Segarra
Christiane Segarra, Claret FR
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20120244559 | Nanobeads covered with plasminogen as a direct support for cyclic amplification of the prion protein PrPSC - The present invention relates to an in vitro method for detecting a pathogenic conformational isomer of the prion protein in a sample, said method comprising a preliminary step for capturing the pathogenic conformational isomer by putting the sample into contact with nanobeads covered with a ligand of the pathogenic conformational isomer, and then applying a cyclic amplification of the misfolded prion protein directly on the solid support having captured the pathogenic conformational isomer, and detecting the presence of the pathogenic conformational isomer. The invention also relates to a kit for applying this method and to a method for decontaminating a biological sample. | 09-27-2012 |
Daniel Segarra, Marlborough, MA US
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20140369084 | ELECTRICAL CIRCUIT FOR DELIVERING POWER TO CONSUMER ELECTRONIC DEVICES - An electrical circuit for providing electrical power for use in powering electronic devices is described herein. The electrical circuit includes a power converter circuit that is electrically coupled to an electrical power source for receiving alternating current (AC) input power from the electrical source and delivering direct current (DC) output power to an electronic device. The power converter circuit includes a transformer and a switching device coupled to a primary side of the transformer for delivering power from the electrical power source to a primary side of the transformer. A controller is coupled to a voltage sensor and the switching device for receiving the sensed voltage level from the voltage sensor and transmitting a control signal to the switching device to adjust the voltage level of power being delivered to the electronic device. | 12-18-2014 |
Daniel J. Segarra, Framingham, MA US
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20090009254 | CURRENT SENSE AMPLIFIER FOR VOLTAGE CONVERTER - A thermal calibration circuit for adjusting the gain of a variable gain amplifier, the thermal calibration circuit comprising an interface for receiving a signal that varies with temperature and for providing a signal related to the variation of the temperature; a variable gain amplifier having an input and an output; the signal related to the variation of the temperature being selectively coupled to the input; a circuit at the output of the variable gain amplifier for developing a first current proportional to a difference between a current developed at the output of the variable gain amplifier and a reference current; and the first circuit driving a further circuit to produce a gain control signal for adjusting the gain of the variable gain amplifier. | 01-08-2009 |
20090015331 | CURRENT SENSE AMPLIFIER FOR VOLTAGE CONVERTER - A variable gain amplifier comprising a differential input amplifier comprising a pair of transistors each having an input across which an input voltage is provided, the transistors being coupled such that each transistor is provided in series with a respective current source providing a reference current and whereby a current is developed across a resistor element coupling the transistors that is proportional to the voltage between the inputs; further comprising further transistors each coupled in series with a transistor of the transistor pair, and wherein the further transistors are arranged such that a current is developed in each further transistor due to the voltage provided across the inputs that is substantially equal to, in one further transistor, a sum of the reference current and the current in the resistor element, and in the other further transistor, a difference between the reference current and the current in the resistor element; further comprising a gain stage for developing currents equal to a gain factor multiplied by the sum and difference currents and for developing an output signal proportional to the gain factor multiplied by the current through the resistor element; further comprising an interface for selectively providing a signal proportional to a variable across the inputs of the differential amplifier to drive the output signal to an output value; and a gain setting circuit responsive to the output value that produces a gain setting signal to adjust the gain of the variable gain amplifier. | 01-15-2009 |
Frank Segarra, Merced, CA US
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20100154800 | ENDOTRACHEAL TUBE WITH SECURE COLOR-CODED CONNECTOR AND PACKAGING - An endotracheal tube system having an improved connector to provide a more secure connection to an endotracheal tube. In specific example embodiments, the connector is tapered, is spiraled, or provides threading to improve connection and prevent inadvertent detachment. In certain embodiments, the connector is colorized to correspond to an endotracheal tube size, and in an embodiment, specific packaging permits color to be visualized to aid in proper tube size selection. | 06-24-2010 |
Ignacio Segarra, South Orange, NJ US
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20090028904 | Novel cochleate formulations - A process for producing a small-sized, lipid-based cochleate. Cochleates are derived from liposomes which are suspended in an aqueous two-phase polymer solution, enabling the differential partitioning of polar molecule based-structures by phase separation. The liposome-containing two-phase polymer solution, treated with positively charged molecules such as Ca | 01-29-2009 |
20120294901 | NOVEL COCHLEATE FORMULATIONS - A process for producing a small-sized, lipid-based cochleates. Cochleates are derived from liposomes which are suspended in an aqueous two-phase polymer solution, enabling the differential partitioning of polar molecule based-structures by phase separation. The liposome-containing two-phase polymer solution, treated with positively charged molecules such as Ca | 11-22-2012 |
20140220109 | NOVEL COCHLEATE FORMULATIONS - A process for producing a small-sized, lipid-based cochleates. Cochleates are derived from liposomes which are suspended in an aqueous two-phase polymer solution, enabling the differential partitioning of polar molecule based-structures by phase separation. The liposome-containing two-phase polymer solution, treated with positively charged molecules such as Ca | 08-07-2014 |
Jeffrey Segarra, Medway, MA US
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20090164881 | Scan-to-Redact Searchable Documents - An automatic scan-to-redacted electronic document is described. A user input is received which identifies a scanned document. Then the scanned document is automatically processed to produce a corresponding redacted document which having searchable document text and a document image. The searchable document text includes coded redaction text satisfying defined redaction parameters. The document image includes redacted image areas corresponding to redacted elements. | 06-25-2009 |