Patent application number | Description | Published |
20100028264 | LTBP2 AS A BIOMARKER, THERAPEUTIC AND DIAGNOSTIC TARGET - The invention provides LTBP2, which is associated with cardiovascular diseases, hematological diseases, neurological diseases, cancer, endocrinological diseases, and urological diseases. The invention also provides assays for the identification of compounds useful in the treatment or prevention of cardiovascular diseases, hematological diseases, neurological diseases, cancer, endocrinological diseases, and urological diseases. The invention also features compounds which bind to and/or activate or inhibit the activity of LTBP2 as well as pharmaceutical compositions comprising such compounds. The invention also provides LTBP2 as a biomarker for diseases such as cardiovascular diseases, hematological diseases, neurological diseases, cancer, endocrinological diseases, and urological diseases. | 02-04-2010 |
Patent application number | Description | Published |
20090214477 | Human Marker Genes and Agents for Diagnosis, Treatment and Prophylaxis of Cardiovascular Disorders and Artherosclerosis - The invention relates to novel targets in the screening for compounds useful in the treatment and/or prophylaxis of a disease selected from the group comprising cardiovascular diseases, disorders of lipid metabolism or atherosclerosis. The invention relates to novel compounds for use as a medicament for diseases or conditions involving a disease selected from the group comprising cardiovascular diseases, disorders of lipid metabolism or atherosclerosis. The invention especially relates to antagonists and expression-inhibitory compounds that target G-protein coupled receptors (GPCRs), kinases and proteases, and to methods for identifying such compounds. The invention further relates to methods for identifying these antagonists and expression-inhibitory compounds, and methods for diagnosing a disease selected from the group comprising cardiovascular diseases, disorders of lipid metabolism or atherosclerosis or a susceptibility to such a condition. | 08-27-2009 |
20100104501 | PRSS23 AS A BIOMARKER, THERAPEUTIC AND DIAGNOSTIC TARGET - The invention provides PRSS23, which is associated with cardiovascular diseases, hematological diseases, neurological diseases, cancer, endocrinological diseases, and urological diseases. The invention also provides assays for the identification of compounds useful in the treatment or prevention of cardiovascular diseases, hematological diseases, neurological diseases, cancer, endocrinological diseases, and urological diseases. The invention also features compounds which bind to and/or activate or inhibit the activity of PRSS23 as well as pharmaceutical compositions comprising such compounds. The invention also provides PRSS23 as a biomarker for diseases such as cardiovascular diseases, hematological diseases, neurological diseases, cancer, endocrinological diseases, and urological diseases. | 04-29-2010 |
20110111394 | CTGF AS A BIOMARKER, THERAPEUTIC AND DIAGNOSTIC TARGET - The invention provides CTGF which is associated with the cardiovascular diseases and hematological diseases. The invention also provides assays for the identification of compounds useful in the treatment or prevention of cardiovascular diseases and hematological diseases. The invention also features compounds which bind to and/or activate or inhibit the activity of CTGF as well as pharmaceutical compositions comprising such compounds. The invention also provides CTGF as a biomarker for diseases as cardiovascular diseases and hematological diseases | 05-12-2011 |
Patent application number | Description | Published |
20120141812 | COATING MATERIAL COMPRISING UNSATURATED POLYESTER RESINS AND VINYL ETHERS - The use of a composition which is liquid under standard conditions (20° C., 1 bar) as a coating material, wherein the composition comprises
| 06-07-2012 |
20130344310 | METHOD FOR COATING SURFACES AND USE OF THE ARTICLES COATED USING SAID METHOD - A method for electroless coating of substrates by applying an activating coat of polyelectrolyte or salt with a first aqueous composition; rinsing the activating coat such that the activating coat not being entirely removed; contacting and coating of the activated surfaces that have remained after rinsing with an aqueous composition in the form of a solution, emulsion or suspension, to form an organic secondary coat; and drying. The activating coat is a solution, emulsion or suspension containing a anionic polyelectrolyte or at least one anionic salt in solution in water. The aqueous composition forming the secondary coat has constituents which can be precipitated, deposited or salted out and which are anionically, zwitterionically, sterically or cationically stabilized. The dry film formed in the process, comprising the activating coat and the secondary coat, has a thickness of at least 1 μm. | 12-26-2013 |
20140004266 | METHOD FOR COATING SURFACES AND USE OF THE OBJECTS COATED USING SAID METHOD | 01-02-2014 |
