from the portion of the human body and a second laser beam. | 11-19-2009 |
20100028453 | MULTI -FUNCTIONAL NANOPARTICLES PARTIALLY-DEPOSITED WITH GOLD FILM - Disclosed herein are multifunctional nanoparticles, comprising: polymer nanoparticles formed by loading a drug into a polymer; a gold thin film deposited on a portion of the surface of the polymer nanoparticles; and an antibody to a substance expressed on the surface of a cell to which the drug is to be delivered, the antibody being conjugated to the gold thin film. Also disclosed is a method for preparing multifunctional nanoparticles, the method comprising the steps of: loading a drug into a polymer to prepare polymer nanoparticles; depositing a portion of the surface of the polymer nanoparticles with a gold thin film; conjugating to the gold thin film an antibody to a substance expressed on the surface of a cell to which the drug is to be delivered; and separating from the resulting nanoparticles those in which a portion of the surface of the polymer nanoparticles is deposited with the gold thin film and conjugated with the antibody. Furthermore, disclosed are a composition containing the multifunctional nanoparticles and a method for diagnosing and treating disease using the composition. | 02-04-2010 |
20110151429 | Bioprobe, Method of Preparing the Bioprobe, and Analysis Apparatus and Method Using the Bioprobe - The present invention relates to a bioprobe including a substrate and inorganic nanoparticles attached to the surface of the substrate, a method of preparing the bioprobe, and an analysis apparatus and method using the bioprobe. In the bioprobe according to the present invention, inorganic nanoparticles introduced to the substrate serve as a linker to which a target-specific substance such as an antibody can be bound, and they also increase the surface area of the substrate, thus increasing a surface area where a target substance to be detected can contact the substrate. In this regard, the bioprobe can be effectively used for detection, dosing, or analysis of various biomolecules or other chemical substances. | 06-23-2011 |
20130137114 | Bioprobe, Method of Preparing the Bioprobe, and Analysis Apparatus and Method Using the Bioprobe - The present invention relates to a bioprobe including a substrate and inorganic nanoparticles attached to the surface of the substrate, a method of preparing the bioprobe, and an analysis apparatus and method using the bioprobe. In the bioprobe according to the present invention, inorganic nanoparticles introduced to the substrate serve as a linker to which a target-specific substance such as an antibody can be bound, and they also increase the surface area of the substrate, thus increasing a surface area where a target substance to be detected can contact the substrate. In this regard, the bioprobe can be effectively used for detection, dosing, or analysis of various biomolecules or other chemical substances. | 05-30-2013 |
20150265726 | ORGANIC NANOQUENCHER BASED ON CONJUGATED POLYMER AND PREPARATION METHOD THEREOF - A pH responsive quencher based on a conjugated polymer and responding to an in vivo redox reaction and a preparation method thereof are provided. The pH responsive quencher can evaluate a metabolism environment according to a pH value in vivo with a characteristic that an absorption wavelength band sensitively changes depending on a pH condition. | 09-24-2015 |
20150330977 | MULTISENSING PLATFORM USING NANOPOROUS CANTILEVER SENSOR - Provided is a nanoporous cantilever including a substrate in a shape of a plate, a tip formed at a front end of the substrate, and a nanoporous structure formed on the tip. Due to the nanoporous structure including nanopores and nanochannels formed on the tip, the nanoporous cantilever greatly increases in detection sensitivity for a material to be detected when compared to a cantilever according to a related art, and may obtain a surface-enhanced Raman signal and thus achieve discrimination of a molecule to be detected. | 11-19-2015 |
20150359911 | Aptamer Specific to Integrin alpha-v-beta-3 and Use Thereof - The present invention relates to DNA aptamer specifically binding to integrin α | 12-17-2015 |
20150376405 | BIOENVIRONMENT-SENSITIVE NANOPARTICLE COMPRISING POLYMER HAVING COMPLEMENTARY CHARGES - A bioenvironment-sensitive nanoparticle including a polymer having complementary charges, a method of manufacturing the same, and a pharmaceutical use of the bioenvironment-sensitive nanoparticle are disclosed. The bioenvironment-sensitive nanoparticle can be useful in stably and effectively delivering a target material such as a drug even when used at a small quantity since the nanoparticle is stable in extracellular environments. Also, the bioenvironment-sensitive nanoparticle can be useful in selectively diagnosing or treating cancer cells since the nanoparticle is specific to environments of the cancer cells. | 12-31-2015 |