Patent application number | Description | Published |
20120251618 | DELIVERY AND FORMULATION OF ENGINEERED NUCLEIC ACIDS - Provided are formulations, compositions and methods for delivering biological moieties such as modified nucleic acids into cells to modulate protein expression. Such compositions and methods include the delivery of biological moieties, and are useful for production of proteins. | 10-04-2012 |
20130115272 | MODIFIED NUCLEOSIDES, NUCLEOTIDES, AND NUCLEIC ACIDS, AND USES THEREOF - The present disclosure provides modified nucleosides, nucleotides, and nucleic acids, and methods of using them. | 05-09-2013 |
20130156849 | MODIFIED NUCLEOSIDE, NUCLEOTIDE, AND NUCLEIC ACID COMPOSITIONS - The present disclosure provides, inter alia, formulation compositions comprising modified nucleic acid molecules which may encode a protein, a protein precursor, or a partially or fully processed form of the protein or a protein precursor. The formulation composition may further include a modified nucleic acid molecule and a delivery agent. The present invention further provides nucleic acids useful for encoding polypeptides capable of modulating a cell's function and/or activity. | 06-20-2013 |
20130244282 | METHOD OF PRODUCING ANTIBODIES - Provided are compositions and methods for delivering biological moieties such as modified nucleic acids into cells to modulate protein expression. Such compositions and methods include the use of modified messenger RNAs, and are useful for production of proteins. | 09-19-2013 |
20130245103 | MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF FACTOR IX - Provided are formulations, compositions and methods for delivering biological moieties such as modified nucleic acids into cells to modulate protein expression. Such compositions and methods include the delivery of biological moieties, and are useful for production of proteins. | 09-19-2013 |
20130245104 | METHOD FOR PRODUCING A PROTEIN OF INTEREST IN A PRIMATE - The present disclosure provides, inter alia, formulation compositions comprising modified nucleic acid molecules which may encode a protein, a protein precursor, or a partially or fully processed form of the protein or a protein precursor. The formulation composition may further include a modified nucleic acid molecule and a delivery agent. The present invention further provides nucleic acids useful for encoding polypeptides capable of modulating a cell's function and/or activity. | 09-19-2013 |
20130245105 | DLIN-KC2-DMA LIPID NANOPARTICLE DELIVERY OF MODIFIED POLYNUCLEOTIDES - The present disclosure provides, inter alia, formulation compositions comprising modified nucleic acid molecules which may encode a protein, a protein precursor, or a partially or fully processed form of the protein or a protein precursor. The formulation composition may further include a modified nucleic acid molecule and a delivery agent. The present invention further provides nucleic acids useful for encoding polypeptides capable of modulating a cell's function and/or activity. | 09-19-2013 |
20130253043 | MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF G-CSF - The present disclosure provides, inter alia, formulation compositions comprising modified nucleic acid molecules which may encode a protein, a protein precursor, or a partially or fully processed form of the protein or a protein precursor. The formulation composition may further include a modified nucleic acid molecule and a delivery agent. The present invention further provides nucleic acids useful for encoding polypeptides capable of modulating a cell's function and/or activity. | 09-26-2013 |
20130259923 | MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF SECRETED PROTEINS - The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules. | 10-03-2013 |
20130259924 | MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF BIOLOGICS AND PROTEINS ASSOCIATED WITH HUMAN DISEASE - The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules. | 10-03-2013 |
20130266640 | MODIFIED NUCLEOSIDE, NUCLEOTIDE, AND NUCLEIC ACID COMPOSITIONS - The present disclosure provides, inter alia, formulation compositions comprising modified nucleic acid molecules which may encode a protein, a protein precursor, or a partially or fully processed form of the protein or a protein precursor. The formulation composition may further include a modified nucleic acid molecule and a delivery agent. The present invention further provides nucleic acids useful for encoding polypeptides capable of modulating a cell's function and/or activity. | 10-10-2013 |
20140010861 | MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF PROTEINS ASSOCIATED WITH HUMAN DISEASE - The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules. | 01-09-2014 |
20140243399 | ENGINEERED NUCLEIC ACIDS AND METHODS OF USE THEREOF - Provided are compositions and methods for delivering biological moieties such as modified nucleic acids into cells to modulate protein expression. Such compositions and methods include the use of modified messenger RNAs, and are useful to treat or prevent diseases, disorders or conditions, or to improve a subject's heath or wellbeing. | 08-28-2014 |
20150056253 | ENGINEERED NUCLEIC ACIDS AND METHODS OF USE THEREOF - Provided are compositions and methods for delivering biological moieties such as modified nucleic acids into cells to kill or reduce the growth of microorganisms. Such compositions and methods include the use of modified messenger RNAs, and are useful to treat or prevent microbial infection, or to improve a subject's heath or wellbeing. | 02-26-2015 |