20150079277 | METHOD FOR COATING METALLIC SURFACES OF SUBSTRATES, AND OBJECTS COATED ACCORDING TO SAID METHOD - A method and composition for coating surfaces, a corresponding coating and the use of objects coated according to said method. A cleaned, metallic surface is contacted with an aqueous composition that is a dispersion or suspension, and drying and/or baking the organic coating or optionally, drying the organic coating and coating with an equivalent or additional coating composition prior to a drying and/or baking. The aqueous composition has a pH of 4 to 11 and contains an anionic polyelectrolyte in a quantity of 0.01 to 5.0 wt. % relative to the total mass of the composition, which may have a solids content of from 2 to 40 wt. %. The solids have an average particle size from 10 to 1000 nm. A coating forms on the basis of an ionogenic gel which binds cations released from the metallic surface that originate from a pretreatment stage or from the contacting. | 03-19-2015 |
Patent application number | Description | Published |
20130320629 | Radial Shaft Seal Ring - A radial shaft seal ring includes a reinforcing ring and an elastomer part connected to the reinforcing ring. The elastomer part includes a dynamic sealing lip having a radial sealing lip section and an axial sealing lip section. The axial sealing lip section includes a sealing edge for sealing abutment on a shaft. The sealing edge is disposed on an inner peripheral wall of the axial sealing lip section and the inner peripheral wall faces towards the shaft. The axial sealing lip section further includes a reinforcing structure. | 12-05-2013 |
20140151967 | SEALING LIP AND SEAL - A sealing lip seals a first space from a second space with respect to a liquid medium present in the first space. The sealing lip has abutment surface configured to abut on a sealing surface of a component that is movable relative to the sealing lip along a direction of movement. A groove is defined in the abutment surface and pumps any liquid medium present in the groove towards the first space along the direction of movement. The groove extends completely within the abutment surface and is enclosed by the abutment surface, such that it does not intersect either lateral edge of the sealing lip. | 06-05-2014 |
20140175748 | SEAL AND METHOD FOR MANUFACTURING THEREOF - A seal includes a sealing lip having a sealing region with a pumping structure that can abut on a first component. The pumping structure causes a liquid medium to move in a direction from a first axial side of the seal towards or to a second axial side of the seal when the first component rotates relative to a second component. The pumping structure includes at least one pumping groove that extends along a direction of extension and at least one retaining structure disposed in the at least one pumping groove. The at least one retaining structure reduces a cross-section of the at least one pumping groove, in at least one direction perpendicular to the direction of extension, to a value of between 50% and 90% of an extension of the cross-section of the pumping groove outside the at least one retaining structure along the at least one direction. | 06-26-2014 |
20150042044 | SEALING ASSEMBLY - A sealing assembly includes a seal support having a support ring made from an elastomeric material, at least one seal element having a ring made from a polymer material, and an abutment ring against which a radial portion of the seal element axially abuts. The seal element is connected in a materially-bonded manner to the support ring along a first radially outer portion of the seal element, and the seal element axially abuts on the abutment ring along a second radially inner portion of the seal element. The seal element and the abutment ring are free of any connection along the second radially inner portion of the seal element. | 02-12-2015 |
Patent application number | Description | Published |
20140027444 | HEATING DEVICE - The invention relates to a heating device having a housing and having a fluid duct which is arranged in said housing and which has a fluid inlet and a fluid outlet, wherein, in the housing, there is provided an element which generates an alternating magnetic field and which is separated from the fluid duct in a sealed manner by at least one wall, wherein furthermore, at least one metallic areal heating element is provided which can be heated by the alternating magnetic field, wherein the at least one areal heating element is arranged in the fluid duct. | 01-30-2014 |
20140352936 | HEAT EXCHANGER - A plate-type heat exchanger, in particular for motor vehicles, is described which includes plate pairs. In one example, a plate pair includes a first plate and a second plate that form a first flow path and a second flow path between the plates. In this configuration, the first and the second plate are associated with a first attachment plate and a second attachment plate, respectively. A third flow path is formed between the first plate and the second attachment plate and the first flow path is formed between the second plate and the first attachment plate. Alternatively, the third flow path is formed between the first plate and the first attachment plate and the first flow path is formed between the second plate and the second attachment plate. A spatial region for a fourth flow path may also be formed between adjacent plate pairs. | 12-04-2014 |
20140374072 | KIT FOR A HEAT EXCHANGER, A HEAT EXCHANGER CORE, AND HEAT EXCHANGER - A kit for producing heat exchangers includes at least two types of heat exchanger cores in order to produce more than two different heat exchangers. The kit has a first type of heat exchanger core with a plurality of pairs of plates in order to produce a plurality of parallel flow paths between the plate pairs and a second type of heat exchanger core with a plurality of groups of three plates in order to produce a plurality of second parallel flow paths, one flow path being produced between two of each three plates. | 12-25-2014 |
20140374074 | HEAT EXCHANGER - The invention relates to a plate-type heat exchanger, in particular for motor vehicles, having a plurality of plate pairs for forming first, second and third flow paths, a spatial region for fourth flow paths being formed between adjacent plate pairs, the plate pairs being formed from at least one first plate and a second plate in order to form the first flow paths and the second flow paths between the first and second plates, the third flow paths also being formed between the first plate and the second plate or an attachment plate being placed upon the firs and/or the second plate in order to form the third flow path between the first plate and the attachment plate and/or between the second plate and the attachment plate. | 12-25-2014 |
20140374076 | HEAT EXCHANGER - A plate-type heat exchanger, in particular for motor vehicles, is provided that includes a plurality of plate groups in order to form first and second and/or third flow paths, a spatial region for fourth flow paths being formed between adjacent plate groups, the plate groups having at least one plate pair having a first and second plate in order to form the first flow paths and the second flow paths, wherein a third plate can be arranged in interaction with one of the first or one of the second plates in order to form the third flow path. | 12-25-2014 |
20140374408 | HEAT EXCHANGER DEVICE AND HEATER - A heat exchanger device for a heater a motor vehicle, having a housing with at least one fluid channel disposed therein, with a fluid inlet and a fluid outlet, an element generating an alternating magnetic field, and at least one, preferably metallic, flat heating element around which a fluid can flow on one or both sides, whereby at least one further flat heating element is provided, which is configured to divide the at least one fluid channel into subchannels. A heater with a heat exchanger device is also provided. | 12-25-2014 |
20140374409 | HEATER - A heater with a housing with a fluid channel, disposed therein, with a fluid inlet and a fluid outlet, whereby a coil, which generates an alternating magnetic field and is separated sealed from the fluid channel by a coil housing, is provided in the housing, whereby furthermore at least one metallic flat heating element is provided, which can be heated by the alternating magnetic field. The at least one flat heating element is disposed in the fluid channel, whereby the fluid channel is divided at least into a first channel and a second channel. Walls bounding the channels are formed by the coil housing and/or by a flat heating element. | 12-25-2014 |
20150131979 | HEATING DEVICE - A heating device is provided with plates stacked one on top of another. At least one first fluid channel is formed in a fluid-tight manner between a first plate package with a first and a second plate. An electrical heating element is arranged between a first plate of the first plate package and an additional plate. The electrical heating element is accommodated between the two plates in a sealed manner and is electrically insulated, wherein an inlet-side and an outlet side fluid connection of the first fluid channel is arranged on the second plate of the first plate package. The electrical heating element has a connection device for electrical contacting, which is connected to the electrical heating element and protrudes through a window in the second plate of the first plate package, wherein the fluid connections and the window are arranged adjacent to opposing lateral edges of the second plate. | 05-14-2015 |
Patent application number | Description | Published |
20090095015 | HEAT EXCHANGER IN PARTICULAR WITH COLD RESERVOIR - The invention relates to a heat exchanger, in particular, an evaporator ( | 04-16-2009 |
20100116474 | HEAT EXCHANGER - A heat exchanger is provided, particularly for a heating or air conditioning system for motor vehicles, comprising at least one inlet channel and at least one outlet channel and at least one collector, which has at least two metal sheets or plates abutting each other, and a flow device, through which a first medium can flow, while a second medium can flow around said flow device. The first medium is distributed by an inlet channel to the collector and to the flow device and can be conducted to an outlet channel, whereby at least one further channel for distributing the coolant is provided, which is connected in a communicating manner via at least one opening to the inlet channel. | 05-13-2010 |
20140027096 | HEAT EXCHANGER - A heat exchanger, in particular for a heating or air-conditioning system in a motor vehicle, having an evaporator unit to which a refrigerant medium can be supplied via a distribution unit and through which said refrigerant medium flows and around which said refrigerant medium flows after only one diversion (two-block design) at the bottom in a diversion unit, wherein the distribution unit is designed to effect a uniform distribution of the refrigerant medium over the hill width of the evaporator. | 01-30-2014 |