20150064235 | MODIFIED POLYNUCLEOTIDES - The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules. | 03-05-2015 |
20150064236 | MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF PROTEINS - The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules. | 03-05-2015 |
20150064725 | ENGINEERED NUCLEIC ACIDS AND METHODS OF USE THEREOF - Provided are compositions and methods for delivering biological moieties such as modified nucleic acids into cells to modulate protein expression. Such compositions and methods include the use of modified messenger RNAs, and are useful for production of proteins. | 03-05-2015 |
20150086614 | MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF CYTOPLASMIC AND CYTOSKELETAL PROTEINS - The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules. | 03-26-2015 |
20150111248 | IN VIVO PRODUCTION OF PROTEINS - The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules. | 04-23-2015 |
20150141499 | ENGINEERED NUCLEIC ACIDS AND METHODS OF USE THEREOF - Provided are compositions and methods for delivering biological moieties such as modified nucleic acids into cells to kill or reduce the growth of viruses. Such compositions and methods include the use of modified messenger RNAs, and are useful to treat or prevent viral infection, or to improve a subject's heath or wellbeing. | 05-21-2015 |
20150246139 | MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF NUCLEAR PROTEINS - The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules. | 09-03-2015 |
Patent application number | Description | Published |
20120207163 | FRAME DELIVERY PATH SELECTION IN HYBRID COMMUNICATION NETWORKS - A hybrid network device can implement a frame delivery path selection mechanism for communicating with other network devices in a hybrid communication network. In one embodiment, the hybrid network device determines a preferred network interface among a plurality of network interfaces of the hybrid network device for communicating with a second network device. The hybrid network device determines an address associated with the preferred network interface of the hybrid network device. The hybrid network device transmits an address announcement message comprising an indication of the address associated with the preferred network interface from the hybrid network device to the second network device to cause the second network device to use the address associated with the preferred network interface for communicating with the hybrid network device. | 08-16-2012 |
20120236758 | HYBRID NETWORKING SIMPLE-CONNECT SETUP USING FORWARDING DEVICE - A simple connect setup function for hybrid networks is provided that allows a user to add devices optionally having a number of different network interfaces (e.g., that facilitate communications using different network technologies or protocols) to a hybrid network in a single, simplified operation that alleviates the need for the user to individually connect and/or configure a multitude of different network interfaces. The simple connect setup function also alleviates the need for the user to know on which devices the simple connect setup function must be activated for successful simple connect setup. | 09-20-2012 |
20120239744 | HYBRID NETWORKING SIMPLE-CONNECT SETUP USING PROXY DEVICE - A simple connect setup function for hybrid networks is provided that allows a user to add devices optionally having a number of different network interfaces (e.g., that facilitate communications using different network technologies or protocols) to a hybrid network in a single, simplified operation that alleviates the need for the user to individually connect and/or configure a multitude of different network interfaces. The simple connect setup function also alleviates the need for the user to know on which devices the simple connect setup function must be activated for successful simple connect setup. | 09-20-2012 |
20120239929 | HYBRID NETWORKING MASTER PASSPHRASE - A method and apparatus for providing a passphrase-based security setup for a hybrid network including multiple network interfaces configured for communicating over one or more communication media are provided. The method includes receiving a passphrase from a user at a network interface of the multiple network interfaces. The received passphrase is then used for authenticating the device for one or more network interfaces. The authentication can be performed irrespective of a communication medium used by the network interfaces. | 09-20-2012 |
20130114598 | PACKET ORDERING BASED ON DELIVERY ROUTE CHANGES IN COMMUNICATION NETWORKS - A hybrid network device can implement functionality to detect a change in a packet route associated with one or more packets sharing a common route, and to manage out-of-order packet arrival. In a hybrid communication network, a first network device can communicate with a second network device via a plurality of packet routes. The first network device can detect one or more route change indicators that are indicative of a change in a packet route between the first network device and the second network device from a first packet route to a second packet route based, at least in part, on a plurality of packets received from the second network device. Based on the route change indicators, it may be determined whether the plurality of packets were received according to a predetermined order and if the plurality of packets should be re-ordered based on the predetermined order. | 05-09-2013 |